Clinical trials
Thoracic Radiotherapy clinical trials
Below are recruiting thoracic radiotherapy clinical trials, each written for real people, not researchers. We’re tracking 40 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07015892RecruitingPhase 3
Higher radiation dose for limited-stage small cell lung cancer
This trial tests a higher dose of radiation therapy for people with limited-stage small cell lung cancer (cancer that hasn't spread beyond the chest). It aims to see if the higher dose works better than the standard dose at controlling the cancer.
Salamanca, SalamancaAges 18 years+ - NCT06950073Recruiting
Second radiation treatment for lung cancer in the chest
This study tests whether giving a second course of radiation to the chest (called retreatment) can control lung cancer that has come back or a new cancer that started there. People who have already had radiation to their chest and are healthy enough for more may be eligible.
Aarhus, JutlandAges Any age - NCT05552846Recruiting
Radiation to the chest after chemo-immunotherapy for small cell lung cancer
This trial looks at whether giving additional targeted radiation to the chest can help people with extensive-stage small cell lung cancer after they finish standard chemo-immunotherapy. It may help control the cancer in the lung area and prevent it from coming back there.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06536868RecruitingPhase 2
Tislelizumab with chemo and radiation for extensive-stage small cell lung cancer
This trial tests a combination of an immunotherapy drug (tislelizumab) with chemotherapy and chest radiation for people with extensive-stage small cell lung cancer (SCLC) that has spread. The goal is to see if this combination helps shrink or control the cancer longer.
Jincheng, ShanxiAges 18–80 - NCT05349552Recruiting
Radiation for lung or chest cancers in specific locations
This trial studies how safe and effective a type of focused radiation called SBRT is for cancer tumors in certain chest locations. It’s meant for people whose tumor is small (up to 5 cm) and who don’t have widespread, uncontrolled spread.
Beijing, Beijing MunicipalityAges 18–80 - NCT06410300Recruiting
Heart and lung monitoring during lung cancer radiation and immunotherapy
This study monitors how the heart and lungs respond to radiation therapy combined with immunotherapy for locally advanced lung cancer. It aims to learn how well patients tolerate treatment and to detect early signs of side effects.
Columbia, MissouriAges 18 years+ - NCT06771518RecruitingPhase 2
Study combining chest radiation and immunotherapy for lung cancer
This study tests whether adding radiation to the chest area can improve the effectiveness of maintenance immunotherapy (atezolizumab) in patients with extensive-stage small cell lung cancer who have responded well to initial treatment.
Rome, RomeAges 18 years+ - NCT06596954Recruiting
Lymphocyte-sparing radiation for esophageal cancer
This trial tests a special type of radiation therapy that aims to spare your immune cells (lymphocytes) while treating esophageal cancer. It may help patients with locally advanced esophageal squamous cell carcinoma who are in good overall health.
Shanghai, ChinaAges 18–80 - NCT07037680RecruitingPhase 2
Radiation plus Anlotinib for advanced lung cancer
This trial tests a combination of radiation therapy and a targeted drug (Anlotinib) for people with a type of advanced lung cancer that cannot be treated with standard chemoradiation. It may help if your cancer has not spread to other parts of the body and you have not had certain prior treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07358676RecruitingPhase 2
Study of bemotuzumab plus chemo and anlotinib for advanced small cell lung cancer
This trial tests a combination of the targeted drug bemotuzumab, chemotherapy, and anlotinib (which blocks blood vessel growth) followed by radiation therapy for people with extensive-stage small cell lung cancer who haven't had treatment yet. The goal is to see if this approach helps control the cancer.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT05557552Recruiting
Chemo and immunotherapy plus chest radiation for stage III lung cancer
This trial studies a treatment plan that combines chemotherapy, immunotherapy, and radiation to the chest for people with unresectable stage III non-small-cell lung cancer (NSCLC). It may help by delivering anti-cancer drugs while also shrinking tumors with targeted radiation, especially for people who are not able to have the standard “chemo and radiation at the same time.”
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06865339RecruitingPhase 2
Radiation plus immunotherapy for advanced lung cancer
This trial tests whether adding two immunotherapy drugs (cemiplimab and fianlimab) to standard radiation and chemotherapy can help treat locally advanced non-small cell lung cancer that hasn't been treated before.
The Bronx, New YorkAges 18 years+ - NCT07314216RecruitingPhase 2
Firmonertinib plus radiation for stage III lung cancer with rare EGFR mutations
This trial tests whether combining the targeted pill firmonertinib with radiation therapy can help people with stage III non-small cell lung cancer that has certain rare EGFR mutations. It is for those whose cancer cannot be removed by surgery.
Changsha, HunanAges 18 years+ - NCT06262321RecruitingPhase 2
Chest Radiation for Advanced Lung Cancer at High Risk of Symptoms
This study tests whether giving radiation to tumors in the chest soon after starting systemic therapy can help prevent symptoms like pain, trouble breathing, or bleeding. It is for people with advanced non-small cell lung cancer that does not have certain gene changes and has high-risk tumors in the chest.
Rochester, New YorkAges 18 years+ - NCT06373497RecruitingEarly Phase 1
Heart artery health after chest radiation using PET scan
This study looks at how radiation therapy to the chest affects the arteries in your heart. It uses a special PET scan (with a safe radioactive tracer) to check for early signs of inflammation or plaque buildup, which can help doctors find ways to protect your heart during cancer treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT07050056RecruitingPhase 2
Immunotherapy plus radiation before lung cancer surgery
This study tests whether giving a combination of the immunotherapy drug tislelizumab and chest radiation before surgery can improve outcomes for people with early-stage, operable lung cancer. The goal is to find out if this approach helps shrink the tumor and makes surgery more effective.
Yangzhou, JiangsuAges 18–70 - NCT05651802Recruiting
Brain MRI follow-up with or without preventive scans in SCLC
This study tests whether adding a preventive brain procedure (PCI) to standard follow-up brain MRIs helps people with limited-stage small-cell lung cancer stay disease-free longer. It compares “MRI only” versus “MRI plus PCI” after the cancer has fully responded to initial treatment.
Guangzhou, GuangdongAges 18 years+ - NCT03978377Recruiting
Checks heart and lung effects after chest radiation
This study looks at how chest radiation treatment affects the heart and lungs in people with certain lung or esophagus cancers. It may help doctors better predict and prevent these side effects during curative (aimed at cure) radiotherapy.
LeuvenAges 18 years+ - NCT06354530RecruitingPhase 2/Phase 3
Study of pre-surgery therapy for advanced esophageal cancer
This trial tests a combination of drugs (anlotinib, immunotherapy, and chemotherapy) given before surgery for esophageal cancer that has not spread to other organs. The goal is to see if this approach shrinks the tumor and improves outcomes.
Chongqing, None SelectedAges 18–80 - NCT06361784Recruiting
Heart-Sparing Radiation for Stage 3 Lung Cancer
This study tests a new way of planning radiation therapy for stage 3 lung cancer. By carefully mapping the heart's structure, doctors aim to protect it from radiation and improve treatment safety.
MilanAges Any age - NCT06840704RecruitingPhase 3
Can immunonutrition reduce esophagitis during lung cancer radiation?
This trial tests if a special nutritional supplement (immunonutrition) can lower the risk of severe throat and chest irritation (esophagitis) caused by radiation therapy for lung cancer. You may qualify if you are about to start chest radiation and can eat normally.
Changsha, HunanAges 18 years+ - NCT06869239Recruiting
Predicting response to PD-L1 inhibitor after chemoradiotherapy for limited-stage small cell lung cancer
This study uses a blood test to see if it can predict how well the PD-L1 inhibitor (an immunotherapy drug) works after standard chemotherapy and radiation for limited-stage small cell lung cancer. It aims to find better ways to match treatment to patients.
Beijing, Beijing MunicipalityAges 18–75 - NCT06919874Recruiting
Yoga app for lung or esophageal cancer patients and caregivers
This study tests a mobile app that guides you and a family caregiver through a gentle yoga program while you go through radiation therapy for lung or esophageal cancer. The goal is to see if the app helps you both feel better during treatment.
Houston, TexasAges 18 years+ - NCT07669493Recruiting
Heart safety during chest radiation for cancer patients
This study looks at how chest radiation affects heart function and the immune system, and whether it is safe in people with lung, esophageal, breast, or thymus cancer who have not had chest radiation before.
Shijiazhuang, HebeiAges 18 years+
Hear when a new Thoracic Radiotherapy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for thoracic radiotherapy?
- Yes. Clin2 currently lists 40 recruiting thoracic radiotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a thoracic radiotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a thoracic radiotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.