Clinical trials
Transplant; Failure, Heart clinical trials
Below are recruiting transplant; failure, heart clinical trials, each written for real people, not researchers. We’re tracking 269 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07215715Recruiting
Heart ultrasound study for older adults with heart failure
This study uses a special ultrasound to measure heart stiffness in people 60 and older who have heart failure with preserved or mildly reduced pumping function, with or without a condition called ATTR amyloidosis (a protein buildup in the heart). It also includes healthy controls.
Boston, MassachusettsAges 60 years+ - NCT07217392Recruiting
Study on pacing the left bundle branch area of the heart
This study tests a new way to place a pacemaker lead in the left bundle branch area of the heart. It may help people who need a pacemaker to see if this approach is safe and works well.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT07273838RecruitingPhase 2
SGLT2 inhibitor for acute heart and kidney failure
This study tests whether a medicine called an SGLT2 inhibitor (which lowers blood sugar and helps the kidneys) can improve outcomes for people with acute heart failure and kidney problems. Participation involves taking the study drug or a placebo for a short time.
New Haven, ConnecticutAges 18–85 - NCT06299514Recruiting
Pacemaker and ablation for heart failure with atrial fibrillation
This trial tests if a pacemaker plus an ablation procedure can improve heart failure symptoms in people with atrial fibrillation. It is for those with moderate to severe heart failure who are already on the right medications.
Victoria, British ColumbiaAges 18 years+ - NCT07372196Recruiting
Left bundle branch pacing after myectomy for hypertrophic cardiomyopathy
This trial is testing a new way to pace the heart (left bundle branch pacing) for people with hypertrophic cardiomyopathy who still have a dangerous heart rhythm problem after myectomy surgery. It aims to see if this pacing can reduce the risk of sudden cardiac death.
Novosibirsk, Novosibirsk OblastAges 18–75 - NCT01790152Recruiting
Dexrazoxane study to monitor heart damage in cancer survivors
This study tests dexrazoxane (DRZ) to see how it affects blood and heart-related “biomarkers,” or measurable signs of heart damage, after cancer treatment. It mainly targets survivors who may be at risk for cardiomyopathy (heart muscle weakness) or related heart failure.
Birmingham, AlabamaAges Any age - NCT03238690Recruiting
LVAD conditioning to help your heart recover
This study looks at an approach called “conditioning” using your LVAD (a heart pump) while you wait for a transplant. It aims to see whether your heart muscle may recover better during planned changes in support.
Salt Lake City, UtahAges 18 years+ - NCT02683681Enrolling by invitation
Create a heart tissue and blood sample registry
This study collects blood and/or heart tissue samples from certain people getting heart procedures or with a long-term heart pump. The goal is to store these samples for future research that may improve care for heart failure.
Ages 18 years+ - NCT07413198Recruiting
Combined home and clinic exercise coaching for heart failure
This trial tests a program that combines home-based and clinic-based exercise coaching to help people with heart failure get more active. It aims to improve health and quality of life.
Winston-Salem, North CarolinaAges 55 years+ - NCT06241430Recruiting
CardioClip study: testing a new valve repair for leaky heart valve
This study tests a new clip procedure (CardioClip) to repair a leaky mitral valve in people with heart failure. It aims to see if the clip can improve symptoms and heart function.
New York, New YorkAges 18–90 - NCT07393009Recruiting
Study of a new left bundle branch area pacing system
This study tests a new type of pacemaker system that delivers pacing to the left side of the heart through a lead placed deep in the wall between the lower chambers. The goal is to see if this approach works well for people who need a pacemaker or CRT.
AdelaideAges 18 years+ - NCT07489105Recruiting
Yoga for better thinking with heart failure
This trial tests if a yoga program can help improve memory and thinking in people with heart failure. It's designed for adults 55 and older who are not already doing yoga and are able to take part in gentle physical activity.
Auburn, AlabamaAges 55 years+ - NCT07632586Recruiting
First-in-Human Heart Pump Implant Study
This trial tests a new tiny heart pump called the Icoms Flowmaker for patients with severe heart failure who cannot have a standard heart pump. The device may help your heart pump blood better and improve your ability to do daily activities.
PragueAges 18–80 - NCT06434168Enrolling by invitation
Yoga for brain health in heart failure
This study tests whether yoga can help improve memory and thinking for people with heart failure who also have mild memory problems. It aims to see if a gentle yoga program can support both heart and brain health.
Auburn, AlabamaAges 55–70 - NCT03836482Recruiting
SCD test for people with heart and kidney failure awaiting LVAD
This study looks at whether a treatment called SCD is safe and workable in people who have worsening heart failure along with kidney problems, and who are waiting to get an LVAD (a mechanical heart pump). It is mainly a feasibility study, meaning the researchers want to see if this approach can be used in real hospital care and monitor effects on key health measures.
Ann Arbor, MichiganAges 18 years+ - NCT06615492Recruiting
Lung transplant study: comparing two ECMO methods
This study compares two ways of using a heart-lung machine (ECMO) during lung transplant surgery. The goal is to see if using ECMO only when needed works as well as using it for everyone. This could help reduce risks and improve recovery.
Edmonton, AlbertaAges 18 years+ - NCT07053462RecruitingPhase 1/Phase 2
Gene-edited kidney transplant to lower rejection risk
This trial tests a specially edited donor kidney designed to reduce the chance of rejection, especially for people with high sensitivity to donor kidneys. If it works, it could make more kidneys available for those who have a hard time finding a match.
Beijing, ChangpingAges 16–85 - NCT07053488RecruitingPhase 1/Phase 2
Gene-edited liver transplant to lower rejection risk
This trial tests a liver transplant using a donor organ that has been gene-edited to reduce the risk of rejection. It may help people who need a liver transplant and are not a perfect tissue match with their donor.
Beijing, ChangpingAges 16–85 - NCT03394365RecruitingPhase 3
Tabelecleucel for EBV-related lymphoma after transplant treatment failure
This trial tests tabelecleucel, an immune therapy, for people whose EBV-associated post-transplant lymphoproliferative disease (PTLD) did not respond to rituximab and/or chemotherapy. It may help your immune system better control EBV-driven lymphoma after a transplant.
Duarte, CaliforniaAges Any age - NCT01893710Recruiting
Collecting children and adult belly fluid and tissue for kidney care research
This study collects samples from the belly (related to the peritoneal lining) to build a “biobank” for future research. It may help patients and families by improving understanding of kidney disease and kidney dialysis-related health issues.
Birmingham, AlabamaAges 1 day–90 years - NCT05823376Recruiting
Avatrombopag to help platelets recover after bone marrow transplant
This trial studies whether avatrombopag can help your platelet count recover after a bone marrow transplant from an unrelated donor (UCBT) in certain bone marrow failure diseases. If platelets recover better, it may reduce risks related to low platelets after transplant.
Hefei, AnhuiAges 12 years+ - NCT06398457RecruitingEarly Phase 1
Darzalex Before Stem Cell Transplant for High-Risk Graft Failure
This trial tests giving a drug called Darzalex Faspro before the usual desensitization and a stem cell transplant for people at high risk of graft failure due to donor-specific antibodies. The goal is to prevent the transplant from failing.
Baltimore, MarylandAges 18 years+ - NCT03818334RecruitingPhase 2/Phase 3
Cyclophosphamide after transplant for blood cancer without sibling donor
This trial studies giving cyclophosphamide after a stem cell transplant when there is no matched sibling donor, but a well-matched unrelated donor is available. It aims to improve outcomes for people with blood cancers undergoing this transplant.
São Paulo, São PauloAges 1–75 - NCT01174108RecruitingPhase 2
Stem cell transplant with donor T-cells for severe bone marrow failure
This Phase 2 study tests a specific type of donor stem cell transplant for severe bone marrow failure conditions, aiming to improve cure rates while reducing transplant risks. It includes people with diseases like severe aplastic anemia and certain bone marrow disorders, especially when standard transplant plans feel too risky.
Baltimore, MarylandAges 4–80
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Common questions
- Are there clinical trials for transplant; failure, heart?
- Yes. Clin2 currently lists 269 recruiting transplant; failure, heart studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a transplant; failure, heart trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a transplant; failure, heart trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.