Clinical trials
Weaning clinical trials
Below are recruiting weaning clinical trials, each written for real people, not researchers. We’re tracking 86 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07722260Recruiting
Cough assistance for breathing tube weaning
This study tests whether special cough-aid techniques help adults on breathing tubes get off the ventilator faster. It may be an option for patients who need extra help coughing while they recover.
DamanhūrAges 18 years+ - NCT06142474RecruitingPhase 3
SGLT2 inhibitors for heart failure patients during ventilator weaning
This trial tests a heart failure medication (SGLT2 inhibitor) to help people with heart failure who are on a breathing machine (ventilator) get better and come off the machine faster. It is for patients with a specific type of heart failure where the heart pumps weakly (EF ≤ 40%).
TaipeiAges 20 years+ - NCT05886803Recruiting
Predicting breathing test success in the ICU
This study uses data from your hospital records to see if a machine learning tool can predict whether a patient will succeed when doctors try to remove their breathing tube during a test of their own breathing.
NiceAges Any age - NCT07372664Recruiting
Testing a weaning readiness tool for ventilated patients
This study looks at how well a tool (VVI) can predict if patients on a breathing machine are ready to start breathing on their own. It may help doctors decide the best time to begin the weaning process.
LarissaAges 18 years+ - NCT07363902Recruiting
Electrical muscle stimulation study for breathing support
This study tests a new device that uses mild electrical pulses to strengthen the muscles used for breathing in people who are on a ventilator. It aims to help them recover faster.
Barcelona, BarcelonaAges 18 years+ - NCT06547463Recruiting
Nasal airflow and sleep in tracheostomy patients
This study looks at how breathing through your nose affects sleep quality for patients with a tracheostomy who are on a ventilator at night. It involves a sleep test to measure your sleep patterns and breathing, which could help improve your care.
Paris, ParisAges 18 years+ - NCT07630662Recruiting
Breathing Muscle Function and Ventilator Weaning Success
This study looks at whether testing the strength and function of your breathing muscles (diaphragm and chest wall muscles) can predict whether you're ready to come off a ventilator (breathing machine). The goal is to help doctors make better decisions about when patients are ready to breathe on their own.
CairoAges 18 years+ - NCT07130123Recruiting
Endotracheal suction during extubation in the ICU
This study compares different methods of suctioning the breathing tube during extubation (removal of the tube) in patients who have been on a ventilator for more than 48 hours. It aims to find the best way to clear the airway while taking the tube out.
Orléans, LoiretAges 18 years+ - NCT07445035Recruiting
Robotic leg brace to help walking while on a breathing machine
This study tests whether walking with a robotic leg brace (exoskeleton) can help people who are on a breathing machine get better faster. It is for adults in the intensive care unit who can sit, stand with help, and have no major leg or heart problems.
New Taipei CityAges 45–65 - NCT06627686Recruiting
Predicting successful breathing tube removal in brain injury patients
This study tests if simple breathing tests can predict whether a patient with a traumatic brain injury will successfully breathe on their own after a breathing tube is removed. The goal is to make the removal process safer.
Tanta, MahalaAges 18–65 - NCT07467265Recruiting
Testing a breathing test to safely remove ventilators
This study is testing a simple way to measure how well you breathe on your own when coming off a ventilator in the ICU. It helps doctors decide the best time to safely remove the breathing tube.
Cairo, AbbasiaAges 22 years+ - NCT07003672Recruiting
Weaning from ventilator: a lung measurement study
This study looks at people who have a tracheostomy and have been on a breathing machine for at least two weeks. Researchers want to see if certain lung measurements can help predict how easy or hard it will be to come off the ventilator.
TaipeiAges 20 years+ - NCT07710469Enrolling by invitation
Weighted blanket for comfort during vent weaning
This trial is testing whether a special weighted blanket can help you feel more calm and comfortable as doctors slowly reduce the support from your breathing machine. It's for people who are on a ventilator and ready to start the weaning process.
Boston, MassachusettsAges 18 years+ - NCT07256821Recruiting
Finding the best breathing muscle training dose in the ICU
This trial tests different amounts of inspiratory muscle training (IMT) for patients who have a tracheostomy tube and are on a breathing machine in the intensive care unit. Researchers want to find the dose that helps most with recovery.
MarlowAges 18 years+ - NCT06521515Recruiting
Lung ultrasound to predict weaning success
This study uses a lung ultrasound to predict which patients can safely come off a breathing machine. It's for older adults or those with heart/lung conditions who are at higher risk of needing the tube again.
Shanghai, Shanghai MunicipalityAges 18–100 - NCT07177183Recruiting
Low creatinine as a sign of longer breathing tube use
This study looks at whether low blood creatinine levels can help predict which patients will need a breathing machine for a long time or have trouble coming off it. If you are under 18 and in a post-ICU care unit, you may be able to join.
BrnoAges 18 years+ - NCT04080440Recruiting
Checking readiness to remove the breathing tube after brain injury
This study looks at how to judge when it is safe to remove the breathing tube in people in the ICU after a brain injury. It may help improve timing and safety of extubation, when supported by a breathing trial and clinical stability.
AngersAges 18–75 - NCT05117450Recruiting
Compare two dialysis membranes to adjust heparin use
This study compares two dialysis membranes while using a reduced “weaning” plan for the blood thinner heparin during hemodialysis. It aims to see which membrane works better and safely during routine chronic dialysis.
ReimsAges 18 years+ - NCT05226247Recruiting
Check whether careful weaning prevents lung fluid buildup
This study looks at people on a breathing machine for more than 48 hours who are starting a “spontaneous breathing trial,” a test used to see if they can breathe on their own. It focuses on those at higher risk of “weaning-induced pulmonary edema,” meaning fluid can collect in the lungs during the weaning process.
DijonAges 18 years+ - NCT05687292Recruiting
Decision tool to shorten breathing machine time in children
This study tests whether a computer “decision support” tool can help doctors safely reduce how long a child stays on a breathing machine after heart surgery. It may help children get off mechanical ventilation sooner and recover faster.
Boston, MassachusettsAges 1 day–12 years - NCT05710705Recruiting
Bioimpedance monitoring in belly-flap breast reconstruction
This study tests a method called bioimpedance to monitor blood flow in the transplanted belly tissue during breast reconstruction surgery. It may help doctors know when the blood supply is stable, which could lead to safer recovery.
AmiensAges 18 years+ - NCT06009731Recruiting
Diaphragm ultrasound during breathing trial
This study uses a special ultrasound technique to look at how your diaphragm (the main breathing muscle) moves while you try breathing on your own. It may help doctors better understand when patients are ready to come off the breathing machine.
AmiensAges 18 years+ - NCT06319248RecruitingPhase 2
Midodrine to treat sepsis and reduce IV vasopressors
This trial tests if the oral medication midodrine can help wean patients with sepsis off IV vasopressors faster, potentially reducing ICU stays and complications.
Scottsdale, ArizonaAges 18 years+ - NCT06525818Recruiting
E.A.T. study: Helping kids with feeding tubes eat by mouth
This study tests a new program to help children under 3 who have both a feeding tube and a tracheostomy start eating by mouth. The program provides support and training for families at home.
Chicago, IllinoisAges Up to 3 years
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Common questions
- Are there clinical trials for weaning?
- Yes. Clin2 currently lists 86 recruiting weaning studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a weaning trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a weaning trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.