Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,366 recruiting studies in this area right now.
By phase
- Not applicable975
- Phase 2167
- Phase 398
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia72
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Allergic Rhinitis23
- Nasopharyngeal Carcinoma (NPC)23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke19
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)16
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University58
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen10
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida29
- Massachusetts21
- Illinois20
- Arizona17
- Texas17
- Colorado16
- Alabama15
Recruiting studies1,366 total
- NCT06920368Recruiting
Preventing complications after nose surgery
This trial tests different methods to reduce complications after septoplasty, a surgery to fix a crooked nasal septum. It may help if you have a deviated septum that causes symptoms like trouble breathing.
TantaAges 16–60 - NCT05665244Recruiting
Cryotherapy for long-lasting cough from nerve signals
This trial tests a cold-treatment procedure (cryotherapy) to treat a stubborn cough caused by nerve signaling (not infections or common allergy/acid problems). It may help people whose cough has lasted at least 8 weeks and who have already tried to rule out other causes.
Dallas, TexasAges 18 years+ - NCT07368361Recruiting
Comparing surgery techniques for severe sinusitis with polyps
This study compares two different surgical techniques for treating severe sinusitis with nasal polyps. It's for people who have tried other treatments but still have symptoms.
Egypt, KafrelsheikhAges 18–75 - NCT07368179Enrolling by invitation
Neck Access Study for Kids
This study tests how doctors get emergency access to a child's neck. It may help doctors find the best method for fragile kids.
BernAges 25–65 - NCT07367568Recruiting
Nerve block comparison for mastectomy pain relief
This trial compares two types of nerve blocks to help manage pain during and after modified radical mastectomy. You may qualify if you are a woman between 18 and 65, have a healthy weight, and are scheduled for this surgery.
CairoAges 18–65 - NCT03649048Recruiting
Weekly low-dose or high-dose cisplatin with radiation for head and neck cancer
This trial compares two cisplatin dosing schedules (weekly low-dose vs higher dose less often) given alongside radiation for certain head and neck cancers. It’s testing which schedule works well while keeping side effects manageable during planned, curative-intent radiation.
Hamilton, OntarioAges 18 years+ - NCT04917367Recruiting
Treats confirmed foreign bodies outside the throat and esophagus
This trial focuses on people whose foreign body is found during surgery in an area outside the throat (pharynx) and esophagus. It tests how to diagnose and treat these situations after surgery confirms what was present.
Hangzhou, ZhejiangAges 18–70 - NCT06985784Recruiting
Virtual reality for head and neck cancer patients and caregivers
This study tests whether using virtual reality can help reduce depression, anxiety, and pain in people with head and neck cancer and their caregivers. You and your caregiver may be able to use VR headsets together as part of your treatment.
Duarte, CaliforniaAges 18 years+ - NCT04792034RecruitingPhase 3
Nasal medicine study for teens having nose procedures
This Phase 3 study tests how two different nasal solutions work in the body, and checks their safety and side effects. It involves teens who are already scheduled for a diagnostic procedure or surgery that goes through the inside of the nose.
Columbia, South CarolinaAges 12–18 - NCT07487636Enrolling by invitation
4DryField PH in head and neck surgery
This trial tests if 4DryField PH, a substance used to control bleeding, helps patients having head and neck surgery. It aims to see if it reduces complications.
Taichung, TaiwanAges 18 years+ - NCT07327710Enrolling by invitation
Brain-Computer Interface and Electrical Stimulation for Facial Paralysis
This trial tests a non-invasive treatment that combines a brain-computer interface with mild electrical stimulation to help people with one-sided facial paralysis regain movement. It aims to improve facial muscle function by retraining the brain and muscles together.
Changzhou, JiangsuAges 18–75 - NCT06338995RecruitingPhase 3
Lebrikizumab for nasal polyps and sinusitis
This trial tests a new injectable medicine (lebrikizumab) for people with chronic sinusitis and nasal polyps that steroid treatments haven't controlled. It aims to reduce polyp size and improve breathing, smell, and congestion.
Birmingham, AlabamaAges 12 years+ - NCT07370129Enrolling by invitation
Numbing injection for pain after tonsil surgery
This study tests a numbing injection near a nerve in your nose to see if it can reduce pain and help you recover faster after tonsillectomy. It is a non-drug approach that may offer an alternative to strong pain medicines.
Ankara, AnkaraAges 12 years+ - NCT06792188Recruiting
Using a smartwatch to predict sleep apnea
This trial tests if a smartwatch can help predict sleep apnea in people who have symptoms like snoring or daytime sleepiness. It may offer a simpler way to identify the condition.
SeoulAges 22–85 - NCT07317947Recruiting
Nasal tip shaping with a cartilage graft in first-time rhinoplasty
This trial tests a surgical technique that uses your own nasal cartilage to improve the shape and position of your nasal tip. It's for people having their first rhinoplasty (nose job) for cosmetic or breathing reasons.
Kafr ash ShaykhAges 18–60 - NCT05214092Enrolling by invitation
Study brain changes after surgery in teens and young adults
This study looks at how a brain area involved in hearing and language contributes to recovery after medically needed surgery. It may help doctors better understand post-op outcomes using language and hearing-related brain measurements.
Pittsburgh, PennsylvaniaAges 13–25 - NCT07571889Recruiting
Numbing spray to reduce Botox injection pain for chronic migraine
This study tests whether a numbing spray applied inside the nose before Botox injections can reduce injection pain in people with chronic migraine. The goal is to make the treatment more comfortable without affecting how well it works.
East Providence, Rhode IslandAges 18 years+ - NCT07307833Enrolling by invitation
Immune therapy and its effect on balance
This study checks if certain immune therapy drugs affect your balance or inner ear function. It involves people starting treatment with one or two of these drugs for cancer.
Scottsdale, ArizonaAges 18 years+ - NCT07300800Recruiting
PRP injection for voice after vocal cord surgery
This trial tests if injecting platelet-rich plasma (PRP) during vocal cord surgery helps your voice heal faster and better. It is for adults with benign growths like polyps or nodules that haven't improved with voice therapy.
Banī Suwayf, EgyptAges 18–50 - NCT07295548Recruiting
Can head and neck flap patients skip the ICU?
This trial compares whether patients recovering from head and neck cancer flap surgery need to stay in the intensive care unit (ICU) or can be safely cared for on a regular surgical ward. The goal is to see if a less intensive recovery is safe and equally effective.
Pavia, LombardyAges Any age - NCT07370337RecruitingPhase 2
Chemotherapy plus immunotherapy for ear canal cancer
This trial tests combining chemotherapy with the immunotherapy drug tislelizumab for advanced squamous cell carcinoma of the ear canal. It may help shrink tumors that haven't spread to other parts of the body.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07282483RecruitingPhase 2
Chinese medicine mouthwash for radiation mouth sores
This trial tests whether a traditional Chinese medicine mouthwash and oral liquid can help prevent or reduce mouth sores caused by radiation therapy for head and neck cancer. If you are getting radiation and are at risk for these painful sores, this study might offer you extra relief.
Chengdu, SichuanAges 18–65 - NCT07175779Recruiting
Comparing video calls vs. in-person visits for kids' surgery checkups
This trial tests whether a video call before surgery works as well as an in-person hospital visit for checking breathing risks in children getting their tonsils or adenoids removed. It may help families avoid extra trips to the hospital.
Bellinzona, Canton TicinoAges Up to 16 years - NCT06877897Enrolling by invitation
Ultrasound vs speech therapist for NG tube removal decision
This study is testing whether a simple ultrasound of the neck (called submental ultrasound) can help doctors decide when it's safe to remove a nasogastric (NG) tube, compared to a speech therapist's evaluation. If you have an NG tube that was placed due to a recent illness and are now recovering, this trial may help find a more reliable way to know when you can safely eat by mouth again.
Taipei, TaipeiAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,366 recruiting otolaryngology studies from the U.S. registry right now, out of 2,207 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.