Clinical trials
Mechanical Ventilation clinical trials
Below are recruiting mechanical ventilation clinical trials, each written for real people, not researchers. We’re tracking 266 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07614555Recruiting
Breathing methods during back surgery recovery
This study compares two ways doctors control your breathing during lumbar disc herniation (slipped disc) surgery. Researchers want to see which method keeps your lungs healthier during the operation.
AnkaraAges 18–65 - NCT07519512Recruiting
Early Switch to Assisted Breathing in ICU Patients
This study tests whether moving ICU patients from fully machine-controlled breathing to partially assisted breathing earlier helps them get off ventilators successfully. The goal is to see if this approach reduces the time patients need mechanical ventilation.
Nanjing, JiangsuAges 18 years+ - NCT07193719RecruitingPhase 1/Phase 2
Personalized breathing support for kids after heart surgery
This study tests a personalized breathing technique to improve lung function and heart performance in children who have had heart surgery or are on ECMO. The goal is to find the best way to open up the lungs safely.
BerlinAges birth–18 years - NCT06531005Recruiting
Checking breathing to predict when a breathing tube can be removed in the ICU
This study looks at how well current breathing measures predict a patient's readiness to have their breathing tube removed in the intensive care unit (ICU). It aims to make the decision to remove the tube safer and more accurate.
Altindağ, AnkaraAges 18 years+ - NCT07325812Recruiting
Lung opening maneuvers during spine surgery
This study tests whether periodic lung opening maneuvers during back surgery can reduce lung collapse and improve breathing mechanics. Doctors will use ultrasound to monitor your lungs.
IstanbulAges 18–65 - NCT06837402Enrolling by invitation
Non-invasive ventilation in Argentine ICUs: an observational study
This study looks at how non-invasive breathing support (like a mask or machine) is used in ICUs across Argentina. It helps doctors understand patterns of care so they can improve treatment for patients with breathing problems.
CABA, Buenos AiresAges 18 years+ - NCT06430554Recruiting
Personalized ventilation for ARDS patients on breathing machines
This trial tests a personalized ventilation method that adjusts how the breathing machine delivers air based on your lung's air and blood flow match. It aims to improve breathing for people with moderate to severe ARDS who are already on a ventilator and will be placed on their stomach.
Nanjing, JiangsuAges 18–85 - NCT07325773Recruiting
Can magnesium help lung function during one-lung breathing?
This trial tests if giving magnesium during surgery helps oxygen levels in the blood and supports lung mechanics when only one lung is used for breathing.
IstanbulAges 18–80 - NCT07114289Recruiting
Breathing test methods for overweight patients on ventilators
This study compares two ways of testing if overweight or obese patients can breathe on their own after being on a ventilator. You will be randomly assigned to one of two breathing trials (pressure support or a T-piece) to see which works better for helping you get off the ventilator.
TaipeiAges 18 years+ - NCT07207772Recruiting
Electric lung imaging vs. standard breathing support in weight-loss surgery
This study compares two ways of setting the breathing machine during weight-loss surgery: one guided by electrical impedance tomography (EIT) and the other by standard care. The goal is to see which one helps your lungs work better during and after surgery.
Jinan, ShandongAges 18–65 - NCT05030337Recruiting
Closed-loop oxygen control for very preterm babies on ventilators
This trial tests a computer-guided (“closed-loop”) oxygen control system for very preterm babies who need breathing support. It aims to keep oxygen levels safer and more consistent than standard care.
LondonAges Any age - NCT07379242Recruiting
Lung recruitment test for breathing failure patients on a ventilator
This trial uses a special imaging technique (electrical impedance tomography) to find the best ventilator settings for patients with acute breathing failure. It may help doctors tailor treatment to improve lung function.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05687292Recruiting
Decision tool to shorten breathing machine time in children
This study tests whether a computer “decision support” tool can help doctors safely reduce how long a child stays on a breathing machine after heart surgery. It may help children get off mechanical ventilation sooner and recover faster.
Boston, MassachusettsAges 1 day–12 years - NCT06733168Recruiting
Electric imaging to guide breathing machine settings for ARDS
This trial tests whether using a special imaging technique (electrical impedance tomography) to set the breathing machine's pressure can improve oxygen levels and lung function in patients with moderate to severe ARDS, a serious lung condition.
HanoiAges 18 years+ - NCT06819592RecruitingPhase 3
Preventing early lung infections after severe brain injury
This study tests whether giving an antibiotic (ceftriaxone) early after a severe brain injury can prevent lung infections caused by the breathing machine (ventilator). It is for adults in the ICU who recently started on a ventilator due to a brain emergency.
Kingswood, New South WalesAges 18 years+ - NCT05717218Recruiting
Testing special breathing monitoring during VV-ECMO in ARDS
This trial checks whether a special “breathing sensor belt” that watches breathing in real time can be used safely in adults with severe lung failure (ARDS) who are on a machine called VV-ECMO. It may help the care team better monitor ventilation while you’re critically ill.
ParisAges 18 years+ - NCT06816706Recruiting
Comparing two oxygen methods during breathing trials
This study compares two ways of giving oxygen (high-flow through the nose vs. a T-piece) to help patients come off a breathing machine safely. It aims to see which method works better during a test of your ability to breathe on your own.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06673862Enrolling by invitation
Detecting fluid needs with a breathing machine change
This trial checks if a simple change in ventilator settings (a tidal volume challenge) can predict whether you need more fluids, compared to a standard fluid challenge. It's for patients on a breathing machine who have low blood flow.
Banhā, Al-QalyubiaAges 18 years+ - NCT07751237Recruiting
Ultrasound of the diaphragm during breathing machine weaning
This study uses ultrasound to look at how well your diaphragm (the main breathing muscle) is working while you are on a breathing machine. The goal is to see if this can help doctors predict when you can safely breathe on your own and leave the ventilator sooner.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06479655RecruitingPhase 4
Comparing fentanyl and morphine for ICU sedation
This study compares two different pain and sedation medicines (fentanyl and morphine) given continuously through an IV to help patients who are on a breathing machine (ventilator) in the ICU. The goal is to see which medicine works better and is safer for keeping you comfortable and calm.
Kota Bharu, KelantanAges 18 years+ - NCT05506904Recruiting
Help deciding when to remove a breathing tube
This trial studies a decision-support tool that helps ICU teams decide when it’s safe to try removing (extubating) a breathing tube. It may help reduce delays or avoidable re-intubation by guiding the timing of a low-support breathing trial (SBT).
Edmonton, AlbertaAges 18 years+ - NCT06832306Recruiting
Diaphragm pacing for breathing support in ICU
This trial tests a device that helps stimulate the diaphragm to improve breathing in patients who need a ventilator. It's for people with new breathing problems who have been in the ICU on a ventilator for less than 4 days.
La Jolla, CaliforniaAges 18 years+ - NCT07002710Recruiting
Long-term ventilation and inflammation study
This study looks at how long-term inflammation affects the breathing of people who have been on a ventilator for 10 days or more. It aims to help doctors better understand and support your recovery.
TaipeiAges 20 years+ - NCT07066605Recruiting
Dexmedetomidine for agitation during breathing tube removal
This trial tests whether a sedative called dexmedetomidine can reduce agitation in ICU patients when they are being weaned off a breathing tube. If you experience restlessness or agitation during the weaning process, this medication might help you stay calm.
SohagAges 19 years+
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Common questions
- Are there clinical trials for mechanical ventilation?
- Yes. Clin2 currently lists 266 recruiting mechanical ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mechanical ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mechanical ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Mechanical Ventilation Complication
- Mechanical Ventilation Weaning
- Invasive Mechanical Ventilation
- Mechanical Ventilation Pressure High
- Prolonged Mechanical Ventilation
- Weaning Failure of Mechanical Ventilation
- Weaning Invasive Mechanical Ventilation
- Respiratory Insufficiency Requiring Mechanical Ventilation
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.