Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,908 recruiting studies in this area right now.
By phase
- Not applicable4,926
- Phase 21,188
- Phase 1584
- Phase 3466
- Phase 1/Phase 2396
- Phase 4237
- Phase 2/Phase 3111
Top conditions
- Colorectal Cancer492
- Gastric Cancer297
- Pancreatic Cancer292
- Hepatocellular Carcinoma284
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer147
- Crohn Disease144
- Ulcerative Colitis141
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)106
- Liver Cancer101
- Lung Cancer98
- Pancreas Cancer94
- Esophageal Squamous Cell Carcinoma89
- Ovarian Cancer88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University91
- Mayo Clinic74
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center58
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California463
- Arizona177
- Texas148
- Florida135
- Massachusetts127
- New York123
- Alabama122
- Maryland87
- Ohio80
- Pennsylvania72
Recruiting studies7,908 total
- NCT07265271Recruiting
Study to detect liver cancer early using blood tests
This study is looking for people with or without liver cancer to test a new way to find liver cancer early using blood or tissue samples. It aims to help catch the disease sooner.
Duarte, CaliforniaAges 18 years+ - NCT07186296Recruiting
Emerald blood test study for new cancer diagnosis
This study is testing a blood test that looks for signs of lung, breast, colorectal, pancreatic, or ovarian cancer. If you have just been told you might have one of these cancers and haven't started treatment yet, this study may be an option to help learn more about your cancer from a simple blood draw.
Long Beach, CaliforniaAges 45 years+ - NCT06630130RecruitingPhase 2
Surgery and drug therapy for advanced stomach cancer
This trial tests whether combining different drugs before and after surgery can help people with locally advanced stomach cancer that can't be removed right away. The goal is to see which combination works best to shrink the tumor and improve outcomes.
SeoulAges 19 years+ - NCT07051187RecruitingPhase 1
WGc0201 for chronic hepatitis B
This trial tests a new drug called WGc0201 in adults with chronic hepatitis B who have controlled their virus with standard antiviral pills. It aims to see if WGc0201 can further reduce hepatitis B surface antigen (HBsAg) levels.
Chengdu, SichuanAges 18–65 - NCT07678177Recruiting
Study of tegoprazan for patients with GERD
This study looks at how well and how safely the drug tegoprazan works for people with gastroesophageal reflux disease (GERD). It may help if you have symptoms like heartburn or acid reflux.
SeoulAges 19 years+ - NCT07549399RecruitingPhase 3
Radiation, Chemotherapy, and Immunotherapy for Rectal Cancer
This trial tests a combination of radiation, chemotherapy, and immunotherapy drugs before surgery for people with locally advanced rectal cancer. The goal is to shrink the tumor and improve outcomes for patients with higher-risk disease.
Guangzhou, GuangdongAges 18–75 - NCT07483658Recruiting
Salvage pelvic radiotherapy: 20 vs 25 sessions for recurring prostate cancer
This trial compares two schedules of pelvic radiotherapy for men whose prostate cancer has returned after surgery. Both schedules aim to control the cancer with fewer visits for one of them.
Gatineau, QuebecAges 18 years+ - NCT07347834Recruiting
Should you continue meds or have colitis surgery?
This trial studies whether continuing advanced medical treatments or having surgery (colectomy) is better for people with ulcerative colitis whose disease is active and hasn't improved after trying two or more advanced therapies.
Solna, Stockholm CountyAges 18 years+ - NCT07347951RecruitingPhase 2
New drug combo for rectal cancer patients who want to save their anus
This trial tests a combination of short-course radiation, chemotherapy, and two targeted drugs (Serplulimab and Bevacizumab) for people with a specific type of rectal cancer. It aims to see if this treatment can help shrink the tumor enough to avoid surgery and keep the anus.
Wenzhou, ZhejiangAges 18–75 - NCT07348211RecruitingPhase 1
Study of SIM0610 for advanced solid tumors
This trial tests a new drug called SIM0610 for people with advanced solid tumors that have stopped responding to standard treatments. The study aims to see if the drug is safe and effective.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT07349043RecruitingPhase 1
Spray chemotherapy for colon cancer spread in the belly
This trial tests a new way to give chemotherapy by spraying it into the belly during a minimally invasive surgery. It is for people whose colon or rectal cancer has spread inside the belly (peritoneal metastasis) but not to other organs.
Hangzhou, Other (Non U.s.)Ages 18–75 - NCT07349472RecruitingPhase 2
Pentoxifylline for ulcerative colitis
This trial tests if the drug pentoxifylline can help people with mild to moderate ulcerative colitis. It may offer a new treatment option for those not on other strong medications.
Al FayyumAges 18–70 - NCT07349654Recruiting
New stent method to reduce brain fog after TIPS procedure
This trial tests a modified stent placement technique during TIPS (a procedure to lower blood pressure in the liver) to see if it helps prevent confusion and memory problems that can happen afterward.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT07350460Recruiting
Comparing two pain blocks for hemorrhoid surgery
This study tests two types of numbing injections (a pudendal block and a sacral ESP block) to see which works better for pain after hemorrhoid surgery. If you're scheduled for this surgery, you might qualify to help find a better way to manage pain.
BellinzonaAges 18–80 - NCT07351669Recruiting
Spectral CT to check TACE response in liver cancer
This study uses a special type of CT scan (spectral CT) to see how well liver cancer has responded to a previous TACE treatment. If you've already had TACE for your liver cancer, this scan may help your doctors decide on the next steps, such as surgery or another procedure.
NanjingAges 18–75 - NCT07352280Recruiting
Immunotherapy before surgery for certain colorectal cancers
This trial tests a new immunotherapy drug (tislelizumab) given before surgery for people with stage II or III colorectal cancer that has a specific DNA repair problem (dMMR/MSI-High). The drug aims to shrink the tumor and improve treatment outcomes.
Beijing, UndefinedAges 18 years+ - NCT07353645RecruitingPhase 1/Phase 2
KRAS vaccine for colorectal and pancreatic cancer after surgery
This trial tests a new vaccine that targets KRAS mutations in patients with colorectal or pancreatic cancer after surgery and chemotherapy. The goal is to see if the vaccine can help prevent the cancer from coming back.
Nanjing, JiangsuAges 18–75 - NCT07353853Recruiting
Pre-packaged low-residue diet for colonoscopy prep in IBD
This trial tests if a special pre-packaged low-residue diet can improve bowel preparation for colonoscopy in people with inflammatory bowel disease (IBD). It aims to make the prep easier and more effective.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07354295Recruiting
Using AI to predict treatment response in esophageal cancer
This trial uses a combination of imaging and clinical data to see if a computer model can predict how well your treatment will work. It aims to help doctors better understand your cancer risk and choose the best treatment plan for you.
Wuhan, Other (Non U.s.)Ages Any age - NCT07354711RecruitingPhase 1/Phase 2
Study of 3H-10000 for advanced solid tumors
This trial tests a new drug called 3H-10000 for people with solid tumors that cannot be removed by surgery or have spread. The goal is to see if it is safe and works against cancer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07354919RecruitingPhase 2
Testing axelopran for advanced cancer patients on opioids
This trial tests if axelopran can help people with advanced prostate, breast, pancreatic, or lung cancer who are taking opioid pain medicines. It aims to see if the drug is safe and helps with bowel function.
Saint Louis Park, MinnesotaAges 18 years+ - NCT07355777Recruiting
Video tutorial for first colonoscopy preparation
This trial tests whether adding a short video tutorial to the usual verbal instructions helps people prepare better for their first colonoscopy. It aims to see if the video makes the preparation process easier and more effective.
LyonAges 18–80 - NCT07356531Recruiting
Thermosensitive Embolic Agent for Liver Cancer TACE
This trial tests a new heat-sensitive embolic agent used during TACE (a procedure that blocks blood flow to tumors and delivers chemotherapy directly to the liver) for primary liver cancer. It aims to see if the agent is safe and effective for patients who need TACE treatment.
Hefei, AnhuiAges 18–80 - NCT07358546RecruitingPhase 1
Test of efimosfermin alfa in adults with liver problems
This trial is for adults with liver cirrhosis (scarring) who have moderate to severe liver impairment. It studies how the body handles a new medicine called efimosfermin alfa, to see if it could be a safe treatment option. You may be able to join if your liver function is stable and you fall into a specific Child-Pugh class.
Rialto, CaliforniaAges 18–70
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,908 recruiting gastroenterology studies from the U.S. registry right now, out of 12,480 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.