Clinical trials
Mechanical Ventilation clinical trials
Below are recruiting mechanical ventilation clinical trials, each written for real people, not researchers. We’re tracking 266 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06421012Recruiting
Extra oxygen before breathing tube suctioning in the ICU
This study looks at whether giving extra oxygen before a breathing tube suctioning procedure (called tracheal aspiration) helps patients in the ICU who are on a breathing machine. It aims to make the procedure safer and more comfortable.
ParisAges 18 years+ - NCT06454006Recruiting
Light therapy for patients on breathing machines
This study tests a light therapy (called PBMT-sMF) on people in the ICU who need a breathing machine. It aims to see if the treatment helps muscles and recovery.
Porto Alegre, Rio Grande do SulAges 21 years+ - NCT07656259Recruiting
Comparing breathing support methods in the heart ICU
This study compares different ways to support breathing in patients who need a ventilator in the cardiac intensive care unit. It aims to find the best approach for people with certain heart conditions, like cardiogenic shock or heart failure.
Rochester, MinnesotaAges 18 years+ - NCT06501118Recruiting
Oxygen levels in ICU patients on breathing machines
This study tests whether giving a little more oxygen to ICU patients on breathing machines leads to better recovery. It compares usual oxygen levels to a more liberal target to see which is safer and more effective.
Aurora, ColoradoAges 18 years+ - NCT06532994Recruiting
Prediction tool for recovery after critical illness
This study looks at how well people recover after critical illness. It tests a prediction tool to help guide rehabilitation for patients who needed a breathing machine and started rehab in the ICU.
Wuhan, HubeiAges 18–90 - NCT06563544Recruiting
Two ventilator settings for asthma and COPD patients
This study compares two different ways of delivering breaths from a ventilator for people with severe asthma or COPD. The goal is to see which method might be better for your lungs.
Rotterdam, South HollandAges 18–100 - NCT06579157Recruiting
Using pressure-sensing mattresses to help newborns breathe on their own
This trial tests whether a special mattress that senses breathing movements can help doctors decide when to remove breathing support from newborns. It may reduce the time babies need a breathing machine.
New Taipei CityAges Up to 1 year - NCT06586736Recruiting
Prone position study for ARDS patients
This trial studies how lying face down (prone position) affects breathing in patients with acute respiratory distress syndrome (ARDS). It may help doctors better monitor and treat patients on a breathing machine.
Chengdu, SichuanAges 18–90 - NCT06612242Recruiting
Early vs. late tracheostomy in Guillain-Barre patients
This trial looks at whether having a tracheostomy (a breathing tube placed through the neck) earlier or later helps people with Guillain-Barre syndrome who need a breathing machine. It reviews past cases to see which timing leads to better recovery.
Kfar SabaAges 18 years+ - NCT06694740RecruitingPhase 2/Phase 3
Interferon gamma for immune recovery in the ICU
This trial tests if a drug called interferon gamma can help boost the immune system of patients in the ICU who are fighting serious infections. It is for adults who are on a breathing machine and have low immune function.
ParisAges 18 years+ - NCT06769308Recruiting
Brain wave guided sedation in ICU patients
This study tests a new way to give pain and sedation medicines in the ICU. It uses a special brain wave monitor (EEG) to help doctors adjust your medicines more precisely, aiming to keep you comfortable and safe.
Ferrara, ItalyAges 18–90 - NCT06808997Recruiting
Study on breathing support decisions for very early preterm babies
This study looks at how doctors decide when to remove the breathing tube (extubation) from extremely preterm babies born before 28 weeks of pregnancy. It aims to understand what affects breathing outcomes and could help improve care for these tiny infants.
AmiensAges 1 minute–5 months - NCT06826794Recruiting
VentilO study for heart surgery patients on ventilators
This study tests a new way to monitor breathing in patients who are on a ventilator right after heart surgery. It may help doctors adjust settings more accurately.
Québec, QuebecAges 18 years+ - NCT06829290Recruiting
How muscle loss affects disease course in GI cancers
This study looks at how loss of muscle mass (sarcopenia) affects the course of illness in people with gastrointestinal cancers, liver cirrhosis, or those in the ICU. It will help doctors better understand and treat muscle wasting.
Mainz, Rhineland-PalatinateAges 18 years+ - NCT06835842Recruiting
Rib mobilization for pneumonia patients on a ventilator
This study tests whether a gentle rib movement technique (called rib mobilization) can help people with pneumonia who are on a breathing machine get ready to breathe on their own. It aims to see if this therapy makes it easier to wean off the ventilator.
CairoAges 40–50 - NCT06867354Recruiting
Breathing difficulty in obese patients during weaning from ventilator
This study looks at how often obese patients have trouble breathing when doctors try to remove the breathing tube (weaning) in the ICU. The goal is to understand what causes this and how it affects recovery.
Paris, ParisAges 18 years+ - NCT06911450Recruiting
Ultrasound test for lung strain in ICU patients
This study uses a special ultrasound technique to measure how the lungs stretch (pleural strain) during breathing. It aims to see if this measurement works in ICU patients, both those breathing on their own and those on a ventilator, and how it relates to the pressure needed to inflate the lungs.
Wuhu, AnhuiAges 18–75 - NCT06914336Recruiting
Liver ultrasound to check fluid buildup in ventilated patients
This trial uses an ultrasound of your liver to see if there is extra fluid or pressure in your veins that might make it harder to breathe. It may help doctors understand how to better manage the breathing machine for people who have been on it for more than a day.
BrestAges 18 years+ - NCT06919484Recruiting
RCexp effect on lung air and blood flow in ARDS
This study tests a new technique (RCexp) to see how it affects air and blood flow in the lungs of people with ARDS who are on a breathing machine. It aims to improve how we monitor and treat lung problems.
Nanjing, JiangsuAges 19 years+ - NCT06999603RecruitingPhase 2
Inhaled study drug for virus infections on ventilators
This study tests an inhaled study drug (SNG001) for adults on a breathing machine in the ICU due to a viral lung infection. The goal is to see if the drug can help patients recover faster.
Sacramento, CaliforniaAges 18 years+ - NCT07032987Recruiting
Improving sedation with a new care plan for ICU patients
This trial tests a new sedation protocol for adults in intensive care who need strong pain relief or sedation medicines. It aims to make sedation safer and more comfortable, and includes people on ECMO (a heart-lung machine) or a ventilator (breathing machine) for severe breathing problems.
London, LondonAges 18–100 - NCT07070843Recruiting
Comparing two eye care methods for ICU patients on ventilators
This study compares two different ways of caring for the eyes of intensive care patients on breathing machines. It aims to find which method better prevents eye problems like dryness or infection.
Istanbul, IstanbulAges 3 weeks+ - NCT07146698Recruiting
No sedation vs. daily sedation breaks for COPD patients on a ventilator
This trial compares not using sedation at all versus daily breaks in sedation for people with COPD who are on a breathing machine (ventilator) in the intensive care unit. It aims to see if one approach leads to better outcomes, such as shorter time on the ventilator.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT07175194Recruiting
Matching lung scans to ventilator settings in acute breathing failure
This study uses two lung imaging tests—CT scan and EIT (a non-invasive electrical test)—to find the best ventilator pressure for people with sudden breathing failure. The goal is to tailor settings to your lungs and potentially improve breathing support.
Milan, MilanAges 18 years+
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Common questions
- Are there clinical trials for mechanical ventilation?
- Yes. Clin2 currently lists 266 recruiting mechanical ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mechanical ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mechanical ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Mechanical Ventilation Complication
- Mechanical Ventilation Weaning
- Invasive Mechanical Ventilation
- Mechanical Ventilation Pressure High
- Prolonged Mechanical Ventilation
- Weaning Failure of Mechanical Ventilation
- Weaning Invasive Mechanical Ventilation
- Respiratory Insufficiency Requiring Mechanical Ventilation
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.