Clinical trials
Muscle clinical trials
Below are recruiting muscle clinical trials, each written for real people, not researchers. We’re tracking 1,109 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05013255RecruitingPhase 2
Pioglitazone to treat fatigue in hormone-positive breast cancer
This Phase 2 study tests whether pioglitazone can reduce fatigue in people with certain types of breast cancer. You may be eligible if your cancer is estrogen- and progesterone-positive (ER+/PR+) and you plan surgery soon.
Morgantown, West VirginiaAges 18 years+ - NCT07215104Recruiting
Spinal cord stimulation for chronic low back pain
This trial tests a special type of spinal cord stimulation (called BurstDR) in people with chronic low back pain. If you already have a spinal cord stimulator and it helps your pain, researchers want to see if adding muscle stimulation can provide even more relief.
Charleston, West VirginiaAges 18 years+ - NCT07213063Recruiting
Creatine and HMB supplements for Down syndrome
This trial tests whether taking creatine and HMB supplements can improve muscle strength, reduce inflammation, and increase muscle mass in people with Down syndrome. It may help if you or your loved one can do basic physical tests like standing from a chair and do not have kidney disease or severe mobility issues.
Burgos, BurgosAges 18 years+ - NCT06654986Recruiting
Test of muscle building with a beta-2 agonist and added amino acids
This study tests how a medicine (beta-2 agonist) combined with extra amino acids (building blocks of protein) affects muscle growth. It looks at how your body builds new muscle in response to these two things together.
CopenhagenAges 18–40 - NCT07206225RecruitingPhase 1
Study of PF-08052667 in non-muscle invasive bladder cancer
This trial tests a new study medicine called PF-08052667 for people with a certain type of bladder cancer that hasn't spread into the muscle. It's for those who have already tried BCG treatment and can't or won't have their bladder removed.
Birmingham, AlabamaAges 18 years+ - NCT07206797Recruiting
Ultrasound to measure muscle activity from spinal cord stimulation
This study uses ultrasound to see how muscles respond to two types of electrical stimulation (spinal cord and functional electrical stimulation). It may help researchers better understand how to treat muscle weakness or paralysis.
Raleigh, North CarolinaAges 18–60 - NCT07210788Recruiting
Crowning time and pelvic floor muscle health
This study looks at how the time spent pushing during delivery affects the muscles that support the pelvic floor. It may help first-time mothers understand how to protect these muscles.
Sherbrooke, QuebecAges 18 years+ - NCT07208916Recruiting
Can eating grapes boost strength and thinking in older women?
This study tests whether eating grapes daily can help improve muscle strength and memory in healthy women aged 65 and older. If you join, you will need to follow a special diet that limits certain foods and supplements.
Springfield, MassachusettsAges 65 years+ - NCT06937190Recruiting
Does creatine before sleep improve power in active women?
This study tests if taking a small dose of creatine before bed helps women who exercise regularly perform better on power-based activities like jumping and sprinting. It's designed for healthy, young women who already do resistance training and want to see if a simple supplement can boost their nighttime recovery and next-day performance.
Shabestar, East Azerbaijan ProvinceAges 18–25 - NCT07196332Recruiting
Recovering sleep after a car accident
This study tests a remote therapy program to help people who have been in a car accident and are at risk for PTSD. The goal is to see if improving sleep soon after a trauma can prevent PTSD symptoms.
Chapel Hill, North CarolinaAges 18–65 - NCT07203040Enrolling by invitation
Ultrasound therapy for neck pain relief and muscle stiffness
This trial tests if a gentle ultrasound treatment can reduce neck pain and stiffness. It may be an option if you have ongoing neck pain and haven't had neck procedures recently.
ErzurumAges 18–50 - NCT07202780Enrolling by invitation
MS and Muscle Strength in Breathing and Legs
This study looks at how MS affects the strength of your breathing muscles and leg muscles. If you join, you will have tests to measure your muscle strength, walking ability, and fatigue. This may help doctors understand how to better treat MS-related weakness.
Gaziantep, şehitkamilAges 18–50 - NCT07202819Recruiting
Chemotherapy and MRI before bladder surgery
This study looks at how well MRI scans can detect bladder cancer after chemotherapy, before surgery to remove the bladder. It may help doctors know if the chemo is working.
Asyut, Asyut GovernorateAges 18 years+ - NCT07198568Recruiting
Swallowing and Neck Muscle Activity in Sarcopenic Dysphagia
This study looks at how the muscles in your neck and throat work when you swallow, specifically in older adults who have both sarcopenia (low muscle mass) and trouble swallowing. The goal is to better understand the connection between swallowing and muscle activity, which may help develop better treatments.
Incheon, Jung-guAges 65 years+ - NCT07198750Recruiting
Pulsed magnetic field therapy for knee osteoarthritis in older adults
This trial tests two types of high-intensity pulsed electromagnetic field therapy (one using two modes, another using one mode) to see if they can reduce pain and improve function in older adults with knee osteoarthritis. You would attend 9 treatment sessions and do exercises at home.
Guadalajara, JaliscoAges 60 years+ - NCT06944782Recruiting
Can mouth muscle tests help diagnose sleep apnea?
This study tests a new device that measures muscle activity in your mouth to diagnose sleep apnea—without needing to spend the night in a lab. If you've already had a sleep test showing either no sleep apnea or moderate to severe sleep apnea, and you're not using CPAP daily, you may be able to help.
San Diego, CaliforniaAges 18–80 - NCT07188350Recruiting
Electrical muscle stimulation for patients on a breathing machine
This trial tests whether low-level electrical pulses to the leg muscles can help prevent weakness in patients who need a breathing tube (ventilator) for more than 48 hours. It aims to see if this treatment helps patients recover faster.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07187635Recruiting
Urine DNA test before a second bladder tumor surgery
This trial studies if a urine test for tumor DNA can help decide when a second surgery is needed for early stage bladder cancer. It may reduce unnecessary procedures for some patients.
Nanchang, AnhuiAges 18 years+ - NCT06944730Recruiting
Trunk muscle training for better movement and balance in low back pain
This study tests whether trunk muscle training can improve the quality of your movements and balance if you have chronic low back pain. It is designed for people with moderate pain and no other major health issues.
Hong KongAges 18–55 - NCT07179042Enrolling by invitationEarly Phase 1
Metformin for hip fracture recovery in older adults
This study tests whether the diabetes drug metformin can help older adults recover better after hip fracture surgery. To join, you need to be 60+, have had a low-energy hip fracture fixed within 3 days, and be generally healthy without diabetes or kidney issues.
Salt Lake City, UtahAges 60–90 - NCT07176988Recruiting
Voice therapy study for certain voice problems
This study tests a behavioral voice therapy approach for people with voice issues caused by muscle tension or benign vocal fold lesions. It aims to improve communication and requires participants to attend sessions and practice with a smartphone.
Atlanta, GeorgiaAges 16–65 - NCT06259877Recruiting
Breathing, balance, and function after a stroke
This study tests how breathing muscle strength, balance, and trunk control relate to daily function after a stroke. It aims to help you recover better.
KirikkaleAges 18 years+ - NCT07166198Recruiting
Stopping age-related muscle weakness in women during inactivity
This study tests if a gentle hand exercise or a noninvasive brain stimulation can prevent muscle weakness in middle-aged women when they limit arm use for a period. It may help protect your strength and nerve function during recovery or downtime.
Manhattan, KansasAges 40–65 - NCT07164846Recruiting
FES suit for recovery after injury or amputation
This trial tests a special suit that uses mild electrical stimulation to help improve muscle strength, walking, and body functions. It may help people who are at least one week past an amputation or a nervous system injury like stroke or spinal cord injury.
Jacksonville, FloridaAges 18 years+
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Common questions
- Are there clinical trials for muscle?
- Yes. Clin2 currently lists 1,109 recruiting muscle studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.