Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT06718296Recruiting
Photographic Shoulder Pain Scale Study
This study is creating a new way to measure shoulder pain using pictures. It is for people who have had shoulder pain for more than 3 months, whether from an injury or other causes.
IstanbulAges 18–64 - NCT06718569Recruiting
Pain in Inflammatory Joint Diseases
This study looks at pain in people with inflammatory joint diseases. It aims to understand how pain changes when you start or switch to a newer type of arthritis medication.
OsloAges 18 years+ - NCT06719037Recruiting
Comparing two spine surgeries for lower back narrowing
This study compares two different surgical techniques – one using a small camera (endoscopic discectomy) and the other a traditional open approach (microdiscectomy) – to treat narrowing in the lower spine. It helps find which method may be better for relieving pain and improving function.
Jinan, ShandongAges 18–80 - NCT06720142Recruiting
Magnesium bone filler study after tumor or trauma surgery
This study looks at how well a magnesium-based bone filler (Mg OSTEOCRETE) works for people who need it after bone tumor removal, to fix loose implants, or to help heal bone from injuries. Researchers want to track outcomes to see how helpful it is.
Boston, MassachusettsAges 18 years+ - NCT06720272Recruiting
School program to prevent rheumatic heart disease
This study tests whether a program in schools can help prevent rheumatic heart disease in children. If your child is between 5 and 16 years old and attends a participating school, they may be able to join.
KathmanduAges 5–16 - NCT06720376Recruiting
Uveitis and arthritis study for Turkish patients
This study follows people with uveitis (eye inflammation) to learn more about how it relates to spondyloarthritis (arthritis of the spine). You may be able to join if you have uveitis, but not if you already had spondyloarthritis before your uveitis started or if your uveitis is caused by an infection.
Istanbul, MaltepeAges 18–75 - NCT06721104Recruiting
Balance and jaw health in autism
This study looks at balance, jaw joint function, and social skills in people with autism. It aims to understand how these areas are connected and could help improve care.
KirikkaleAges 4–21 - NCT06721299RecruitingPhase 1
Testing clenbuterol for muscle health in FSHD
This study tests a medication called clenbuterol to see if it can reduce activity of the DUX4 gene, which is believed to cause muscle damage in FSHD. If you have FSHD type 1 or 2, you may be able to join and help researchers understand if this drug can improve muscle health.
Kansas City, KansasAges 18–75 - NCT06723678Recruiting
Bone changes around implants with All-on-Four technique
This trial tests a special technique called 'All-on-Four' for people who need full-arch dental implants. It looks at how the bone around the implants changes over time. If you are in good general health and have a healthy jawbone, this study might help you understand if this approach works well for you.
Cairo, Nasr CityAges 50–65 - NCT06724029Recruiting
Neurosurgery outcomes research for multiple conditions
This study collects data from people having brain or spine surgery for many different conditions. It aims to understand how well different treatments work and how people recover. If you are scheduled for certain brain, spine, or nerve surgeries, you may be able to join.
Bergamo, BGAges 18 years+ - NCT06724224Recruiting
Comparing thyroid hormone drugs for babies with low thyroid
This study compares two types of levothyroxine (a thyroid hormone medicine) to see which works better for newborns and children with congenital hypothyroidism (a condition where the thyroid gland doesn't work properly from birth). If your child was diagnosed early and lives in the Emilia-Romagna region of Italy, this trial may help find the best treatment.
Bologna, BolognaAges Up to 11 years - NCT06725823Recruiting
Shoulder block comparison for frozen shoulder pain relief
This study tests two types of nerve blocks for frozen shoulder. It will see if one works better than the other to improve movement and reduce pain.
SohagAges 19–65 - NCT06726434Recruiting
Comparing freezing vs. surgery for foot spasticity after stroke
This trial compares a freezing procedure (cryoneurotomy) with standard surgery to treat foot stiffness after a stroke. It aims to see which method better corrects the foot turning inward and downward, helping you walk more easily.
GarchesAges 18 years+ - NCT06726629Recruiting
Italian Knee Questionnaire Study
This study is testing a new Italian version of a questionnaire that measures how your knee feels and works after knee replacement. The goal is to make sure the questionnaire is accurate for Italian-speaking patients.
BolognaAges 18–85 - NCT06728735Recruiting
Genetic study for congenital hypothyroidism with normal thyroid location
This study uses advanced genetic testing to find the cause of permanent congenital hypothyroidism in children who have a thyroid gland in the normal position. It may help families understand why their child developed this condition.
Bologna, BolognaAges Up to 18 years - NCT06728462Recruiting
Calcium supplement study for postmenopausal women with osteoporosis
This study tests a new form of calcium (amorphous calcium carbonate) to see if it can improve bone density in postmenopausal women with osteoporosis. It may offer an alternative for women who cannot or choose not to take other osteoporosis medications.
Kaohsiung CityAges 60–90 - NCT06728579RecruitingPhase 2
Group therapy for joint pain in breast cancer survivors
This study tests two supportive group programs—one using mindfulness skills, the other providing supportive talk therapy—to help breast cancer survivors manage joint pain caused by hormone-blocking pills. If you have ongoing joint pain and are taking an aromatase inhibitor, you may be able to join a free, video-based group.
San Diego, CaliforniaAges 18 years+ - NCT06730334Recruiting
Psoriatic arthritis study using ultrasound to track activity
This study uses power Doppler ultrasound to classify and measure how active your psoriatic arthritis is. It may help doctors better understand and treat your condition.
Nanjing, JiangsuAges 18 years+ - NCT06731608Recruiting
Fracture prevention study for older adults in rehab
This study tests a system to help prevent another broken bone after a hip, leg, or pelvis fracture. It is for people 65+ who are in a skilled nursing facility for rehab and plan to return home or to assisted living.
Baltimore, MarylandAges 65 years+ - NCT06731855Recruiting
Recovery study: blood markers in newborns after intestine surgery
This study looks at blood markers in newborns after major stomach or intestine surgery. It aims to understand recovery and could help improve care for babies with similar conditions.
Liverpool, MerseysideAges Up to 5 days - NCT06732674Recruiting
Home-based care for lung disease in rheumatic conditions
This trial tests whether people with lung disease caused by a rheumatic condition can safely manage their care at home using a smartphone or tablet. It aims to see if home monitoring is as effective as in-person visits for keeping your lungs healthy.
OsloAges 18 years+ - NCT06732895RecruitingPhase 2
Weekly injection for teens with achondroplasia
This trial tests a weekly injection called navepegritide for adolescents aged 12-18 with achondroplasia (a common form of dwarfism). The goal is to see if it can safely improve growth. You must have a genetic confirmation of achondroplasia and a historical height measurement from the past 6 to 15 months.
MontrealAges 12–17 - NCT06733025Recruiting
Comparing surgery and Botox for arm spasticity
This trial compares two treatments—Botox injections or surgery—for arm and hand spasticity after a stroke, brain injury, or spinal cord injury. It may help you decide which option works best for you.
MölndalAges 18 years+ - NCT06734689Recruiting
Genes and heart inflammation from immunotherapy
This study looks at genetic factors that may affect the risk of heart inflammation (myocarditis) caused by immune checkpoint inhibitors (ICIs), a type of cancer immunotherapy. It aims to find out if your genes make you more likely to develop this side effect.
ParisAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.