Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,879 recruiting studies in this area right now.
By phase
- Not applicable4,911
- Phase 21,185
- Phase 1581
- Phase 3465
- Phase 1/Phase 2391
- Phase 4235
- Phase 2/Phase 3111
Top conditions
- Colorectal Cancer491
- Gastric Cancer296
- Pancreatic Cancer289
- Hepatocellular Carcinoma283
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer146
- Crohn Disease144
- Ulcerative Colitis141
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)106
- Liver Cancer100
- Lung Cancer97
- Pancreas Cancer94
- Esophageal Squamous Cell Carcinoma88
- Ovarian Cancer88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University90
- Mayo Clinic75
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center58
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California461
- Arizona177
- Texas149
- Florida134
- Massachusetts128
- New York123
- Alabama122
- Maryland85
- Ohio79
- Pennsylvania72
Recruiting studies7,879 total
- NCT02960737Recruiting
Training for swallowing problems after stroke
This trial studies whether a specific oral training program can improve swallowing after a stroke. It’s mainly for people whose swallowing trouble has lasted for several weeks after their stroke.
UmeåAges 18 years+ - NCT02966483Recruiting
Transanal or laparoscopic surgery for rectal cancer
This trial compares two surgical approaches to remove rectal cancer tissue while aiming to preserve cure chances. It may help you see which approach fits your tumor location and health situation best.
Beijing, Beijing MunicipalityAges 18–75 - NCT02972372Recruiting
Compare chemoradiation with surgery for esophageal cancer
This study compares two treatment approaches for certain locally advanced esophageal cancers: chemoradiation (chemo plus radiation) versus esophagus surgery. It may help find which option works better to control the cancer and improve outcomes.
Anyang, HenanAges 18–75 - NCT02997293Recruiting
Enhanced recovery after colorectal surgery care program
This study looks at whether a structured “enhanced recovery” plan around the time of colorectal surgery improves outcomes. Because it focuses on a specific group of surgeries done at a specific hospital during certain dates, it may be mainly for people whose surgeries match those records.
Little Rock, ArkansasAges 18 years+ - NCT03001362Recruiting
Wait-and-see treatment for people with rectal cancer
This study tests a “wait-and-see” approach instead of immediate surgery for certain rectal cancers, aiming to avoid unnecessary operations. It may help people who are medically able to stay under close monitoring and only have surgery if needed.
Montreal, QuebecAges 18–90 - NCT03025074Recruiting
Blood sample bank for liver disease research
This study collects blood samples to build a “biobank” (a stored library of samples) for researchers studying liver diseases like hepatitis, fatty liver disease, and liver cancer. It may help future testing and treatments by allowing scientists to study patterns in people with and without liver conditions.
Buffalo, New YorkAges 7 years+ - NCT03026140RecruitingPhase 2
Tested immune therapy before surgery for early colon cancer
This Phase 2 trial tests immune “checkpoint” medicines (and combinations) given before colon surgery to see if they can better control early colon cancer. It is aimed at people with non-metastatic colon cancer and certain tumor markers.
AmsterdamAges 18 years+ - NCT03047369Recruiting
Myelin brain disorder research biobank for samples and data
This study collects brain-related medical information and biological samples to help researchers better understand leukodystrophies and other white-matter brain disorders. It may help future diagnosis and treatments by building a valuable “biobank” of patient data and samples.
Los Angeles, CaliforniaAges Any age - NCT03050268Recruiting
Study of childhood cancer risk in families
This study looks at inherited (family) risk for childhood cancers, including families with early cancers or known cancer risk conditions. It may help researchers understand why some children get cancer and improve future risk detection and care.
Memphis, TennesseeAges Any age - NCT03052283Recruiting
Abdominal symptom score test for people with cystic fibrosis
This trial helps create and check a patient-friendly questionnaire that measures abdominal (belly) involvement in cystic fibrosis. It may help your care team better track symptoms over time.
Brandenburg an der HavelAges Any age - NCT03061435Recruiting
Screening for anal cancer after high-grade vulvar changes
This trial checks whether anal cancer screening is useful for women age 40 and older who previously had high-grade vulvar pre-cancer (VIN 2/3) or vulvar cancer. It may help find serious problems earlier in people at higher risk.
Toronto, OntarioAges 40 years+ - NCT03097952Recruiting
Study of people with long-term hepatitis B in real life
This “real-life” study follows people with chronic hepatitis B to better understand their health over time. It may help researchers learn which factors affect outcomes in everyday care.
Changzhou, JiangsuAges Any age - NCT03099850Recruiting
Studying chronic pancreatitis using follow-up tests
This study follows people with chronic pancreatitis to learn more about the disease and how to better diagnose it. You may have research-related scans or procedures and will be asked to stay in follow-up over time.
Houston, TexasAges 18–75 - NCT03124212Recruiting
Genetic testing guidance for inherited breast, ovarian, or colon cancer risk
This study helps people in Switzerland who already have a known inherited cancer gene change understand what it means for them and their family. It focuses on people with specific known mutations related to hereditary breast/ovarian cancer and Lynch syndrome.
Fribourg, Canton of FribourgAges 18 years+ - NCT03125343Recruiting
Watch-and-wait after rectal cancer treatment for select patients
This study looks at whether some people with rectal cancer can safely avoid immediate surgery after (chemo)radiation, instead closely monitoring their response. It may help some patients reduce treatment burden if the cancer fully responds.
GothenburgAges 18 years+ - NCT03131427Recruiting
Registry for inherited liver and metabolism-related conditions
This is a study that collects health information and samples (if applicable) from people with certain genetic or metabolic liver diseases. It may help doctors better understand these conditions and improve future care.
Beijing, Beijing MunicipalityAges Any age - NCT03151473Recruiting
Study of adults with fatty liver and NASH over time
This is a long-term study that follows adults who are being managed for fatty liver (NAFL) or NASH to learn how these conditions change over time. It may help researchers better understand what to expect and how care decisions could be improved.
Hong KongAges 18 years+ - NCT03167437RecruitingPhase 1/Phase 2
Vorinostat for uncontrolled Crohn’s or ulcerative colitis
This early-phase study tests vorinostat to reduce gut inflammation in people with moderate-to-severe Crohn’s disease, ulcerative colitis, or certain colitis patterns linked to chronic granulomatous disease (CGD). It also looks at whether the study’s consent process is clear and understood before starting treatment.
Bethesda, MarylandAges 18–65 - NCT03175224RecruitingPhase 2
Test drug APL-101 for lung or other tumors with MET changes
This Phase 2 study tests APL-101 to shrink advanced cancers that have certain MET-related changes, including specific MET mutations, MET gene amplification, or MET fusions. It may help people whose tumors have run out of standard treatment options.
Los Angeles, CaliforniaAges 18 years+ - NCT03183661Recruiting
Follow-up study for people previously given ALLO-ASC-CD
This study checks the long-term safety of ALLO-ASC-CD in people who already received it in an earlier phase 1 trial. It may help confirm that the treatment remains safe over time.
SeoulAges 18–65 - NCT03190538Recruiting
Study of fatty liver inflammation in Chinese children
This trial looks at nonalcoholic steatohepatitis (fatty liver with inflammation) in children. It is meant to test whether a new approach can help improve this liver problem without being caused by alcohol or other known liver diseases.
BeijingAges 1–18 - NCT03190941RecruitingPhase 1/Phase 2
T-cell therapy for HLA-A11:01 and KRAS G12V tumors
This trial tests a custom immune-cell treatment made from your blood that targets the KRAS G12V change in certain cancers. It is for people with advanced cancer who have already tried standard treatments, and it may help your immune system recognize and attack tumor cells.
Bethesda, MarylandAges 18–72 - NCT03198546RecruitingPhase 1
CAR T therapy for advanced liver cancer with GPC3
This Phase 1 study tests a personalized immune-cell treatment (CAR T cells) for advanced liver cancer that has the GPC3 protein. It aims to see whether these engineered cells can find and kill cancer cells safely and help shrink the cancer.
Guangzhou, GuangdongAges 18–75 - NCT03200379Recruiting
Taiwan registry for people treated for hepatitis C
This registry is for people in Taiwan who have received direct-acting antiviral (DAA) treatment for hepatitis C. It collects health information to better understand outcomes and care, and you can join if you agree to participate and sign consent.
Kaohsiung CityAges Any age
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,879 recruiting gastroenterology studies from the U.S. registry right now, out of 12,372 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.