Clinical trials
Weaning clinical trials
Below are recruiting weaning clinical trials, each written for real people, not researchers. We’re tracking 86 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07105202RecruitingPhase 4
Shorter weaning from ventilator with levosimendan
This study tests if a heart medication called levosimendan helps people get off the breathing machine (ventilator) faster. It's for people who have been on a ventilator for more than 48 hours and have already tried and failed to breathe on their own.
Arnhem, GelderlandAges 18 years+ - NCT07709182Recruiting
Guided breathing machine settings for weaning off ventilation
This trial compares two ways of adjusting the breathing machine to help patients come off it more smoothly. It uses a special measurement (airway occlusion pressure) to guide settings, which may help you breathe on your own faster.
Tanta, Al GharbiaAges 21 years+ - NCT07455214Recruiting
Heart rate variability and breathing trial success in ventilated patients
This study looks at whether heart rate patterns can help predict if a person on a breathing machine is ready to breathe on their own. It may help doctors decide the best time to try removing the breathing tube.
New Taipei CityAges 18–85 - NCT06464224Recruiting
Breathing effort patterns in patients coming off the ventilator
This study observes how your breathing effort changes as doctors try to remove you from the breathing machine (ventilator). It helps understand why some patients have trouble breathing on their own after being on the ventilator.
Rio de JaneiroAges 18 years+ - NCT06424314Recruiting
Trial on why some patients fail to come off a ventilator
This trial is studying why some people have trouble coming off a breathing machine (ventilator). It's for patients who've been on a ventilator for at least 2 days and don't have certain other conditions.
Guangzhou, GuangdongAges 18 years+ - NCT06321848Recruiting
Ultrasound to guide weaning from a breathing machine
This trial uses ultrasound pictures of the heart, lungs, and diaphragm (a muscle that helps you breathe) to help doctors decide when to take a patient off a breathing machine after surgery. It may help make the weaning process safer and more personalized.
HanoiAges 18 years+ - NCT05990348Recruiting
Comparing two breathing support methods for weaning from ventilator
This study compares two ways of helping patients breathe on a ventilator after a failed attempt to come off the machine. It looks at how the diaphragm and rib muscles work during each method to find the best approach for weaning.
RomeAges 18 years+ - NCT06104956Recruiting
Weaning from high-flow oxygen therapy in the ICU
This trial is testing a way to safely reduce high-flow oxygen therapy for patients in the ICU who have low oxygen levels. It might help find the right time to stop this treatment.
BloisAges 18–90 - NCT06525753Recruiting
Weaning from IV nutrition in children with intestinal failure
This study looks at children who have stopped needing IV nutrition (parenteral nutrition) for at least a year after having intestinal failure. It aims to understand their long-term health and growth.
Toronto, OntarioAges birth–18 years - NCT06754670Recruiting
How low phosphate affects breathing after ventilator use
This study looks at how low phosphate levels in the blood affect your ability to breathe on your own when coming off a ventilator. If you are already getting better and ready to start breathing without the machine, the results may help doctors understand and manage your recovery better.
BeijingAges 18 years+ - NCT06839846Recruiting
Survey of weaning methods in babies
This survey asks parents of babies aged 4 to 18 months about how they stopped breastfeeding or bottle-feeding (weaning). It helps doctors understand different weaning methods used by families in Italy.
Imola, BolognaAges Any age - NCT06867354Recruiting
Breathing difficulty in obese patients during weaning from ventilator
This study looks at how often obese patients have trouble breathing when doctors try to remove the breathing tube (weaning) in the ICU. The goal is to understand what causes this and how it affects recovery.
Paris, ParisAges 18 years+ - NCT07091175RecruitingPhase 2
Dupilumab for nephrotic syndrome in children
This trial tests if dupilumab can help children with nephrotic syndrome who still have relapses despite standard treatments. It aims to find a better way to control the disease and reduce steroid side effects.
Singapore, SingaporeAges 6–18 - NCT07098611Recruiting
New tool to predict readiness for breathing tube removal
This study tests a new scoring tool to help doctors decide when a patient on a breathing machine is ready to have the tube removed safely. It is for patients who are currently in the process of being weaned off the ventilator.
Punta ArenasAges 18–89 - NCT07590362Recruiting
Testing breathing readiness measures in ventilated COPD patients
This study compares two methods of measuring whether patients with COPD who are on breathing machines are ready to breathe on their own. The goal is to find the best way to predict which patients can successfully come off the ventilator.
Sohag, Sohag GovernorateAges 18 years+ - NCT07771101Recruiting
Using a pain monitor to time breathing-tube removal
This study tests whether a special monitor can help doctors know when it's safe to take a breathing tube out after surgery in the ICU. The monitor looks at pain signals, and the goal is to make the process of breathing on your own again more comfortable.
SeoulAges 18 years+ - NCT07761468Enrolling by invitation
Standardized medication dosing for ICU patients on ventilators
This study is testing a standardized way to adjust a medication used to help people on ventilators in the ICU. It aims to see if a more consistent dosing approach can help patients breathe better and possibly come off the ventilator sooner.
Querétaro City, QuerétaroAges 18 years+ - NCT06450678Recruiting
Can a physiotherapy test predict breathing tube removal success?
This study checks if a quick physical therapy exam can predict whether a person will need the breathing machine again after it is removed. It is for adults who have been on a ventilator for more than two days and have already shown they can breathe on their own for a short time.
ParisAges 18 years+ - NCT07750288Recruiting
Understanding breathing difficulty in children with lung injury
This study looks at how severe breathing difficulty (dyspnea) affects the recovery of children with a lung condition called acute respiratory distress syndrome (ARDS). It aims to improve care by tracking symptoms over time.
SantiagoAges 1 month–18 years - NCT07066605Recruiting
Dexmedetomidine for agitation during breathing tube removal
This trial tests whether a sedative called dexmedetomidine can reduce agitation in ICU patients when they are being weaned off a breathing tube. If you experience restlessness or agitation during the weaning process, this medication might help you stay calm.
SohagAges 19 years+ - NCT06033144Recruiting
Tapia's syndrome study in breathing recovery unit
This study looks at how common Tapia's syndrome (a rare nerve problem after breathing tube use) is in patients recovering from long-term breathing support. If you've had a breathing tube for more than 48 hours, you may be able to help researchers learn more about this condition.
Férolles-Attilly, Seine-et-MarneAges 18 years+ - NCT05710432Recruiting
Exercises to help breathing during ventilator weaning
This study tests whether specific neck and breathing muscle exercises during ventilator weaning can help people breathe more effectively and safely come off the ventilator. It may help patients who have already had trouble with prior weaning attempts.
Toronto, OntarioAges 16 years+ - NCT05134467Recruiting
Protocol-based weaning from the ventilator in ICU patients
This study looks at a step-by-step plan to help patients come off the breathing machine (mechanical ventilator) and checks how well it works. If you’re an ICU patient on the ventilator for at least two days, you may be eligible to follow their protocol.
SeoulAges 19–99 - NCT07054983Enrolling by invitation
Parent interviews on tube weaning experiences
This study interviews parents about their child's tube weaning process to understand what helps or makes it harder. Your insights could help improve support for other families.
Kansas City, MissouriAges 18 years+
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Common questions
- Are there clinical trials for weaning?
- Yes. Clin2 currently lists 86 recruiting weaning studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a weaning trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a weaning trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.