Clinical trials
Regurgitation clinical trials
Below are recruiting regurgitation clinical trials, each written for real people, not researchers. We’re tracking 201 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06137807Recruiting
TricValve for severe tricuspid regurgitation
This trial is testing a new device called the TricValve to treat severe tricuspid regurgitation (a leaky heart valve on the right side). It is for people who still have symptoms despite taking heart failure medications.
Phoenix, ArizonaAges 18 years+ - NCT06212193Recruiting
Trillium Stent Graft for Leaky Heart Valve
This trial tests a new stent graft device (Trillium) placed through a vein to help fix a severely leaky tricuspid valve without open-heart surgery. It is for people with severe symptoms who cannot have or have not improved with standard treatments.
Thousand Oaks, CaliforniaAges 18–85 - NCT06307262Recruiting
European registry for tricuspid valve repair
This trial is a registry that collects information on patients who have had a minimally invasive procedure to fix a leaky tricuspid valve. By joining, you help doctors learn more about how well these devices work over time.
Munich, BavariaAges 18 years+ - NCT06329817Recruiting
Regurgitation risk during intubation: semi-fowler vs supine
This trial compares two positions (semi-fowler and supine) during intubation to see which reduces regurgitation risk. It may help if you are an adult scheduled for intubation.
Rawalpindi, Punjab ProvinceAges 18–60 - NCT06381271Recruiting
TAVR for severe aortic valve regurgitation
This trial tests a procedure called TAVR to replace the aortic valve in people with severe aortic regurgitation (a leaky valve). It may help you if you have this condition and prefer a less invasive option than open-heart surgery.
Xi'an, ShannxiAges 18 years+ - NCT06414265Recruiting
Testing a new valve for severe mitral regurgitation
This trial tests a new device called the SATURN system, which places a new mitral valve without open-heart surgery. It is for people aged 65 and older with severe mitral regurgitation who are at high risk for surgery.
TbilisiAges 65 years+ - NCT06554119Recruiting
Surgery for tricuspid valve leaks after prior heart surgery
This study looks at different surgeries for a leaky tricuspid valve that happened after earlier heart surgery. It may help doctors learn which approach works best for patients like you.
Guangzhou, GuangdongAges 16 years+ - NCT06630936Recruiting
Studying atrial fibrillation with mitral regurgitation
This trial tests a treatment for people with atrial fibrillation who also have a leaky mitral valve. It aims to see if treating both conditions together can improve symptoms.
Hangzhou, ZhejiangAges 18–80 - NCT06634121Recruiting
Comparing MitraClip and PASCAL for mitral valve repair
This trial compares two devices (MitraClip and PASCAL) for repairing a leaky mitral valve (mitral regurgitation). The goal is to see which device works better in a wide range of patients who need this type of repair.
Munich, BavariaAges 18 years+ - NCT06675448Recruiting
Best practices for heart failure with leaky mitral valve
This trial compares two treatment approaches for people with heart failure and a leaky mitral valve (mitral regurgitation). It aims to find which strategy leads to better outcomes. You may be eligible if your heart function is reduced and you have symptoms despite standard treatments.
Falls Church, VirginiaAges 18–99 - NCT06684171Recruiting
Comparing two ways to guide mitral valve clip repair
This trial tests whether using only ultrasound (echo) to guide a mitral valve clip repair is as good as using ultrasound plus X-ray. The study may help patients with a leaky mitral valve who are not good candidates for open heart surgery.
Shenzhen, GuangdongAges Any age - NCT06608823Recruiting
Comparing surgery vs. the Trilogy valve for aortic regurgitation
This trial compares a new less-invasive valve replacement (Trilogy TAVR) with standard open-heart surgery for people with significant aortic regurgitation. It aims to see which treatment works better for patients who are eligible for both procedures.
Burlingame, CaliforniaAges Any age - NCT06780241Recruiting
Sex differences in valvular heart disease
This study uses special MRI scans to look at how valvular heart disease (like leaky or narrowed aortic valves) affects men and women differently. It aims to find unique biological patterns that could lead to better treatments.
Cleveland, OhioAges 18–90 - NCT06818084RecruitingPhase 4
TAVR for severe aortic regurgitation using VitaFlow Liberty
This trial tests the VitaFlow Liberty device, a catheter-based treatment for people with severe aortic regurgitation (a leaky heart valve). If you have symptoms or your heart is starting to weaken, this procedure might help avoid open-heart surgery.
Shanghai, Shanghai MunicipalityAges 60 years+ - NCT06835946Recruiting
How anesthesia and imaging affect heart valve leak assessment
This study looks at how anesthesia, breathing machines, and imaging methods change the way doctors measure a leaky heart valve. It aims to make sure the severity of aortic regurgitation is accurately measured before surgery.
LiègeAges 18 years+ - NCT06838611Recruiting
Study of patients with severe tricuspid regurgitation
This study is collecting information about people with severe tricuspid regurgitation (a leaky heart valve) who are having a catheter-based repair. The goal is to better understand these patients and how well the procedure works for them.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT06876883Recruiting
Mitral regurgitation risk assessment study
This study looks at people with moderate or severe mitral regurgitation (a leaky heart valve) to better understand their risks and create models to guide treatment. It may help your doctor decide on the best care plan for you.
Guangzhou, GuangdongAges 18 years+ - NCT06883864Recruiting
Ablation for leaky valve with constant atrial fibrillation
This study tests whether a catheter ablation procedure (a way to fix abnormal heart rhythms) can help people who have both constant atrial fibrillation and severe mitral regurgitation (a leaky heart valve). It is for people whose heart valve leak is caused by the rhythm problem, not by valve damage.
Hefei, AnhuiAges 18–80 - NCT06911099Recruiting
Studying mitral valve repair for atrial regurgitation
This trial tests a minimally invasive procedure (transcatheter edge-to-edge repair) to fix a leaky mitral valve caused by an enlarged atrium, not by heart muscle damage. It might be an option if your mitral regurgitation is related to atrial issues and your heart's pumping strength is normal.
The Bronx, New YorkAges 18 years+ - NCT06917664RecruitingPhase 4
Treating moderate mitral regurgitation in heart surgery patients
This trial looks at how to treat moderate mitral regurgitation (a leaky heart valve) in people who are already having coronary artery bypass surgery (CABG). It aims to find the best way to manage this condition to improve heart function.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06922526Recruiting
Pacemaker and tricuspid valve health: long-term outcomes
This study looks at how pacemakers and similar heart devices affect the tricuspid valve over time and whether that leads to worse health outcomes. It may help you understand if your device is causing long-term changes.
JinanAges 18 years+ - NCT06926959Recruiting
Tricuspid regurgitation risk model study
This study aims to develop a risk model for tricuspid regurgitation, a condition where the heart valve doesn't close properly. It may help doctors better understand and treat this condition.
Guangzhou, GuangdongAges 18 years+ - NCT07042360Recruiting
Understanding tricuspid valve leakage with non-invasive tests
This trial uses safe, non-invasive tests to study people with moderate or severe tricuspid regurgitation (leaky valve on the right side of the heart). It aims to better understand the condition, which may lead to improved care in the future.
Hong Kong, ShatinAges 18 years+ - NCT07069673Recruiting
Abbott Cephea mitral valve disease registry
This study tracks people with mitral valve disease who receive the Cephea valve through a tube in an artery rather than open-heart surgery. It looks at how well the valve works over time.
Birmingham, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for regurgitation?
- Yes. Clin2 currently lists 201 recruiting regurgitation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a regurgitation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a regurgitation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.