Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT07048418Recruiting
Nose job results in adults born with a cleft lip and palate
This trial asks adults who had a nose job as teens or children, after being born with a cleft lip and palate, to rate how they look and feel about their nose. Their answers will help doctors understand how these surgeries affect patients long-term.
MontpellierAges 18–30 - NCT07052565Recruiting
CAR-T cell therapy for autoimmune diseases
This trial uses your own engineered immune cells (CAR-T cells) to treat severe autoimmune diseases like rheumatoid arthritis, lupus, Sjögren's syndrome, or systemic sclerosis that haven't improved with standard medicines. The goal is to see if this treatment can calm the immune system and reduce disease activity.
HefeiAges 18 years+ - NCT07054333Recruiting
Pain regulation after online therapy for fibromyalgia
This study looks at how pain processing changes after internet-based cognitive behavioral therapy (CBT) for fibromyalgia. You will come to Karolinska Institutet for pain tests 3 to 4 times to help researchers understand if the therapy affects how your body handles pain.
Stockholm, Stockholm CountyAges 18 years+ - NCT07055113Recruiting
Home rehab program for hip or knee arthritis
This study tests a home-based rehab program for people with hip or knee arthritis who do not need joint replacement yet. It aims to help improve function and reduce pain through online sessions.
Edmonton, AlbertaAges Any age - NCT07056881Recruiting
Single vs Combination Antibiotics for Pseudomonas Bone Infections
This trial compares using one antibiotic alone versus a combination of two antibiotics to treat bone infections caused by Pseudomonas aeruginosa. The goal is to see which approach works better for treating the infection.
Saint-Denis, FranceAges 18 years+ - NCT07057063Recruiting
Light therapy for knee pain and swelling
This study tests if light therapy can reduce knee pain and swelling (synovitis) caused by arthritis. If you have long-lasting knee pain and arthritis, this treatment might offer a non-drug option to help you feel better.
ShenzhenAges 40–80 - NCT07058623Recruiting
Nurse-led telehealth vs in-person follow-up after knee replacement
This trial compares follow-up care with a nurse via video calls or phone versus in-person visits after your first total knee replacement. It aims to see if telehealth is as good as in-person for your recovery.
Hong KongAges 18 years+ - NCT07058636Recruiting
Nerve block plus trigger point shots for neck pain relief
This study tests if adding a nerve block to standard trigger point injections provides better relief for people with chronic neck pain caused by myofascial pain syndrome.
AnkaraAges 18–65 - NCT07059663Recruiting
Schroth method with core exercises for scoliosis
This study tests if adding core-strengthening exercises to the Schroth method helps teenagers with idiopathic scoliosis better than the Schroth method alone. It aims to find a more effective way to improve posture and reduce curve progression.
Lahore, Punjab ProvinceAges 10–18 - NCT07060430Recruiting
Comparing two wrist therapies after Colle's fracture
This study compares two types of gentle hand exercises to help people whose wrists have become stiff after a Colle's fracture. The goal is to see which approach works better for restoring wrist movement.
IslamabadAges 40–70 - NCT07062523RecruitingPhase 1/Phase 2
FAPI PET scan for Sjögren's syndrome inflammation
This study uses a special PET scan (FAPI PET) to look at inflammation in people with Sjögren's syndrome. It helps doctors understand how active the disease is. You may join if you have Sjögren's syndrome or a solid tumor that needs this scan, and you are not on certain medications.
BeijingAges 18–80 - NCT07065487Recruiting
Comparing two digital scanning methods for full-arch implant teeth
This trial tests two different ways of taking digital scans of the mouth to make a full set of teeth supported by four implants in the lower jaw. It compares a standard scanning method with a new pattern-assisted technique to see which is more accurate.
Al Mansurah, Dakahlia GovernorateAges 30–70 - NCT07065747Recruiting
Understanding inflammation in uveitis using advanced eye imaging
This study uses a special eye scan (OCT) to measure and classify inflammatory cells inside the eye. It aims to better understand different types of uveitis and improve diagnosis and treatment.
Portland, OregonAges 5–85 - NCT07066228Recruiting
Rebuilding bone using a patient's own stem cells
This trial tests whether using a patient's own bone marrow stem cells can help repair large gaps in the shin or arm bones that haven't healed on their own. The stem cells are grown in a lab to create new bone tissue, which may avoid the need for metal implants or donated bone.
Xinxiang, HenanAges 18–55 - NCT07067827Recruiting
Osteoporosis survey for clinic patients
This trial tests a self-questionnaire for people with osteoporosis who are already being followed at certain clinics. It aims to see if the questionnaire helps manage the condition.
Québec, QuebecAges 18 years+ - NCT07069179Recruiting
Choose to Move replacement study for older adults
This study tests a program called Choose to Move Replacement Ready (CTM-RR) designed for older adults. It looks at how well activity coaches and healthcare referral partners can help people get active.
Vancouver, British ColumbiaAges 50 years+ - NCT07069426Recruiting
Protein and muscle loss during leg immobilization
This study tests how different amounts of dietary protein affect your muscles when your leg is temporarily immobilized in a brace. If you are a healthy, active adult, you might help researchers learn how to prevent muscle loss during periods of reduced activity.
Natick, MassachusettsAges 17–39 - NCT07072091Recruiting
Whole-body vs shoulder physiotherapy for volleyball players
This trial compares two physiotherapy approaches for volleyball players: one focusing only on the shoulder, and another looking at the whole body. It aims to find which method helps prevent or reduce shoulder problems.
Trieste, TriesteAges 17–30 - NCT07077304Recruiting
Cardiac imaging study for inflammatory heart diseases
This study uses heart scans (MRI or nuclear imaging) to better understand inflammatory heart conditions. If you have a suspected inflammatory heart disease and are already scheduled for one of these scans, you may be able to join.
ParisAges 18 years+ - NCT07078877Recruiting
Laser therapy for knee osteoarthritis: a new option?
This study tests whether low-level laser therapy (a painless, non-surgical treatment using light) can reduce knee pain and improve knee function, cartilage health, and muscle strength in people with moderate knee osteoarthritis. It may be an option if you haven't had recent knee injections or physical therapy.
Ankara, YENIMAHALLEAges 50 years+ - NCT07079254Recruiting
Meniscus repair vs. partial removal for bucket-handle tears
This trial compares two surgeries for a specific type of meniscus tear that blocks knee straightening: repairing the torn meniscus versus removing the damaged part. The goal is to see which leads to better recovery.
Hässleholm, Skåne CountyAges 15 years+ - NCT07080710Recruiting
Same-day dental implants for front teeth
This trial tests placing a dental implant right after removing a failing front tooth. It aims to see if this immediate approach works well in the upper jaw area between the canine teeth.
Ghent, East FlandersAges 20 years+ - NCT07080814Recruiting
Balance exercises after knee replacement
This study tests whether special balance exercises on a platform can help people who have recently had a knee replacement walk better and feel steadier.
Ankara, YenimahalleAges 18 years+ - NCT07081620Recruiting
Freezing rib nerves before chest-wall repair
This study tests how the timing of a nerve-freezing procedure (cryoneurolysis) in the ribs affects recovery from pectus excavatum surgery. It may help reduce pain after the operation.
Bergamo, BGAges 12–40
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.