Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07104825Recruiting
Nerve block for pain after weight loss surgery
This trial tests if a nerve block can help control pain after gastric bypass or sleeve gastrectomy. The goal is to reduce the need for strong pain medicines and improve recovery.
Evanston, IllinoisAges 18–90 - NCT07731737Recruiting
Biofeedback vs foam roller for knee osteoarthritis
This trial compares two non-surgical therapies—pressure biofeedback and foam rolling—to see which better reduces pain, improves muscle function, and boosts quality of life in people with early-stage knee osteoarthritis.
LahoreAges 45–65 - NCT07729930Recruiting
Creatine supplement study for healthy middle-aged women
This study is testing a creatine supplement (a substance that may help with energy and muscle function) in healthy middle-aged women. You may join if you are between 35 and 65, a non-smoker, and have a certain activity level.
LoughboroughAges 35–65 - NCT07458360Recruiting
Front block for better recovery after hip replacement
This study tests if a special nerve block called the front block (pericapsular nerve group block) improves recovery after hip replacement surgery. You may be eligible if you are having hip replacement under spinal anesthesia and do not have certain health issues.
KonyaAges 18 years+ - NCT07335263Recruiting
Swaddling or nesting for pain in newborns
This study tests if gently wrapping (swaddling) or positioning (nesting) your baby helps reduce pain and stress while they are on breathing support. It's for newborns who are breathing fast but otherwise healthy.
Merkez, KütahyaAges birth–4 weeks - NCT07728695RecruitingPhase 1/Phase 2
Cannabis product for gynecologic pain study
This trial tests a new cannabis-based product to see if it helps with gynecologic pain (like endometriosis). It looks at how the product works and whether it is safe and effective.
Belmont, MassachusettsAges 21 years+ - NCT07426796Recruiting
Comparing two pain blocks for pediatric testicle surgery
This trial compares two types of numbing injections for pain after surgery to fix an undescended testicle in young boys. It aims to find which injection works better for comfort during recovery.
IstanbulAges 1–7 - NCT06723158Recruiting
Virtual reality glasses for oral surgery with sedation
This trial tests if wearing virtual reality (VR) glasses during oral surgery helps patients relax while under IV sedation. It may be a good option if you need sedation for a tooth extraction or other mouth procedure.
Boston, MassachusettsAges 16–65 - NCT07426731Recruiting
Comparing two pain blocks for hypospadias surgery in boys
This trial tests two different ways to numb the area for hypospadias repair surgery in young boys. It aims to find which method works better to manage pain after the operation.
IstanbulAges 1–7 - NCT05508360Recruiting
Testing an artificial spacer implant for one-level low back pain
This study tests whether inserting a small artificial implant into a single painful disc can reduce long-term low back pain and disability. It’s for people who tried non-surgical treatments for at least 6 months but still have significant symptoms from degenerative disc disease.
Medellín, AntioquiaAges 22 years+ - NCT07724847Recruiting
Validating new criteria for diagnosing axial spondyloarthritis
This study aims to confirm new classification criteria for axial spondyloarthritis, a type of inflammatory arthritis affecting the spine and sacroiliac joints. Participants with chronic back pain lasting at least 3 months and starting before age 45 will undergo a series of tests to see if these new criteria better identify the condition.
Beijing, Beijing MunicipalityAges 18–45 - NCT07724691Recruiting
Comparing two shoulder therapies for frozen shoulder
This study compares two types of gentle shoulder movements (mobilizations) to treat frozen shoulder. The goal is to reduce pain and help you move your arm more easily.
Lahore, Punjab ProvinceAges 30–50 - NCT05561595Recruiting
Reducing health-related stigma through group support
This trial tests a virtual group program to help people cope with health-related stigma from conditions like obesity, cancer, HIV, diabetes, skin disease, or chronic pain. It aims to reduce internalized stigma and improve well-being.
Gainesville, FloridaAges 18 years+ - NCT07711626Recruiting
Foot massage and ear stimulation for head and neck cancer symptoms
This study tests whether foot massage (reflexology) and a mild nerve-stimulation device on the ear can help reduce side effects during chemotherapy and radiation for head and neck cancer.
Hualien CityAges 30–75 - NCT07486232Enrolling by invitation
Neck pain relief with posture exercises and taping
This study tests whether combining postural exercises with taping can help people with long-term neck pain who work at a desk. It aims to find a simple way to reduce pain and improve comfort.
IstanbulAges 25–55 - NCT06013878Recruiting
Testing a tool for caregivers who help with transfers
This study tests a special instrument to measure how caregivers help people with physical disabilities move from one place to another (transfers). It may help improve safety and technique for both caregivers and care recipients.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07297901Enrolling by invitation
Breathing app study for migraine relief
This trial tests a smartphone-based breathing program to help reduce migraines. It uses heart rate data to guide breathing exercises tailored to you.
Phoenix, ArizonaAges 18 years+ - NCT07721220Recruiting
Nerve gliding moves for strength and endurance in athletes
This study tests whether a gentle nerve-stretching technique (neurodynamics) can improve leg strength and endurance in athletes. If you're 18–30, currently active in sports or intense training, and have no recent leg injury or surgery, you may be able to join.
High Point, North CarolinaAges 18–30 - NCT07720739Recruiting
Adding morphine to a spine block for belly surgery pain
This study tests whether adding a small dose of morphine to a numbing injection near the spine (called erector spinae plane block) provides better pain relief after midline belly surgery. It may help reduce the need for other pain medicines and improve recovery.
SohagAges 18–60 - NCT07714785Recruiting
EEG-guided anesthesia for better recovery after tonsillectomy
This study tests whether using brain-wave monitoring (EEG) during anesthesia with sevoflurane can reduce the amount of pain medicine needed after tonsillectomy and improve how smoothly children wake up. It could help your child have a more comfortable recovery.
Santiago, RegiónAges 2–8 - NCT07640126Recruiting
Acupuncture for cold-sensitive neck pain
This trial tests whether a specific type of acupuncture (three-needle Dazhui plus electroacupuncture) can reduce pain and improve function in people with neck pain caused by cervical spondylosis, especially when the pain is worse in cold weather. It combines a modern diagnosis with traditional Chinese medicine ideas to see if this approach helps more than standard care.
Ho Chi Minh CityAges 3 weeks+ - NCT07662850Recruiting
Rehab after ACL surgery: blood flow training and soft tissue work
This study tests if combining blood flow restriction training with a special manual technique (IASTM) helps reduce pain, build strength, improve knee movement, and lower fear of re-injury after ACL reconstruction. It is for people who are 8 to 16 weeks past surgery and already have good knee bending.
Lahore, Punjab ProvinceAges 18–40 - NCT07124494Recruiting
Anesthesia type and recovery after knee replacement
This study compares two types of anesthesia for total knee replacement to see which helps with pain, movement, and satisfaction after surgery. If you are scheduled for a knee replacement and are willing to have a spinal or epidural anesthesia, you may be able to join.
Konya, MeramAges 18 years+ - NCT07715682Recruiting
Gentle touch and calm for premature babies' blood tests
This study tests whether gentle human touch and fewer distractions can help reduce pain and improve comfort for premature babies during a standard heel-prick blood test.
AnkaraAges 7 months–9 months
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.