Clinical trials
Mechanical Ventilation clinical trials
Below are recruiting mechanical ventilation clinical trials, each written for real people, not researchers. We’re tracking 252 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07002710Recruiting
Long-term ventilation and inflammation study
This study looks at how long-term inflammation affects the breathing of people who have been on a ventilator for 10 days or more. It aims to help doctors better understand and support your recovery.
TaipeiAges 20 years+ - NCT06867354Recruiting
Breathing difficulty in obese patients during weaning from ventilator
This study looks at how often obese patients have trouble breathing when doctors try to remove the breathing tube (weaning) in the ICU. The goal is to understand what causes this and how it affects recovery.
Paris, ParisAges 18 years+ - NCT06977555Enrolling by invitation
Talking with ICU patients on a breathing machine
This study looks at how nurses and doctors communicate with patients who are awake but on a breathing machine (ventilator) in the intensive care unit (ICU). The goal is to improve communication and make the experience better for patients.
OsloAges 18 years+ - NCT06969443Recruiting
Studying rehab practices in the intensive care unit
This study watches how patients in the intensive care unit are helped to move and strengthen their muscles (rehabilitation) during their stay. It does not give any new treatment or medicine, but simply documents what usual care looks like for people who need a breathing tube for more than two days.
ParisAges 18 years+ - NCT06938217Enrolling by invitation
Low-flow ECMO for adults with severe breathing failure
This study tests whether a gentler, low-blood-flow version of ECMO (a machine that helps oxygenate blood outside the body) is safe and effective for adults with very severe breathing failure. It is for patients who are already on a breathing machine and have very low oxygen levels despite that support.
San Antonio, TexasAges 18–65 - NCT06919484Recruiting
RCexp effect on lung air and blood flow in ARDS
This study tests a new technique (RCexp) to see how it affects air and blood flow in the lungs of people with ARDS who are on a breathing machine. It aims to improve how we monitor and treat lung problems.
Nanjing, JiangsuAges 19 years+ - NCT06903052Recruiting
App for parents managing child's breathing tube symptoms
This trial tests a mobile app that helps parents care for their child who needs a breathing tube at home. The app provides support and tips for managing symptoms, so parents feel more confident and prepared.
Kowloon, KowloonAges 2–18 - NCT06835842Recruiting
Rib mobilization for pneumonia patients on a ventilator
This study tests whether a gentle rib movement technique (called rib mobilization) can help people with pneumonia who are on a breathing machine get ready to breathe on their own. It aims to see if this therapy makes it easier to wean off the ventilator.
CairoAges 40–50 - NCT06832306Recruiting
Diaphragm pacing for breathing support in ICU
This trial tests a device that helps stimulate the diaphragm to improve breathing in patients who need a ventilator. It's for people with new breathing problems who have been in the ICU on a ventilator for less than 4 days.
La Jolla, CaliforniaAges 18 years+ - NCT06826794Recruiting
VentilO study for heart surgery patients on ventilators
This study tests a new way to monitor breathing in patients who are on a ventilator right after heart surgery. It may help doctors adjust settings more accurately.
Québec, QuebecAges 18 years+ - NCT06117683Recruiting
Testing a new breathing device during planned surgery
This trial compares a new breathing device (used with a hand-held bag) to a standard breathing machine during planned surgeries. Researchers want to see if the new device works just as well for people under general anesthesia.
Providence, Rhode IslandAges 18–80 - NCT06784037Enrolling by invitation
Best lung pressure during robotic lung surgery
This trial tests the best setting for air pressure in the lungs during robotic lung surgery without capnothorax. It aims to improve breathing and recovery after surgery.
Barcelona, CataloniaAges 18 years+ - NCT06694740RecruitingPhase 2/Phase 3
Interferon gamma for immune recovery in the ICU
This trial tests if a drug called interferon gamma can help boost the immune system of patients in the ICU who are fighting serious infections. It is for adults who are on a breathing machine and have low immune function.
ParisAges 18 years+ - NCT06692400Recruiting
Suctioning, pain, and blood markers in intubated patients
This study looks at how routine suctioning of the breathing tube affects pain levels and certain substances in the blood in adults who are on a breathing machine for serious infections like flu, pneumonia, COVID, or sepsis. It may help doctors better understand and manage your comfort during this procedure.
Loma Linda, CaliforniaAges 18 years+ - NCT06673862Enrolling by invitation
Detecting fluid needs with a breathing machine change
This trial checks if a simple change in ventilator settings (a tidal volume challenge) can predict whether you need more fluids, compared to a standard fluid challenge. It's for patients on a breathing machine who have low blood flow.
Banhā, Al-QalyubiaAges 18 years+ - NCT06319274RecruitingPhase 2
Prostacyclin for lung infection patients on a ventilator
This study tests a medicine called prostacyclin (given through a vein) to see if it helps people on a breathing machine with a lung infection. The goal is to reduce inflammation and improve recovery.
CopenhagenAges 18 years+ - NCT06602557RecruitingPhase 2
Inhaled antibiotic for lung infection during ECMO support
This trial tests whether adding an inhaled antibiotic (amikacin) to standard IV antibiotics can better treat a serious lung infection (pneumonia caused by Gram-negative bacteria) in patients on a heart-lung machine (ECMO) and a breathing tube. If you or your loved one is on ECMO and has this type of pneumonia, this study may offer a new treatment approach.
ParisAges 18 years+ - NCT06612242Recruiting
Early vs. late tracheostomy in Guillain-Barre patients
This trial looks at whether having a tracheostomy (a breathing tube placed through the neck) earlier or later helps people with Guillain-Barre syndrome who need a breathing machine. It reviews past cases to see which timing leads to better recovery.
Kfar SabaAges 18 years+ - NCT06595602Recruiting
Intelligent lung support in the ICU
This trial tests a smart breathing machine that adjusts support automatically for people on a ventilator. It may help make breathing more comfortable and reduce lung injury.
DresdenAges 18 years+ - NCT06579157Recruiting
Using pressure-sensing mattresses to help newborns breathe on their own
This trial tests whether a special mattress that senses breathing movements can help doctors decide when to remove breathing support from newborns. It may reduce the time babies need a breathing machine.
New Taipei CityAges Up to 1 year - NCT06563544Recruiting
Two ventilator settings for asthma and COPD patients
This study compares two different ways of delivering breaths from a ventilator for people with severe asthma or COPD. The goal is to see which method might be better for your lungs.
Rotterdam, South HollandAges 18–100 - NCT06532994Recruiting
Prediction tool for recovery after critical illness
This study looks at how well people recover after critical illness. It tests a prediction tool to help guide rehabilitation for patients who needed a breathing machine and started rehab in the ICU.
Wuhan, HubeiAges 18–90 - NCT06479655RecruitingPhase 4
Comparing fentanyl and morphine for ICU sedation
This study compares two different pain and sedation medicines (fentanyl and morphine) given continuously through an IV to help patients who are on a breathing machine (ventilator) in the ICU. The goal is to see which medicine works better and is safer for keeping you comfortable and calm.
Kota Bharu, KelantanAges 18 years+ - NCT06454006Recruiting
Light therapy for patients on breathing machines
This study tests a light therapy (called PBMT-sMF) on people in the ICU who need a breathing machine. It aims to see if the treatment helps muscles and recovery.
Porto Alegre, Rio Grande do SulAges 21 years+
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Common questions
- Are there clinical trials for mechanical ventilation?
- Yes. Clin2 currently lists 252 recruiting mechanical ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mechanical ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mechanical ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Mechanical Ventilation Complication
- Mechanical Ventilation Weaning
- Invasive Mechanical Ventilation
- Mechanical Ventilation Pressure High
- Prolonged Mechanical Ventilation
- Weaning Failure of Mechanical Ventilation
- Weaning Invasive Mechanical Ventilation
- Respiratory Insufficiency Requiring Mechanical Ventilation
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.