Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT07577232Recruiting
Ultrasound imaging for diagnosing throat abscesses
This trial tests whether using ultrasound (sound wave imaging) through the mouth helps doctors better diagnose a throat abscess—a pocket of infection near the tonsil. The goal is to see if this imaging method improves diagnosis accuracy and treatment decisions.
CopenhagenAges 18 years+ - NCT07569939Recruiting
Treatment options for sore throat from viral infection
This study tests different treatments to help ease sore throat pain and symptoms caused by viral throat infections. It aims to find the best way to relieve discomfort when you have pharyngitis, tonsillitis, or a viral sore throat that started recently.
Clermont-FerrandAges 18–70 - NCT07569952Recruiting
Nerve Block to Improve Surgical Field in Pituitary Surgery
This trial tests whether blocking a specific nerve in the face (sphenopalatine ganglion) during pituitary tumor surgery improves the surgeon's view and reduces bleeding. Pituitary adenomas are non-cancerous tumors in the brain that are removed through the nose using a camera.
CairoAges 1.8 years–60 years - NCT06665971RecruitingPhase 4
Dupilumab for esophagus muscle function in EoE
This trial tests if dupilumab, a weekly injection, can improve the muscle function of the esophagus in people with eosinophilic esophagitis (EoE) who haven't gotten better with acid-reducing medications. Researchers want to see if it helps with swallowing and reduces inflammation.
La Jolla, CaliforniaAges 22 years+ - NCT04717388Recruiting
Study brain and feelings in people with tinnitus
This study looks at how tinnitus affects the brain, thinking, and emotional well-being. It compares people with chronic tinnitus to people without tinnitus (including a group related to a specific type of epilepsy surgery).
ParisAges 18 years+ - NCT06733948RecruitingPhase 2
Dental stent to protect taste during NPC radiation
This trial tests whether a custom-fitted dental stent (like a mouthguard) can help protect your sense of taste during radiation and chemotherapy for nasopharyngeal cancer. If you qualify, you'll receive either standard care or the stent, and your taste changes will be tracked.
SingaporeAges 21–100 - NCT04296097Recruiting
Deep brain stimulation for severe, steady disabling tinnitus
This study tests whether deep brain stimulation (a device that sends controlled signals to the brain) can reduce severe, constant tinnitus that has not improved with usual treatments. It may help lower the loudness distress and improve daily quality of life for people whose tinnitus is especially disabling.
GrenobleAges 18–75 - NCT07565740RecruitingPhase 1
Vaccine plus immunotherapy for newly diagnosed HPV-positive throat cancer
This trial tests a new nasal vaccine combined with an immunotherapy drug (tislelizumab) given before surgery for people with HPV-positive oropharyngeal cancer. The goal is to help the immune system fight the cancer and potentially improve outcomes after surgery.
Chengdu, SichuanAges 18 years+ - NCT07563439RecruitingPhase 2
PollenVax Shot for Mugwort Pollen Allergies
This study tests a new allergy shot (PollenVax) given under the skin to treat seasonal allergies caused by mugwort pollen. If you have moderate-to-severe mugwort allergies confirmed by testing, this trial may help reduce your symptoms during pollen season.
Almaty, AlmatyAges 18–65 - NCT07568184Recruiting
New Exosome Treatment for Sudden Hearing Loss
This trial tests a new way to deliver anti-inflammatory medicine directly into the ear using tiny particle carriers called exosomes. It's designed for people who lost hearing suddenly without a clear cause and didn't improve with standard steroid pills.
Kafr ash Shaykh, EgyptAges 18–65 - NCT07567274Enrolling by invitationPhase 2
DMSO Therapy for Ringing in Ears After COVID
This trial tests a combination therapy using DMSO (a chemical that penetrates tissues) mixed with several medications to treat persistent ringing in the ears (tinnitus) that developed or worsened after COVID-19 infection or vaccination. If you have bothersome tinnitus linked to long COVID or vaccine injury and haven't responded to previous treatments, this study may help.
Ithaca, New YorkAges 18–70 - NCT07560280Recruiting
Tinnitus from Jugular Vein Narrowing: Diagnosis and Surgery Study
This study evaluates whether neck vein narrowing causes a specific type of tinnitus (ringing in the ears) and tests surgical treatment. If you have persistent tinnitus and imaging shows a narrowed jugular vein, this trial may help determine if surgery could help.
Beijing, Beijing MunicipalityAges 18–75 - NCT07564388Enrolling by invitation
Predicting How Well Cochlear Implants Will Work for You
This research study tests whether certain thinking and hearing skills can predict how much benefit you'll get from a cochlear implant (a device that helps deaf or hard-of-hearing people hear). If you qualify, you'll take some tests that measure how your brain processes sound and language.
Chicago, IllinoisAges Up to 18 years - NCT06737549RecruitingPhase 4
Electroacupuncture and NGF for swallowing problems after stroke
This study tests whether a specific type of electroacupuncture (a gentle needle therapy with mild electrical pulses) plus a nerve growth factor injection can help people who have trouble swallowing after a recent stroke. The goal is to see if this combination improves swallowing function better than standard care.
Hangzhou, ZhejiangAges 18–80 - NCT07553247Recruiting
Comparing two airway tubes for young children under anesthesia
This study compares two types of soft breathing tubes (laryngeal mask airways) used during surgery in children ages 3–6. Researchers want to see which one works better and is safer for keeping the airway open during anesthesia.
Zagazig, Sharqia ProvinceAges 3–6 - NCT07557771Recruiting
Testing Middle Ear Function with Sound Waves
This research study tests a new way to measure how well your middle ear (the tiny bones behind your eardrum) works using sound waves instead of traditional hearing tests. It involves three groups: people with normal hearing, people with conductive hearing loss, and people scheduled for cochlear implant surgery.
LeuvenAges 18 years+ - NCT06738823Recruiting
Wii Fit vs. Vestibular Rehab for Vertigo Balance
This study compares two types of balance training—Wii Fit exercises and standard vestibular rehab—to see which helps people with BPPV (a common cause of vertigo). If you have moderate BPPV, you may join to help improve your balance.
IslamabadAges 30–60 - NCT07548944Recruiting
How Electrical Stimulation Affects Your Vision
This study watches how a treatment called transcorneal electrical stimulation (TES)—which uses gentle electrical pulses on your eye—affects your vision in the short term. You'll be observed while using the OkuStim device, and researchers will ask about any improvements you notice in your sight.
Frankfurt am MainAges 18 years+ - NCT07546682Recruiting
Propel Sinus Implant Study in Japan
This study tests a steroid-releasing implant placed during sinus surgery to help prevent inflammation and improve healing in patients with chronic sinus infections. If you're having sinus surgery in Japan, this trial may track how well the implant works for you.
AsahikawaAges 18 years+ - NCT07546045Recruiting
Robotic Surgery and Swallowing Recovery for Head and Neck Cancer
This trial tests a specialized robotic surgical approach for head and neck cancers, combined with personalized speech and swallowing rehabilitation. The goal is to remove tumors while preserving organ function and improving your ability to swallow and speak after surgery.
LausanneAges 18 years+ - NCT07545967RecruitingPhase 1
Re-radiation and Chidamide for Recurrent Head and Neck Cancer
This trial tests combining re-radiation (radiation therapy given a second time) with a drug called chidamide to treat head and neck cancer that has come back after previous radiation. The goal is to see if this combination can help patients whose cancer cannot be removed by surgery or who cannot have surgery.
Chengdu, SichuanAges 18–75 - NCT07549724Recruiting
Assessment tools for swallowing problems from brain conditions
This study tests new ways to evaluate and measure swallowing difficulties caused by neurological conditions like stroke or Parkinson's disease. Participating helps researchers develop better tools to diagnose and monitor swallowing problems in patients with these conditions.
Venezia, ItalyAges 18–85 - NCT07548268Recruiting
Ultrasound imaging for suspected throat cancer
This study tests a new ultrasound method to help doctors identify throat cancer earlier. You would undergo imaging scans to see if ultrasound can better detect cancer in the back of the throat.
AarhusAges 18 years+ - NCT06669611RecruitingPhase 3
Comparing two drug combos for advanced nasopharyngeal cancer
This trial tests whether a new drug combination (Nab-Paclitaxel with Camrelizumab) works better than the standard GP chemotherapy plus Camrelizumab for people whose nasopharyngeal cancer has come back or spread. The goal is to find a more effective treatment option.
Guangzhou, GuangdongAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.