Clinical trials
Cirrhosis clinical trials
Below are recruiting cirrhosis clinical trials, each written for real people, not researchers. We’re tracking 271 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03208868Recruiting
Amino acid drink to help rebuild muscle in cirrhosis
This trial tests whether a special mix of amino acids (building blocks for muscle) can help reverse muscle loss in people with cirrhosis. It aims to improve muscle health while keeping you safe from known complications of liver disease.
Cleveland, OhioAges 18–70 - NCT03584204Recruiting
Imaging study for people with liver cirrhosis
This study looks at how liver cirrhosis shows up on non-invasive imaging like CT scans, and how those findings relate to outcomes. It may help researchers better understand what scan patterns could signal disease severity.
BonnAges 18–80 - NCT04250259RecruitingPhase 2
SAMe treatment study for alcoholic cirrhosis
This Phase 2 study tests whether SAMe can help people with alcoholic cirrhosis (scarred liver) who are in early to mid stages. It may also include healthy volunteers to compare safety and blood/body measurements.
Los Angeles, CaliforniaAges 18–70 - NCT04448028RecruitingPhase 4
Stopping acid pills in liver cirrhosis: test placebo effect
This study tests whether stopping proton-pump inhibitor (PPI) acid-reducing medication is safe and works as expected for people with liver cirrhosis. Participants switch to either the study medication or a placebo (inactive pill) under close monitoring.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT04502719Recruiting
Testing nutrition screening in people with liver cirrhosis
This study compares different ways of checking nutrition problems in people with liver cirrhosis. It may help doctors choose the best screening tool to spot risk earlier and guide care.
Barcelona, CataloniaAges 18–100 - NCT04588077RecruitingPhase 4
Two-dose vs three-dose hepatitis B vaccine for cirrhosis
This study compares giving the hepatitis B vaccine in 2 doses versus 3 doses for people with cirrhosis who do not yet have protection against hepatitis B. It may help your care team choose the schedule most likely to build lasting immunity.
Baltimore, MarylandAges 18 years+ - NCT04613921Recruiting
Liver transplant study for severe worsening liver failure
This study looks at when liver transplant is offered and what outcomes happen in people with cirrhosis who have severe “acute-on-chronic” worsening. It may help doctors decide which patients benefit most from transplant and improve care after listing or not listing.
Los Angeles, CaliforniaAges 18–80 - NCT04689152RecruitingPhase 3
Cell treatment via liver artery catheter for alcoholic cirrhosis
This Phase 3 trial tests whether a cell medicine called Cellgram-LC, delivered through a catheter into the liver artery, is safer and works better for people with alcoholic cirrhosis. It may help improve outcomes in people with more advanced liver scarring.
Bucheon-siAges 20–71 - NCT04767945Recruiting
Cirrhosis patient hospital registry
This study keeps a record of people who have liver cirrhosis and were admitted to the hospital after a worsening event. It may help doctors better understand what leads to hospital stays and improve future care.
Banská BystricaAges 19 years+ - NCT04801290Recruiting
TIPS procedure for people with worsening liver cirrhosis
This trial studies the TIPS procedure in people with decompensated (worsening) liver cirrhosis to see how it helps. You may be considered if you need a TIPS procedure and can receive care at the study hospital.
Hanover, Lower SaxonyAges 18–99 - NCT04873102RecruitingPhase 2
Danazol for low blood counts in some people with cirrhosis
This Phase 2 study tests danazol to improve low blood counts (low white blood cells and/or low platelets) in people with certain types of cirrhosis. It also looks at who may benefit, especially those with specific inherited blood-telomere changes.
Los Angeles, CaliforniaAges 18 years+ - NCT04874428RecruitingPhase 1
Blood thinner pills in people with mild-to-moderate cirrhosis
This early study tests whether the blood thinner pills rivaroxaban and apixaban can be used safely in people with liver cirrhosis that is not too severe. It may help doctors understand the safest way to prevent or treat blood clots in this group.
BernAges 18 years+ - NCT04932577RecruitingPhase 2/Phase 3
Fecal transplant to treat complications of liver cirrhosis
This trial studies whether transferring healthy gut bacteria (from a donor sample) can improve outcomes for people with liver cirrhosis who have worsening complications. It may help by changing the gut microbiome, which can influence inflammation and liver health.
AarhusAges 18–75 - NCT05061576Recruiting
At-home exercise program for people with liver scarring
This study tests an at-home, guided physical exercise plan for people with liver cirrhosis. It may help improve strength and day-to-day functioning while monitoring safety.
StockholmAges 18 years+ - NCT05093881Recruiting
Follow-up study for people treated for alcoholic liver scarring
This study checks on people who previously received Cellgram-LC for alcohol-related liver cirrhosis (liver scarring) in an earlier trial. It helps researchers learn long-term safety and outcomes after that treatment.
Bucheon-siAges Any age - NCT05166499Recruiting
Amino acids to help rebuild muscle in liver cirrhosis
This trial tests whether a special amino-acid supplement can help reverse muscle loss in people with cirrhosis (scarring of the liver). It may help maintain or improve muscle strength and overall function, but eligibility depends on your liver status and overall health.
Cleveland, OhioAges 21–65 - NCT05201404RecruitingPhase 3
Namodenoson for advanced liver cancer with moderate cirrhosis
This Phase 3 trial studies whether namodenoson can slow or control advanced hepatocellular carcinoma (liver cancer) in people whose cirrhosis is in a specific middle range. It may help if standard treatments have not worked or the cancer has spread and is not expected to be cured.
Dallas, TexasAges 18 years+ - NCT05205954Recruiting
Home hospital care for adults with advanced liver disease
This pilot study tests whether a “home hospital” program can safely care for people with advanced liver disease after they are admitted to the hospital. It may reduce time in the hospital while still treating serious complications like fluid buildup, breathing fluid, or confusion from liver disease.
Boston, MassachusettsAges 18 years+ - NCT05325424Recruiting
Laparoscopic spleen surgery for people with cirrhosis
This study looks at whether removing the spleen using keyhole surgery can improve “liver reserve function” in people with cirrhosis. It may be considered for patients who have an enlarged spleen and very low platelets, but it also has several safety exclusions.
Yangzhou, JiangsuAges 18 years+ - NCT05325437Recruiting
Laparoscopic spleen surgery to protect liver function in cirrhosis
This trial looks at whether a minimally invasive spleen surgery (with a specific vein-disconnection procedure) can better protect liver function in people with cirrhosis who have had variceal bleeding. It may help reduce stress on the liver after treatment, but you must meet several safety criteria.
Yangzhou, JiangsuAges 18 years+ - NCT05338294Recruiting
Tested surgery to help immune function in cirrhosis
This study looks at whether a type of keyhole spleen surgery plus cutting a large vein can improve immune function in people with cirrhosis. It may help reduce immune problems that can happen after complications like bleeding from varices (enlarged veins in the esophagus/stomach).
Yangzhou, JiangsuAges 18 years+ - NCT05346393Recruiting
TIPS procedure for kidney failure in people with cirrhosis
This trial studies whether a liver procedure called TIPS can help people with cirrhosis who develop sudden kidney failure (HRS-AKI). It aims to improve kidney function and overall outcomes, but participation depends on several safety checks.
AachenAges 18–80 - NCT05475015Recruiting
3D MRI scan to assess liver scarring and pressure
This study tests whether a special 3D MRI scan (3D-MRE) can measure liver scarring and the high pressure in the liver called portal hypertension. It may help your team use imaging to understand how severe your liver disease is, especially when a pressure test (HVPG) is being considered.
Shenyang, LiaoningAges 18–75 - NCT05667805RecruitingPhase 4
Testing blood clotting in people with liver cirrhosis
This Phase 4 study looks at how clotting measurements relate to bleeding risk in people with liver cirrhosis who need a planned liver procedure. The study may help doctors understand what coagulation results mean when doing these procedures safely.
ViennaAges 18 years+
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Common questions
- Are there clinical trials for cirrhosis?
- Yes. Clin2 currently lists 271 recruiting cirrhosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cirrhosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cirrhosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.