Clinical trials
Radiation Therapy clinical trials
Below are recruiting radiation therapy clinical trials, each written for real people, not researchers. We’re tracking 686 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06555471RecruitingPhase 2
Sintilimab plus chemo-radiation for older adults with advanced stomach cancer
This trial tests whether adding the immunotherapy drug sintilimab to standard chemoradiotherapy can help people aged 75 or older with locally advanced stomach cancer. It aims to shrink tumors and improve outcomes.
Nanjing, JiangsuAges 75 years+ - NCT06574880RecruitingPhase 1/Phase 2
Radiation and Lutetium PSMA for locally advanced prostate cancer
This study tests a combination of focused radiation (SBRT) and a targeted radioactive drug (Lutetium PSMA) for men with prostate cancer that has spread to nearby lymph nodes or has high-risk features but has not yet reached distant organs. The goal is to see if this approach is safe and effective.
Cleveland, OhioAges 18 years+ - NCT06586255RecruitingPhase 1
Immunotherapy and radiation after bladder cancer surgery
This trial tests whether adding radiation therapy to immunotherapy after bladder removal surgery can help prevent cancer from coming back. It's for people with advanced bladder cancer who have already started immunotherapy.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06594887Recruiting
Rectal spacer use during proton therapy for prostate cancer
This trial tests how well a rectal spacer works when you get proton beam therapy for prostate cancer. The spacer is a gel placed between your prostate and rectum to protect healthy tissue.
Somerset, New JerseyAges 18 years+ - NCT06139627Recruiting
Geriatric assessment for older adults with lung cancer getting chemotherapy and radiation
This trial tests whether a special geriatric assessment can help manage side effects for adults aged 60 and older with non-small cell lung cancer who are starting a new treatment plan that includes chemotherapy and radiation. It aims to improve quality of life and treatment outcomes.
Duarte, CaliforniaAges 60 years+ - NCT06611150RecruitingPhase 1
Chemo and radiation for advanced nasopharyngeal cancer
This trial tests whether a specific chemotherapy drug (nab-paclitaxel) given along with targeted radiation therapy can help people with stage III or IVa nasopharyngeal cancer. The goal is to improve treatment outcomes while managing side effects.
Guangzhou, GuangdongAges 18–70 - NCT06623656RecruitingPhase 2
Pre-surgery treatment comparison for non-small cell lung cancer
This trial compares two treatment approaches before surgery for non-small cell lung cancer (NSCLC): radiation plus immunotherapy versus chemotherapy plus immunotherapy. The goal is to see which combination works better to shrink the tumor before it is removed.
New York, New YorkAges 18 years+ - NCT06635980RecruitingPhase 2
Radiation before or after breast cancer surgery
This trial compares two ways of giving radiation for breast cancer that has not spread: before or after surgery. It aims to see if giving radiation first might work as well or better.
Scottsdale, ArizonaAges 18 years+ - NCT06642220RecruitingPhase 2
Y-90 radioembolization for kidney cancer
This trial tests a procedure called Y-90 radioembolization for patients with kidney cancer tumors larger than 4 cm who cannot have or choose not to have surgery. The treatment delivers tiny radioactive beads through a blood vessel to the tumor to destroy cancer cells while limiting damage to healthy tissue.
London, OntarioAges 18 years+ - NCT06648148Recruiting
Molecular markers for radiation response in breast cancer
This trial looks for biomarkers (biological signs) in breast tissue that might predict how well breast cancer responds to radiation therapy. It is for patients with ductal carcinoma in situ (DCIS) who are scheduled to receive radiation after surgery.
LjubljanaAges 18–75 - NCT06650579RecruitingPhase 3
Heart safety study of relugolix vs leuprolide for prostate cancer
This trial compares two hormone therapy combinations for men with prostate cancer that hasn't spread. The goal is to see if a newer oral medication (Relugolix) plus abiraterone works better than the standard injectable therapy (Lupron) plus abiraterone, while also checking heart safety.
Atlanta, GeorgiaAges 18 years+ - NCT06651853RecruitingPhase 2
Radiation therapy with lenalidomide and glofitamab for DLBCL
This trial tests a combination of radiation therapy, lenalidomide, and glofitamab for people with a type of lymphoma called DLBCL that has not responded to or has returned after initial treatment. The goal is to see if this combination can help when other treatments have failed.
Xiamen, FujianAges 18 years+ - NCT06660628Recruiting
Radiation therapy with or without breath-hold for left breast cancer
This study compares two types of radiation therapy for left breast cancer: one using a breath-holding technique to protect the heart, and another without it. The goal is to see which is safer and more effective for women who have had surgery.
Beijing, Beijing MunicipalityAges 18–70 - NCT06691776Recruiting
Adaptive radiotherapy for five cancer types
This trial tests whether a newer type of daily CT scan (CBCT-guided adaptive radiotherapy) can safely and accurately deliver radiation to cancers of the prostate, cervix, bladder, lung, or head and neck. The goal is to better target the tumor and reduce side effects.
AmsterdamAges 18 years+ - NCT06692062Recruiting
Hypofractionated radiation for thymoma and thymic carcinoma
This trial tests a shorter course of radiation (hypofractionated radiotherapy) for people with thymoma or thymic carcinoma. It aims to see if fewer, larger doses of radiation are safe and effective for treating these tumors.
Changsha, HunanAges 18–75 - NCT06700863Recruiting
Finding biomarkers for head and neck cancer radiation therapy
This study is looking for proteins or other substances in the blood (biomarkers) that can help predict how well head and neck cancer patients respond to radiation therapy. If you have head and neck cancer and are scheduled for radiation, possibly with chemo, immunotherapy, or targeted therapy, you may be able to join.
Nanjing, JiangsuAges 18–70 - NCT06702033RecruitingPhase 2
Surgery for HPV-related oropharyngeal cancer
This trial is testing a surgical approach for people with HPV-related oropharyngeal cancer that is stage I or II (but not the very smallest). The goal is to see if removing the tumor through the mouth and taking out neck lymph nodes is effective and safe. It may be an option if you are healthy enough for surgery.
St Louis, MissouriAges 18 years+ - NCT06704555RecruitingPhase 2
Radiation plus drug combo for untreated bulky follicular lymphoma
This trial tests a combination of radiation, an immunotherapy drug (tislelizumab), and chemotherapy (RCHOP) for people with previously untreated bulky follicular lymphoma. It aims to see if giving radiation first followed by the drug combo can improve outcomes for larger tumors.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT06704659Recruiting
Repeated radiation for recurrent breast cancer
This study tests giving a second round of radiation therapy to women whose breast cancer has come back in the same breast, at least 3 years after their first radiation. It may be an option for women 55 and older who have a small, local recurrence that can be removed with surgery.
HelsinkiAges 55 years+ - NCT06734598RecruitingPhase 4
Botox for Jaw Tightness After Head and Neck Radiation
This study tests whether Botox injections into the jaw muscles can help head and neck cancer survivors who have trouble opening their mouths (trismus) after radiation therapy. If you have tight or painful jaw muscles and limited mouth opening, this treatment may offer relief.
TaipeiAges 18 years+ - NCT06739655Recruiting
Radiation before surgery with breast reconstruction
This trial tests whether giving radiation therapy before surgery (instead of after) is safe and effective for women with breast cancer who also want immediate breast reconstruction. It could help avoid the need for a second surgery and improve recovery.
Edegem, AntwerpenAges 18 years+ - NCT06743789Recruiting
Radiation therapy for ventricular tachycardia: one or three sessions
This trial tests whether a single session of targeted radiation (radioablation) is as effective as three sessions for treating a dangerous heart rhythm called ventricular tachycardia in people with heart muscle disease. It's for those who continue to have episodes despite medication and catheter ablation.
New York, New YorkAges 18–90 - NCT06769126RecruitingPhase 2
Personalized treatment study for extensive stage small cell lung cancer
This study uses biomarker tests on your tumor to find a personalized treatment after initial chemotherapy. You will be assigned to one of four treatment groups based on your biomarker results.
Loma Linda, CaliforniaAges 18 years+ - NCT06780787RecruitingPhase 2
Study of chemo plus immunotherapy for localized rectal cancer before surgery
This trial tests a combination of chemotherapy (FOLFOX) and two immunotherapies (botensilimab and balstilimab) before surgery for patients with localized rectal cancer. It aims to see if adding immunotherapy helps shrink the tumor and improve outcomes.
Duarte, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for radiation therapy?
- Yes. Clin2 currently lists 686 recruiting radiation therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiation therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiation therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.