Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT07026305Recruiting
Comparing surgical approaches for lumbar spinal stenosis
This study is comparing two surgical approaches for patients with lumbar spinal stenosis (narrowing of the lower spine). It aims to see if a less invasive surgery works as well as a more extensive procedure, which may help patients recover faster.
MadridAges 50 years+ - NCT07026552Recruiting
Ligament study for lumbar spinal stenosis
This study looks at the ligament in your lower back to understand how lumbar spinal stenosis develops. It involves analyzing tissue samples and may help find better ways to treat this condition.
Rome, RMAges 50–85 - NCT07027306Recruiting
New score to guide treatment for osteoporotic spine fractures
This study tests a new classification system to help doctors decide the best treatment for spine fractures caused by osteoporosis. It aims to improve pain and mobility by matching treatment to fracture type.
San Francisco, CaliforniaAges 50 years+ - NCT07030205Recruiting
Brain imaging study for women with osteoporosis
This study uses brain scans (MRI) to look at how the brain might be linked to bone health in women with osteoporosis. It compares women with osteoporosis to healthy women of the same age.
Clermont-FerrandAges 50 years+ - NCT07034196Recruiting
Comparing RA care: primary care vs. rheumatologist
This study compares RA care from your primary care doctor (with extra training) to care from a rheumatologist. It's for people with stable RA living in northern New York who want to see if primary care can work as well as a specialist.
Potsdam, New YorkAges 18 years+ - NCT07036445Recruiting
PRP vs steroids for leg pain from a slipped disc
This study compares two treatments—platelet-rich plasma (PRP) and steroids—given as an injection into the spine for leg pain caused by a herniated disc. It's for people who haven't improved after 6 weeks of standard care.
MérignacAges 18 years+ - NCT07037251Recruiting
Screening for fibromyalgia in suspected endometriosis
This study screens women with suspected endometriosis for fibromyalgia during their first visit to the clinic. It aims to find out if the two conditions often occur together so they can be treated together.
AshdodAges Any age - NCT07037472Recruiting
Imaging calcium deposits in dermatomyositis patients
This study uses a special imaging technique (photoacoustic/ultrasound) to look at calcium deposits under the skin in people with dermatomyositis. It aims to find patterns that help doctors understand the condition and track how well treatments work.
BeijingAges 18–80 - NCT07037862RecruitingPhase 1/Phase 2
Study of ENTR-601-44 for Duchenne muscular dystrophy (exon 44 skipping)
This trial tests a new medicine called ENTR-601-44 for people with Duchenne muscular dystrophy whose genetic mutation can be treated by skipping a part of the gene called exon 44. The goal is to see if it is safe and helps with muscle function.
GhentAges 4–20 - NCT07038200RecruitingPhase 3
Study of Del-brax (AOC 1020) for People with FSHD
This study tests an experimental medicine called Del-brax (AOC 1020) for people with facioscapulohumeral muscular dystrophy (FSHD). The goal is to see if it can help improve muscle strength and slow the disease. You may be able to join if you have a confirmed FSHD diagnosis and can walk at least 10 meters on your own.
Orange, CaliforniaAges 16–70 - NCT07038824RecruitingPhase 1/Phase 2
A study of ENTR-601-45 for Duchenne MD (exon 45 skipping)
This trial tests an experimental drug called ENTR-601-45 for people with Duchenne muscular dystrophy that can be treated with 'exon 45 skipping.' The goal is to see if it's safe and helps improve muscle function. It's for males between 4 and 20 who can still walk and have enough arm strength.
GhentAges 4–20 - NCT07039799Recruiting
Virtual reality for arm function in Duchenne
This trial tests whether using virtual reality (VR) games can help improve arm and hand function in people with Duchenne muscular dystrophy. It may be a fun and engaging way to do exercises that strengthen your upper body.
Istanbul, FatihAges 7–18 - NCT07039968RecruitingPhase 2
Standard vs. high dose radiation for spine cancer spread
This trial compares standard and higher doses of focused radiation (stereotactic radiosurgery) to treat cancer that has spread to the spine. It aims to find if a higher dose works better while keeping side effects manageable.
TaipeiAges 18 years+ - NCT07040878Recruiting
Antigravity treadmill after hip or knee replacement
This study tests whether walking on a special antigravity treadmill (which reduces weight on your joints) helps people recover faster after hip or knee replacement surgery. It's designed for people who are 60 or older and can walk on their own.
Trzebnica, Lower Silesian VoivodeshipAges 60–75 - NCT07040930RecruitingPhase 1
Testing the safety of GenSci120 in healthy adults
This study tests a new drug called GenSci120, given as multiple injections under the skin, to see if it is safe in healthy adults. It will also measure how the drug moves through the body and how it affects certain immune markers.
Shanghai, Shanghai MunicipalityAges 18–55 - NCT07043166Recruiting
Heart, kidney, and metabolic health study in Shanghai
This study looks at the link between heart, kidney, and metabolic health in adults living in Shanghai. It follows people who were part of an earlier health study to see how their health changes over time.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07043335Recruiting
Mesotherapy vs. shock wave for tennis elbow pain
This trial compares two treatments for tennis elbow: mesotherapy (injections into the skin) and shock wave therapy (sound waves). It aims to find which works better for pain that has lasted at least 6 weeks.
IstanbulAges 18–65 - NCT07044206Recruiting
Comparing two bone graft materials for lumbar fusion surgery
This trial compares two types of bone graft materials (Magnetos Putty and GlassBone Putty) used in lower back fusion surgery for adults with degenerative disc disease. The goal is to see which material works better for helping the bones fuse together, which may reduce pain and improve function.
Montpellier, FranceAges 18–80 - NCT07045519Recruiting
Vibration therapy for walking and balance in cerebral palsy
This study tests whether a gentle vibrating device applied to the legs can improve walking and balance in children with cerebral palsy. It may help reduce muscle tightness and make moving easier.
AnkaraAges 4–18 - NCT07045714Recruiting
Endoscopic back surgery for spinal stenosis
This study looks at a newer, less invasive type of back surgery called endoscopic laminotomy. It may help people with lumbar spinal stenosis (narrowing of the spinal canal) who still have leg or back pain after trying physical therapy and pain medicines for at least 3 months.
San Pedro Garza García, Nuevo LeónAges 18–74 - NCT07045896Recruiting
Fucoidan for active rheumatoid arthritis
This trial tests a seaweed extract called fucoidan to see if it can help people with active rheumatoid arthritis that is not well controlled by their current treatments. If you have moderate-to-high disease activity despite therapy, you may be able to join.
BeijingAges 18–65 - NCT07047703RecruitingPhase 1/Phase 2
A study of an experimental drug for axial spondyloarthritis
This trial tests an investigational drug for people with axial spondyloarthritis (a type of inflammatory arthritis affecting the spine and pelvis). It also includes a group of healthy volunteers for comparison. The study aims to see if the drug is safe and effective.
BirtinyaAges 18–65 - NCT07047846Recruiting
Bowen technique vs. soft tissue therapy for frozen shoulder pain
This study compares two massage-like treatments (Bowen technique and dynamic soft tissue mobilization) to see which better reduces pain, improves movement, and helps daily function in people with frozen shoulder. It only includes diabetic patients with specific stages of frozen shoulder.
Lahore, Punjab ProvinceAges 50–80 - NCT07048366Recruiting
Mindfulness in a museum for fibromyalgia pain relief
This study tests whether a mindfulness program held in a museum setting can help women with fibromyalgia feel less pain and improve their quality of life. You would attend sessions in a museum and practice mindfulness techniques.
Chieti, AbruzzoAges 18–60
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.