Clinical trials
Oxygenation clinical trials
Below are recruiting oxygenation clinical trials, each written for real people, not researchers. We’re tracking 383 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07257588Enrolling by invitation
Hyperbaric oxygen for severe ulcerative colitis
This study tests whether adding hyperbaric oxygen therapy—breathing pure oxygen in a pressurized chamber—to standard care can help people with a severe flare of ulcerative colitis (a type of inflammatory bowel disease). It may reduce inflammation and speed up recovery.
Xi'an, ShaanxiAges 18 years+ - NCT07252102Recruiting
High-flow oxygen during sedation for critical patients having GI endoscopy
This trial tests whether high-flow nasal oxygen (HFNC) reduces low oxygen levels during sedated gastrointestinal procedures. It is for patients with higher health risks (ASA grade III–IV) who need an endoscopy or treatment.
Shenzhen, GuangdongAges 18–80 - NCT06811870RecruitingPhase 1/Phase 2
Hyperbaric oxygen before surgery for breast cancer
This trial tests adding hyperbaric oxygen (breathing pure oxygen in a pressurized chamber) before standard chemotherapy for breast cancer. The goal is to see if it helps shrink the tumor more effectively before surgery.
Guangzhou, GuangdongAges 18–60 - NCT07222410Recruiting
Smart oxygen control for COPD patients on nasal high flow
This trial tests a smart oxygen system that automatically adjusts oxygen levels for people with COPD who are in the hospital using a nasal high-flow device. It may help keep your oxygen levels stable without needing constant adjustments.
Birmingham, AlabamaAges 22 years+ - NCT07214415RecruitingPhase 2
Hyperbaric oxygen therapy for veterans with brain injury or mental health issues
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, mood, and quality of life in veterans with mild traumatic brain injury, PTSD, anxiety, or depression. You must have already tried at least one evidence-based therapy like CBT or EMDR.
Boise, IdahoAges 18–75 - NCT05883137Recruiting
High-flow nasal oxygen during intubation in the ICU
This trial looks at using a special, fast-flow oxygen device through the nose during intubation in critically ill adults. It may help keep oxygen levels safer while a breathing tube is placed.
Stockholm, Stockholm CountyAges 18–100 - NCT07200180RecruitingPhase 3
Argon gas to protect brain function after carotid surgery
This trial tests if breathing argon gas during and after surgery can help prevent thinking and memory problems in patients having carotid artery surgery. If effective, it could speed up recovery.
MoscowAges 18 years+ - NCT06948942Recruiting
Exercise ability in interstitial lung disease
This study compares exercise capacity, muscle oxygen levels, and physical activity between people with interstitial lung disease (ILD) and healthy volunteers. It aims to understand how ILD affects daily movement and overall fitness.
AnkaraAges 18–75 - NCT06930443Recruiting
Oxygen use and organ injury after heart-lung bypass surgery
This trial looks at how oxygen is used during heart surgery that uses a heart-lung machine, and whether low oxygen levels can lead to organ damage. It may help doctors better understand how to protect patients during surgery.
Uppsala, SwedenAges 18 years+ - NCT07109570Recruiting
Checking breathing effort in ICU patients on a ventilator
This trial measures how your breathing muscles work while we try taking you off the breathing machine. The results could help doctors predict when you're ready to breathe on your own.
LeidenAges 18 years+ - NCT07108764Recruiting
Medicine to prevent confusion after abdominal surgery in seniors
This trial tests giving either lidocaine or dexmedetomidine during abdominal surgery to see if it helps keep the brain healthy and lowers the chance of waking up confused or agitated. It is for older adults having planned abdominal surgery who are otherwise in fairly good health.
Tanta, El-GharbiaAges 65 years+ - NCT03033251Recruiting
Compare high-flow oxygen to noninvasive ventilation for COPD flare-ups
This study compares two breathing support options for people hospitalized with a COPD flare-up and high carbon dioxide levels in the blood. It aims to see which option works better and is safer for breathing and recovery.
Toronto, OntarioAges 40 years+ - NCT06247397Recruiting
High-flow therapy for long-term oxygen users
This trial tests if adding high-flow oxygen therapy to your usual long-term oxygen therapy can help you breathe better. It is for people with COPD or ILD who use oxygen at home for at least 15 hours a day.
Karlskrona, Blekinge CountyAges 18 years+ - NCT05526534Recruiting
Breathing treatment to prevent lung problems after gynecologic surgery
This trial studies whether a breathing support therapy given after surgery can reduce the chance of lung complications. It focuses on people having gynecologic tumor surgery who are at higher risk for breathing or lung problems.
Chengdu, SichuanAges 18–90 - NCT07062367Recruiting
Anesthesia options for laparoscopic hysterectomy and brain health
This study compares three ways to give anesthesia during laparoscopic hysterectomy: one type of gas (sevoflurane) with or without a lidocaine IV drip, versus a different IV anesthesia (propofol). The goal is to see which approach best protects pressure inside your head and oxygen levels in your brain during surgery.
Tanta, El-GharbiaAges 18–65 - NCT07051980RecruitingPhase 2
Oxygen through a tube above the voice box for sedated ERCP
This study tests a new way to deliver oxygen during a sedated ERCP, using a thin tube placed above the voice box instead of a breathing tube. It aims to see if this method is safe and practical for people having this procedure.
Hangzhou, ZhejiangAges 18 years+ - NCT07049692Recruiting
Hyperbaric oxygen after stroke clot removal study
This trial tests if hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can help people recover better after having a stroke caused by a large clot in the front part of the brain. It is for people who recently had a clot removal procedure and have some remaining disability but are still awake and aware.
Beijing, Beijing MunicipalityAges 35–75 - NCT07004699Recruiting
Comparing two breathing methods during throat and esophagus exams
This study compares two ways of helping you breathe while you are sedated for an endoscopy of your throat, voice box, and esophagus. It aims to find which method is safer and more comfortable for patients like you.
La Roche-sur-YonAges 18 years+ - NCT06819644RecruitingPhase 3
Adjusting oxygen therapy using a depth camera to measure lung volumes
This trial tests whether adjusting high flow oxygen therapy (which delivers warm, moist oxygen through the nose) based on a new, non-contact technology — a depth camera that measures lung volumes without touching you — can help improve breathing in people with low oxygen levels. It's for patients in respiratory distress who need oxygen but don't have chronic lung disease.
BrestAges 18 years+ - NCT06814340RecruitingPhase 3
CPAP on ECMO for severe lung failure
This trial is for people with severe lung failure (ARDS) who are already on a life-support machine called VV-ECMO. It tests whether adding a special breathing tube (CPAP) can help their lungs heal better.
BobignyAges 18 years+ - NCT06776939Recruiting
High-flow oxygen through trach tube to help weaning from a ventilator
This trial tests if high-flow oxygen delivered through a tracheostomy tube can make mucus less sticky and reduce breathing effort while you are being taken off a ventilator. It could help you breathe easier during weaning.
RotterdamAges 18 years+ - NCT03976180Recruiting
High-flow oxygen for painful sickle cell episodes
This trial tests whether giving high-flow oxygen can help treat a painful sickle cell “vaso-occlusive crisis” (VOC) and lower the risk of a serious lung complication. You may be eligible if you’re an adult with sickle cell disease experiencing an opioid-requiring pain flare and have higher risk for lung trouble.
CréteilAges 18 years+ - NCT06104956Recruiting
Weaning from high-flow oxygen therapy in the ICU
This trial is testing a way to safely reduce high-flow oxygen therapy for patients in the ICU who have low oxygen levels. It might help find the right time to stop this treatment.
BloisAges 18–90 - NCT06748586Recruiting
Hyperbaric oxygen therapy and stem cell study
This study checks if hyperbaric oxygen therapy (HBOT) increases the number of stem cells circulating in your blood. You may qualify if you are already scheduled for HBOT for another reason and are willing to give blood samples.
ZrifinAges 20–80
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Common questions
- Are there clinical trials for oxygenation?
- Yes. Clin2 currently lists 383 recruiting oxygenation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a oxygenation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a oxygenation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.