Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,599 recruiting studies in this area right now.
By phase
- Not applicable4,683
- Phase 21,187
- Phase 1568
- Phase 3457
- Phase 1/Phase 2366
- Phase 4228
- Phase 2/Phase 3110
Top conditions
- Colorectal Cancer478
- Pancreatic Cancer287
- Gastric Cancer283
- Hepatocellular Carcinoma256
- Esophageal Cancer189
- Rectal Cancer168
- Breast Cancer146
- Crohn Disease134
- Ulcerative Colitis129
- Colon Cancer114
- Hepatocellular Carcinoma (HCC)112
- Liver Cancer99
- Lung Cancer95
- Inflammatory Bowel Diseases94
- Pancreas Cancer91
- Ovarian Cancer89
- Esophageal Squamous Cell Carcinoma86
- Cystic Fibrosis77
Leading sponsors
- Fudan University101
- Sun Yat-sen University85
- Mayo Clinic75
- Second Affiliated Hospital, Zhejiang University, School of Medicine56
- Chinese University of Hong Kong55
- M.D. Anderson Cancer Center55
- Assistance Publique - Hôpitaux de Paris53
- Sixth Affiliated Hospital, Sun Yat-sen University51
- National Cancer Institute (NCI)49
- National Taiwan University Hospital45
Where studies are running
- California438
- Arizona189
- Texas140
- Alabama129
- Florida128
- New York120
- Massachusetts119
- Maryland88
- Ohio79
- Illinois69
Recruiting studies7,599 total
- NCT06802042Recruiting
Probiotic for constipation in pregnancy
This trial tests if a probiotic called Lactobacillus can help relieve constipation in pregnant women and improve gut health. It compares the probiotic to a placebo to see if it is safe and effective.
Beijing, Beijing MunicipalityAges 18–40 - NCT06800911Recruiting
Metacognitive beliefs in obesity
This study explores how thinking patterns and beliefs about one's own thoughts may be linked to obesity. It aims to understand the role of metacognition in people with severe obesity.
Oggebbio, VerbaniaAges 18–65 - NCT06800469Recruiting
Gut bacteria study in pancreatic cancer surgery patients
This trial looks at gut bacteria in people having surgery for pancreatic cancer. It aims to understand how these bacteria might affect recovery or treatment outcomes.
Bologna, BOAges 18 years+ - NCT07450144Recruiting
Chatbot to Help Reduce Alcohol in Fatty Liver Disease
This study tests a chatbot that helps people with fatty liver disease reduce how much they drink. If you drink regularly and are ready to change, this tool could support you.
Hong KongAges 18 years+ - NCT07451171RecruitingPhase 2
Comparing antibiotics for gut bacteria in children
This study compares three different antibiotics to treat small intestine bacterial overgrowth (an overgrowth of bacteria in the gut) in children in Bangladesh. It aims to find which antibiotic works best.
DhakaAges 1–2 - NCT07448077RecruitingPhase 2
Short radiation with immunotherapy for rectal cancer
This trial tests a combination of short-course radiation, chemotherapy, and an immunotherapy drug (Enlonstobart) for patients with a specific type of rectal cancer called pMMR. It aims to see if this approach can shrink tumors before surgery and improve outcomes.
Shijiazhuang, HebeiAges 18 years+ - NCT07451470Recruiting
Comparing two airway devices for stomach air in children during short surgeries
This trial compares two devices used to help children breathe during surgery (LarySeal Pro and Ambu AuraGain). It measures how much air gets into the stomach, which can cause discomfort. It is for children aged 6–12 having short elective surgeries (1 hour or less).
Cairo, Cairo GovernorateAges 6–10 - NCT07452601RecruitingPhase 2
Timing of immunotherapy infusion in chemo before surgery for esophageal cancer
This trial tests whether giving immunotherapy and chemotherapy at a specific time of day improves outcomes for people with esophageal cancer before surgery. It may help shrink the tumor and make surgery more effective.
Xi'an, ShannxiAges 18–75 - NCT07449091Recruiting
HBV undetectable equals untransmissible study
This study checks if having undetectable hepatitis B virus (HBV) means you cannot pass it to others. It tests this idea in people with chronic HBV who are on treatment, those not on treatment, and healthy controls.
New York, New YorkAges 18–65 - NCT07453186Recruiting
Ultrasound scans before weight loss surgery
This trial tests if two types of ultrasound scans can help see the gallbladder and liver better in people scheduled for weight loss surgery. It may lead to safer procedures.
EsbjergAges 18 years+ - NCT07447050RecruitingPhase 2
Riluzole to Prevent Chemo-Related Cognitive Problems
This pilot study tests whether the drug riluzole can help prevent the thinking and memory problems (often called 'chemobrain') that some people experience during chemotherapy. If you are about to start a chemo regimen containing an anthracycline or platinum drug, you may be able to join.
Orange, CaliforniaAges 18 years+ - NCT07449793Recruiting
PBC treatment response and long-term health outcomes
This research study tracks how well Primary Biliary Cholangitis (PBC) responds to standard medication (UDCA) and what happens to patients' health over time. It may help doctors understand which treatments work best for different people.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT07446257RecruitingEarly Phase 1
Combining THIO and cadonilimab for liver cancer surgery
This trial tests two drugs (THIO and cadonilimab) given before surgery to see if they help shrink liver cancer that can be removed. It is for people with early-stage liver cancer who are candidates for surgery.
Dallas, TexasAges 18 years+ - NCT07448753Enrolling by invitation
Testing for genetic causes of chronic intestinal blockage
This trial checks if a genetic test can find causes of a rare condition where the intestines don't move normally, causing blockages. It may help people with poor esophagus muscle function.
MilanAges 18 years+ - NCT07449208Recruiting
Esophagectomy leak risk registry study
This study follows people having surgery to remove part of the esophagus (esophagectomy) who are at higher risk for a leak where the esophagus is reconnected. The goal is to learn more about who develops leaks and how to prevent them.
Basking Ridge, New JerseyAges 18 years+ - NCT07450898Recruiting
Pancreatitis after blood clot removal procedure
This study looks at people who developed pancreatitis after a blood clot removal procedure. The goal is to understand what might have caused the pancreatitis.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07449897Recruiting
Gallstone removal during gallbladder surgery study
This study tests a method to remove bile duct stones during gallbladder surgery, aiming to treat both problems in one procedure.
OsloAges 18 years+ - NCT07450612Recruiting
Blood test and AI for early colorectal cancer detection
This study uses a simple blood test (liquid biopsy) and computer analysis to find early signs of colorectal cancer, precancerous growths, and Lynch syndrome. It aims to improve early detection and monitor for any remaining cancer after treatment.
Milan, LombardyAges 18 years+ - NCT07451483Recruiting
Ventral hernia after cytoreductive surgery: risks and treatment
This study looks at how common ventral hernias (bulges in the belly) are after a certain type of abdominal cancer surgery called cytoreductive surgery with or without heated chemotherapy. It also looks at what increases the risk and how these hernias are treated. If you've had this surgery, your experience can help doctors improve care.
Anderlecht, Brussels CapitalAges 18 years+ - NCT07445204Enrolling by invitation
Electrical stimulation for swallowing after stroke
This trial tests whether a gentle electrical stimulation technique on neck muscles can help improve swallowing in people who recently had a stroke. It may be a good option if you are still having trouble swallowing after your stroke.
IstanbulAges 18 years+ - NCT07449728Recruiting
Laser treatment for varicose veins with different wavelengths
This trial tests different types of laser energy to treat varicose veins. It looks at which wavelength works best for closing the faulty vein and preventing the disease from getting worse.
MoscowAges 18 years+ - NCT07450950Recruiting
Learning from patients before and after major cancer surgery
This trial looks at how people understand health information and what they expect before and after major cancer surgery. The goal is to help doctors better support patients by learning about their hopes and possible regrets.
Copenhagen, CopenhagenAges 18 years+ - NCT07451028Recruiting
Mouth training device for swallowing problems after stroke
This trial tests a device that strengthens mouth muscles to help people who have trouble swallowing after their first stroke. It may improve your ability to swallow safely.
Hammel, JutlandAges 18 years+ - NCT07452848Recruiting
Pringle maneuver's effect on gallbladder after liver surgery
This trial studies whether a technique called the Pringle maneuver (temporarily stopping blood flow to the liver during surgery) affects gallbladder health after liver surgery. It is for people having a liver tumor removed while keeping their gallbladder.
Hefei, AnhuiAges 18–85
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,599 recruiting gastroenterology studies from the U.S. registry right now, out of 11,991 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.