Clinical trials
High-flow Nasal Cannula clinical trials
Below are recruiting high-flow nasal cannula clinical trials, each written for real people, not researchers. We’re tracking 20 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05691218Recruiting
Early high-flow oxygen plus nebulized asthma medicine
This study tests whether giving fast, high-flow oxygen early—together with inhaled terbutaline via a vibrating mist—helps adults with moderate to severe asthma flare-ups in the emergency department. It aims to see if this approach improves breathing after initial treatment.
Poitiers, FranceAges 18 years+ - NCT05967507Recruiting
Testing oxygen flow during infant airway tube placement
This trial studies how different oxygen flow rates affect breathing during the process of placing a breathing tube in babies. It may help clinicians choose safer oxygen settings during routine and urgent (but not life-threatening) airway management.
Philadelphia, PennsylvaniaAges Up to 12 months - NCT05526534Recruiting
Breathing treatment to prevent lung problems after gynecologic surgery
This trial studies whether a breathing support therapy given after surgery can reduce the chance of lung complications. It focuses on people having gynecologic tumor surgery who are at higher risk for breathing or lung problems.
Chengdu, SichuanAges 18–90 - NCT06425406Recruiting
Preventing low oxygen in children during anesthesia with HFNC
This trial tests whether a special oxygen device (HFNC) can prevent low oxygen levels in children during anesthesia. It is for children aged 2-10 who are generally healthy and having surgery.
Zhengzhou, HenanAges 2–10 - NCT07007715Recruiting
Finding the best oxygen flow setting after extubation
This trial tests different flow rates for a high-flow nasal cannula (a device that delivers warm, moist oxygen) after a breathing tube is removed. It aims to find the best setting for patients moving from a ventilator to breathing on their own.
TaipeiAges 18 years+ - NCT06879600Recruiting
High-flow oxygen for emergency surgery patients with full stomachs
This trial tests if using high-flow oxygen through the nose before surgery helps patients who need emergency surgery and have a full stomach. It may make oxygen levels safer during the start of anesthesia.
Viet Tri, Phu ThoAges 18 years+ - NCT07611903Recruiting
Oxygen delivery methods during endoscopy procedure
This trial compares two different ways of delivering oxygen through your nose during an endoscopy procedure (ERCP, which examines your bile ducts and pancreas). The study tests whether one method keeps your oxygen levels safer or more comfortable than the other.
Kocaeli, UmuttepeAges 18–84 - NCT07384494Recruiting
High-flow oxygen vs regular oxygen for awake intubation with difficult airways
This trial compares two ways of giving oxygen during a procedure where you are awake but have a tube placed in your windpipe. It may help patients with airways that are hard to open safely.
Wuwei, GansuAges 18 years+ - NCT05011877Recruiting
Study for sleep testing after sudden breathing trouble
This trial studies people who unexpectedly end up in the hospital or emergency room because of a sudden worsening in breathing that leads to too much carbon dioxide. It may help doctors understand whether sleep-related breathing issues contribute and how to better prevent repeat episodes.
Toronto, OntarioAges 18 years+ - NCT05883137Recruiting
High-flow nasal oxygen during intubation in the ICU
This trial looks at using a special, fast-flow oxygen device through the nose during intubation in critically ill adults. It may help keep oxygen levels safer while a breathing tube is placed.
Stockholm, Stockholm CountyAges 18–100 - NCT06671015Recruiting
Comparing breathing support methods after a breathing tube is removed in people with heart failure
This study compares two types of breathing support—a high-flow nasal cannula and noninvasive ventilation—to see which one better prevents the need for re-inserting a breathing tube in people with systolic heart failure who are at high risk for breathing problems after the tube is removed.
New Haven, ConnecticutAges 18 years+ - NCT06795971Recruiting
Comparing oxygen methods for hypoxemic respiratory failure
This trial compares three ways of giving extra oxygen to people with low blood oxygen levels: a face mask with continuous pressure, a noninvasive ventilator, or high-flow oxygen through the nose. The goal is to see which method helps people avoid needing a breathing tube.
Nanjing, JiangsuAges 18 years+ - NCT07059689Recruiting
Comparing breathing support after heart surgery in children
This trial compares two types of breathing support (high-flow nasal cannula vs. non-invasive ventilation) in children who have recently had heart surgery and are at high risk of having trouble breathing after their breathing tube is removed. The goal is to see which method works better to help them breathe on their own.
Jakarta, DKI JakartaAges Up to 18 years - NCT07175155Recruiting
Breathing device and oxygen for endoscopy in severe obesity
This study tests a special breathing device (a tube placed in the throat) combined with high-flow oxygen through the nose during sedation for endoscopy in people with severe obesity. It aims to see if this combination helps keep oxygen levels stable and makes the procedure safer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07307560Recruiting
High-flow oxygen during sedation for sleep apnea patients having endoscopy
This study tests if high-flow nasal oxygen can prevent oxygen drops during sedated endoscopy in patients with severe obstructive sleep apnea. It may help people who are at higher risk of breathing problems during the procedure.
Hangzhou, ZhejiangAges 18 years+ - NCT07518862Recruiting
Using heart rate to guide oxygen therapy settings
This study uses a simple, non-invasive test (heart rate monitoring) to help doctors adjust the flow of oxygen therapy through a nasal cannula. It may help improve how well this breathing support works for you.
Toronto, OntarioAges 18 years+ - NCT07536477Recruiting
High-flow oxygen versus standard oxygen for altitude lung swelling
This trial tests whether high-flow oxygen (delivered through a special nasal tube) works better than standard oxygen therapy for a condition called high-altitude pulmonary edema (HAPE)—fluid buildup in the lungs caused by rapid ascent to high altitude. The study aims to see which approach helps patients breathe better and recover faster.
Xigazê, TibetAges 18 years+ - NCT07607080Recruiting
Predicting Treatment Success for High-Flow Oxygen Support
This study helps doctors predict which patients receiving high-flow oxygen through a nasal tube will need additional breathing support. Researchers use blood tests and clinical information to identify who might need a ventilator, allowing earlier interventions if needed.
Barcelona, CataloniaAges 18 years+ - NCT06970990Recruiting
Testing nose pressure to measure breathing effort with oxygen therapy
This trial uses a small tube in your nose to measure how hard you are working to breathe while receiving different types of oxygen therapy. It aims to find out if this nose pressure test can replace a more invasive test, making monitoring easier for you.
Beijing, Beijing MunicipalityAges 18 years+ - NCT03976180Recruiting
High-flow oxygen for painful sickle cell episodes
This trial tests whether giving high-flow oxygen can help treat a painful sickle cell “vaso-occlusive crisis” (VOC) and lower the risk of a serious lung complication. You may be eligible if you’re an adult with sickle cell disease experiencing an opioid-requiring pain flare and have higher risk for lung trouble.
CréteilAges 18 years+
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Common questions
- Are there clinical trials for high-flow nasal cannula?
- Yes. Clin2 currently lists 20 recruiting high-flow nasal cannula studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high-flow nasal cannula trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high-flow nasal cannula trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.