Clinical trials
Weaning clinical trials
Below are recruiting weaning clinical trials, each written for real people, not researchers. We’re tracking 80 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07445035Recruiting
Robotic leg brace to help walking while on a breathing machine
This study tests whether walking with a robotic leg brace (exoskeleton) can help people who are on a breathing machine get better faster. It is for adults in the intensive care unit who can sit, stand with help, and have no major leg or heart problems.
New Taipei CityAges 45–65 - NCT07432191Recruiting
Testing a new ventilator for safe breathing support
This study tests a new breathing machine (INBENTUS VERSATILE ventilator) for people who need help breathing. It checks if the machine is safe and works well for patients who need a ventilator and then slowly come off it.
MurciaAges 18 years+ - NCT07390903Recruiting
Heart function test for difficult bypass weaning
This trial studies whether a heart ultrasound test called GLS can help predict complications when patients are taken off the heart-lung machine after heart surgery. It aims to improve management for better outcomes.
RomeAges 18 years+ - NCT07372664Recruiting
Testing a weaning readiness tool for ventilated patients
This study looks at how well a tool (VVI) can predict if patients on a breathing machine are ready to start breathing on their own. It may help doctors decide the best time to begin the weaning process.
LarissaAges 18 years+ - NCT07363902Recruiting
Electrical muscle stimulation study for breathing support
This study tests a new device that uses mild electrical pulses to strengthen the muscles used for breathing in people who are on a ventilator. It aims to help them recover faster.
Barcelona, BarcelonaAges 18 years+ - NCT07256821Recruiting
Finding the best breathing muscle training dose in the ICU
This trial tests different amounts of inspiratory muscle training (IMT) for patients who have a tracheostomy tube and are on a breathing machine in the intensive care unit. Researchers want to find the dose that helps most with recovery.
MarlowAges 18 years+ - NCT07177183Recruiting
Low creatinine as a sign of longer breathing tube use
This study looks at whether low blood creatinine levels can help predict which patients will need a breathing machine for a long time or have trouble coming off it. If you are under 18 and in a post-ICU care unit, you may be able to join.
BrnoAges 18 years+ - NCT07143695Recruiting
Chest muscle ultrasound to guide breathing machine weaning
This study uses an ultrasound to measure how well a chest muscle moves when you try to breathe on your own. It may help doctors decide if you are ready to come off the breathing machine.
Cairo, Giza GovernorateAges 18–65 - NCT07130123Recruiting
Endotracheal suction during extubation in the ICU
This study compares different methods of suctioning the breathing tube during extubation (removal of the tube) in patients who have been on a ventilator for more than 48 hours. It aims to find the best way to clear the airway while taking the tube out.
Orléans, LoiretAges 18 years+ - NCT05710432Recruiting
Exercises to help breathing during ventilator weaning
This study tests whether specific neck and breathing muscle exercises during ventilator weaning can help people breathe more effectively and safely come off the ventilator. It may help patients who have already had trouble with prior weaning attempts.
Toronto, OntarioAges 16 years+ - NCT06716463Recruiting
Predicting breathing support failure with wearable monitoring
This study tests if a wearable chest monitor can predict when breathing support (like a mask or nasal prongs) might stop working, so doctors can act faster. It is for hospital patients who need help breathing but are not on a breathing tube.
Toronto, OntarioAges 18 years+ - NCT07066605Recruiting
Dexmedetomidine for agitation during breathing tube removal
This trial tests whether a sedative called dexmedetomidine can reduce agitation in ICU patients when they are being weaned off a breathing tube. If you experience restlessness or agitation during the weaning process, this medication might help you stay calm.
SohagAges 19 years+ - NCT07054983Enrolling by invitation
Parent interviews on tube weaning experiences
This study interviews parents about their child's tube weaning process to understand what helps or makes it harder. Your insights could help improve support for other families.
Kansas City, MissouriAges 18 years+ - NCT07022704Recruiting
Doxapram to help COPD patients breathe easier off the ventilator
This trial tests if the drug doxapram can improve diaphragm movement in COPD patients who are being taken off a ventilator during a breathing trial. It aims to make the transition smoother and more successful.
Cairo, Cairo GovernorateAges 20–65 - NCT07003672Recruiting
Weaning from ventilator: a lung measurement study
This study looks at people who have a tracheostomy and have been on a breathing machine for at least two weeks. Researchers want to see if certain lung measurements can help predict how easy or hard it will be to come off the ventilator.
TaipeiAges 20 years+ - NCT06876415Recruiting
Comparing two ways to wean patients off ECMO
This study compares two methods for removing patients from a breathing machine called ECMO. It aims to find which approach works better and is safer.
LyonAges 18 years+ - NCT06547463Recruiting
Nasal airflow and sleep in tracheostomy patients
This study looks at how breathing through your nose affects sleep quality for patients with a tracheostomy who are on a ventilator at night. It involves a sleep test to measure your sleep patterns and breathing, which could help improve your care.
Paris, ParisAges 18 years+ - NCT06835842Recruiting
Rib mobilization for pneumonia patients on a ventilator
This study tests whether a gentle rib movement technique (called rib mobilization) can help people with pneumonia who are on a breathing machine get ready to breathe on their own. It aims to see if this therapy makes it easier to wean off the ventilator.
CairoAges 40–50 - NCT06832163Recruiting
Smart weaning from inhaled nitric oxide for newborns with PPHN
This trial tests a new, smart way to slowly reduce (wean) the inhaled nitric oxide gas that helps babies with a serious lung condition called PPHN. If your baby is already responding well to iNO and needs it for at least 24 hours, this study might help make the weaning process safer and more effective.
ShanghaiAges Any age - NCT06630013Recruiting
Ultrasound test for swallowing problems in patients with a tracheostomy
This study tests if a new ultrasound score can help diagnose swallowing disorders in patients who are difficult to wean from a breathing tube and have a tracheostomy. It may help doctors better assess swallowing without more invasive tests.
Beuvry, BeuvryAges 18 years+ - NCT06579157Recruiting
Using pressure-sensing mattresses to help newborns breathe on their own
This trial tests whether a special mattress that senses breathing movements can help doctors decide when to remove breathing support from newborns. It may reduce the time babies need a breathing machine.
New Taipei CityAges Up to 1 year - NCT06561295Recruiting
Best time for breathing trials in ventilated patients
This study looks at the best time to do a breathing trial for patients on a ventilator. It helps doctors decide when to start testing if you can breathe on your own so you can come off the ventilator sooner.
Chicago, IllinoisAges 21 years+ - NCT06450678Recruiting
Can a physiotherapy test predict breathing tube removal success?
This study checks if a quick physical therapy exam can predict whether a person will need the breathing machine again after it is removed. It is for adults who have been on a ventilator for more than two days and have already shown they can breathe on their own for a short time.
ParisAges 18 years+ - NCT06319248RecruitingPhase 2
Midodrine to treat sepsis and reduce IV vasopressors
This trial tests if the oral medication midodrine can help wean patients with sepsis off IV vasopressors faster, potentially reducing ICU stays and complications.
Scottsdale, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for weaning?
- Yes. Clin2 currently lists 80 recruiting weaning studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a weaning trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a weaning trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.