Clinical trials
Mechanical Ventilation clinical trials
Below are recruiting mechanical ventilation clinical trials, each written for real people, not researchers. We’re tracking 252 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07216755Recruiting
Breathing training and nitrate for altitude exercise
This study tests whether breathing training and a natural nitrate supplement (from beets) can improve how well you exercise in conditions that simulate high altitude. You'll do cycling workouts while we measure your performance.
Daytona Beach, FloridaAges 18–40 - NCT07212595RecruitingPhase 2
Amino acid therapy to protect kidneys after heart surgery in children
This trial is testing whether giving amino acids after heart surgery can help prevent kidney injury in children at high risk. If it works, it could offer a simple way to protect kidney function during recovery.
Cincinnati, OhioAges Up to 18 years - NCT07219069Recruiting
Brain monitoring in ICU patients on a ventilator with sedation
This study is testing a special monitor (BIS) that tracks brain activity in patients on breathing machines and sedation. The goal is to see if it helps doctors provide better sedation care.
Cypress, TexasAges 18 years+ - NCT03642002Recruiting
Music therapy for adults on breathing machines in the ICU
This trial tests whether music therapy can improve comfort and recovery for adults who need a breathing machine (mechanical ventilation) in the ICU for at least 48 hours. It may help with stress, mood, and other ICU-related symptoms while you are in critical care.
New York, New YorkAges 18 years+ - NCT04912960Recruiting
PEEP breathing support for adults with acute lung failure
This trial studies whether a specific breathing setting called PEEP can help adults whose lungs are failing and who need a breathing machine. Doctors will compare outcomes in patients who fit this critical illness pattern and are safe for the required positioning and ventilator settings.
Las Palmas de Gran Canaria, Las PalmasAges 18 years+ - NCT07199881Recruiting
Breathing effort study after major abdominal surgery
This study checks how your breathing effort changes with different levels of breathing support from the ventilator after major abdominal surgery. It helps doctors find the best settings to help you breathe comfortably while you recover.
Bangkok, BangkoknoiAges 18 years+ - NCT07175194Recruiting
Matching lung scans to ventilator settings in acute breathing failure
This study uses two lung imaging tests—CT scan and EIT (a non-invasive electrical test)—to find the best ventilator pressure for people with sudden breathing failure. The goal is to tailor settings to your lungs and potentially improve breathing support.
Milan, MilanAges 18 years+ - NCT07146698Recruiting
No sedation vs. daily sedation breaks for COPD patients on a ventilator
This trial compares not using sedation at all versus daily breaks in sedation for people with COPD who are on a breathing machine (ventilator) in the intensive care unit. It aims to see if one approach leads to better outcomes, such as shorter time on the ventilator.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT07150650Enrolling by invitation
Biomarkers for ICU weakness in children on breathing machines
This study looks for early warning signs (biomarkers) of muscle weakness that can happen in children who need a breathing machine for more than a few days. If your child is in the PICU on a ventilator for at least 3 days, this team may be able to test for clues that help prevent or manage this weakness.
Shanghai, Shanghai MunicipalityAges 1 month–18 years - NCT07150637Enrolling by invitation
Predicting muscle weakness in children on a breathing machine
This study aims to predict muscle weakness that can happen to children on breathing machines in the ICU. It could help doctors start treatments earlier to prevent this weakness.
Shanghai, Shanghai MunicipalityAges 1 month–18 years - NCT07120672Recruiting
Breathing tube removal success study
This study tests if a new method (PPI) can better predict when a patient is ready to have their breathing tube removed after a trial of spontaneous breathing.
IstanbulAges 18 years+ - NCT06421012Recruiting
Extra oxygen before breathing tube suctioning in the ICU
This study looks at whether giving extra oxygen before a breathing tube suctioning procedure (called tracheal aspiration) helps patients in the ICU who are on a breathing machine. It aims to make the procedure safer and more comfortable.
ParisAges 18 years+ - NCT07075926Recruiting
Heart ultrasound to predict breathing tube removal success in ICU
This study uses a heart ultrasound to see if it can help doctors predict when patients in the ICU are ready to have their breathing tube removed. It may help avoid failed extubations and reduce complications.
Istanbul, IstanbulAges 18 years+ - NCT05207046Recruiting
Study for people on a breathing machine after spine trauma
This trial studies how care is given to people who have a traumatic injury to the spine and need a breathing machine. It may help improve treatment and recovery for people who are ventilated after injury, including those with or without spinal cord damage.
Toronto, OntarioAges 16 years+ - NCT05710432Recruiting
Exercises to help breathing during ventilator weaning
This study tests whether specific neck and breathing muscle exercises during ventilator weaning can help people breathe more effectively and safely come off the ventilator. It may help patients who have already had trouble with prior weaning attempts.
Toronto, OntarioAges 16 years+ - NCT07066605Recruiting
Dexmedetomidine for agitation during breathing tube removal
This trial tests whether a sedative called dexmedetomidine can reduce agitation in ICU patients when they are being weaned off a breathing tube. If you experience restlessness or agitation during the weaning process, this medication might help you stay calm.
SohagAges 19 years+ - NCT07070843Recruiting
Comparing two eye care methods for ICU patients on ventilators
This study compares two different ways of caring for the eyes of intensive care patients on breathing machines. It aims to find which method better prevents eye problems like dryness or infection.
Istanbul, IstanbulAges 3 weeks+ - NCT07069959Recruiting
Measuring leg muscle recovery after ICU breathing support
This study checks how leg muscles recover after being in the ICU on a breathing machine. It uses a strength test and a special ultrasound to measure muscle health.
Nantes, Loire AtlantiqueAges 18 years+ - NCT07073976Recruiting
Predicting success of coming off the breathing machine using heart ultrasound
This study uses an ultrasound of the heart (echocardiogram) to check how well the right side of your heart is working. The goal is to see if that can help predict whether you will successfully come off the breathing machine.
Istanbul, IstanbulAges 18 years+ - NCT05515484RecruitingPhase 2
Test inflatable bag to help lungs work better when prone
This Phase 2 study tests whether using an inflatable air bag can improve how well the lungs stretch and work for people with ARDS while they are lying face-down (prone) on a ventilator. If you qualify, the study may help determine whether this positioning support improves breathing and lung comfort.
AmiensAges 18 years+ - NCT06465082Recruiting
Can diaphragm ultrasound predict successful breathing tube removal?
This trial uses ultrasound to measure how well your diaphragm (the main muscle you use to breathe) thickens when you breathe in. The goal is to see if this measurement can help doctors decide the best time to remove the breathing tube safely.
Al MansurahAges 18 years+ - NCT07032987Recruiting
Improving sedation with a new care plan for ICU patients
This trial tests a new sedation protocol for adults in intensive care who need strong pain relief or sedation medicines. It aims to make sedation safer and more comfortable, and includes people on ECMO (a heart-lung machine) or a ventilator (breathing machine) for severe breathing problems.
London, LondonAges 18–100 - NCT07019636Recruiting
Direct extubation vs. extubation after a breathing trial
This study compares two ways of removing the breathing tube (extubation) in patients who are ready to breathe on their own: taking the tube out right away, or doing a trial of breathing without the machine first. It is for people who are at low risk of needing the tube put back in.
ParisAges 18–65 - NCT07003672Recruiting
Weaning from ventilator: a lung measurement study
This study looks at people who have a tracheostomy and have been on a breathing machine for at least two weeks. Researchers want to see if certain lung measurements can help predict how easy or hard it will be to come off the ventilator.
TaipeiAges 20 years+
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Common questions
- Are there clinical trials for mechanical ventilation?
- Yes. Clin2 currently lists 252 recruiting mechanical ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mechanical ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mechanical ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Mechanical Ventilation Complication
- Mechanical Ventilation Weaning
- Invasive Mechanical Ventilation
- Mechanical Ventilation Pressure High
- Prolonged Mechanical Ventilation
- Weaning Failure of Mechanical Ventilation
- Weaning Invasive Mechanical Ventilation
- Respiratory Insufficiency Requiring Mechanical Ventilation
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.