Clinical trials
Valvular Heart Disease Patients clinical trials
Below are recruiting valvular heart disease patients clinical trials, each written for real people, not researchers. We’re tracking 191 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07657676RecruitingPhase 4
Study of mazdutide for heart artery plaque in people who are overweight
This study tests whether mazdutide, a medicine that may help with weight and blood sugar, can reduce plaque buildup in the heart's arteries. It is for people who are overweight or obese and have some narrowing in their heart arteries but do not need immediate procedures like stents.
Beijing, Beijing MunicipalityAges 18 years+ - NCT03854071Recruiting
Heart and health MRI testing in healthy people or patients
This study uses MRI (a scanning test) to develop new ways to measure heart function in both healthy volunteers and people with suspected or known heart disease. It may help researchers create better heart tests that could improve future diagnosis and monitoring.
Sheffield, EnglandAges 20–80 - NCT06024746RecruitingPhase 3
Finerenone plus SGLT2i for hospitalized heart failure
This trial tests whether adding two heart medicines together (finerenone and an SGLT2 inhibitor) helps people who are in the hospital for heart failure recover better. It may be an option for you if you are currently hospitalized and your heart stress markers are high.
Fairhope, AlabamaAges 18 years+ - NCT06952374Recruiting
Shockwave balloon for severe mitral valve calcium
This trial tests a special balloon (Shockwave) to treat severe calcium buildup in the mitral valve. It may help people with tight valve opening who cannot have standard surgery.
Shatin, New TerritoriesAges 18 years+ - NCT05679024RecruitingPhase 3
Apixaban to prevent stroke in atrial fibrillation and kidney failure
This trial tests apixaban (a blood thinner) to prevent stroke in people with atrial fibrillation or atrial flutter who have very poor kidney function or are on dialysis. If you qualify, you may help researchers find a safer way to lower stroke risk for this higher-risk group.
HelsinkiAges 18 years+ - NCT06036615Recruiting
Exercise training for frailty and fall risk in heart failure
This trial tests whether a supervised exercise program can reduce frailty and fall risk in people with chronic heart failure, and what happens when training stops. It may help you feel stronger and more stable.
Thessaloniki, ThermiAges 18–100 - NCT05392764RecruitingPhase 3
SGLT2 medicine for high-risk people after sudden worsening heart failure
This Phase 3 trial tests whether starting an SGLT2 inhibitor early in the hospital can improve outcomes for people at high risk after acute (sudden) heart failure. If you qualify, you would be randomized to receive the study medicine or standard care, started within 12 hours of admission.
Anjo, Aichi-kenAges 20 years+ - NCT06128980RecruitingPhase 2/Phase 3
Stopping heart meds after recovery from fast heartbeat damage
This trial tests if patients whose heart function returned to normal after treating a fast heartbeat can safely stop their heart failure medications. It aims to see if treatment can be withdrawn without the heart problems coming back.
CopenhagenAges 18 years+ - NCT06196086Recruiting
Measuring heart stiffness in heart failure with normal pumping
This study uses a special ultrasound technique to check how stiff the heart muscle is in people with heart failure who have a normal pumping ability (HFpEF). It aims to better understand heart stiffness to help diagnose and manage this condition.
Jinan, ShandongAges 18–80 - NCT05609097Recruiting
Exercise program study for older adults with weaker heart pumping
This study tests a new exercise program for people over 65 with heart failure where the heart pumps less efficiently. The goal is to see if tailored exercise is safe and helpful for breathing, energy, and daily function.
Charlottesville, VirginiaAges 65 years+ - NCT06307652RecruitingPhase 3
Testing a new heart failure and kidney treatment combo
This study tests a new combination of two medicines (balcinrenone and dapagliflozin) for people with heart failure and reduced kidney function. The goal is to see if this combination helps improve heart and kidney health better than current treatments.
Alexander City, AlabamaAges 18–130 - NCT05448833Recruiting
Testing a wireless sensor to monitor left heart pressure
This study tests whether a small wireless sensor can safely measure and track pressure in the left upper heart chamber in people with advanced chronic heart failure. It may help the care team better understand pressure changes that are linked to fluid buildup and symptoms, alongside your usual heart medicines.
Petah TikvaAges 22–88 - NCT07107919Recruiting
Imaging heart and kidney health in chronic kidney disease
This study uses advanced imaging (PET/MRI) to look at how kidney disease affects the heart and blood vessels. It may help doctors better understand and treat chronic kidney disease.
Qingdao, ShandongAges 18–80 - NCT05255172Enrolling by invitation
Exercise program for heart failure with preserved or reduced pumping
This trial tests whether a structured exercise program can help people with heart failure. It focuses on people who are currently not very active, aiming to improve symptoms and heart/fitness measures safely.
LundAges 50–90 - NCT05508256RecruitingPhase 4
Ablation for atrial fibrillation in heart failure with preserved function
This trial tests whether a catheter procedure that treats atrial fibrillation works better than standard care for people with heart failure with preserved ejection fraction. It aims to improve heart rhythm symptoms and overall outcomes compared with conventional treatment.
BerlinAges 18 years+ - NCT05465031RecruitingPhase 4
Testing heart-protection medicine during breast cancer treatment
This trial tests sacubitril/valsartan to help prevent heart weakness (cardiotoxicity) caused by breast cancer treatments like anthracyclines and/or anti-HER2 drugs. If you qualify, you may be offered this heart-protection medicine while your cancer is treated.
Opole, Opole VoivodeshipAges 18 years+ - NCT07245069RecruitingPhase 2
Can dapagliflozin protect the heart during breast cancer chemo?
This trial tests if the drug dapagliflozin can prevent heart damage caused by anthracycline chemotherapy in breast cancer patients. It aims to see if taking the drug during chemo helps keep your heart healthy.
LjubljanaAges 18 years+ - NCT07130994Recruiting
Testing a new less invasive mitral valve replacement (SATURN)
This trial tests a new, less invasive device called the SATURN system to replace a severely leaky mitral heart valve without open-heart surgery. It is for people who are too high-risk for traditional surgery and are willing to take blood thinners.
Los Angeles, CaliforniaAges 18 years+ - NCT06891456Recruiting
Pulsed field ablation for ventricular tachycardia after heart attack
This trial tests a new type of energy (pulsed field ablation) to treat a fast heart rhythm called ventricular tachycardia that happens after a heart attack. The goal is to stop the dangerous rhythm without damaging nearby healthy tissue.
Cleveland, OhioAges 18 years+ - NCT06854458Recruiting
Stress heart MRI for better diagnosis of heart artery disease
This study uses a special stress heart MRI to measure blood flow and find blockages in the arteries that supply your heart. It is for people with chest pain or abnormal EKG results who have risk factors for heart disease, to help doctors diagnose and treat coronary artery disease more accurately.
San Francisco, CaliforniaAges 35–85 - NCT06145035RecruitingPhase 2
Stem cells from cord blood for heart failure
This trial tests whether stem cells from donated umbilical cord blood can improve heart function in people with heart failure caused by blocked arteries. You'll receive one or more infusions of these cells through a vein.
Miami, FloridaAges 21–85 - NCT05700617RecruitingEarly Phase 1
Testing cardiac pumping strength in cardiogenic shock
This early study looks at how well the heart is pumping in people with cardiogenic shock, using measurements taken during a right-heart catheter (a small pressure-monitoring test). It may help doctors better assess heart function and guide next-step treatments like LVAD, heart transplant, or valve surgery.
Chicago, IllinoisAges 18 years+ - NCT03563417Recruiting
CTO treatment vs medicines after heart scan
This trial studies whether opening a blocked coronary artery (a CTO) helps people more than staying on the best available heart medicines after an initial 3-month treatment period. It uses heart imaging to confirm there is reduced blood flow in the area supplied by the blockage.
Aarhus NAges 18 years+ - NCT06427343RecruitingPhase 4
IV iron: low dose vs high dose for heart failure with low iron
This study compares two different doses of IV iron (low vs high) to see which works better for people with heart failure and low iron levels. It may help you feel less tired and breathe easier.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for valvular heart disease patients?
- Yes. Clin2 currently lists 191 recruiting valvular heart disease patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a valvular heart disease patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a valvular heart disease patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.