Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT06735027Recruiting
Steroid shot vs nerve block for shoulder arthritis
This trial compares two kinds of injections for shoulder pain caused by arthritis or rotator cuff problems. The goal is to see which one works better for pain relief.
Minneapolis, MinnesotaAges 18–99 - NCT06736457Recruiting
Safety and performance of AdvanCore bone void filler
This study tests a new bone filler called AdvanCore for people with a single bone fracture or defect that needs a graft. It aims to see if the filler is safe and works well to help the bone heal.
Guimarães, Braga DistrictAges 18 years+ - NCT06736756Recruiting
Stretching hip muscle to help with knee pain
This trial tests if stretching the tensor fascia lata muscle (near your hip) changes how the muscle on the inside of your kneecap works. It is for people who have front knee pain without a specific injury, especially when doing things like running, squatting, or climbing stairs.
CairoAges 18–30 - NCT06737289Recruiting
Surgical guide effectiveness study
This trial tests whether using surgical guides in dental implant surgery leads to better outcomes. It may help if you are between 18 and 80 and are planning to get dental implants.
MadridAges Any age - NCT06739369Recruiting
Arterial stiffness and arthritis features study
This study looks at how stiff your blood vessels (arteries) are and how that relates to arthritis symptoms in people with ankylosing spondylitis. It involves simple tests to measure blood vessel health along with your regular arthritis care.
KırşehirAges 18–85 - NCT06740162Recruiting
Physical activity program for adults with intellectual disabilities
This study tests a program to help adults with intellectual disabilities become more physically active. You and your caregiver will work with a coach to increase your daily movement, with the goal of improving health and community connection.
Fayetteville, ArkansasAges 18 years+ - NCT06744036Recruiting
Exercise and electrical stimulation for knee arthritis
This study tests whether adding a gentle electrical current (interferential therapy) to a personalized exercise program can reduce pain and improve function in people with knee osteoarthritis. If you have knee pain from arthritis and have not had physical therapy or certain injections in the past six months, you may be able to join.
São PauloAges 40–75 - NCT06744257Recruiting
Online education for kneecap pain while waiting for physio
This trial tests whether an online education program is helpful for people with kneecap pain who are waiting for in-person physiotherapy. It aims to see if this approach is practical and beneficial.
ColchesterAges 16–44 - NCT06745544Recruiting
Exercise program to prevent falls in older adults with diabetes
This trial tests whether a special exercise program (with music and multitasking) can help reduce falls and fractures and improve heart health in older adults with diabetes. If you are 65+ and have diabetes, you may be able to join and get free exercise classes.
Aalborg, NorhAges 65 years+ - NCT06745791Recruiting
Testing a new spine MRI technique (BoneMRI)
This study is testing a new MRI technique called BoneMRI that may show bones more clearly than standard MRI. If you already need both a CT and an MRI of your spine, your scans could be used to compare this new method with the regular ones.
GhentAges 12 years+ - NCT06746922Recruiting
Brain stimulation for fibromyalgia pain
This study tests a type of non-invasive brain stimulation called Intermittent Theta Burst Stimulation (iTBS) to see if it can help reduce pain and improve daily function in people with fibromyalgia. It may offer a new option for managing your pain without medication changes.
Izmir, KarabaglarAges 18–65 - NCT06747039Recruiting
Cannabis extract for fibromyalgia pain
This trial tests a cannabis extract called Avextra 10/10 for people with fibromyalgia who haven't gotten better with standard treatments. It aims to see if this option can help manage pain and other symptoms.
Milan, MilanoAges 18 years+ - NCT06747052Recruiting
How gender affects physical activity for preventing joint pain
This study looks at how being male or female affects physical activity habits and how that might help prevent long-term muscle and joint problems. It is open to adults in Lombardy, Italy, who can speak Italian.
Milan, ItalyAges 18–64 - NCT06747494Recruiting
Comparing general vs spinal anesthesia for hip or knee replacement
This study compares two types of anesthesia (general and spinal) for people having a total hip or knee replacement. The goal is to see which approach is better for recovery and overall outcomes.
Miami, FloridaAges 18 years+ - NCT06747949RecruitingPhase 3
Long term extension study of dazodalibep for Sjogren's syndrome
This study gives continued access to the study drug dazodalibep for people with Sjogren's syndrome who completed a prior phase 3 study. The goal is to see how safe and effective the medication is over a longer period.
Avondale, ArizonaAges 18 years+ - NCT06748651RecruitingPhase 1
Allocetra injection for jaw joint arthritis
This study tests a new injection called Allocetra directly into the jaw joint to treat pain and inflammation in temporomandibular joint osteoarthritis. Eligible participants must have MRI-confirmed inflammation and meet basic health requirements.
Ramat GanAges 18–60 - NCT06748976Recruiting
Brain activity study during attention tasks
This study looks at how your brain controls attention by measuring brain activity while you perform tasks. It may help researchers understand attention better.
Oro Verde, Entre Ríos ProvinceAges 18–60 - NCT06749366Recruiting
Finding Genes Linked to Cartilage Tumors and Blood Vessel Issues
This study uses genetic testing to find genes that cause certain types of cartilage tumors and blood vessel problems. If you or your child has one of these conditions, joining could help doctors understand what causes them and find better treatments.
Bethesda, MarylandAges 2–100 - NCT06750055Recruiting
Walking assessment after lumbar spinal stenosis surgery
This study looks at how well people walk after surgery for lumbar spinal stenosis. It may help you understand your recovery if you had surgery 6 weeks to 3 months ago.
DenizliAges 20–65 - NCT06753019Recruiting
Knee Osteoarthritis: Thoughts, Feelings, and Function
This study looks at how your thoughts and feelings about knee pain (and your daily function) relate to osteoarthritis. It aims to help understand your overall health better.
IspartaAges 40–84 - NCT06753565RecruitingPhase 2
L-carnitine supplement for rheumatoid arthritis
This trial tests whether adding L-carnitine (a natural substance) to your current treatment helps reduce rheumatoid arthritis symptoms. It could be an option if your arthritis is still active despite taking standard medications.
Cairo, DemerdashAges 18–60 - NCT06754098RecruitingPhase 2
Testing two drugs for TK2 deficiency
This trial tests two experimental drugs, Doxecitin and Doxribthymine, for adults with a rare genetic condition called TK2 deficiency that causes muscle weakness and breathing problems. The goal is to see if these drugs can slow or stop the disease.
MadridAges 18 years+ - NCT06754982Recruiting
Timing of pain, stiffness, and function in plantar fasciitis after muscle release
This trial tests whether a hands-on therapy called myofascial release can help with morning pain, stiffness, and walking in people with plantar fasciitis. It aims to see how these symptoms change over time after treatment.
Talca, Maule RegionAges 18–60 - NCT06755138Recruiting
Scoliosis, pain, and quality of life in Duchenne muscular dystrophy
This study looks at how scoliosis (curved spine) and back pain affect daily life in people with Duchenne muscular dystrophy. Researchers will measure muscle strength and compensation patterns to understand these links.
SeoulAges 11–30
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.