Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07205120Recruiting
Fluid-guided heart failure treatment study
This trial tests a new way to manage fluid levels in people hospitalized for heart failure. It aims to help doctors adjust treatment to keep you from coming back to the hospital.
Cleveland, OhioAges 21 years+ - NCT07209098Recruiting
Heart failure study testing CCM therapy
This study tests a therapy called Cardiac Contractility Modulation (CCM) for people with heart failure. It uses a device to help the heart pump more strongly, and researchers compare it to standard care using patient records.
Marlton, New JerseyAges 18 years+ - NCT07247032Recruiting
Heart failure management with remote monitoring
This trial tests whether remote monitoring of your implanted heart device can help your doctors better manage your heart failure. It is for people with certain types of pacemakers or defibrillators who are willing to share their device data remotely.
ParisAges 18–85 - NCT07680634Recruiting
Heart failure care with remote home monitoring
This trial tests a new way of caring for heart failure that combines in-person clinic visits with at-home monitoring using digital tools. If you join, you may be able to have more of your check-ups from home, which could be more convenient and help your care team catch problems early.
Amsterdam, UtrechtAges 18 years+ - NCT07037459RecruitingPhase 3
A study of a new drug for heart failure with obesity
This trial tests a medication called maridebart cafraglutide for people with heart failure (where the heart doesn't pump as well as it should) and obesity. The goal is to see if it can help improve symptoms and outcomes.
Birmingham, AlabamaAges 18–99 - NCT07252531Recruiting
BrioVAD heart pump study for advanced heart failure
This trial tests a new heart pump (BrioVAD) for people with very advanced heart failure. It aims to help those who are not getting better with standard treatments or who need extra support like IV medicines or a balloon pump.
RotterdamAges 18 years+ - NCT07263035RecruitingPhase 4
Urine sodium-guided diuretic strategy for heart failure
This trial tests a new way to adjust diuretic (water pill) doses based on urine sodium levels in patients hospitalized for worsening heart failure. The goal is to improve fluid removal and get patients home sooner.
Lakeland, FloridaAges 18 years+ - NCT07272902Recruiting
Atrial fibrillation treatment: Ablation vs. medication
This trial compares two ways to treat atrial fibrillation in people with heart failure where the heart's pumping strength is still normal. You'll either get a procedure called ablation to restore normal rhythm or medication to control your heart rate. The goal is to see which approach works better for people like you.
Halifax, Nova ScotiaAges 18 years+ - NCT07313657Recruiting
Heart health and well-being support study
This study tests a web tool designed to improve mental well-being for adults with heart failure. If you have heart disease or take certain heart medications, you may help shape better care for yourself and others.
Cornwall, OntarioAges 40 years+ - NCT07356843Recruiting
Palliative Care for Heart Failure Patients
This study looks at how to improve palliative care for people with heart failure. It involves healthcare workers who care for heart failure patients and will help find better ways to support them.
Indianapolis, IndianaAges 18 years+ - NCT07360925Recruiting
Fat around heart arteries in transplant patients
This study looks at a type of fat around the heart's arteries in people who need a heart transplant. It may help doctors understand how fat affects heart disease.
PragueAges 30–90 - NCT07369856Recruiting
Using urine sodium to guide diuretic dosing in heart failure
This trial uses a simple urine test to see if your current water pill dose is right for you. The goal is to find the best dose to reduce symptoms and avoid hospital visits.
Vancouver, British ColumbiaAges 18 years+ - NCT07373041Recruiting
Support program for heart failure carers in the UK
This study tests a support program for people who care for loved ones with heart failure. It aims to see if the program helps carers by providing talking support and information, and it may help you if you’re caring for someone with heart failure and are comfortable using a digital device.
BelfastAges 18 years+ - NCT00762008Recruiting
Test blood markers to understand progression to heart failure
This study looks at blood “markers” (substances in the blood) to help explain how some people move from early heart strain to full heart failure. You may be enrolled if you have stable or worsening heart failure symptoms, or you may qualify as a healthy control for comparison.
Farmington, ConnecticutAges 18 years+ - NCT02368041Recruiting
Near-infrared scan test in children with heart failure
This study tests whether a near-infrared “light scan” on the hand can help doctors in children with heart failure who are stable on their usual medications. It may give additional information about blood flow and circulation in the body without using invasive procedures.
Gainesville, FloridaAges Up to 25 years - NCT02693509Recruiting
Hospitalized heart failure patients can join a heart study registry
This study collects information from people who are hospitalized for congestive heart failure. It helps researchers understand how heart failure is treated in real-world care and may improve future guidelines.
Dallas, TexasAges 18–125 - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Gilbert, ArizonaAges 18 years+ - NCT03180320Recruiting
Exercise program for chronic heart failure with confidence building
This trial studies whether a specific gentle exercise routine (Baduanjin, “eight-silken-movement”) plus skills to build self-confidence can help people with chronic heart failure. It’s meant for people who are stable and can do prescribed exercise testing and sessions.
Guangzhou, GuangdongAges 18 years+ - NCT02814942Recruiting
Testing CRT in people with weak hearts and wide ECG signals
This study looks at whether a device called CRT (Cardiac Resynchronization Therapy) can help people with heart failure who have a weak heart pumping strength and a “wide” electrical signal pattern on an ECG. It may help some people feel better and improve heart function, especially if they are not already on the best standard medicines.
SingaporeAges 18 years+ - NCT07405944RecruitingPhase 4
Vericiguat and heart function in heart failure patients
This trial tests whether vericiguat can improve heart function in people with stable heart failure and a reduced pumping ability. It may help if you have not needed hospital or IV treatments for worsening heart failure in the last 6 months.
LjubljanaAges 18 years+ - NCT07419360Recruiting
Draining fluid from lungs in heart failure
This study tests whether draining fluid from around the lungs can help people with heart failure who are in the hospital. It looks at how this procedure affects breathing and recovery.
Albany, New YorkAges 18 years+ - NCT07430553Recruiting
Comparing pacemakers for better heart function in heart failure
This trial compares three types of advanced pacemakers (cardiac resynchronization therapy devices) to see which works best for improving heart function and reducing abnormal heart rhythms in people with heart failure.
London, Greater LondonAges 18 years+ - NCT07442903Recruiting
Tricuspid valve repair with remote pressure monitoring
This trial tests a new way to closely monitor heart function during tricuspid valve repair or replacement. A tiny sensor is placed in your lung artery to track pressure, helping doctors adjust your care remotely.
MunichAges 18 years+ - NCT07443670Recruiting
Voice analysis for heart failure monitoring
This trial tests whether analyzing your voice recordings (taken daily) can detect changes in lung artery pressure. It could help monitor heart failure without extra clinic visits.
San Francisco, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 981 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.