Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT07122323Enrolling by invitation
Robot-assisted hip replacement for Legg-Calve-Perthes disease
This trial compares robot-assisted total hip replacement to the usual surgery for people with Legg-Calve-Perthes disease. It aims to see if the robotic arm helps the surgery go more smoothly.
Hangzhou, ZhejiangAges 18–80 - NCT07120854Enrolling by invitation
Decision aid for osteoporosis treatment in postmenopausal women
This study tests a decision-making tool to help postmenopausal women choose whether to take medication to prevent bone fractures. It's for women who have not had a fracture but have an elevated fracture risk.
BarcelonaAges 50 years+ - NCT07095374Enrolling by invitation
How jaw widening affects premolar tilt
This study looks at how widening the upper jaw with a special device (rapid palatal expander) affects the tilt of certain teeth (premolars). It may help doctors understand how to plan better orthodontic treatments.
Pavia, LombardyAges 6–14 - NCT07093229Enrolling by invitation
Gait analysis for knee arthritis in seniors
This trial studies how walking patterns change in people over 65 with long-term knee osteoarthritis. It aims to understand gait to improve treatment and rehabilitation plans.
CraiovaAges 65–80 - NCT07090772Enrolling by invitation
Comparing jaw position methods for splint therapy in TMJ disc displacement
This trial tests different ways to determine the best jaw position for a mouth splint used to treat a specific type of temporomandibular joint (TMJ) problem where the disc is out of place and doesn't go back. The goal is to see which method works better for reducing pain and improving jaw function.
Fuzhou, FujianAges 13–50 - NCT07090694Enrolling by invitationPhase 1
Sinus lift with or without platelet-rich fibrin for dental implants
This trial compares two ways to place dental implants in the upper jaw where there is not enough bone: one uses a special clotting substance (PRF) and the other does not. The goal is to see which method works better.
RiyadhAges 25–65 - NCT07072676Enrolling by invitation
Can a walker help prevent falls in neuromuscular disease?
This study tests if using assistive walking devices, after a short training period, can lower the risk of falls in people with neuromuscular diseases. It aims to help you stay steady and safe on your feet.
Bad FeilnbachAges 65–65 - NCT07070245Enrolling by invitation
Comparing two therapies for plantar fasciitis pain
This study compares two hands-on treatments for plantar fasciitis: a technique using tools to massage the tissue and a method that involves holding the foot in a specific position. It aims to see which better reduces heel pain and improves movement.
Port Said, Port Said GovernorateAges 30–50 - NCT07066852Enrolling by invitation
Hip screening for Turkish newborns at risk
This trial checks how well a hip screening program works for Turkish babies born in a specific hospital. It aims to find developmental hip problems early so they can be treated.
Ankara, AnkaraAges Any age - NCT07062757Enrolling by invitation
Massage and melatonin for jaw surgery recovery
This study tests whether combining gentle lymphatic drainage massage with melatonin can reduce pain and swelling after jaw surgery. If you are scheduled for jaw surgery for the first time and are otherwise healthy, you may be able to join.
Istanbul, FatihAges 16–55 - NCT07060235Enrolling by invitation
Mobile app for disc herniation recovery
This trial tests a mobile app that guides you through exercises for disc herniation. The app is designed to help strengthen the muscles that support your spine and may reduce pain.
AnkaraAges 20–55 - NCT07056322Enrolling by invitation
Optimal meals to reduce bone loss in women with thinning bones
This trial tests whether specific meals can lower bone breakdown in postmenopausal women with osteopenia (thinning bones). It may help prevent osteoporosis by identifying a meal plan that protects bone health.
Aarhus NAges Up to 80 years - NCT07055971Enrolling by invitation
Pain education and brain training for fibromyalgia
This trial tests whether a program that teaches you about pain and helps your brain control pain better can improve fibromyalgia symptoms. It also looks at how emotions play a role.
Granada, AndalusiaAges 18 years+ - NCT07054450Enrolling by invitation
Assessment and rehabilitation for chronic pinched nerve in the neck
This trial tests a program of assessment and rehabilitation (including physical exercise and possibly a nutraceutical supplement) for people with chronic cervical radiculopathy — a pinched nerve in the neck causing pain, numbness, or weakness in the arm. It may help reduce pain and improve function without surgery.
CraiovaAges 50–79 - NCT07053566Enrolling by invitation
Back muscle strengthening for rotator cuff tendinopathy
This study tests whether strengthening a back muscle (latissimus dorsi) helps people with rotator cuff tendinopathy. You may be able to join if you have had shoulder pain for at least 3 months and meet certain medical criteria.
AnkaraAges 18–50 - NCT07038447Enrolling by invitationPhase 1
KITE-363 for refractory autoimmune diseases
This trial tests a new cell therapy called KITE-363 for people with certain autoimmune diseases (lupus, lupus nephritis, systemic sclerosis, or idiopathic inflammatory myopathy) that haven't improved with standard treatments. It aims to see if this therapy can help control the disease.
Duarte, CaliforniaAges 18 years+ - NCT07017101Enrolling by invitation
Exercise for better breathing, less fatigue in fibromyalgia
This trial combines Pilates with special breathing techniques to see if it helps people with fibromyalgia breathe easier, feel less tired, and have a better quality of life. It compares this combined approach to Pilates alone.
Istanbul, TuzlaAges 18–65 - NCT07011537Enrolling by invitation
Digital health program and TENS for chronic low back pain
This trial tests a digital health program combined with a TENS device (a small device that sends gentle electrical pulses to help with pain) for people with ongoing low back pain. It compares this approach to standard care, and you would be randomly assigned to one of the two groups.
Eden Prairie, MinnesotaAges 18 years+ - NCT07011303Enrolling by invitation
Using your own blood clot to help bone heal after tooth extraction
This study tests whether placing a special clot made from your own blood (called Platelet Rich Fibrin) into the socket after a tooth extraction helps the bone heal better for a future dental implant.
Tokat ProvinceAges 18–40 - NCT07006389Enrolling by invitation
Shock wave therapy for plantar fasciitis follow-up study
This study looks at how well shock wave therapy works for people with plantar fasciitis that hasn't improved with other treatments. If you've already had shock wave therapy 3 to 6 months ago, your experience could help doctors understand what makes the treatment effective.
IstanbulAges 18 years+ - NCT07003802Enrolling by invitation
Understanding back muscle control in disc injury
This study looks at how the brain controls back muscles in people with chronic disc injuries. It compares patients before surgery or physical therapy to healthy controls to better understand muscle function.
La Jolla, CaliforniaAges 18–60 - NCT07001969Enrolling by invitation
Percutaneous facet spine fixation for instability
This study tests a minimally invasive procedure to fix unstable vertebrae in the neck or lower back using a small incision. It may help people with spinal instability causing nerve symptoms or pressure on the spinal cord.
Cairo, ShoroukAges Any age - NCT06988163Enrolling by invitation
Osteoarthritis care tools for primary care doctors
This study tests a tool to help doctors manage osteoarthritis care. You may join if you are a healthcare provider at the UNC pilot clinic or a patient who has been referred to the 'Walk With Ease' program by that clinic, are 18 or older, and speak English.
Chapel Hill, North CarolinaAges 18–99 - NCT06982456Enrolling by invitation
Manual therapy for neck pain in physiotherapy students
This study tests if manual therapy techniques help students with localized neck pain feel better. It focuses on pain in the upper shoulder muscle.
MurciaAges 18–40
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.