Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT07489742Recruiting
Ondansetron lozenge vs IV for shivering prevention in tonsillectomy
This trial tests whether an ondansetron lozenge works as well as IV ondansetron to prevent shivering after tonsillectomy in children. It could offer a needle-free way to reduce side effects during recovery.
Tanta, El-GharbiaAges 4–15 - NCT07496112Enrolling by invitation
Bioactive glass for ear surgery cavity filling
This trial tests using a special glass material to fill in the cavity left after ear surgery, which can cause problems like drainage, dizziness, and trouble with hearing aids. The goal is to see if this material helps create a more stable ear.
Legnano, ItalyAges 18 years+ - NCT07491965Recruiting
Vitamin D and Benign Paroxysmal Positional Vertigo (BPPV)
This study looks at whether people with BPPV (a type of vertigo triggered by head movement) have lower vitamin D levels than those who don't have vertigo. Your participation may help clarify if vitamin D plays a role in BPPV.
SohagAges Any age - NCT07495436Recruiting
Video vs. direct laryngoscopy for children's breathing tubes
This study compares two ways of placing a breathing tube in children during surgery: using a video camera laryngoscope or a standard direct laryngoscope. If your child is having a planned surgery and needs a breathing tube, this trial may help determine which method is safer and easier.
Santiago de Compostela, A CORUÑAAges birth–16 hours - NCT07494370Recruiting
Adenoid surgery study in children
This study looks at children getting adenoid surgery (adenoidectomy) to see how different factors and surgical methods affect whether any adenoid tissue is left behind. It aims to help improve surgical outcomes.
Pavia, LombardyAges birth–18 years - NCT07498374Recruiting
Drug-eluting stent for eosinophilic sinusitis with nasal polyps
This trial tests a fully dissolvable stent that releases medication inside the sinuses after surgery. It is for patients with a specific type of sinusitis (eosinophilic) and nasal polyps who either need surgery or have had surgery and show early signs of inflammation returning.
Xi'an, ShaanxiAges 18–65 - NCT07489807Recruiting
Can mild hearing aids help with tinnitus?
This study tests if mild-gain hearing aids can reduce bothersome tinnitus in people with normal hearing. It aims to see if wearing these devices improves your tinnitus perception.
LyngbyAges 18 years+ - NCT07492914RecruitingPhase 2
Study of pre-surgery drugs for head and neck cancer
This trial tests two medications given before surgery for head and neck cancer. The goal is to see if shrinking the tumor beforehand improves outcomes. If you have operable head and neck squamous cell cancer and are generally healthy, you may be eligible.
Chengdu, SichuanAges 18 years+ - NCT07492719Recruiting
Swallowing exercises with visual feedback after stroke
This study tests whether special swallowing exercises with a visual feedback tool can help people who have trouble swallowing after a recent stroke. If you've had a stroke in the last 6 months and have trouble swallowing, this may help you regain strength.
AnkaraAges 18 years+ - NCT04733950Recruiting
Test how much effort listening takes with cochlear implants
This study measures how your brain and eyes respond when you listen and focus on sounds. It compares people using a cochlear implant with people who have normal hearing, to understand listening effort and attention.
ParisAges 18–80 - NCT06053190Recruiting
Clear speech and memory in older adults
This study is testing whether listening to clear speech (slow, precise) helps older adults understand and remember sentences better. If you're between 60 and 90, right-handed, and a native English speaker, this trial may help you or your loved one learn more about how to improve communication as you age.
Salt Lake City, UtahAges 60–90 - NCT05641441Recruiting
Study hearing side effects after targeted treatment for vestibular schwannoma
This study looks at how targeted brain/skull-base treatment for a vestibular schwannoma may affect hearing (ear “ototoxicity,” meaning damage to hearing). It may help doctors better predict and prevent hearing problems in people treated for this tumor.
GenevaAges 18 years+ - NCT06472713RecruitingPhase 2
Liposomal mitoxantrone with immunotherapy for advanced nasopharyngeal cancer
This trial tests a combination of a chemotherapy drug (mitoxantrone liposome) with an immunotherapy (PD-1 blocker) for people whose nasopharyngeal cancer has come back or spread and hasn't responded to previous treatments. The goal is to see if this combination can shrink tumors or slow cancer growth.
Zhuhai, GuangdongAges 18–70 - NCT06349889RecruitingPhase 2
Adebrelimab with chemo and radiation for high-risk nasopharyngeal cancer
This trial tests adding the immunotherapy drug adebrelimab to standard chemotherapy and radiation for people with a high-risk type of nasopharyngeal cancer (stage IVA). The goal is to see if this combination helps control the cancer better.
Xiamen, FujianAges 18–65 - NCT07487636Enrolling by invitation
4DryField PH in head and neck surgery
This trial tests if 4DryField PH, a substance used to control bleeding, helps patients having head and neck surgery. It aims to see if it reduces complications.
Taichung, TaiwanAges 18 years+ - NCT07472023Enrolling by invitationEarly Phase 1
Stem cell therapy for hearing loss and tinnitus
This trial tests a regenerative stem cell treatment for people with hearing loss, tinnitus, or inner ear injury. It aims to see if the therapy can improve hearing or reduce symptoms.
New York, New YorkAges Any age - NCT07479446Recruiting
Comparing two painkillers for nausea after brain surgery
This trial tests if a newer painkiller (oliceridine) causes less nausea after a specific type of brain surgery than the standard painkiller (sufentanil). If you are having CPA region surgery and will receive a patient-controlled pain pump, this study may help find a better option for managing pain with fewer side effects.
BeijingAges 18–65 - NCT07472998Recruiting
Heart rate changes in people with a specific dizziness condition
This study looks at heart rate differences in people who have brief episodes of spinning dizziness (BPPV) compared to healthy people. It aims to see if the dizziness affects how the heart responds.
Istanbul, KüçükçekmeceAges 18–65 - NCT07476209Recruiting
Salivary gland procedure vs light therapy for dry mouth from radiation
This trial compares two treatments—a salivary gland procedure (sialendoscopy) and a light therapy (photobiomodulation)—to prevent dry mouth caused by radiation therapy for head and neck cancer. If you are about to start radiation and meet the dose limits, you may be eligible.
AlexandriaAges 18 years+ - NCT07479680Recruiting
Chin-tuck exercise for swallowing after stroke
This trial tests a chin-tuck exercise (pressing your chin down against resistance) to improve swallowing function after a stroke. It includes both people with swallowing problems and healthy volunteers.
Taipei, TaipeiAges 18–90 - NCT06779799Recruiting
Study of vocal cord lesions in autoimmune disease patients
This study examines vocal cord lesions, like 'bamboo' nodes, that cause voice changes (dysphonia) in people with autoimmune diseases such as lupus or rheumatoid arthritis. It aims to better understand and characterize these lesions to improve diagnosis and treatment.
BrestAges 18 years+ - NCT03426579Recruiting
Testing sedation monitoring during anesthesia for children’s throat surgery
This trial looks at whether a monitoring method for how deeply a child is sedated matches how the child’s reflexes react during intravenous anesthesia. It may help anesthesiologists keep children safer and more comfortable during direct laryngoscopy procedures using medications like dexmedetomidine and remifentanil.
Edegem, AntwerpAges 1 month–8 years - NCT06776900Recruiting
Breathing tube placement: side vs. back in children
This study compares two ways of placing a breathing tube (fiberoptic intubation) in children during surgery: lying on their side versus lying on their back. It aims to see which position is easier and safer for kids having non-head-and-neck surgeries.
CairoAges 2–10 - NCT07471555Enrolling by invitation
Vascular access and intraosseous study for nursing students
This trial tests a teaching method for inserting a special needle into bone (intraosseous access) and regular IV lines. It is only for 4th year nursing students.
Valencia, ValenciaAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.