Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT07525505Recruiting
Nigella Sativa Oil for Itchy, Inflamed Ear Canal
This trial tests whether Nigella sativa (black seed) oil can safely treat eczematous otitis externa—a condition causing itching, discomfort, and drainage in the ear canal. Researchers want to see if this natural oil works as well as standard treatments.
Istanbul, FatihAges 18 years+ - NCT07533071Recruiting
Study of Timing in Getting Hearing Aid Help
This research examines how delays in getting hearing aids or other listening devices affect people's everyday communication and quality of life. Understanding this may help doctors better support people with hearing loss.
Chicago, IllinoisAges 18 years+ - NCT07531810Recruiting
Nose Surgery Recovery and Patient Satisfaction Study
This study tracks how patients feel and function after nose surgery that uses a piece of cartilage (septal extension graft) to reshape the nose. Researchers want to understand both the benefits and any complications to improve future care.
Sivas, SivasAges 18 years+ - NCT07532538Recruiting
Machine learning tool to predict head and neck cancer risk
This study tests a computer program designed to help doctors predict which head and neck lesions (abnormal tissue growths) might be cancerous. Researchers will use your medical information and throat imaging to teach the program, which could help catch cancer earlier.
Nanjing, JiangsuAges 18–100 - NCT07533864Recruiting
Swallowing Support After Neck Surgery
This trial tests an approach to help patients who develop swallowing difficulties after front-of-neck spine surgery. Researchers will track swallowing problems and test whether a specific care method reduces symptoms.
Hamilton, OntarioAges 18 years+ - NCT07527780Recruiting
Sound Sensitivity Study in Active Teachers
This study explores how common sound sensitivity issues are among teachers. Researchers want to understand if certain sounds bother teachers more than others, and whether this affects their work or well-being.
ÇorumAges 22–45 - NCT07528183RecruitingPhase 2
Immunotherapy after chemo and radiation for recurrent nose cancer
This trial tests whether maintenance immunotherapy (PD-1 inhibitor) followed by delayed salvage radiation therapy can help keep your cancer under control after you have already responded to initial chemo-immunotherapy. It is for people with recurrent nasopharyngeal carcinoma that has come back in the nose or neck area, but has not spread to distant organs.
Fuzhou, FujianAges 18–70 - NCT06642324Recruiting
HPV and genetics in head and neck cancer study
This study looks at how HPV infection and genetic changes relate to head and neck squamous cell carcinoma. If you have this type of cancer, joining could help doctors learn more about the disease and improve future treatments.
Dhaka, Dhaka DivisionAges 18 years+ - NCT07518069Recruiting
Understanding Genes and Biology in Menière's Disease
This research study investigates the genetic and biological factors that cause Menière's disease—a condition affecting the inner ear that causes dizziness, hearing loss, and ear fullness. By studying these factors, researchers hope to better understand why some patients experience different symptoms and potentially improve future treatments.
Milan, ItalyAges 18 years+ - NCT07524452RecruitingPhase 3
Becotatug vedotin plus immunotherapy for head and neck cancer
This trial tests a new combination of two drugs—becotatug vedotin (a targeted therapy) and a PD-1 inhibitor (an immunotherapy)—given before surgery to treat advanced head and neck squamous cell carcinoma. The goal is to shrink tumors and improve surgical outcomes for patients with specific cancer markers.
Zhuhai, GuangdongAges 18–75 - NCT07517926Recruiting
Chewing gum and cold water gargle after lung breathing tube procedure
This study tests whether chewing gum and gargling with cold water can reduce sore throat and other discomfort after a bronchoscopy—a procedure where doctors look inside your airways with a thin camera. If it works, it could be a simple, safe way to feel better after the procedure.
AnkaraAges 18 years+ - NCT07515781Recruiting
VivaStent for Pulsatile Tinnitus Caused by Vein Narrowing
This study tests a stent (a small metal tube) placed in a narrowed vein in the brain to treat pulsatile tinnitus—a rhythmic ringing or whooshing sound in one ear that matches your heartbeat. The stent may improve blood flow and reduce or stop the sound.
ParisAges 18 years+ - NCT07507578Recruiting
Biology study for head and neck adenoid cystic carcinoma
This study uses advanced tests on tissue and blood samples to understand why adenoid cystic carcinoma (a type of head and neck cancer) spreads. It aims to find new clues that may help improve future treatments.
MilanAges 18 years+ - NCT07513077Recruiting
Hearing Loss Prevention Program for Primary School Children
This study tests whether a hearing protection education program called HoorToren helps 11–12 year old children in Dutch schools prevent noise-induced hearing loss. The program teaches kids about protecting their ears from loud sounds.
RotterdamAges Any age - NCT07509788Recruiting
Studying hearing with two ears in kids with cochlear implants
This trial looks at how hearing with both ears helps children with cochlear implants listen more easily and think better. It compares kids with implants to those with normal hearing.
Guangzhou, GuangdongAges 6–18 - NCT07510984Recruiting
Heterotopic gastric mucosa and quality of life study
This study looks at how a condition called heterotopic gastric mucosa (HGM), which is stomach tissue in the wrong place in the esophagus, affects symptoms and quality of life. If you are scheduled for an upper endoscopy and are at least 18, you may be able to join.
Bottrop, North Rhine-WestphaliaAges 18 years+ - NCT07511998Enrolling by invitation
Comparing endotracheal tube sizes to reduce sore throat after surgery
This study compares different sizes of a specialized breathing tube (endotracheal tube) used during surgery to see which size causes less sore throat afterward. If you're having elective surgery under general anesthesia, this trial may help reduce your post-surgery discomfort.
Daegu, DaeguAges 20–70 - NCT07500532Recruiting
Testing an app for childhood asthma and ear/nose/throat issues
This study tests an app that helps doctors check kids with asthma or common ear/nose/throat problems. It’s for children who get care at the University of Arizona and have a device to run the app.
Tuscon, ArizonaAges 3–17 - NCT07503613Enrolling by invitation
Long-term follow-up for AAVAnc80 gene therapy
This study follows people who already received the experimental AAVAnc80-antiVEGF gene therapy for vestibular schwannoma. It monitors long-term safety and effects of the treatment.
Dallas, TexasAges 18 years+ - NCT07505667Recruiting
Yiyuancong for sudden hearing loss
This trial tests a medicine called Yiyuancong for people who recently lost hearing in one ear suddenly. If you are between 18 and 60 years old and your hearing loss started within the last 3 days, this study may be an option.
Guangzhou, GuangdongAges 18–60 - NCT07499791RecruitingPhase 2
Absorbable stent for recurrent tear duct infection
This trial tests a new type of dissolvable stent that slowly releases medicine to treat chronic tear duct infections that have come back after previous surgery. It may help people who need another treatment option.
Beijing, Beijing MunicipalityAges 18–65 - NCT07506408Recruiting
Online listening training for adults with hearing difficulties
This study tests two types of online listening exercises that may help improve how well you understand speech in noise, even for people who normally use hearing aids. You'll practice from home and researchers will check if it helps your hearing, thinking, and everyday conversations.
Nottingham, NottinghamshireAges 18 years+ - NCT06767267Recruiting
Study of ear infection in children
This study looks at children with a certain type of ear infection to learn more about it. It helps doctors understand the condition better.
BolognaAges Up to 14 years - NCT06657690RecruitingPhase 2
New drug combo for advanced nasopharyngeal cancer after immunotherapy
This trial tests a combination of two drugs, irinotecan liposome and S-1, for people with a type of nose and throat cancer that has spread or come back after treatment with immunotherapy (PD-1/L1 inhibitors). The goal is to see if this new combination can help when standard treatments have stopped working.
Zhuhai, GuangzhouAges 18–70
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.