Clinical trials · Michigan
High blood pressure clinical trials in Michigan
We’re tracking 33 recruiting high blood pressure studies with a site in Michigan — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Michigan
- NCT07511361RecruitingPhase 2
Tonlamarsen for high blood pressure after hospitalization
This study tests an investigational medication (Tonlamarsen) for people who were recently hospitalized for a very severe high blood pressure episode and also have heart or kidney disease. It aims to see if the drug can help control blood pressure after discharge.
Detroit, MichiganAges 18 years+ - NCT04071327Recruiting
Pulmonary hypertension registry for patient experiences
This trial is a registry that collects health information from people with pulmonary hypertension to better understand the disease and improve care. You may be asked to share details about your diagnosis and visits, especially soon after you start seeing a specialized PH care center.
Detroit, MichiganAges birth+ - NCT03683186Enrolling by invitationPhase 3
Long-term study of ralinepag for pulmonary hypertension
This study follows people with pulmonary arterial hypertension (PAH) to see how safe and effective ralinepag is over the long term. It may help your care team understand what to expect from continued treatment and monitoring.
Grand Rapids, MichiganAges 18 years+ - NCT07175038RecruitingPhase 2
Study of a new pill for pulmonary hypertension
This study tests a new pill, ROC-101, for people with pulmonary hypertension (high blood pressure in the lungs). It aims to see if the pill can improve symptoms and daily function.
Ann Arbor, MichiganAges 18–80 - NCT07214376Recruiting
Nerve ablation for pulmonary hypertension from left heart disease
This trial tests a device that uses a catheter to deliver energy to nerves around the pulmonary arteries, aiming to reduce high blood pressure in the lungs caused by left heart failure. It is for people with ongoing heart failure symptoms despite optimal medications.
Detroit, MichiganAges 18–85 - NCT06785116RecruitingPhase 4
Study on dapagliflozin for heart health after a hypertensive pregnancy
This trial tests a medicine called dapagliflozin (DAPA) to see if it reduces heart risk in women who had high blood pressure or preeclampsia during pregnancy. It is designed for those who had severe blood pressure rises around delivery or a high BNP level, a marker of heart strain.
Ann Arbor, MichiganAges 18 years+ - NCT06388421Recruiting
PH-ILD patient registry: tracking real-world outcomes
This study tracks people with both lung scarring and high blood pressure in the lungs (Group 3 PH-ILD) to better understand the disease and how treatments like Tyvaso work in real life. It may help you and your doctor make more informed decisions about your care.
Troy, MichiganAges 18 years+ - NCT06059638Recruiting
Pacemaker pacing for blood pressure control
This study tests whether adjusting the timing of a pacemaker can help lower blood pressure in people who already have or need a pacemaker. It could be an option for those whose blood pressure is not well controlled with medication.
Detroit, MichiganAges 18 years+ - NCT07181109RecruitingPhase 3
Study of zilebesiran for high-risk hypertension patients
This trial tests a new medicine called zilebesiran for people with high blood pressure that isn't well controlled. It may be an option if you have heart or blood vessel disease, or are at high risk for it.
Flint, MichiganAges 18 years+ - NCT07543120RecruitingPhase 2
Extended Safety Study of QCZ484 Blood Pressure Medication
This is a continuation study for people who completed a previous QCZ484 trial and tolerated it well. Researchers will monitor how safe and effective the medication remains with longer-term use for managing high blood pressure.
Troy, MichiganAges 18 years+ - NCT07473700RecruitingPhase 2
Study of TX000045 for lung scarring and high blood pressure in the lungs
This trial tests a new medicine called TX000045 for people who have both lung scarring (interstitial lung disease) and high blood pressure in the lungs (pulmonary hypertension). It aims to see if the drug can help improve breathing and daily function.
Allen Park, MichiganAges 18–80 - NCT06911632Recruiting
AI-assisted check for pulmonary hypertension in interstitial lung disease
This study uses an AI tool to help doctors decide if you should be tested for pulmonary hypertension (high blood pressure in the lungs), which can be a complication of interstitial lung disease. If the tool suggests you might have it, you may get an echocardiogram (an ultrasound of the heart) and a right heart catheterization (a test to measure pressure in the heart) to find out for sure.
Ann Arbor, MichiganAges 18 years+ - NCT06559891Recruiting
Ultrasound treatment for high blood pressure
This trial tests an ultrasound device that targets nerves around the kidney to lower blood pressure. It may help people whose blood pressure is not well controlled with medication.
Southfield, MichiganAges 22–75 - NCT06526858Recruiting
Laparoscopic kidney nerve treatment for resistant hypertension
This study tests a new treatment called HyperQure RDN, a laparoscopic (keyhole) surgery that targets nerves near the kidneys to lower blood pressure in people with resistant hypertension. If you have tried multiple medications but your blood pressure is still high, this procedure might offer an alternative approach.
Detroit, MichiganAges 22–80 - NCT06391073Recruiting
Testing a text program for high blood pressure after the ER
This study tests a text-message program to help people with high blood pressure manage their health after leaving the emergency department. If you qualify, you'll get tips and reminders on your phone to keep your blood pressure under control.
Flint, MichiganAges 18–99 - NCT06343298RecruitingPhase 2
Study of manp for hard-to-control high blood pressure
This study tests a new investigational drug called MANP to see if it can lower blood pressure in people whose blood pressure stays high even when they are already taking several medications. If it works, this drug might offer a new option for people with difficult-to-control hypertension.
Dearborn, MichiganAges 18–80 - NCT06297291Recruiting
Blood pressure study after kidney nerve treatment
This study looks at how well a procedure that uses sound waves to calm kidney nerves (renal denervation) lowers blood pressure over time. It may help people whose blood pressure stays high despite taking medication.
Detroit, MichiganAges 18 years+ - NCT07783802RecruitingPhase 2
Study of clazakizumab for adults with high inflammation and heart risk
This study tests whether clazakizumab can reduce the risk of heart attacks or strokes in people with high levels of inflammation (measured by a blood test called hsCRP) and conditions like heart disease, obesity, diabetes, high blood pressure, or kidney disease. If you qualify, you'll receive either the study drug or a placebo to see if it helps lower your risk.
Dearborn, MichiganAges 18 years+ - NCT07333183RecruitingPhase 2
Mosliciguat plus treprostinil for lung disease with pulmonary hypertension
This trial tests a new medicine called mosliciguat combined with an inhaled treatment (treprostinil) for people who have both scarring lung disease (interstitial lung disease) and high blood pressure in the lungs. It aims to see if this combination can improve how well you feel and function.
Ann Arbor, MichiganAges 18–85 - NCT07231757Recruiting
Blood pressure study for older adults
This study tests a treatment to lower blood pressure in adults aged 65 and older whose blood pressure is not well controlled with their current medications. It may be an option for those looking for additional ways to manage their hypertension.
Detroit, MichiganAges 65 years+ - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Dearborn, MichiganAges 18 years+ - NCT06907147Recruiting
Renal denervation for uncontrolled high blood pressure
This trial tests a procedure called renal denervation to lower blood pressure in people whose medication isn't enough. It uses a special catheter to calm nerves near the kidneys that may be overactive.
Southfield, MichiganAges 18–80 - NCT06823115Enrolling by invitation
Worldwide study of kidney injury in newborns
This study looks at how common acute kidney injury is in newborns in the intensive care unit. It helps doctors understand which babies are at risk and how to prevent kidney problems.
Ann Arbor, MichiganAges birth–2 weeks - NCT06593496Recruiting
Heart health study for mobile clinic patients
This study looks at how to improve heart and metabolic health in people with early signs of high blood pressure. Participants receive text messages and are followed over time through their medical records.
Detroit, MichiganAges 18 years+
High blood pressure trials by city in Michigan
Where these studies are running in Michigan
Institutions with a site for the recruiting high blood pressure studies listed above.
- Henry Ford Health · 7 studies
- Revival Research Institute, LLC · 3 studies
- University of Michigan · 3 studies
- Ascension St. John Hospital · 2 studies
- Henry Ford Providence Hospital · 2 studies
- AA Medical Research Center
- Aa Mrc Llc
- Allen Park
What taking part in a high blood pressure study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
High blood pressure trials in other states
Common questions
- Are there high blood pressure clinical trials in Michigan?
- Yes. We're currently tracking 33 recruiting high blood pressure studies with a site in Michigan, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a high blood pressure study in Michigan?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Michigan to take part?
- Not necessarily. These studies have a site in Michigan, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New high blood pressure studies open in Michigan regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.