Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,771
- Phase 2215
- Phase 4199
- Phase 1182
- Phase 3139
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis171
- Rheumatoid Arthritis131
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University66
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas66
- Alabama60
- Illinois51
- Pennsylvania48
Recruiting studies4,610 total
- NCT07336849Recruiting
Embolization for chronic shoulder pain not helped by other treatments
This trial tests a minimally invasive procedure called transcatheter arterial embolization using tiny particles (Nexsphere-F) to reduce chronic shoulder pain that has not improved with physical therapy, medications, or injections. It aims to see if this treatment can safely improve pain and shoulder movement.
SeoulAges 19–85 - NCT07339605Recruiting
Gum bone regeneration with hyaluronic acid vs enamel matrix
This trial compares two treatments to help regrow bone and gum tissue around teeth with deep bone defects. It tests if hyaluronic acid works as well as enamel matrix derivative, both applied during a minimally invasive procedure.
Valencia, ValenciaAges 18 years+ - NCT07336303Recruiting
Ear acupuncture for thumb surgery pain
This study tests whether ear acupuncture (auriculotherapy) helps reduce pain after thumb arthritis surgery. If you're having this surgery and haven't tried ear acupuncture before, you may be able to join.
ParisAges 18 years+ - NCT07339475Recruiting
Using vein size to predict blood pressure drops in older adults during hip or leg surgery
This study uses an ultrasound to measure the size of a vein in your leg before surgery to see if it can predict a drop in blood pressure during the procedure. If you are over 60 and having planned lower-limb surgery with spinal anesthesia, this non-invasive test might help your doctors prepare for your care.
CairoAges 60 years+ - NCT07337824Recruiting
Two Neck Training Methods for Forward Head Posture
This study compares two types of training for university students with forward head posture: strengthening deep neck flexors (muscles at the front of the neck) and motor learning based on brain plasticity (teaching your brain new ways to control posture). The goal is to see which approach works better for improving head alignment.
Islamabad, CapitalAges 19–25 - NCT07342959Recruiting
Anchor surgery for elbow fracture in children
This trial studies a surgery using anchors to fix a broken bone in the elbow (the medial epicondyle) in children under 15. It aims to see how well this technique works for displaced fractures.
StrasbourgAges 1–14 - NCT07338760Recruiting
Core stability exercises effect on balance in archers
This study looks at whether doing core (trunk) muscle exercises for a short time can help archers with their balance and how well they can use their upper body when shooting. It is for archers who are already in a licensed program.
Kağıthane, IstanbulAges Any age - NCT07336394Recruiting
Study on rare heart muscle diseases using advanced MRI
This study uses a special heart MRI to better diagnose and understand rare heart muscle diseases. It may help doctors predict risks and make more accurate treatment decisions.
BeijingAges Any age - NCT07340242Recruiting
3D-Printed Braces vs. MARA for jaw alignment
This trial compares two types of braces (a 3D-printed removable brace and a fixed brace called MARA) to see which works better for correcting a bite problem where the lower jaw is too far back. It is designed for teenagers who are still growing and have a large overbite.
Al Mansurah, Dakahlia GovernorateAges 9–14 - NCT07336160Recruiting
Nutrition before knee replacement surgery
This trial studies a special nutrition plan before knee replacement surgery to see if it helps recovery. Participants follow enhanced recovery guidelines for eating and drinking before their operation.
Istanbul, IstanbulAges 18 years+ - NCT07338877Enrolling by invitation
Stem cell therapy for disc-related low back pain
This trial tests a new treatment that uses your own stem cells to help heal damaged discs in your lower back. The stem cells are injected into the disc during a minimally invasive procedure to reduce pain and improve function.
Košice, Košice RegionAges 18 years+ - NCT07342647Recruiting
Safer antibiotics for people with beta-lactam allergies in joint replacement surgery
This trial tests a better way to choose antibiotics during joint replacement surgery for patients who are allergic to beta-lactams (a common class of antibiotics). The goal is to prevent infections while avoiding allergic reactions.
StrasbourgAges 18 years+ - NCT07335718Recruiting
Radiofrequency therapy for low back pain from disc herniation
This trial tests if a type of radiofrequency treatment (TECAR therapy) can reduce pain and improve function and quality of life for people with low back pain caused by a herniated disc. It involves an exercise program along with the treatment.
AnkaraAges 20–60 - NCT07338110Recruiting
Achilles tendon surgery study
This study tracks people who have surgery to fix their Achilles tendon. It helps doctors learn more about how these surgeries go and how patients recover.
Paris, Île-de-France RegionAges 7 years+ - NCT07339137Recruiting
PRP injections for chronic knee osteoarthritis
This trial tests if platelet-rich plasma (PRP) injections into and around the knee joint can reduce pain and improve function for people with moderate knee osteoarthritis who haven't gotten relief from other treatments.
Ankara, ÇankayaAges 40–65 - NCT07338955Recruiting
Reliability study of upper limb disability questionnaire
This study is testing how well a questionnaire works for people with upper limb problems. It aims to understand if the survey reliably measures disability. You may be asked to fill out a form about your symptoms.
Karachi, SindhAges 18–45 - NCT07337642Recruiting
Comparing two types of hip replacement stems
This study compares two kinds of hip implant stems (one with a collar, one without) to see which works better for patients getting their first total hip replacement. If you are scheduled for a cement-free hip replacement due to arthritis, this trial may be a good fit.
Washington D.C., District of ColumbiaAges 18–99 - NCT07337772Recruiting
Comparing corticosteroid doses in knee replacement pain relief injection
This study compares different doses of a corticosteroid (an anti-inflammatory medicine) injected into the knee during total knee replacement surgery. The goal is to see which dose provides the best pain relief after surgery. It is for people having their first knee replacement due to osteoarthritis.
Fuzhou, FujianAges 18–100 - NCT07342426RecruitingPhase 4
Laser therapy for tennis elbow
This trial tests high and low dose laser therapy for people with tennis elbow (lateral epicondylitis) that started less than three months ago. It aims to see if laser treatment can reduce pain and improve healing.
Kaohsiung CityAges 18 years+ - NCT05450510Recruiting
Testing slow vs faster rehab for severe shoulder tears
This study compares two physical therapy rehab plans to see which helps people recover better after a severe, irreparable rotator cuff tear. It may help you find the pace of rehab that works best for your shoulder and daily function.
KırşehirAges 18–65 - NCT06862843Recruiting
Family eating habits and chronic inflammation study
This study looks at how eating habits and family health history relate to chronic inflammatory conditions like Crohn's disease, ulcerative colitis, and juvenile idiopathic arthritis. It aims to understand these links by studying families with a child or adult affected by these conditions, as well as healthy families.
Florence, ItalyAges Any age - NCT06861751Recruiting
Smartphone overuse and jaw proprioception in teens
This trial looks at how heavy smartphone use affects neck posture, neck muscle endurance, and jaw awareness in teenagers aged 17-19. It aims to understand if long-term phone use is linked to these physical changes.
Al MansurahAges 17–19 - NCT04884542Recruiting
Testing a knee replacement implant for total knee arthroplasty
This study looks at outcomes after surgery using the Multigen Plus H knee replacement system, sometimes with special add-on parts called AMF TT cones. It may help improve how well these knee implants work and how patients recover after total knee replacement.
GhentAges 18 years+ - NCT06729983Recruiting
Tendon lengthening during reverse shoulder replacement
This study tests whether slightly lengthening a tendon during reverse shoulder replacement improves outcomes. It's for adults getting their first reverse replacement at Loyola sites.
Maywood, IllinoisAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,508 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.