Clinical trials
Mechanical Ventilation clinical trials
Below are recruiting mechanical ventilation clinical trials, each written for real people, not researchers. We’re tracking 252 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06367218Recruiting
Opioid-free anesthesia with spontaneous breathing for VATS lung nodule surgery
This trial tests a way to do VATS lung nodule surgery without using strong painkillers (opioids) and while you keep breathing on your own. It may help you recover faster with fewer side effects.
Wuhan, HubeiAges 18–70 - NCT06757166Recruiting
Non-invasive respiratory support for COVID-19 breathing failure
This study tests if non-invasive breathing support (like a mask or high-flow oxygen) can help hospitalized patients with low oxygen levels due to COVID-19, without needing a breathing tube. It aims to see how well it works and what risks it may have.
Rotterdam, South HollandAges 18 years+ - NCT06769308Recruiting
Brain wave guided sedation in ICU patients
This study tests a new way to give pain and sedation medicines in the ICU. It uses a special brain wave monitor (EEG) to help doctors adjust your medicines more precisely, aiming to keep you comfortable and safe.
Ferrara, ItalyAges 18–90 - NCT07467551Recruiting
Pain scale study for patients on breathing machines
This study tests a pain scale for patients who are on a breathing machine and cannot speak. It aims to help doctors better recognize pain in these patients.
IstanbulAges 18–85 - NCT07457554Recruiting
Can respiratory quotient help ICU patients on ventilators?
This study looks at whether using a simple measurement called the respiratory quotient (a sign of how your body is using fuel) can help doctors make better decisions for patients on a breathing machine in the ICU. It may lead to safer, more personalized care.
Poznan, WielkopolskaAges 18–85 - NCT07451405Recruiting
Using OLE therapy for lung expansion in ventilated patients with collapsed lungs
This trial tests a breathing treatment called Oscillation and Lung Expansion (OLE) therapy. It is for people on a breathing machine who have a collapsed area in the lung (atelectasis) and a lot of phlegm. The goal is to help open the lungs and clear mucus more easily.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07427121Recruiting
Exercise study for healthy non-smokers on a breathing machine
This study looks at how physical therapy and exercise affect people who are on a breathing machine (mechanical ventilation). It may help researchers find better ways to help patients recover while on a ventilator.
Gainesville, FloridaAges 25–80 - NCT06168162Recruiting
Personalized breathing support during weight-loss surgery
This trial tests whether a personalized breathing setting during surgery can lower the risk of lung complications after weight-loss surgery. If you have a high risk of lung issues, you may be eligible.
Cairo, Cairo GovernorateAges 16 years+ - NCT06829290Recruiting
How muscle loss affects disease course in GI cancers
This study looks at how loss of muscle mass (sarcopenia) affects the course of illness in people with gastrointestinal cancers, liver cirrhosis, or those in the ICU. It will help doctors better understand and treat muscle wasting.
Mainz, Rhineland-PalatinateAges 18 years+ - NCT06716840Recruiting
Remimazolam for sedation after heart surgery
This trial tests a medication called Remimazolam Besylate to sedate patients who need a breathing tube after heart surgery. The goal is to help patients relax while they recover in the intensive care unit.
Hangzhou, ZhejiangAges 18 years+ - NCT06631001Recruiting
Abdominal massage for digestion in ICU patients on tube feeding
This study tests if gentle abdominal massage can improve digestion in intensive care patients who are on a breathing machine and receiving liquid food through a tube. It might help prevent gastrointestinal issues like bloating or slow digestion.
MersinAges 18 years+ - NCT07372664Recruiting
Testing a weaning readiness tool for ventilated patients
This study looks at how well a tool (VVI) can predict if patients on a breathing machine are ready to start breathing on their own. It may help doctors decide the best time to begin the weaning process.
LarissaAges 18 years+ - NCT07377162Recruiting
Hyperoxia effects on brain blood flow in ICU patients
This trial studies how giving extra oxygen (hyperoxia) affects blood flow in the brain for patients on a breathing machine in the intensive care unit. The goal is to see if short bursts of higher oxygen levels are safe and how they change brain activity.
BrusselsAges 18 years+ - NCT06586736Recruiting
Prone position study for ARDS patients
This trial studies how lying face down (prone position) affects breathing in patients with acute respiratory distress syndrome (ARDS). It may help doctors better monitor and treat patients on a breathing machine.
Chengdu, SichuanAges 18–90 - NCT07326215Recruiting
A study of a device that removes carbon dioxide from the blood
This trial tests a device called PrismaLung+ that helps remove extra carbon dioxide from the blood of patients on breathing machines. It may help people whose lungs are struggling despite gentle ventilation settings.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06816706Recruiting
Comparing two oxygen methods during breathing trials
This study compares two ways of giving oxygen (high-flow through the nose vs. a T-piece) to help patients come off a breathing machine safely. It aims to see which method works better during a test of your ability to breathe on your own.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07274527Recruiting
Amnioinfusion for babies exposed to thick meconium during labor
This trial tests whether adding fluid into the womb (amnioinfusion) during labor can protect a baby's lungs and health after being exposed to thick meconium (baby's first poop). It may help reduce breathing problems and improve long-term outcomes.
Milwaukee, WisconsinAges 18 years+ - NCT07265882Recruiting
Bedside test for breathing tube patients
This trial uses a simple bedside test to evaluate patients who are on a breathing machine and not breathing on their own. It may help doctors better understand and manage acute respiratory failure.
Pavia, PaviaAges 18–90 - NCT07256821Recruiting
Finding the best breathing muscle training dose in the ICU
This trial tests different amounts of inspiratory muscle training (IMT) for patients who have a tracheostomy tube and are on a breathing machine in the intensive care unit. Researchers want to find the dose that helps most with recovery.
MarlowAges 18 years+ - NCT07233837Recruiting
Cleaning ICU surfaces with hydrogen peroxide and UV light
This trial tests a new way to clean surfaces in intensive care units (ICUs) using hydrogen peroxide and ultraviolet (UV) light. It aims to see if this method reduces infections in patients.
Barbalha, CearáAges 18 years+ - NCT07233304Recruiting
Lung opening procedure safety in children on breathing machines
This trial tests a lung opening procedure (alveolar recruitment maneuver) in children on a breathing machine to see if it's safe and helpful. It compares how well the procedure works with different machine settings.
Canuelas, Buenos AiresAges 1 month–14 years - NCT07239687Recruiting
Comparing two propofol sedation methods for ICU patients on ventilators
This study compares two computer-controlled methods for delivering propofol sedation to ICU patients on a breathing machine. It aims to determine which method provides safer and more effective sedation for critically ill patients.
AnkaraAges 18 years+ - NCT06911450Recruiting
Ultrasound test for lung strain in ICU patients
This study uses a special ultrasound technique to measure how the lungs stretch (pleural strain) during breathing. It aims to see if this measurement works in ICU patients, both those breathing on their own and those on a ventilator, and how it relates to the pressure needed to inflate the lungs.
Wuhu, AnhuiAges 18–75 - NCT06914336Recruiting
Liver ultrasound to check fluid buildup in ventilated patients
This trial uses an ultrasound of your liver to see if there is extra fluid or pressure in your veins that might make it harder to breathe. It may help doctors understand how to better manage the breathing machine for people who have been on it for more than a day.
BrestAges 18 years+
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Common questions
- Are there clinical trials for mechanical ventilation?
- Yes. Clin2 currently lists 252 recruiting mechanical ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mechanical ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mechanical ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Mechanical Ventilation Complication
- Mechanical Ventilation Weaning
- Invasive Mechanical Ventilation
- Mechanical Ventilation Pressure High
- Prolonged Mechanical Ventilation
- Weaning Failure of Mechanical Ventilation
- Weaning Invasive Mechanical Ventilation
- Respiratory Insufficiency Requiring Mechanical Ventilation
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.