Clinical trials
Intensity-modulated Radiotherapy clinical trials
Below are recruiting intensity-modulated radiotherapy clinical trials, each written for real people, not researchers. We’re tracking 58 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06516133RecruitingPhase 3
Online adaptive radiotherapy for nasopharyngeal cancer
This trial tests a new type of radiation therapy that adjusts in real-time to treat nasopharyngeal cancer. It is for people who have not received prior radiation and have no distant spread of cancer.
Guangzhou, GuangdongAges 18–70 - NCT06529562Recruiting
Surgery plus reduced chemo and radiation vs standard for nasopharyngeal cancer
This trial compares two approaches for people with early-stage nasopharyngeal cancer that can be removed with surgery. It tests whether giving less intense chemotherapy and radiation after surgery works as well as a standard dose, with fewer side effects.
Zhuhai, GuangdongAges 18–70 - NCT06533267Recruiting
Endoscopic surgery vs. radiation for early-stage nasal cancer
This trial compares two treatments for stage I nasopharyngeal cancer (a type of nasal cancer). It tests whether a minimally invasive surgery (endoscopic surgery) is as good as or better than radiation therapy. It may be an option for people whose cancer is small and hasn't spread to lymph nodes.
Zhuhai, GuangdongAges 18–75 - NCT06749899RecruitingPhase 3
Immunotherapy with chemoradiation for advanced nasopharyngeal cancer
This trial tests a combination of a new immunotherapy (QL1706) plus standard chemoradiation for people with advanced nasopharyngeal cancer that hasn't spread to distant organs. The goal is to see if adding this drug helps control the cancer better than standard treatment alone.
Fuzhou, FujianAges 18–65 - NCT06914999RecruitingEarly Phase 1
Comparing a new scan to standard scan during head and neck cancer radiation
This trial is testing whether a newer type of PET/CT scan (F-18 NaF) can better detect blood vessel problems caused by radiation therapy than the standard scan (F-18 FDG) in people with head and neck cancer. If successful, it could lead to better ways to prevent and manage these complications.
Atlanta, GeorgiaAges 18 years+ - NCT07000643RecruitingPhase 3
Proton vs. standard radiation for nasopharyngeal cancer
This trial compares two types of radiation therapy—proton beam versus standard X-ray (photon)—for treating nasopharyngeal cancer. The goal is to see if proton therapy works as well as standard therapy while possibly causing fewer side effects.
JinanAges 18–75 - NCT07338526Recruiting
Proton therapy for children with brain tumors
This trial tests if a precise type of radiation called proton therapy is safe and effective for children with certain brain tumors. It aims to reduce side effects by focusing radiation only on the tumor.
Mumbai, MaharashtraAges 6–16 - NCT07340515RecruitingPhase 3
Proton vs standard radiation for advanced nasopharyngeal cancer
This trial is testing whether a newer, more precise type of radiation (proton therapy) works better than standard radiation (IMRT) for people with advanced nasopharyngeal cancer. It also includes chemotherapy and immunotherapy to see if the combination can improve outcomes.
Jinan, ShandongAges 18–70 - NCT07439497RecruitingPhase 2
Shorter radiation with chemo for cervical cancer
This trial tests a shorter course of high-precision radiation therapy given at the same time as chemotherapy for cervical cancer that has not spread to distant organs. It aims to find if this approach is effective and safe for patients with locally advanced disease.
Seoul, Gangnam-guAges 20 years+ - NCT07459296RecruitingPhase 3
Becotatug vedotin plus sintilimab for advanced nasopharyngeal cancer
This trial tests a combination of two drugs, becotatug vedotin and sintilimab, for patients with a type of nasopharyngeal cancer that has spread to nearby lymph nodes but not to distant organs. It aims to see if this treatment can help control the disease.
Nanning, GuangxiAges 18–70 - NCT07481786RecruitingPhase 3
Bevacizumab with focused radiation vs standard brain radiation for lung cancer with brain spread
This trial tests combining a drug called bevacizumab with a focused radiation treatment for people with lung cancer that has spread to the brain. It compares this to the standard radiation approach, and aims to see which better preserves memory and controls tumors.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06890871Enrolling by invitationPhase 1/Phase 2
Radiation with immunotherapy and anti-angiogenic therapy for advanced HER2-negative breast cancer
This trial tests a combination of radiation therapy, immunotherapy, and a drug that blocks blood vessel growth for advanced HER2-negative breast cancer that has spread. It is for patients whose cancer has worsened after at least two prior treatments.
Wuhan, HubeiAges 18–75 - NCT06250972RecruitingPhase 3
Radiotherapy for advanced pancreatic cancer with normal CA19-9 after chemo
This trial tests whether giving radiotherapy to the pancreas can help people with advanced pancreatic cancer whose CA19-9 level has dropped to normal after chemotherapy. It's for patients whose cancer is still locally advanced (hasn't spread to distant organs).
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06507683Recruiting
Radiation plus ripretinib for advanced GIST
This trial tests whether adding radiation therapy to the drug ripretinib can help people with advanced gastrointestinal stromal tumors (GIST) that can't be removed by surgery and have stopped responding to other treatments. It aims to see if this combination is safe and effective.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06971211RecruitingPhase 2
Radiation and drug combo for advanced prostate cancer
This trial combines radiation therapy with two drugs (fluzopanib and abiraterone acetate) to treat men with metastatic castration-resistant prostate cancer that hasn't been treated yet. The goal is to see if this triple approach helps slow the cancer's growth.
Shenyang, LiaoningAges 18 years+ - NCT05412082RecruitingPhase 1
Smart chemo and radiation plan for locally advanced rectal cancer
This Phase 1 study tests a “smart” total treatment plan using chemotherapy (chemo) and radiation before surgery for people with locally advanced rectal cancer. The goal is to see if this approach is safe and can work well while helping plan treatment based on your situation.
Miami, FloridaAges 18 years+ - NCT03801876RecruitingPhase 3
Proton versus photon radiation for esophageal cancer
This trial compares proton therapy and standard photon (X-ray) radiation for treating esophageal cancer. It looks to see which approach works better and is safer for people who need chemoradiation.
Phoenix, ArizonaAges 18 years+ - NCT06327477RecruitingPhase 1/Phase 2
A new type of radiation for newly diagnosed retroperitoneal sarcoma
This trial tests a new way of giving radiation called proton spatially fractionated radiotherapy (P-SFRT) combined with standard radiation for people with a type of sarcoma in the back of the belly. The goal is to see if this combination can treat the tumor more effectively.
Chicago, IllinoisAges 18 years+ - NCT05600842Recruiting
Lower-dose radiation for HPV-positive throat cancer
This trial tests whether using a de-escalated (lower/intensity-reduced) radiation approach can treat HPV-positive oropharyngeal squamous cell carcinoma. It may help reduce side effects while still keeping the cancer under control.
Orange, CaliforniaAges 18 years+ - NCT07293247RecruitingPhase 2
Targeted radiation after lung cancer surgery
This trial tests if targeted radiation after surgery can help people with non-small cell lung cancer who still have cancer in their lymph nodes after chemotherapy. Participants will have had surgery and chemotherapy before starting radiation.
Jonesboro, ArkansasAges 18 years+ - NCT03180268RecruitingPhase 3
Watch or radiate after surgery for grade II meningioma
This trial studies whether people with a grade II meningioma that has been completely removed by surgery should be monitored only or treated with radiation. It may help reduce the risk of the tumor coming back while balancing radiation side effects.
Birmingham, AlabamaAges 18 years+ - NCT03975231RecruitingPhase 1
Targeted drugs and radiation for BRAF-mutated thyroid cancer
This Phase 1 trial studies whether targeted medicines (dabrafenib and trametinib) plus radiation can control an aggressive thyroid cancer with a specific BRAF gene change. It may help by attacking cancer cells that have this mutation and using focused radiation to improve tumor control.
Duarte, CaliforniaAges 18 years+ - NCT04342429Recruiting
Proton radiation study for small cell lung cancer
This study looks at a type of radiation treatment using proton beams (IMPT) for small cell lung cancer. It may help assess whether this approach can safely deliver the planned radiation doses to the chest.
Atlanta, GeorgiaAges 18 years+ - NCT04703101RecruitingPhase 1
Short radiation plus chemo for stage II–III rectal cancer
This trial tests a short course of radiation therapy combined with chemotherapy for people with stage II or III rectal cancer. It’s designed to see whether this approach is safe and effective before or around cancer surgery.
Los Angeles, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for intensity-modulated radiotherapy?
- Yes. Clin2 currently lists 58 recruiting intensity-modulated radiotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intensity-modulated radiotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intensity-modulated radiotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.