Clinical trials
Mechanical Ventilation clinical trials
Below are recruiting mechanical ventilation clinical trials, each written for real people, not researchers. We’re tracking 266 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07199881Recruiting
Breathing effort study after major abdominal surgery
This study checks how your breathing effort changes with different levels of breathing support from the ventilator after major abdominal surgery. It helps doctors find the best settings to help you breathe comfortably while you recover.
Bangkok, BangkoknoiAges 18 years+ - NCT07559591Recruiting
High-Flow Oxygen to Help Breathing Tube Patients
This study tests whether high-flow oxygen through a breathing tube helps patients recover faster after tracheostomy (a surgical opening in the windpipe). If you're in the ICU with a tracheostomy and nearly ready to breathe on your own, this trial may help you transition off the ventilator more smoothly.
RiyadhAges 18 years+ - NCT07073976Recruiting
Predicting success of coming off the breathing machine using heart ultrasound
This study uses an ultrasound of the heart (echocardiogram) to check how well the right side of your heart is working. The goal is to see if that can help predict whether you will successfully come off the breathing machine.
Istanbul, IstanbulAges 18 years+ - NCT07150637Enrolling by invitation
Predicting muscle weakness in children on a breathing machine
This study aims to predict muscle weakness that can happen to children on breathing machines in the ICU. It could help doctors start treatments earlier to prevent this weakness.
Shanghai, Shanghai MunicipalityAges 1 month–18 years - NCT06757166Recruiting
Non-invasive respiratory support for COVID-19 breathing failure
This study tests if non-invasive breathing support (like a mask or high-flow oxygen) can help hospitalized patients with low oxygen levels due to COVID-19, without needing a breathing tube. It aims to see how well it works and what risks it may have.
Rotterdam, South HollandAges 18 years+ - NCT07427121Recruiting
Exercise study for healthy non-smokers on a breathing machine
This study looks at how physical therapy and exercise affect people who are on a breathing machine (mechanical ventilation). It may help researchers find better ways to help patients recover while on a ventilator.
Gainesville, FloridaAges 25–80 - NCT06903052Recruiting
App for parents managing child's breathing tube symptoms
This trial tests a mobile app that helps parents care for their child who needs a breathing tube at home. The app provides support and tips for managing symptoms, so parents feel more confident and prepared.
Kowloon, KowloonAges 2–18 - NCT07372664Recruiting
Testing a weaning readiness tool for ventilated patients
This study looks at how well a tool (VVI) can predict if patients on a breathing machine are ready to start breathing on their own. It may help doctors decide the best time to begin the weaning process.
LarissaAges 18 years+ - NCT07265882Recruiting
Bedside test for breathing tube patients
This trial uses a simple bedside test to evaluate patients who are on a breathing machine and not breathing on their own. It may help doctors better understand and manage acute respiratory failure.
Pavia, PaviaAges 18–90 - NCT07239687Recruiting
Comparing two propofol sedation methods for ICU patients on ventilators
This study compares two computer-controlled methods for delivering propofol sedation to ICU patients on a breathing machine. It aims to determine which method provides safer and more effective sedation for critically ill patients.
AnkaraAges 18 years+ - NCT06631001Recruiting
Abdominal massage for digestion in ICU patients on tube feeding
This study tests if gentle abdominal massage can improve digestion in intensive care patients who are on a breathing machine and receiving liquid food through a tube. It might help prevent gastrointestinal issues like bloating or slow digestion.
MersinAges 18 years+ - NCT06367218Recruiting
Opioid-free anesthesia with spontaneous breathing for VATS lung nodule surgery
This trial tests a way to do VATS lung nodule surgery without using strong painkillers (opioids) and while you keep breathing on your own. It may help you recover faster with fewer side effects.
Wuhan, HubeiAges 18–70 - NCT06319274RecruitingPhase 2
Prostacyclin for lung infection patients on a ventilator
This study tests a medicine called prostacyclin (given through a vein) to see if it helps people on a breathing machine with a lung infection. The goal is to reduce inflammation and improve recovery.
CopenhagenAges 18 years+ - NCT07003672Recruiting
Weaning from ventilator: a lung measurement study
This study looks at people who have a tracheostomy and have been on a breathing machine for at least two weeks. Researchers want to see if certain lung measurements can help predict how easy or hard it will be to come off the ventilator.
TaipeiAges 20 years+ - NCT07256821Recruiting
Finding the best breathing muscle training dose in the ICU
This trial tests different amounts of inspiratory muscle training (IMT) for patients who have a tracheostomy tube and are on a breathing machine in the intensive care unit. Researchers want to find the dose that helps most with recovery.
MarlowAges 18 years+ - NCT07150650Enrolling by invitation
Biomarkers for ICU weakness in children on breathing machines
This study looks for early warning signs (biomarkers) of muscle weakness that can happen in children who need a breathing machine for more than a few days. If your child is in the PICU on a ventilator for at least 3 days, this team may be able to test for clues that help prevent or manage this weakness.
Shanghai, Shanghai MunicipalityAges 1 month–18 years - NCT07372924RecruitingPhase 2
Medicine for comfort during extended breathing tube use in the ICU
This trial tests a medicine called tegileridine fumarate to help patients who need a breathing tube for a long time in the ICU feel more comfortable. It may be an option if you or your loved one have been on a ventilator for several days.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT07219069Recruiting
Brain monitoring in ICU patients on a ventilator with sedation
This study is testing a special monitor (BIS) that tracks brain activity in patients on breathing machines and sedation. The goal is to see if it helps doctors provide better sedation care.
Cypress, TexasAges 18 years+ - NCT07212595RecruitingPhase 2
Amino acid therapy to protect kidneys after heart surgery in children
This trial is testing whether giving amino acids after heart surgery can help prevent kidney injury in children at high risk. If it works, it could offer a simple way to protect kidney function during recovery.
Cincinnati, OhioAges Up to 18 years - NCT07716787Recruiting
Brain monitoring during breathing therapy in critically ill patients
This study looks at how a breathing machine setting (called PEEP) affects blood flow in the brain. If you or your loved one is in the ICU with a serious brain injury and is on a breathing machine, this trial could help doctors understand how to make breathing therapy safer for the brain.
Dongying, ShandongAges 18 years+ - NCT03642002Recruiting
Music therapy for adults on breathing machines in the ICU
This trial tests whether music therapy can improve comfort and recovery for adults who need a breathing machine (mechanical ventilation) in the ICU for at least 48 hours. It may help with stress, mood, and other ICU-related symptoms while you are in critical care.
New York, New YorkAges 18 years+ - NCT03667027Recruiting
Study of breathing muscle and lung changes during transplant planning
This trial studies how the diaphragm (your main breathing muscle) and lung/airway tissue behave in people who are being supported until they can get a lung transplant. The results may help doctors better understand breathing failure and improve transplant care.
TorontoAges 18 years+ - NCT04110613Recruiting
Early feeding after PEG tube placement in ICU patients
This trial tests whether starting tube feeds soon after a PEG tube is placed is safe and helpful for mechanically ventilated ICU patients. PEG is a feeding tube placed through the belly, and early feeding may support recovery if your stomach can handle it.
Roanoke, VirginiaAges 18–100 - NCT04494074Recruiting
Cooling fever in ventilated people with septic shock
This study tests whether external cooling can safely lower very high fever in people who are on a breathing machine for septic shock. It may help improve outcomes by controlling fever while they are treated for the infection causing their illness.
AmiensAges 18 years+
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Common questions
- Are there clinical trials for mechanical ventilation?
- Yes. Clin2 currently lists 266 recruiting mechanical ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mechanical ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mechanical ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Mechanical Ventilation Complication
- Mechanical Ventilation Weaning
- Invasive Mechanical Ventilation
- Mechanical Ventilation Pressure High
- Prolonged Mechanical Ventilation
- Weaning Failure of Mechanical Ventilation
- Weaning Invasive Mechanical Ventilation
- Respiratory Insufficiency Requiring Mechanical Ventilation
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.