Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06819618Recruiting
Predicting heart failure outcomes with machine learning
This trial uses machine learning to analyze data from a smartwatch to predict how heart failure progresses. It may help doctors better understand your condition and tailor treatments.
Goettigen, Lower SaxonyAges 18 years+ - NCT06826963Recruiting
Eccentric exercise for older adults with heart failure and muscle loss
This study tests whether a special type of exercise (eccentric, or lengthening, exercises) can help older adults with heart failure who also have muscle loss. It aims to see if the exercise is safe and improves strength and function.
Verona, VeronaAges 65–85 - NCT06831825RecruitingPhase 1
Gene therapy for heart failure recovery trial
This trial tests a gene therapy injected into the heart to help it recover after a previous heart attack. It may be an option for people with stable heart failure who are not eligible for standard procedures like stents or bypass surgery.
Houston, TexasAges 18–79 - NCT06851949RecruitingPhase 2
Vsling device for ventricular repair in heart failure
This trial tests a new device called Vsling, which is placed inside the heart to help reshape the main pumping chamber (left ventricle) in people with heart failure. It may improve your heart's strength and reduce symptoms like shortness of breath.
Be’er Ya‘aqovAges 18 years+ - NCT06868797Recruiting
Dapagliflozin for advanced heart failure patients waiting for transplant
This study tests whether dapagliflozin (a medicine already approved for other heart conditions) can help protect kidney and heart function in people with very advanced heart failure who are waiting for a heart transplant. If you qualify, you'll help researchers learn if this drug offers extra benefits beyond standard care.
BronAges 18 years+ - NCT06884631Recruiting
Heart failure risk assessment with exercise test and kidney health
This study uses a special exercise test, along with heart and kidney measurements, to better predict risks for people with heart failure. It may help your doctors understand your condition and choose the best care for you.
Milan, ItalyAges 18 years+ - NCT06885164Recruiting
Remote heart monitoring for heart failure patients
This trial tests whether remote monitoring of heart function can help manage heart failure. It may be an option if you have symptoms like shortness of breath or fatigue (NYHA class II or higher) and are between 18 and 90 years old.
Aalborg, DenmarkAges 18–90 - NCT06895070Recruiting
Heart transplant study using a special preservation machine
This trial tests a special machine that preserves donor hearts for longer periods before transplant. It may help people waiting for a heart transplant who need a heart from a donor that may be older or has some heart risks.
La Jolla, CaliforniaAges 18 years+ - NCT06909682Recruiting
AI monitoring with wearables for chronic heart failure
This trial tests an AI system that uses wearable devices and mini-invasive tools to monitor people with chronic heart failure. The goal is to detect changes early and help manage the condition at home.
SalernoAges 19 years+ - NCT06915584Recruiting
Drug management study for heart failure
This study looks at how medications are managed in people with heart failure, especially those who have been in the hospital recently for worsening symptoms. It aims to improve treatment strategies.
Rome, RMAges 18 years+ - NCT06939985Recruiting
Heart health and metabolism registry for heart failure
This trial is a registry that will follow people with different types of chronic heart failure to better understand how heart health and metabolism are linked. It may help doctors improve care for future patients.
ShanghaiAges 18 years+ - NCT06961929Recruiting
Heat and Heart Failure Study
This study looks at how heat affects the body in people with stable heart failure compared to healthy volunteers. It may help researchers understand how to better manage heart failure in daily life.
Dallas, TexasAges 45 years+ - NCT06969560Recruiting
Wearable monitor for heart failure in kids
This study tests a wearable patch (like a smart bandage) that tracks your heart health at home. It's for children and teens with heart failure to help doctors monitor them without frequent hospital visits.
Edmonton, AlbertaAges 8–18 - NCT06979726RecruitingPhase 4
Lasix under the skin for heart failure symptoms
This study tests a way to give a common water pill (called Lasix, or furosemide) under the skin using a small pump at home, instead of in the hospital. It may help people with heart failure who have fluid buildup that isn't getting better with oral water pills.
Gainesville, FloridaAges 18–80 - NCT06989580Recruiting
Heart failure monitoring with a wireless implant
This trial is testing a special monitor (BIOMONITOR) that tracks your heart function and sends data wirelessly to your doctor. It aims to help manage heart failure by catching early signs of trouble so you can get treatment sooner.
GenkAges 18 years+ - NCT06993220Recruiting
Reducing fluid buildup in heart failure patients at discharge
This trial is for people hospitalized with heart failure and signs of fluid overload, such as swelling or fluid in the lungs. It aims to check if patients still have extra fluid when they go home, which may help improve their recovery.
Sant Joan Despí, BarcelonaAges 18 years+ - NCT07008365RecruitingPhase 3
Measuring belly pressure and ultrasound to guide fluid removal in heart failure
This trial tests whether using belly pressure and bedside ultrasound can help doctors better manage fluid removal (decongestion) in people hospitalized with heart failure. The goal is to see if this approach leads to better outcomes.
ZaragozaAges 18–100 - NCT07023536Recruiting
Heart rehab program from home for chronic heart failure
This trial tests a cardiac telerehabilitation program for people with chronic heart failure. It is designed to see if doing rehab at home using digital tools helps improve health and quality of life.
SalernoAges 18 years+ - NCT07094737Recruiting
Heart rehab study for coronary disease or heart failure
This study tracks how well heart rehabilitation works for people with coronary artery disease or heart failure. It aims to improve future care by learning from your experience.
MilanAges 18 years+ - NCT07154758Recruiting
Optimizing heart failure treatment using registry data
This trial uses a national heart failure registry to see if a new way of monitoring treatment can help optimize therapy for people with heart failure and reduced ejection fraction (a weak heart pump). It may lead to better medication adjustments over time.
GothenburgAges Any age - NCT07173426Recruiting
Using bioimpedance to guide fluid therapy in heart failure
This study tests a new way to manage fluid buildup in patients hospitalized with worsening heart failure. It uses a simple, non-invasive tool (‘bioimpedance’) to help doctors better balance your fluids, which could help you feel better and recover faster.
Basildon, EssexAges 18 years+ - NCT07185100Recruiting
Finding early heart failure in at-risk adults across Germany
This study uses heart MRI scans to find unrecognized heart failure in people who have risk factors like diabetes, kidney disease, high blood pressure, or obesity but haven't been diagnosed with heart failure yet. If you join, you will help researchers learn how common hidden heart failure is and take an important step for your own heart health.
BerlinAges 40–69 - NCT07192341Recruiting
Heart failure drug for people with artificial heart valves
This trial tests a drug called sacubitril/valsartan to see if it helps people who have both a prosthetic heart valve and heart failure with a weak heart pump. The goal is to improve heart function and symptoms.
Kafr ash Shaykh, KafrelsheikhAges 18 years+ - NCT07199088Recruiting
Comparing two medicines for fluid buildup in heart failure
This study tests whether adding acetazolamide or metolazone to standard treatment helps remove extra fluid better in people hospitalized for heart failure. It aims to find a safer and more effective option for managing fluid overload.
Chak Four Hundred Fifty-four, Punjab ProvinceAges 18 years+
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 981 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.