Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,916 recruiting studies in this area right now.
By phase
- Not applicable4,936
- Phase 21,188
- Phase 1583
- Phase 3465
- Phase 1/Phase 2396
- Phase 4237
- Phase 2/Phase 3111
Top conditions
- Colorectal Cancer493
- Gastric Cancer298
- Pancreatic Cancer292
- Hepatocellular Carcinoma284
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer148
- Crohn Disease144
- Ulcerative Colitis140
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)107
- Liver Cancer101
- Lung Cancer99
- Pancreas Cancer94
- Esophageal Squamous Cell Carcinoma89
- Ovarian Cancer88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University91
- Mayo Clinic75
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center58
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California461
- Arizona174
- Texas148
- Florida135
- Massachusetts127
- Alabama123
- New York123
- Maryland87
- Ohio80
- Pennsylvania72
Recruiting studies7,916 total
- NCT07539727Recruiting
Intestinal ultrasound to predict Crohn's disease flare-ups
This study tests whether a special ultrasound of the intestines can predict when Crohn's disease will flare up again in patients whose disease is currently well-controlled. If successful, doctors could catch flare-ups earlier and adjust treatment before symptoms worsen.
Guangzhou, GuangdongAges 18–70 - NCT07540026Recruiting
Comparing Two Treatments for Bleeding Stomach Tumors
This trial tests two medications—tranexamic acid and sucralfate—applied during an endoscopy (a camera procedure) to stop bleeding caused by tumors in the upper digestive tract. The goal is to see which treatment works better at controlling the bleeding.
Tainan, Not Required For This CountryAges 18 years+ - NCT07540312Recruiting
Compression System for Moderate to Severe Irritable Bowel Syndrome
This trial tests a wearable compression device designed to help people with moderate to severe irritable bowel syndrome (IBS). The device applies variable pressure to the abdomen and may help reduce symptoms like abdominal pain, bloating, and bowel irregularities.
Kissimmee, FloridaAges 18–60 - NCT07540572RecruitingPhase 1
Testing IDE574 safety and effectiveness in advanced solid tumors
This early-stage trial tests a new drug called IDE574 to see if it is safe and effective in treating advanced cancers that have spread or stopped responding to standard treatments. The trial focuses mainly on hormone-receptor positive breast cancer, but also includes lung, prostate, and colorectal cancers.
Plantation, FloridaAges 18–99 - NCT07540637Recruiting
Study of how well patients take hepatitis B medication with app support
This study tests whether a smartphone app called HBVCare helps patients with chronic hepatitis B stick to their treatment plans. Researchers will track how well the app helps patients take their medicines on time and understand what makes treatment adherence easier or harder.
HanoiAges 18 years+ - NCT07542002RecruitingPhase 2
Chemotherapy and Radiation for Pancreatic Cancer Before Surgery
This trial tests a combination of four drugs (liposomal irinotecan, 5-fluorouracil, oxaliplatin, and adebrelimab) given with radiation therapy before surgery for pancreatic cancer that can be surgically removed or is borderline removable. The goal is to shrink the tumor and improve the chances of successful surgery.
NingboAges 18–75 - NCT07542171Recruiting
Outcomes after incomplete early colon cancer removal
This study follows patients who had early colon cancer removed by endoscopy (a camera procedure) but the removal was incomplete. Researchers will track what happens when patients either have surgery afterward or are closely watched instead, to understand the best next steps.
Guangzhou, GuangdongAges 18–75 - NCT07542652Recruiting
Microplastics and stomach cancer risk study
This research examines whether tiny plastic particles in the body are linked to stomach cancer development. Researchers will compare microplastic exposure in people with different stages of stomach issues—from inflammation to early changes to cancer—to understand if plastics play a role.
Xi'an, ShaanxiAges 18–75 - NCT07543744RecruitingPhase 1
Comparing RPH-030 to Vectibix for metastatic colorectal cancer
This trial tests whether a new drug called RPH-030 works similarly to an existing drug called Vectibix in treating advanced colorectal cancer that has spread. Both drugs will be given alongside chemotherapy (FOLFIRI) as a first-line treatment.
ArkhangelskAges 18 years+ - NCT07544433Recruiting
Breathing Training to Help Reduce Acid Reflux
This study tests whether special diaphragm breathing exercises (using the muscle below your lungs that controls breathing) can reduce acid reflux symptoms. You'll learn and practice these exercises over time to see if they help your GERD without needing more medication.
Changhua, Changhua CountyAges 20–80 - NCT07546565Recruiting
Bowel Prep Before Minimally Invasive Colon Cancer Surgery
This trial tests whether cleaning out your colon before surgery for early-stage colon cancer affects outcomes when surgeons use a minimally invasive (laparoscopic) approach. Researchers want to see if this prep step makes a difference in recovery and complications.
Ho Chi Minh City, Ho Chi MinhAges 18 years+ - NCT07547553RecruitingPhase 1/Phase 2
HH-009 for Advanced Liver Cancer with FGF19 Marker
This trial tests a new drug called HH-009 for advanced or inoperable liver cancer (hepatocellular carcinoma, or HCC) that has a specific genetic marker called FGF19. The drug is designed to target this marker and may help slow or shrink the cancer in people whose disease has gotten worse despite previous treatment.
Bengbu, AnhuiAges 18–75 - NCT07547787Recruiting
Long-term safety follow-up for cadonilimab study participants
This is a follow-up study for people who previously received cadonilimab (AK104), an experimental cancer drug, in an earlier clinical trial. Researchers will check in with you periodically to monitor your health and collect information about how you're doing long-term.
BeijingAges Any age - NCT07549724Recruiting
Assessment tools for swallowing problems from brain conditions
This study tests new ways to evaluate and measure swallowing difficulties caused by neurological conditions like stroke or Parkinson's disease. Participating helps researchers develop better tools to diagnose and monitor swallowing problems in patients with these conditions.
Venezia, ItalyAges 18–85 - NCT07549958RecruitingPhase 1
Gemcitabine with or without Pitavastatin for Advanced Pancreatic Cancer
This study tests whether adding pitavastatin (a cholesterol-lowering drug) to gemcitabine chemotherapy can help treat pancreatic cancer that cannot be surgically removed. You would join if your cancer hasn't grown worse after 2–4 rounds of gemcitabine.
Orange, CaliforniaAges 18 years+ - NCT07551375Recruiting
Fast MRI scan to diagnose gallbladder inflammation
This study tests whether a new type of quick MRI scan can reliably detect acute cholecystitis—sudden inflammation of the gallbladder. If it works well, doctors may be able to diagnose this condition faster and help patients get treatment sooner.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07551362RecruitingPhase 1/Phase 2
CAR-NK Cell Therapy for Advanced Gastric Cancer
This trial tests a new type of cell therapy (CAR-NK cells) designed to attack gastric and esophageal junction cancers that have specific markers on their surface. The cells are engineered to recognize two targets on your cancer cells, which may help your immune system fight the cancer more effectively.
Shenzhen, GuangdongAges 18–75 - NCT07551440Recruiting
Finding treatment targets in advanced gastric cancer
This study looks for specific genetic or molecular markers in advanced gastric cancer that has spread to other parts of the body. The goal is to identify which treatments might work best for each patient's individual cancer.
Hong KongAges 18–80 - NCT07551466Recruiting
AI tool to detect early stomach cancer from endoscopy images
This study tests an artificial intelligence tool that analyzes images taken during stomach endoscopy to help diagnose early-stage stomach cancer or precancerous changes. The goal is to improve how doctors identify and treat these lesions early, when treatment is most effective.
SuzhouAges 18–80 - NCT07552467Recruiting
PET Imaging Scan for Detecting Cancer Using New Radioactive Tracer
This study tests a new type of imaging scan (PET/CT or PET/MR) that uses a radioactive tracer to help doctors better detect and diagnose various cancers. The scan targets a specific protein found in tumors, which may help identify cancer more accurately than standard imaging.
Wuhan, HubeiAges 18 years+ - NCT07552701Recruiting
Pain relief methods after gallbladder removal surgery
This study compares two different nerve-blocking techniques to help manage pain after laparoscopic gallbladder surgery. Both methods use ultrasound guidance to deliver numbing medication near nerves, and the trial tests which approach works better for pain relief and overall recovery.
ÇorumAges 18–65 - NCT07553572Recruiting
Smartphone app to track cancer symptoms during treatment
This study tests a smartphone application designed to help you monitor and manage side effects and symptoms while you're receiving chemotherapy or other systemic treatment for breast cancer, colorectal cancer, or lymphoma. The app may help your doctors catch problems early and support you throughout your treatment.
Boston, MassachusettsAges 18 years+ - NCT07553663RecruitingPhase 1
Testing a new liver disease treatment for fatty liver
This study tests how your body processes a new medication called miricorilant, designed to help people with fatty liver disease (MASH). You'll have liver scans or recent biopsy results and metabolic conditions like diabetes or high blood pressure.
San Antonio, TexasAges 18–75 - NCT07554560Recruiting
Nutrition Support for Pancreatic Cancer Patients
This study tests a nutrition intervention for people with pancreatic cancer who are having trouble eating or absorbing nutrients. The goal is to help patients maintain strength and improve their quality of life during cancer treatment.
Philadelphia, PennsylvaniaAges 18 years+
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,916 recruiting gastroenterology studies from the U.S. registry right now, out of 12,516 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.