Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,879 recruiting studies in this area right now.
By phase
- Not applicable4,909
- Phase 21,183
- Phase 1583
- Phase 3465
- Phase 1/Phase 2392
- Phase 4235
- Phase 2/Phase 3112
Top conditions
- Colorectal Cancer494
- Gastric Cancer298
- Pancreatic Cancer292
- Hepatocellular Carcinoma283
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer146
- Crohn Disease144
- Ulcerative Colitis141
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)106
- Liver Cancer100
- Lung Cancer99
- Pancreas Cancer94
- Ovarian Cancer90
- Esophageal Squamous Cell Carcinoma88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University90
- Mayo Clinic75
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center59
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California463
- Arizona177
- Texas147
- Florida134
- Massachusetts128
- New York123
- Alabama122
- Maryland86
- Ohio78
- Pennsylvania72
Recruiting studies7,879 total
- NCT07578103Recruiting
Dairy vs Plant-based Yogurt for Weight and Bone Health
This study compares how dairy yogurt and plant-based yogurt affect weight, body composition, bone strength, and gut bacteria in postmenopausal women. It may help identify which type of yogurt is better for overall health during this life stage.
Québec, QuebecAges 40 years+ - NCT07575061Recruiting
Long-term study of survival factors in intestinal tuberculosis
This 15-year study follows patients with intestinal tuberculosis (a bacterial infection of the digestive tract) to understand what factors affect how long patients survive and live with this condition. The research may help doctors better predict outcomes and improve care for future patients.
Beijing, Beijing MunicipalityAges 18–100 - NCT07602452Recruiting
Pain Relief Methods After Colorectal Surgery
This study compares two different numbing techniques (nerve blocks) to help manage pain after open colorectal surgery. Both methods are injected near muscles in your abdomen to reduce the need for strong painkillers after surgery.
CairoAges 18–75 - NCT07544238Recruiting
Minimally Invasive Surgery for Ventral Hernia Repair
This study follows patients who undergo laparoscopic or robotic-assisted surgery to repair ventral hernias (bulges in the abdominal wall). Researchers track outcomes to understand how well these less-invasive approaches work compared to traditional open surgery.
Madrid, MadridAges 18 years+ - NCT07554716Recruiting
Timing of Tube Feeding and Body Rhythms
This study looks at how the timing of tube feeding (enteral nutrition) throughout the day affects your body's natural sleep and wake cycles. Researchers want to understand if adjusting when you receive nutrition might help improve your sleep and overall health.
Málaga, MálagaAges 18 years+ - NCT07554703Recruiting
Sleep Patterns and Home Nutrition Timing Study
This study looks at how your body's natural sleep-wake cycle interacts with nighttime home nutrition feeding. Researchers want to understand if timing adjustments could improve your sleep quality and overall health.
Málaga, MálagaAges 18 years+ - NCT07530809Recruiting
Time-Restricted Eating for Fatty Liver Disease
This study tests whether eating within a limited time window each day can improve fatty liver disease (a buildup of fat in the liver). If you have moderate-to-advanced fatty liver disease and are overweight, this trial might help you learn if changing when you eat—rather than what you eat—can reduce liver fat and improve your health.
Homburg, SaarlandAges 18–75 - NCT07559968Recruiting
Comparing two types of stents for bile duct cancer blockage
This study compares two different metallic stent designs to help keep bile ducts open in patients with advanced bile duct cancer. You would already have a temporary drainage tube in place and be scheduled for a permanent stent, so this trial tests which stent type works better.
Seoul, SeoulAges 19 years+ - NCT07568626Recruiting
Understanding Hospital Stays After Endoscopy Procedures
This study looks at why some older patients need to stay in the hospital longer after a common digestive procedure called ERCP. Researchers want to understand the factors that affect recovery time, which may help improve care for future patients.
Xiamen, FujianAges 65 years+ - NCT07592975Recruiting
Food with Fiber and B-Vitamins for Gut Health in Older Adults
This study tests whether adding special fibers (prebiotics) and B-vitamins to food can improve your gut bacteria, reduce inflammation, and support mental health. You'll eat fortified foods for several weeks while researchers track changes in your digestion and wellbeing.
Coleraine, County LondonderryAges 50 years+ - NCT07559578Recruiting
Colostomy Care Training for Nursing Students
This study tests a teaching method called simulation theory to help nursing students learn colostomy care (managing a surgically created opening for waste). The goal is to see if this hands-on training approach helps students feel more confident and prepared.
Kars, CentralAges 18 years+ - NCT07537660RecruitingPhase 2
Ear Stimulation and Steroids for Chemotherapy Nausea
This trial tests whether stimulating specific points on your ear, combined with a steroid medication, can reduce nausea and vomiting caused by two chemotherapy drugs (gemcitabine and paclitaxel) used to treat pancreatic cancer. The goal is to help you tolerate chemotherapy better.
HangzhouAges 18–85 - NCT07488013Recruiting
Early Regular Diet vs Clear Fluids After Colon Surgery
This study compares starting a regular diet soon after colon surgery versus a traditional clear-liquid diet. It aims to see which helps your bowel connection heal better and get you home sooner.
CairoAges 18–60 - NCT07488442Recruiting
Cognitive behavioral therapy for chronic constipation
This trial tests if cognitive behavioral therapy can help people with a specific type of chronic constipation called dyssynergic defecation. If you have had constipation for over a year and meet some specific tests, this therapy might improve your symptoms.
Ankara, YenimahalleAges 18–55 - NCT07481578Recruiting
Exercise and gut health study for active men
This study looks at how your training load affects your gut bacteria and how that relates to exercise performance and muscle health. It may help understand overreaching in healthy men.
Leuven, Vlaams BrabantAges 18–45 - NCT07520500Recruiting
Comparing two surgical techniques for high anal fistula
This trial compares two surgical methods (IFOC and LIFT) for treating high anal fistulas—abnormal tunnels that form near the anus. The goal is to determine which approach works better and has fewer side effects.
Cairo, Al-Manial, Cairo, EgyptAges 18 years+ - NCT07493863Recruiting
Virtual reality headset for endoscopy comfort
This trial tests if a virtual reality headset can help doctors feel more comfortable during certain scoping procedures. It looks at how the headset affects physical strain while doing colonoscopy, EUS, or ERCP.
Weston, FloridaAges Any age - NCT07448129Recruiting
Testing SUBMO for removing large colon growths
This trial tests a new liquid called SUBMO that doctors inject under large growths in the colon to make them easier to remove during a colonoscopy. It may help people who need a colon polyp or other lesion removed.
Barcelona, BarcelonaAges 18 years+ - NCT07382349Recruiting
Decision support tools for fatty liver disease
This study tests electronic tools to help doctors identify and care for patients with steatotic liver disease (fatty liver). If you have risk factors like diabetes or elevated liver enzymes, this trial may help improve your care.
Nashville, TennesseeAges 18 years+ - NCT07412379Recruiting
Predicting recovery after cancer surgery for older adults
This study looks at how older adults (65+) with digestive tract cancers respond to surgery aimed at a cure. Researchers want to see what factors affect recovery and quality of life after the operation.
BogotáAges 65 years+ - NCT07412613RecruitingPhase 3
Immunotherapy Before and After Surgery for MSI-H Colon Cancer
This trial tests a new immunotherapy drug (AK104) given before and after surgery for a specific type of colon cancer that is MSI-H or dMMR. The goal is to see if the drug helps shrink the tumor and prevent the cancer from coming back.
GuangzhouAges 18–75 - NCT07437755Recruiting
Guiding blood transfusions during procedures for cirrhosis
This study compares a special blood test (thrombelastometry) to standard tests to decide when to give blood products before invasive procedures in people with advanced liver cirrhosis. The goal is to see which method leads to better use of blood products and fewer complications.
Iași, IaşiAges 18 years+ - NCT07413029Recruiting
A study on people with PRSS1 gene changes
This study follows people who have a specific change (mutation) in the PRSS1 gene. The goal is to learn more about how this gene change affects health over time, which could help with future care.
Clichy-sous-BoisAges Any age - NCT07351253Recruiting
Nerve block comparison for open appendix surgery
This study tests two types of nerve blocks (Erector Spinae Plane Block and Lateral Transversus Abdominis Plane Block) to see which provides better pain relief after open appendectomy. This could help reduce pain and the need for stronger painkillers after surgery.
Cairo, Cairo GovernorateAges 21 years+
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,879 recruiting gastroenterology studies from the U.S. registry right now, out of 12,351 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.