Clinical trials
Sepsis clinical trials
Below are recruiting sepsis clinical trials, each written for real people, not researchers. We’re tracking 267 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06440304RecruitingPhase 4
Comparing treatments for ICU patients with resistant Acinetobacter infections
This trial compares different treatment options for patients in the ICU who have a resistant bacterial infection called Acinetobacter baumannii. If you have this infection after surgery, the study aims to find the best way to treat it.
ZagrebAges 18–90 - NCT06440317Recruiting
Study of a special filter for kidney dialysis in septic shock
This trial tests whether a special type of dialysis filter (oXiris) helps reduce blood clotting problems in patients with septic shock and kidney failure. It may offer a better option for those needing kidney support in the ICU.
PessacAges 18 years+ - NCT06380842Recruiting
Organ function after necrosectomy for pancreatitis with sepsis
This study looks at how a surgery to remove dead tissue from the pancreas (called open necrosectomy) affects organ function in patients with acute pancreatitis and sepsis. It may help doctors understand how to better treat this serious condition.
Chengdu, ChinaAges 18 years+ - NCT06100614Recruiting
Using a blood test to reduce antibiotics in preterm newborns
This study checks if a blood test (presepsin) can help doctors safely stop antibiotics earlier in preterm babies at moderate risk of infection. The goal is to reduce unnecessary antibiotic use.
Amsterdam, North HollandAges Any age - NCT06193980Recruiting
ICU recovery exercise test study
This trial looks at how well your heart and lungs work together after a long stay in the ICU on a breathing machine. It uses a simple exercise test to check your recovery after leaving the hospital.
Winnipeg, ManitobaAges 18 years+ - NCT02143986Recruiting
Testing glycosylated ferritin to evaluate inflammation
This trial looks at a blood test called “glycosylated ferritin” to help doctors better identify certain dangerous inflammatory conditions. It may help clarify whether your high iron-related marker is due to inflammation rather than other causes.
BrusselsAges Up to 85 years - NCT05591924Recruiting
Bioinformatics study in adults with very early severe ICU illness
This trial studies how early severe illness in the ICU can be understood and tracked using health data (bioinformatics/informatics). It may help improve care decisions for people who arrive to the ICU soon after an emergency department visit.
London, OntarioAges 18 years+ - NCT06087315Recruiting
Study of oxygen use in children's hospitals
This study looks at how hospitals in six countries use pulse oximeters and oxygen therapy to treat children. It aims to find ways to improve oxygen delivery and care for children with serious illnesses.
Phnom PenhAges birth–15 years - NCT06058819Recruiting
New blood test to guide antibiotic use in newborns
This study is testing a new blood test to see if it can help doctors decide when to use antibiotics for newborns who may have a late-onset infection. The goal is to reduce unnecessary antibiotic use.
BronAges 1 week–2 weeks - NCT05926505RecruitingPhase 2/Phase 3
Anakinra for lingering symptoms after COVID-19
This Phase 2/3 trial studies whether anakinra can improve ongoing (post-acute) COVID-19 symptoms lasting for more than two months. It mainly looks for better safety and symptom improvement in people with specific inflammation and lung-related findings.
JenaAges 18 years+ - NCT05770622RecruitingPhase 4
Vancocin dosing check in young infants with infections
This trial studies a better way to monitor and adjust vancomycin (an antibiotic) dosing in very young infants. It may help your baby get the right dose while reducing the risk of under- or over-dosing.
Melbourne, VictoriaAges birth–3 months - NCT05692011Recruiting
Testing a blood-filter treatment in children with early sepsis
This trial looks at whether a blood-filter treatment (called “AN69ST Verse PS” using a hemofilter) can help children with early, serious sepsis and poor circulation or organ problems. It may help stabilize the body faster, but eligibility is limited to certain sepsis situations and recent timing.
Shanghai, Shanghai MunicipalityAges 4 weeks–28 years - NCT05604430Enrolling by invitation
Study of pre-hospital breathing support with a specific ventilator
This study looks at breathing support given outside the hospital using a particular ZOLL ventilator model and software version. If you were treated with the right equipment, the team will use the ventilator’s recorded data to evaluate how ventilation was delivered.
Hartford, ConnecticutAges Any age - NCT05336851Recruiting
Emergency breathing test study for sudden lung infections
This trial tests an emergency breathing-related approach for adults with a sudden, community-acquired respiratory infection. It may help doctors quickly sort out what’s going on and guide early care.
Hong KongAges 18–100 - NCT05357170Recruiting
Testing gut bacteria changes after severe ICU illnesses
This study looks at changes in the microbiome (gut bacteria) in adults after serious ICU illnesses like sepsis, major trauma, or open heart/abdominal surgery. It may help researchers understand why recovery can be harder in some people and guide future treatments.
Gainesville, FloridaAges 18–110 - NCT04961580Recruiting
Study of ceftazidime dosing in sick children
This trial measures how ceftazidime (an antibiotic) moves through the body and how it works in children with severe infections in the pediatric intensive care unit. It may help doctors choose safer, more effective dosing for kids.
Shanghai, Shanghai MunicipalityAges 3 months–18 years - NCT04886284RecruitingPhase 2
Cefazolin plus ertapenem for MSSA bloodstream infection
This Phase 2 study tests whether adding ertapenem to cefazolin can improve treatment of staphylococcus (“S. aureus”) bloodstream infection that is likely methicillin-susceptible (MSSA). It aims to start the right antibiotics quickly, before MRSA status is fully confirmed, using early testing and a treatment plan guided by infectious-disease specialists.
Calgary, AlbertaAges 18–100 - NCT04855786Recruiting
Drain lymph fluid to reduce inflammation in septic shock
This study tests whether draining fluid from a chest lymph channel can lower inflammation chemicals (cytokines) in people with septic shock. It’s done using a procedure and aims to see if this helps stabilize the body’s inflammatory response.
Philadelphia, PennsylvaniaAges 18–80 - NCT04794595Recruiting
Compare outcomes in children with and without CBP during sepsis
This study looks at children with sepsis to see how outcomes differ between those who receive a specific blood-cleansing treatment (CBP) and those who do not. Results may help clinicians choose treatments that lead to better recovery in sick children.
Shanghai, Shanghai MunicipalityAges 4 weeks–18 years - NCT04850456Recruiting
Gamma globulin treatment for critically ill children with inflammation surge
This trial studies whether giving “human gamma globulin” can improve outcomes in very sick children in the ICU who have a severe infection causing an extreme inflammation reaction (“inflammatory storm”). If you’re in the hospital ICU with this complication, the study may offer a targeted treatment strategy and careful monitoring.
Shanghai, Shanghai MunicipalityAges 4 weeks–18 years - NCT03720860Recruiting
Study inflammatory signals in sudden kidney injury in ICU
This study looks at substances related to inflammation to better understand sudden kidney problems in people who are very sick in the ICU. It may help improve how kidney injury is predicted and treated after severe illness or major events.
Uppsala, Uppsala CountyAges 18 years+ - NCT04178915Enrolling by invitation
Blood marker study to predict severe bacterial lung infection
This study looks at specific immune cells and how fats are transported in the blood to predict which people will have a severe bacterial infection (like pneumonia or sepsis). Your results may help doctors identify higher-risk patients earlier.
MinskAges 18–60 - NCT03992378Recruiting
Nerve stimulation to calm inflammation in sepsis
This trial tests a form of nerve stimulation to help control the body’s overactive inflammation and “autonomic” nervous system imbalance during sepsis. It may help stabilize blood pressure and reduce complications, depending on the cause of your symptoms.
Oklahoma City, OklahomaAges 18 years+ - NCT03334006RecruitingPhase 2
Tested special immune-targeting treatment after abdominal infection surgery
This Phase 2 study tests whether Pentaglobin®, a blood-product made from immune proteins, helps critically ill people with severe abdominal infection (peritonitis) after the infection source is surgically cleaned up. It targets patients with signs of strong inflammation and severe illness.
ViennaAges 18 years+
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Common questions
- Are there clinical trials for sepsis?
- Yes. Clin2 currently lists 267 recruiting sepsis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sepsis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sepsis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.