Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,879 recruiting studies in this area right now.
By phase
- Not applicable4,909
- Phase 21,183
- Phase 1583
- Phase 3465
- Phase 1/Phase 2392
- Phase 4235
- Phase 2/Phase 3112
Top conditions
- Colorectal Cancer494
- Gastric Cancer298
- Pancreatic Cancer292
- Hepatocellular Carcinoma283
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer146
- Crohn Disease144
- Ulcerative Colitis141
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)106
- Liver Cancer100
- Lung Cancer99
- Pancreas Cancer94
- Ovarian Cancer90
- Esophageal Squamous Cell Carcinoma88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University90
- Mayo Clinic75
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center59
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California463
- Arizona177
- Texas147
- Florida134
- Massachusetts128
- New York123
- Alabama122
- Maryland86
- Ohio78
- Pennsylvania72
Recruiting studies7,879 total
- NCT07277907RecruitingPhase 3
Lubiprostone for slow-transit constipation in adults
This study tests whether lubiprostone (Amitiza) can help people with slow-transit constipation. If you have few bowel movements and tests show that stool moves slowly through your colon, this treatment may help you go more regularly.
Bishan, Chongqing MunicipalityAges 18 years+ - NCT07299513Recruiting
Study of airway and digestive fistulas in adults
This study looks at adults who had an abnormal connection between their airway and digestive tract, called an aerodigestive fistula, diagnosed between 2014 and 2023. It aims to understand these conditions better by reviewing patient data from the University Hospital of Strasbourg.
StrasbourgAges 18 years+ - NCT07325344Recruiting
Magnetically guided camera pill for small bowel exam
This trial tests a new way to move a camera pill through your small intestine using magnets. It is designed for people who already need a small bowel exam, and looks at how well the magnetic control works.
Jinan, ShandongAges Any age - NCT07303855Recruiting
Better fluid management after major abdominal surgery
This study compares two ways of giving fluids to people after major abdominal surgery in the ICU. It will see if using a measure of how much blood the heart pumps (cardiac index) is better than the usual method based on vein pressure.
Jakarta Pusat, DKI JakartaAges 18–65 - NCT07313293Recruiting
Foot reflexology for nausea after weight-loss surgery
This trial tests if foot reflexology can help reduce nausea after sleeve gastrectomy (a type of weight-loss surgery). You may join if you are scheduled for this surgery and do not have foot problems or take strong pain medications.
La Roche-sur-YonAges 18 years+ - NCT07346521Recruiting
Stomach cancer screening during routine colonoscopy
This study looks for early signs of stomach cancer and Barrett's esophagus (a precancerous condition) in people who are already getting a routine colonoscopy. By adding a quick upper endoscopy during the same visit, doctors can check for H. pylori infection and abnormal tissue changes without extra hassle.
ViennaAges 30 years+ - NCT07296692Recruiting
Does a protein drink change stomach emptying in older adults?
This study tests if a special drink with protein and carbs affects how fast the stomach empties in healthy older adults. It aims to improve nutritional care for elderly people.
Belo Horizonte, Minas GeraisAges 60–90 - NCT07345936Recruiting
Scoping to treat bile duct injuries after surgery
This trial tests using a scope (endoscope) to fix bile duct injuries that happen after surgery. It may help people with post-surgery leaks or blockages in the bile ducts.
StrasbourgAges 18 years+ - NCT07301853Recruiting
Long-term follow-up for liver transplant patients and living donors
This study follows liver transplant recipients and living donors over time to track their health outcomes. It aims to understand their recovery and long-term wellbeing.
Hangzhou, ZhejiangAges 18 years+ - NCT07324785Recruiting
Link between sugar substances and stomach problems in diabetes
This study looks at how sugar-related substances (called advanced glycation end products) might affect stomach muscle function in people with diabetes who have gastroparesis (slow stomach emptying). It compares them to people without diabetes to better understand the link.
Yangzhou, JiangsuAges 18–75 - NCT07253090Recruiting
Blood pressure and vein changes after varices treatment
This trial looks at how endoscopic treatment for enlarged veins in the esophagus (from liver disease) affects certain blood pressure readings. If you have cirrhosis and need treatment to prevent bleeding from these veins, you may be able to join.
HangzhouAges 18–80 - NCT07220382RecruitingPhase 4
Botox injections before large hernia surgery
This trial tests if getting Botox shots in the belly muscles before hernia surgery makes the repair easier and more successful. It is for adults who need a planned, open surgery for a large ventral hernia.
Cleveland, OhioAges 18 years+ - NCT07212361Recruiting
Restoring infant gut bacteria with mother's microbes
This study tests whether giving healthy newborns a special mix of their own mother's friendly bacteria can help build a healthy gut. It is for mothers who had a healthy pregnancy, plan to breastfeed, and live near Helsinki.
HelsinkiAges Up to 50 years - NCT07200518Recruiting
Probiotics after spine surgery study
This trial tests if taking probiotics after spinal surgery helps recovery. It is for adults with a herniated disc, spinal narrowing, or instability in the lower back or neck.
MariborAges 18 years+ - NCT07190183Recruiting
Washed microbiota transplant for food intolerance
This trial tests a treatment called washed microbiota transplantation for people with food intolerance. It may help reduce symptoms by restoring healthy gut bacteria.
Nanjing, JiangsuAges Any age - NCT07219784Enrolling by invitation
Abdominal binders for feeding in preterm babies on breathing support
This study tests whether a soft abdominal binder (a wrap around the belly) helps preterm babies on breathing support keep their milk feeds going without interruptions. It might help reduce pauses in feeding and support growth.
Albany, New YorkAges Up to 1 year - NCT07195331RecruitingPhase 4
Comparing dye doses for clearer bile duct images during gallbladder surgery
This trial tests two different doses of a special dye (indocyanine green) to see which one gives surgeons a clearer view of the bile ducts during gallbladder removal. The goal is to help make the surgery safer and reduce the risk of injury.
Salamanca, SalamancaAges 18 years+ - NCT07147335Recruiting
Blood test for early liver cancer warning in cirrhosis
This study looks at whether a blood test for a protein called AKR1B10 can help give early warning of liver cancer (hepatocellular carcinoma) in people with cirrhosis. If you have cirrhosis or chronic hepatitis and are between 18 and 75 years old, you may be able to join.
Hengyang, HunanAges 18–75 - NCT07155850Recruiting
Testing YntraDose before chemotherapy for advanced pancreas cancer
This trial tests a new treatment called YntraDose, given directly into the pancreas tumor before standard chemotherapy. It is for people with locally advanced pancreatic cancer that cannot be removed by surgery.
RomaAges 18 years+ - NCT07115134Recruiting
New dressing for feeding tube after placement
This trial tests a new type of dressing (bandage) designed to keep a gastrostomy feeding tube secure after it is placed in the stomach. It may help reduce movement and improve healing for children who have just had this surgery.
Washington D.C., District of ColumbiaAges 7–21 - NCT07135362Recruiting
Probiotic for improving constipation in adults
This trial tests a probiotic supplement to see if it helps improve bowel function in people with constipation. If you have functional constipation (not caused by another illness), this study may be a good fit.
TaipeiAges 18–65 - NCT07106424Recruiting
Early screening study for multiple gastrointestinal tumors
This study is looking for people aged 40-75 who have never had cancer to participate in early screening for gastrointestinal tumors. The goal is to find cancers early when they are easier to treat.
Jinan, ShandongAges 40–75 - NCT07178626Enrolling by invitation
Biomarkers and feeding tolerance in ICU patients
This study looks at whether certain biomarkers and stomach motility measurements can help predict feeding intolerance in critically ill patients who cannot eat by mouth. It aims to improve how patients are fed in the ICU.
ChangchunAges 18 years+ - NCT07152405RecruitingPhase 3
New drug vs. chemo for HER2+ stomach cancer
This trial tests a new targeted drug, BL-M07D1, against standard chemotherapy for people with HER2-positive stomach or gastroesophageal junction cancer that has spread. The goal is to see if BL-M07D1 works better than standard chemo.
Harbin, HeilongjiangAges 18–75
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,879 recruiting gastroenterology studies from the U.S. registry right now, out of 12,351 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.