Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,845 recruiting studies in this area right now.
By phase
- Not applicable3,977
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3148
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis73
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida82
- Massachusetts77
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,845 total
- NCT04251429Enrolling by invitation
Healthy workplace program for public healthcare workers
This trial studies a workplace program delivered by trained peers to improve health in public-sector healthcare facilities. You may be able to join if you are a direct employee of the agency that runs the facility.
Ages 18 years+ - NCT04240821Enrolling by invitationPhase 2
Theophylline for pseudohypoparathyroidism after prior study
This Phase 2 trial tests whether the medicine theophylline can help people with pseudohypoparathyroidism. You may be eligible only if you already completed a specific earlier randomized Phase 2 study.
Nashville, TennesseeAges 2–99 - NCT04204135Enrolling by invitation
Tracking hip flexor weakness after specific spine surgeries
This trial follows how hip flexor strength changes after two types of lower-back surgeries (ALIF or LLIF). It may help doctors better predict and prevent weakness in the hip and leg after surgery.
Chicago, IllinoisAges Up to 65 years - NCT04190758Enrolling by invitation
Early arthritis study for RA, psoriatic arthritis, and psoriasis
This study looks at people with early arthritis related to rheumatoid arthritis, psoriatic arthritis, or psoriasis. Researchers want to understand how these early conditions behave and may help guide better treatment decisions.
GothenburgAges 18–80 - NCT04147559Enrolling by invitation
Long-term follow-up for a specific hip replacement stem
This study checks how well a particular hip replacement stem (the PROFEMUR Preserve Classic Femoral Stem) and matching parts keep working over many years. You may be invited if you had that exact hip replacement combination and can return for long-term checkups.
Scottsdale, ArizonaAges 21 years+ - NCT04145401Enrolling by invitation
Long-term follow-up for a specific knee revision implant
This study tracks how well a particular knee revision implant performs over many years. It may help you by closely monitoring your knee after revision surgery and adding to long-term safety and performance data.
Englewood, ColoradoAges 21 years+ - NCT04064008Enrolling by invitation
Long-term follow-up for a specific hip revision stem
This study follows people who had a hip replacement redone (revision) because of bone healing problems or hardware removal, using a specific revision femoral stem. It checks how the stem does over time and follows up for up to 10 years after surgery.
OtwockAges Any age - NCT04003311Enrolling by invitation
Follow-up for specific shoulder implant types and surgery
This study checks outcomes in people who already received certain Zimmer Biomet shoulder implant components using the correct surgical technique. It may help improve how these specific implants are used and monitored after surgery.
Boise, IdahoAges 18 years+ - NCT04003272Enrolling by invitation
Reverse shoulder implant study for severely damaged rotator cuff
This trial studies a specialized reverse shoulder implant system for people whose rotator cuff is badly damaged or who had a prior shoulder replacement that failed. It aims to reduce pain and improve function by improving how your shoulder works, especially when the rotator cuff can’t do its job.
Louisville, KentuckyAges 18 years+ - NCT03836300Enrolling by invitation
Parent-infant coaching for families with young diagnoses
This study tests a parent-and-infant coaching program for babies and caregivers. It aims to see whether the program helps after an early diagnosis when English is used at home.
Research Triangle Park, North CarolinaAges Up to 99 years - NCT03755245Enrolling by invitation
Imaging study using a tracer to measure inflammation in joints and lungs
This trial tests how a radioactive imaging medicine (a tracer called 68Ga-DOTA-Siglec-9) spreads in the body and how well it shows inflammation. It includes both healthy volunteers and people with active rheumatoid arthritis, vasculitis, or pulmonary sarcoidosis to see if the scan matches disease activity.
TurkuAges 18–70 - NCT03681977Enrolling by invitation
Compare two knee replacement systems for osteoarthritis outcomes
This study compares results from two specific knee replacement systems for people with knee osteoarthritis. It may help find which device works better for pain and function after knee replacement surgery.
Montreal, PQAges 18–80 - NCT03649490Enrolling by invitation
Testing new spinal implant materials for XLIF fusion
This study compares different advanced materials used in a specific spinal fusion surgery (XLIF). It aims to see which implant material helps the bone fuse well and safely over time.
Hartford, ConnecticutAges 18–80 - NCT03576573Enrolling by invitation
Follow-up study for specific hip replacement components
This study checks outcomes after a specific type of hip surgery using specific brand parts. You may help by sharing follow-up visit information so the sponsor can confirm the components work as expected in everyday patients.
BuxtehudeAges 21 years+ - NCT03501589Enrolling by invitation
Medicine aims to help regrowing growth cartilage
This trial is testing a treatment intended to affect the growth plate—the cartilage area that helps bones grow—in people who still are growing. It looks at whether changing signals in the growth plate can improve healing or regrowth after surgery removes part of that area as part of routine care.
Rochester, MinnesotaAges Any age - NCT03484325Enrolling by invitation
Patient registry for joint replacement and related surgeries
This trial is a “registry,” meaning it collects information from people who choose certain elective joint surgeries. It may help doctors better understand outcomes and safety after procedures like hip and knee operations.
Houston, TexasAges 18–100 - NCT03429426Enrolling by invitation
Tracking joint bone damage in rheumatoid arthritis with scans
This study uses high-resolution scans and regular X-rays to see how bone erosions (bone wear) progress in people with rheumatoid arthritis over time. It may help researchers better understand disease changes and how to measure them.
AarhusAges 18 years+ - NCT03384927Enrolling by invitation
Dairy intake study for muscle stiffness in spasticity
This trial looks at whether eating dairy can reduce spasticity, or muscle stiffness/tightness. It’s testing dairy as an add-on by comparing your muscle symptoms and treatment goals during the study.
Glostrup MunicipalityAges Any age - NCT03244020Enrolling by invitationPhase 4
Aspirin or low-dose blood thinner after bone or leg surgery
This trial compares aspirin versus a low-dose injectable blood thinner (LMWH) to prevent blood clots after certain orthopedic cancer surgeries. It may help lower the risk of dangerous clotting while balancing bleeding and side effects.
Los Angeles, CaliforniaAges 18 years+ - NCT03178799Enrolling by invitation
Fracture care program to prevent future bone fractures
This trial tests a structured “fracture liaison service” program to help people after a new hip or spine (vertebral) fracture avoid additional fractures. It aims to improve long-term follow-up care over the next 10 years.
TaipeiAges 50–100 - NCT03011398Enrolling by invitation
Registry for Regenexx orthobiologics procedures in musculoskeletal care
This is a registry study that collects information from people who get a Regenexx procedure for certain musculoskeletal problems. It may help researchers better understand how these procedures are used and what outcomes people experience.
Phoenix, ArizonaAges Any age
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,845 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 8,007 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.