Clinical trials
Chronic Disease Prevention clinical trials
Below are recruiting chronic disease prevention clinical trials, each written for real people, not researchers. We’re tracking 200 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06602544Recruiting
Robotic suit to prevent freezing in Parkinson's
This study tests a robotic suit designed to help prevent freezing of gait (a sudden feeling of being stuck) in people with Parkinson's disease. You'll attend 8 visits to see if the suit can improve your walking and reduce falls.
Allston, MassachusettsAges 18–90 - NCT05356104RecruitingPhase 2
GLP-1 treatment to slow small blood-vessel brain damage
This Phase 2 study tests whether a GLP-1–like medicine can slow worsening “small vessel” disease changes in the brain and related walking and thinking problems. It aims to see if the treatment can prevent progression in people who already show early brain changes on MRI.
Wenzhou, ZhejiangAges 55–80 - NCT06756061RecruitingPhase 2
Ruxolitinib and steroids for chronic graft-versus-host disease
This trial tests whether adding ruxolitinib to standard steroid treatment works better than steroids alone for people with moderate to severe chronic graft-versus-host disease (cGVHD). cGVHD is a condition where donor immune cells attack the body after a stem cell transplant.
Seoul, Banpo-daero/Seocho-guAges 19 years+ - NCT06667700RecruitingPhase 3
A study of the antiviral molnupiravir for high-risk people with COVID-19
This study tests an antiviral pill called molnupiravir to see if it can prevent severe COVID-19 in people who are at high risk and cannot take Paxlovid. If you have mild to moderate COVID-19 symptoms and certain health risks, you may be able to join.
Cullman, AlabamaAges 18 years+ - NCT04286399RecruitingPhase 4
Prevention trial for heart outcomes in people with type 2 diabetes
This Phase 4 trial studies an approach to help prevent heart problems in adults with type 2 diabetes who are at higher heart risk. It may help reduce future cardiovascular events by testing medications for safety and benefit in this group.
SingaporeAges 40 years+ - NCT03083184RecruitingPhase 3
Ethanol lock solution to prevent catheter infections
This Phase 3 study tests whether a medicine-filled “lock” put into a dialysis catheter can lower the risk of infections. It is meant for people on regular dialysis with a tunnelled catheter who already have it in place.
Clermont-FerrandAges 18 years+ - NCT07253259RecruitingEarly Phase 1
Cell therapy for hard-to-treat chronic graft-versus-host disease
This study tests a new cell therapy called GT729 for people with chronic graft-versus-host disease (cGVHD) that hasn't improved with at least two previous treatments. The therapy is given as an injection and aims to help control the immune system reaction that causes cGVHD.
Tianjin, Tianjin MunicipalityAges 18–65 - NCT06914635Recruiting
Immunotherapy hub study for liver tumor patients
This trial is checking how the immune system works in people with primary liver cancer, looking at ways to prevent infections and manage the tumor. It is an observational study—meaning no new treatments are given—so it helps doctors learn more without adding extra medications.
Pavia, PaviaAges 18–90 - NCT06942611Recruiting
Electrical brain stimulation for chronic pain from nerve inflammation
This study tests a noninvasive brain stimulation technique (transcranial electrical stimulation) to see if it can reduce chronic pain in people with conditions like multiple sclerosis or neuromyelitis optica. It aims to offer a new, drug-free option for pain relief without major side effects.
BeijingAges 18–65 - NCT06926595RecruitingPhase 2
Stem cell transplant with low-dose chemo for graft-versus-host disease prevention
This trial tests a stem cell transplant using a reduced-intensity chemotherapy regimen and a low dose of a drug called cyclophosphamide after the transplant to help prevent graft-versus-host disease (GVHD), a common complication where donor cells attack the recipient's body. It is for people with certain blood cancers or bone marrow disorders who have a suitable donor.
Hershey, PennsylvaniaAges 18 years+ - NCT07463664Recruiting
Drug-coated balloons for blocked heart arteries
This trial tests whether a drug-coated balloon, used without a permanent stent, can safely open completely blocked heart arteries that have been blocked for at least 3 months. It may offer an option that avoids leaving a metal stent behind.
Beijing, Beijing MunicipalityAges 18–80 - NCT07023523Recruiting
Controlling brain activity for chronic pain
This study tests if people with fibromyalgia can learn to control their own brain activity using real-time feedback from an MRI machine to reduce pain. It is designed to help those with long-term chronic pain find new ways to manage it.
Boston, MassachusettsAges 18–65 - NCT07246031RecruitingPhase 2
BPC2001 to Prevent Graft-Versus-Host Disease After Stem Cell Transplant
This trial tests a new drug, BPC2001, to see if it can prevent graft-versus-host disease (a common complication where donor cells attack the patient's body) in people receiving a half-matched stem cell transplant from a family donor. It may be an option for adults with certain blood cancers who are planning their first transplant.
Beijing, Beijing MunicipalityAges 18–65 - NCT07611747RecruitingPhase 4
Ultrasound Screening to Prevent Heart Disease in Rheumatic Patients
This study tests whether using ultrasound to look at arteries in the neck can help prevent heart attacks and strokes in people with inflammatory joint diseases like rheumatoid arthritis or lupus. Researchers will use the results to guide treatment decisions.
Alicante, AlicanteAges 50 years+ - NCT06224140Recruiting
Dialysis without heparin: a safety study
This study tests whether dialysis can be done safely without using heparin (a blood thinner) in people with end-stage kidney disease. If successful, it could reduce the need for blood-thinning medications and their associated risks.
Marseille, Bouches du RhôneAges 18 years+ - NCT05282654Recruiting
Using phone symptom check-ins to prevent problems after discharge
This trial studies a real-time symptom monitoring system (ePROs) that collects your symptoms during care transitions, like when you leave the hospital. The goal is to catch warning signs early so you can avoid adverse events after discharge.
Boston, MassachusettsAges 18 years+ - NCT06656988RecruitingPhase 3
Saving kidney function during leg artery treatment with carbon dioxide
This trial tests if using carbon dioxide gas instead of standard dye during a leg artery procedure can protect the kidneys. It is for people with blocked leg arteries who also have reduced kidney function.
InnsbruckAges 18 years+ - NCT02817360RecruitingPhase 4
Preventing heart events in people with type 2 diabetes
This trial tests a heart-focused prevention approach to lower the risk of cardiac (heart) events in adults with type 2 diabetes. It may help by targeting early stress on the heart measured with a specific blood test.
Mödling, Lower AustriaAges 18 years+ - NCT07860216RecruitingPhase 3
RSV vaccine safety and immune response study for older adults
This trial tests an experimental vaccine to protect older adults against respiratory syncytial virus (RSV), a common virus that can cause serious lung infections. It looks at whether the vaccine is safe and how well it boosts immunity. If you are healthy and over 60, you might be able to join.
GuiZhou, GuizhouAges 60 years+ - NCT07282301Recruiting
Filter to catch debris during leg artery cleaning
This trial tests a special filter that catches debris during a procedure to clear blockages in the leg artery (the one behind the knee). It aims to reduce the risk of debris traveling to smaller blood vessels, which can cause complications. If you have a hardened leg artery and plan to have plaque removal before a stent or balloon, this study may be for you.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07270406Recruiting
Healthy habits for better sleep in people with HIV and pain
This study tests a healthy behaviors program to help prevent insomnia in people with HIV who also have ongoing pain. If you have trouble sleeping and chronic pain, this program may help improve your sleep and well-being.
St Louis, MissouriAges 25–65 - NCT06911749Recruiting
Using MSOT and MRI to measure bowel transit in children
This trial tests whether two imaging techniques, MSOT and MRI, can safely and non-invasively measure how long it takes for food to move through the bowels in children with chronic constipation or other bowel emptying problems. It may help doctors better understand and treat these conditions.
Erlangen, BavariaAges 1 year+ - NCT07202559Recruiting
Preventing Pancreatitis After Shock Wave Therapy for Pancreatic Stones
This study tests whether a combination of an NSAID (indomethacin) given rectally plus extra fluids through an IV can prevent pancreatitis after shock wave therapy for pancreatic stones. It may help reduce inflammation and protect your pancreas during treatment.
BaotouAges 18–85 - NCT06963320RecruitingPhase 2
Preventing blood clots after knee replacement with H001
This trial tests whether an experimental capsule (H001) can prevent dangerous blood clots after knee replacement surgery. It is for people who are scheduled for a first-time total knee replacement and are willing to take the study drug instead of standard blood thinners.
Shanghai, Shanghai MunicipalityAges 18–74
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Common questions
- Are there clinical trials for chronic disease prevention?
- Yes. Clin2 currently lists 200 recruiting chronic disease prevention studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease prevention trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease prevention trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.