Clinical trials
Respiratory Distress clinical trials
Below are recruiting respiratory distress clinical trials, each written for real people, not researchers. We’re tracking 220 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06514209Recruiting
Muscle relaxation levels in severe ARDS patients
This study is testing whether different levels of muscle relaxation (called neuromuscular blockade) during breathing support can improve lung function in people with serious ARDS. It might help doctors choose the best relaxation level for patients on a breathing machine.
Nanjing, JiangsuAges 3 weeks–85 years - NCT03963622Recruiting
Test of careful breathing support for severe lung distress
This study compares a more careful ventilation approach for people with severe lung breathing failure (ARDS). It aims to improve outcomes by using a specific strategy for how the ventilator controls breathing.
New York, New YorkAges 18 years+ - NCT07216053Recruiting
Lung ultrasound to predict breathing problems in late preterm babies
This study uses lung ultrasound to see if it can predict which late preterm babies (born 34–36 weeks) might have trouble breathing after birth. The goal is to find these babies early so they can get the right care sooner.
Hackensack, New JerseyAges 8 months–8 months - NCT07274527Recruiting
Amnioinfusion for babies exposed to thick meconium during labor
This trial tests whether adding fluid into the womb (amnioinfusion) during labor can protect a baby's lungs and health after being exposed to thick meconium (baby's first poop). It may help reduce breathing problems and improve long-term outcomes.
Milwaukee, WisconsinAges 18 years+ - NCT06819644RecruitingPhase 3
Adjusting oxygen therapy using a depth camera to measure lung volumes
This trial tests whether adjusting high flow oxygen therapy (which delivers warm, moist oxygen through the nose) based on a new, non-contact technology — a depth camera that measures lung volumes without touching you — can help improve breathing in people with low oxygen levels. It's for patients in respiratory distress who need oxygen but don't have chronic lung disease.
BrestAges 18 years+ - NCT06827184Recruiting
Best time for lying on stomach with severe lung failure
This trial is for people with severe lung failure (ARDS) who need a breathing machine. It tests how long lying on your stomach (prone position) helps improve breathing, by measuring changes in your body's oxygen levels and other vital signs.
TaipeiAges 18 years+ - NCT07211529Recruiting
Nerve block during chest surgery to reduce complications
This trial tests whether a numbing injection near the spine (paravertebral block) given during keyhole chest surgery can lower the risk of problems after surgery. It might help patients recover more comfortably.
Wuhan, HubeiAges 18–80 - NCT07030270Recruiting
Comparing surfactant delivery methods for preterm infants
This trial compares two ways to give surfactant (a substance that helps preterm babies' lungs work better) to preterm infants who need breathing support. It studies whether a small tube placed through the throat or a thin catheter works better for delivering the medication.
Dallas, TexasAges birth–3 days - NCT06421506Recruiting
Giving surfactant through a thin tube in late preterm babies
This trial tests a less invasive way to give surfactant (a lung treatment) to babies born a few weeks early who need breathing help. It aims to see if this method works as well as standard care.
LondonAges 8 months–9 months - NCT06083363Recruiting
Recovery after severe lung infection
This study follows patients who had severe pneumonia or acute respiratory distress syndrome (ARDS) in the intensive care unit (ICU) to understand how they recover over time. It aims to identify factors that affect recovery trajectories.
Tortosa, TarragonaAges 18 years+ - NCT04966624Recruiting
Ultrasound-guided breathing strategy for new focal ARDS
This study tests a way to guide ventilator settings using lung ultrasound pictures in adults with very new, localized ("focal") ARDS. The goal is to see whether this approach improves care for people who just started needing a breathing machine.
DijonAges 18 years+ - NCT05609877Recruiting
Testing LISA breathing treatment for very preterm newborns
This trial is studying whether giving a lung “surfactant” medicine through a thin tube (called LISA) helps very premature babies with breathing problems. It aims to see if this approach improves care for babies born around 24 to 30 weeks gestation who still need oxygen support.
AalborgAges 6 months–7 months - NCT06212492Recruiting
Muscle relaxants and stomach positioning for ARDS
This trial tests whether combining two treatments—medications that relax muscles (neuromuscular blocking agents) and lying on your stomach (prone positioning)—can reduce lung damage in people with severe ARDS on a breathing machine.
MarseilleAges 18 years+ - NCT06369584Recruiting
Prone Position for Children on ECMO with Severe ARDS
This trial tests if lying face-down (prone position) helps children with severe ARDS who are already on ECMO, a machine that supports the heart and lungs. It aims to see if this position improves recovery.
Beijing, Beijing MunicipalityAges 1 month–18 years - NCT05717218Recruiting
Testing special breathing monitoring during VV-ECMO in ARDS
This trial checks whether a special “breathing sensor belt” that watches breathing in real time can be used safely in adults with severe lung failure (ARDS) who are on a machine called VV-ECMO. It may help the care team better monitor ventilation while you’re critically ill.
ParisAges 18 years+ - NCT07669558Recruiting
Finding the best side-lying position for ARDS after abdominal surgery
This trial uses a special imaging test (electrical impedance tomography) to find the safest side position for patients with lung injury after abdominal surgery in the ICU. It aims to improve oxygen levels and breathing comfort.
ShanghaiAges 18 years+ - NCT07726940Recruiting
A Study of Immune Responses and ECMO in Severe Lung Injury
This study looks at how the immune system and ECMO (a machine that helps oxygenate blood) can improve outcomes for people with moderate to severe ARDS. If you join, researchers will monitor your condition and treatment to find better ways to manage this serious lung problem.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07726953Recruiting
Full-course ECMO for moderate-to-severe ARDS
This trial tests a full-course strategy using a heart-lung bypass machine (ECMO) for people with moderate-to-severe acute respiratory distress syndrome (ARDS), a serious lung condition. The goal is to see if starting and continuing ECMO throughout treatment improves recovery.
BeijingAges 18 years+ - NCT03825835Recruiting
Different oxygen levels at birth for very preterm babies
This trial studies whether giving 30% versus 60% oxygen during early resuscitation (breathing support) affects brain and nerve development in very low birthweight, very preterm infants. If you/your baby fits the birth and care timing requirements, the goal is to find an oxygen approach that supports better long-term outcomes.
Calgary, AlbertaAges birth–10 minutes - NCT04208126Recruiting
Early versus late ECMO start for severe lung failure
This trial compares starting ECMO early versus later in adults with severe lung failure (ARDS). It tests whether starting the life-support machine sooner can improve outcomes by the time doctors need it.
TübingenAges 18 years+ - NCT04221737Recruiting
Early breathing support for ARDS using a pressure release ventilator
This study looks at starting a specific type of breathing machine setting early in people with ARDS (a serious lung problem) to see if it improves outcomes. You might be able to take part if you are within 48 hours of needing a breathing tube and meet the lung oxygen criteria.
Guadalajara, JaliscoAges 18–80 - NCT04270045Recruiting
Breathing test in babies with bronchopulmonary dysplasia
This trial studies a breathing measurement test (forced oscillometry) in babies who were born early and have bronchopulmonary dysplasia (BPD), a long-term lung condition. It may help doctors better understand how babies’ lungs are working and guide future care.
Kansas City, MissouriAges Any age - NCT04460859Recruiting
Testing an electrical monitor in moderately severe lung failure
This trial tests a bedside breathing and lung-monitoring method that uses small electrodes on the chest. It is meant for people with moderate to severe ARDS (a serious lung inflammation problem) who are on a breathing machine, to help guide care.
São PauloAges 18 years+ - NCT04484727Recruiting
Measure lung pressure and breathing in ventilated ICU patients
This study measures lung pressures and breathing mechanics during planned or emergency breathing machine (ventilator) treatment. It may help doctors better understand lung behavior in both healthy and breathing-distressed lungs to improve care.
Gothenburg, Västra Götaland CountyAges 18 years+
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Common questions
- Are there clinical trials for respiratory distress?
- Yes. Clin2 currently lists 220 recruiting respiratory distress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory distress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory distress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Acute Respiratory Distress Syndrome
- Respiratory Distress Syndrome
- Respiratory Distress Syndrome, Newborn
- Respiratory Distress Syndrome in Premature Infant
- Respiratory Distress Syndrome (Neonatal)
- Respiratory Distress Neonatal
- Respiratory Distress Syndrome, Adult
- Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.