Clinical trials
Regurgitation clinical trials
Below are recruiting regurgitation clinical trials, each written for real people, not researchers. We’re tracking 200 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06101888Recruiting
New Heart Valve for Severe Aortic Leak
This study is testing a new, less invasive heart valve system (TaurusTrio) for people with severe aortic regurgitation (a leaky aortic valve) who cannot have open-heart surgery. It aims to see if the valve is safe and works well to improve symptoms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06381271Recruiting
TAVR for severe aortic valve regurgitation
This trial tests a procedure called TAVR to replace the aortic valve in people with severe aortic regurgitation (a leaky valve). It may help you if you have this condition and prefer a less invasive option than open-heart surgery.
Xi'an, ShannxiAges 18 years+ - NCT05655897Recruiting
Clips for leaky mitral valve in high-surgery-risk heart patients
This trial studies whether a device called GeminiOne can safely and effectively repair a leaky mitral valve using a catheter-based “clip” technique. It may help patients who have moderate-to-severe or severe valve leakage but are considered too high-risk for open surgery.
Suzhou, JiangsuAges 18 years+ - NCT07793916Recruiting
Heart device and tricuspid valve function study
This study looks at how heart devices like pacemakers affect the tricuspid valve over time. It uses ultrasound to check valve function and see if the device causes any problems.
Seoul, SeoulAges 19 years+ - NCT06634121Recruiting
Comparing MitraClip and PASCAL for mitral valve repair
This trial compares two devices (MitraClip and PASCAL) for repairing a leaky mitral valve (mitral regurgitation). The goal is to see which device works better in a wide range of patients who need this type of repair.
Munich, BavariaAges 18 years+ - NCT07709208Recruiting
Mitral valve repair for leak that worsens with exercise
This trial tests a procedure to fix a leaky mitral valve that only becomes severe during exercise. It may help people with symptoms like shortness of breath or fatigue who haven't responded to standard heart medications.
DüsseldorfAges 18 years+ - NCT04913727Recruiting
Testing heart scan predictions after mitral valve repair
This trial studies severe secondary mitral valve leaking and uses heart imaging to predict how well the heart and symptoms improve after a less-invasive valve procedure. It may help doctors better forecast who benefits most from this repair.
BernAges 18 years+ - NCT07677410Recruiting
Aspirin alone vs. aspirin with warfarin after TAVR for aortic regurgitation
This trial tests whether taking aspirin alone is as safe and effective as taking aspirin with warfarin after a TAVR procedure for severe aortic regurgitation. It is for people who do not need long-term blood thinners for other conditions.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06684171Recruiting
Comparing two ways to guide mitral valve clip repair
This trial tests whether using only ultrasound (echo) to guide a mitral valve clip repair is as good as using ultrasound plus X-ray. The study may help patients with a leaky mitral valve who are not good candidates for open heart surgery.
Shenzhen, GuangdongAges Any age - NCT07617974Recruiting
Heart valve changes in atrial fibrillation patients
This study looks at how atrial fibrillation (a common heart rhythm problem) affects the tricuspid valve—one of your heart's four valves. Researchers will use special ultrasound imaging to understand these changes and help improve future treatment.
Milan, MilanAges 18 years+ - NCT07539298RecruitingPhase 2/Phase 3
Valsartan for Heart-Related Mitral Valve Leaking
This study tests whether a blood pressure medication called valsartan can reduce leaking in the mitral valve (a valve in your heart) caused by an enlarged left chamber. The goal is to see if this medication can improve heart function and reduce symptoms without needing surgery.
Québec, QuebecAges 18–85 - NCT07528781Recruiting
New 3D Ultrasound Method for Measuring Heart Valve Leakage
This study tests a new way to measure leakage in the mitral valve (a valve in your heart) using advanced 3D ultrasound. If you have moderate or severe mitral valve leakage, this research may help doctors better understand and treat the condition.
Badalona, BarcelonaAges 18–95 - NCT07517588Recruiting
Mitral Valve Repair Using Polares System for Heart Failure
This trial tests a minimally invasive procedure to repair a leaky mitral valve (the valve between the upper and lower chambers of your heart) in people with heart failure who haven't improved with medication alone. The procedure uses a catheter-based system inserted through the groin to replace part of the valve, potentially reducing symptoms and improving heart function.
Atlanta, GeorgiaAges 21 years+ - NCT07486271Recruiting
AI in Aortic Regurgitation trial
This trial uses artificial intelligence to help measure aortic regurgitation, a heart valve problem. It aims to improve how doctors assess and treat this condition.
Hong Kong, New TerritoriesAges 18 years+ - NCT07470788Recruiting
Vesalius TMVr system for leaky heart valve (mitral regurgitation)
This study tests a new device called the Vesalius TMVr system to fix a leaky mitral valve without open-heart surgery. It's for people with severe mitral regurgitation who are not good candidates for surgery.
VancouverAges 19 years+ - NCT07453407Recruiting
Tavi valve vs surgery for severe aortic regurgitation
This trial compares a new catheter-based valve (J-Valve) with open-heart surgery for people with severe aortic regurgitation, a condition where the aortic valve doesn't close tightly. It aims to see which treatment is safer and more effective.
Hefei, AnhuiAges 65 years+ - NCT07414225Recruiting
MitraClip procedure for atrial functional mitral regurgitation
This trial tests a minimally invasive procedure to repair a leaky mitral valve in people with a specific type of heart failure. The goal is to see if the procedure, called transcatheter edge-to-edge repair (TEER), is safe and effective in reducing symptoms and improving heart function.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06823700Recruiting
Study of SQ-Kyrin device for leaky mitral valve from heart failure
This trial tests a new device (SQ-Kyrin) to fix a leaky mitral valve without open-heart surgery. It is for people with heart failure whose valve leak causes symptoms, and who are not good candidates for traditional surgery.
Valladolid, ValladolidAges 18 years+ - NCT07398911Enrolling by invitation
3D simulated TAVR for aortic valve leak
This trial tests whether a 3D computer simulation can help guide a less invasive procedure (TAVR) to replace a leaky aortic valve. It may be an option for people with severe aortic regurgitation who are at least 65 years old.
Xi’an, ShanxiAges 65 years+ - NCT07385625Recruiting
Studying a new device for severe tricuspid valve leakage
This trial tests a device called the Pivot Bridge System to treat severe leakage of the tricuspid valve (the valve between the right upper and lower heart chambers). The goal is to see if it safely reduces symptoms like swelling and shortness of breath.
Daegu, Dalseo-guAges 18 years+ - NCT06838611Recruiting
Study of patients with severe tricuspid regurgitation
This study is collecting information about people with severe tricuspid regurgitation (a leaky heart valve) who are having a catheter-based repair. The goal is to better understand these patients and how well the procedure works for them.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT07342036Recruiting
Study of new heart device leads and tricuspid valve leakage
This study looks at how a new pacemaker or defibrillator lead may affect the tricuspid valve (the valve between the right upper and lower heart chambers). It helps doctors understand if the lead causes leakage (regurgitation) over time.
Bad Oeynhausen, North Rhine-WestphaliaAges 18 years+ - NCT06212193Recruiting
Trillium Stent Graft for Leaky Heart Valve
This trial tests a new stent graft device (Trillium) placed through a vein to help fix a severely leaky tricuspid valve without open-heart surgery. It is for people with severe symptoms who cannot have or have not improved with standard treatments.
Thousand Oaks, CaliforniaAges 18–85 - NCT07321899Recruiting
Study of a new tricuspid valve replacement device for severe leakage
This trial tests a new device called the Medtronic Intrepid TTVR system to replace the tricuspid valve in people with severe tricuspid regurgitation (leaky valve). It aims to see if the device can safely and effectively fix the leak and improve symptoms.
Birmingham, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for regurgitation?
- Yes. Clin2 currently lists 200 recruiting regurgitation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a regurgitation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a regurgitation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.