Clinical trials
Pain, Chronic Disease clinical trials
Below are recruiting pain, chronic disease clinical trials, each written for real people, not researchers. We’re tracking 457 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06087510RecruitingPhase 4
Different doses of esketamine and dexmedetomidine for pain after scoliosis surgery
This trial tests two different doses of esketamine and dexmedetomidine to see which provides better pain relief after scoliosis correction surgery. It aims to improve your recovery and long-term outcomes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04500665RecruitingPhase 2
Colchicine for kidney-related heart inflammation
This Phase 2 trial tests whether colchicine can reduce inflammation and improve heart function in people with kidney disease and a certain type of heart problem. If you qualify, you’ll be closely monitored for side effects and lab changes.
Boston, MassachusettsAges 21–80 - NCT05833048Recruiting
Pain-relief nerve block during cardiac surgery
This study tests whether a numbing “nerve block” placed in the rectus sheath area can reduce pain for people having certain heart surgeries with chest tubes. If you qualify, it may help your comfort during recovery, but it also depends on how suitable you are for local anesthesia.
New York, New YorkAges 18–85 - NCT03524222Recruiting
Home hospital care for adults after sudden illness
This trial tests whether certain adults can safely receive hospital-level care at home instead of staying in the hospital, using a home care team. It may help you recover in your own home if your condition fits their plan and you have support at home.
Boston, MassachusettsAges 18 years+ - NCT07317518Recruiting
Taping for chronic low back pain
This trial tests two different kinesio taping methods for people with chronic low back pain. The goal is to see how taping affects the fascia (connective tissue) in the lower back and whether it can help relieve pain.
Center, Kirşehi̇rAges 18–65 - NCT07846163Recruiting
Pain assessment for chronic low back pain
This study looks at how the brain and nervous system process pain in people with long-lasting low back pain. It uses safe measurements inside a shielded room to compare chronic pain patients with healthy people, which may help improve pain treatments.
Thessaloniki, Central MacedoniaAges 18–45 - NCT04824248Recruiting
Weight-loss program for chronic low back pain
This trial studies whether weight loss can improve long-lasting, non-specific low back pain. It may help people whose back pain is partly related to extra weight by testing a structured approach over time.
BrusselsAges 18–65 - NCT07338045Recruiting
Baduanjin exercise for chronic low back pain in office workers
This trial tests whether an eight-week Baduanjin exercise program can reduce chronic low back pain and improve daily function in office workers. Baduanjin is a gentle mind-body practice that involves slow movements and breathing, and it may help relieve pain caused by prolonged sitting.
Xi'an, ShaanxiAges 20–55 - NCT07216417Recruiting
Virtual yoga for chronic low back pain
This study tests whether a virtual yoga program can help reduce chronic low back pain. You'll attend online yoga classes from home, and the study will also ask about your experience.
Kansas City, KansasAges 30–80 - NCT06724029Recruiting
Neurosurgery outcomes research for multiple conditions
This study collects data from people having brain or spine surgery for many different conditions. It aims to understand how well different treatments work and how people recover. If you are scheduled for certain brain, spine, or nerve surgeries, you may be able to join.
Bergamo, BGAges 18 years+ - NCT04273828Recruiting
Study of muscle changes in chronic low back pain surgery
This study looks at how muscle degeneration relates to nerve-related symptoms in people with chronic low back pain. You may be eligible if you’ve tried non-surgical care but still need surgery to relieve nerve pressure.
São Paulo, São PauloAges 18 years+ - NCT07878273Recruiting
Tibial nerve size in chronic plantar fasciitis
This study compares the size of a nerve in the foot (the tibial nerve) between people with chronic plantar fasciitis and healthy individuals. It aims to understand if nerve changes are linked to this condition, which might help improve future treatments.
IstanbulAges 18–65 - NCT06438471RecruitingPhase 1
Study of a new drug for nerve pain after spinal cord injury
This trial tests an experimental pill for people with spinal cord injury who have long-term nerve pain. It aims to see if the drug can reduce pain and be safe.
Augusta, GeorgiaAges 18 years+ - NCT06068322Recruiting
Very intense interval training for people with COPD
This study tests whether a very intense, short burst of exercise (supramaximal high-intensity interval training) is safe and effective for people aged 60 and older with or without COPD. It aims to see if this type of exercise can improve fitness and daily life.
Hasselt, DiepenbeekAges 60 years+ - NCT07776379Recruiting
Predicting recovery with BDNF blood levels in chronic low back pain
This study looks at whether a protein in your blood, called BDNF, can help predict how well you might do with chronic low back pain. By participating, you may help doctors better understand and treat this condition.
Daegu, DaeguAges 20–80 - NCT07776366Recruiting
Study of disc protein levels and disc wear
This study looks at a protein called periostin in the discs of the lower back to see if it relates to how worn down the discs are, which might help improve future treatments.
Daegu, DaeguAges 20–80 - NCT07684820RecruitingPhase 2
A study of ExPD-101 for COPD with chronic bronchitis and frequent flare-ups
This study tests an experimental drug (ExPD-101) given daily as a pill for 52 weeks for people with COPD who have chronic bronchitis and frequent flare-ups. It compares the drug to a placebo (inactive pill) to see if it reduces flare-ups and improves symptoms.
Phoenix, ArizonaAges 40–85 - NCT07557108Recruiting
Nerve Blocks to Improve Recovery After Heart Surgery
This study tests whether special numbing injections around nerves in the chest wall (fascial plane blocks) help patients recover better and have less pain after open-heart surgery. The goal is to see if this technique improves how you feel and function in the days after your operation.
Ordu, AltinorduAges 18–70 - NCT06205875Recruiting
High vs. low dose pain block after minimally invasive heart valve surgery
This trial compares two doses of a numbing medicine injected into the chest wall to control pain after heart valve surgery. If you qualify, you will receive either a higher or lower dose of the pain block to see which provides better pain relief and recovery.
Hasselt, LimburgAges 18 years+ - NCT06915012Recruiting
Test of light therapy for long-term severe arthritis pain
This study tests a non-drug therapy called biophoton therapy to see if it can reduce chronic severe arthritis pain. It may be an option if you've had pain for at least 3 months and are not using certain medical implants.
Butler, PennsylvaniaAges 18–80 - NCT06827379Enrolling by invitation
Breathing exercise for muscle and nerve health in COPD
This trial tests whether a special breathing exercise (inspiratory muscle training) can improve how your muscles work and your body's automatic responses, like heart rate. It's a one-time session for people with stable COPD.
João Pessoa, ParaíbaAges 40–75 - NCT06749262Recruiting
Inclined vs. standard exercise for COPD
This study compares walking on an incline to standard walking for people with COPD. It aims to find which exercise method is better for improving breathing and mobility.
Omaha, NebraskaAges 45–80 - NCT06716411Recruiting
Acupuncture for Gulf War Illness relief
This study tests whether acupuncture can help relieve Gulf War Illness symptoms like fatigue, mood or thinking problems, and muscle or joint pain. You may be able to join if you were deployed to the Gulf region and have had these symptoms for more than 6 months.
Berkeley, CaliforniaAges 18 years+ - NCT06778447Recruiting
Trial of disc tissue injection for degenerative disc disease
This study tests an experimental treatment that injects donated disc tissue (called an allograft) into damaged discs in your lower back. It's designed for people with chronic low back pain from disc degeneration who haven't found relief from non-surgical treatments.
Napa, CaliforniaAges 22–85
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Common questions
- Are there clinical trials for pain, chronic disease?
- Yes. Clin2 currently lists 457 recruiting pain, chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain, chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain, chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.