Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,366 recruiting studies in this area right now.
By phase
- Not applicable975
- Phase 2167
- Phase 398
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia72
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Allergic Rhinitis23
- Nasopharyngeal Carcinoma (NPC)23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke19
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)16
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University58
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen10
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida29
- Massachusetts21
- Illinois20
- Arizona17
- Texas17
- Colorado16
- Alabama15
Recruiting studies1,366 total
- NCT07259538RecruitingPhase 1
Safety study of VVN432 nasal spray
This trial tests a nasal spray called VVN432 in healthy volunteers and people with chronic sinusitis. It checks if the spray is safe and how the body processes it.
BeijingAges 18–55 - NCT07125755RecruitingPhase 3
Comparing Chemo plus Radiation vs. Radiation Alone for Head and Neck Cancer
This trial tests whether adding chemotherapy to radiation therapy after surgery can help prevent head and neck cancer from coming back. It is for people who have certain risk factors after their surgery but no signs of cancer spread.
Guangzhou, GuangdongAges 18–70 - NCT07262827Recruiting
Testing low energy audio streaming in new cochlear implant processors
This study tests new low-energy audio streaming features in two Cochlear sound processors (Nucleus 8 and Kanso 3). It looks at whether experienced cochlear implant users can accept and benefit from this feature in daily listening situations.
Sydney, New South WalesAges 18 years+ - NCT06517446Recruiting
Virtual reality therapy for one-sided inner ear balance problems
This trial tests if virtual reality-based optokinetic stimulation can help people with balance problems caused by reduced function in one inner ear. It may offer a new way to retrain your balance system.
KocaeliAges 18–65 - NCT06521190RecruitingPhase 2
Testing ACOU085 to prevent hearing loss from cisplatin chemotherapy
This trial tests a new drug called ACOU085 to prevent hearing loss in men with testicular cancer who are receiving cisplatin chemotherapy. If you meet the hearing and health criteria, you may be able to join and help see if this drug can protect your hearing.
Tübingen, Baden-WurttembergAges 18–45 - NCT07601412Recruiting
Understanding Immune Response to Respiratory Viruses in Older Adults
This study examines how the body's natural defense system (specifically a type of immune protein) responds to common respiratory viruses like flu and cold in older adults. Researchers will analyze nasal samples that are already being collected as part of routine care to better understand why older people sometimes have different immune responses to these infections.
LyonAges 60 years+ - NCT06829706Recruiting
Modified smell training for smell loss after a virus
This study tests a new way of doing smell training to help people whose sense of smell has not recovered after a viral illness. It may help you smell things better again.
BeijingAges 18–80 - NCT06831357Recruiting
Predicting Cancer Spread in Nasopharyngeal Cancer Using AI
This trial uses a deep learning computer model to look at tissue images and MRI scans to predict whether nasopharyngeal carcinoma may spread to other parts of the body. It may help doctors decide on the best treatment for people with certain stages of this cancer.
Guangzhou, GuangdongAges Any age - NCT07232680Recruiting
Immune profile study for nasopharyngeal cancer patients
This study looks at how the immune system responds to radiation therapy for nasopharyngeal cancer. It will use scans and blood tests to find markers that might predict how well treatment works.
Taoyuan City, TaiwanAges 18 years+ - NCT07225244Recruiting
Comparing balloon inflation points for tear duct surgery
This trial tests whether using four balloon inflation points during tear duct surgery works better than the standard two points for people with blocked tear ducts. It aims to improve tear drainage and reduce symptoms.
TaipeiAges 20 years+ - NCT07225023Recruiting
Physical therapy for dizziness in the ER
This trial tests whether having a physical therapist see you in the emergency room can help with dizziness. If successful, it could improve care for people with dizziness who go to the ER.
Chicago, IllinoisAges 18 years+ - NCT07377084Recruiting
Study of chemicals in head and neck cancer samples
This study looks at the chemical signatures (metabolomics) in blood and tumor tissue from people with head and neck cancer. It aims to find markers that may help predict treatment response or tailor future care.
NiceAges 18 years+ - NCT07705243RecruitingPhase 3
Maintenance therapy for advanced nasopharyngeal cancer
This trial tests a combination of two drugs (becotatug vedotin and an anti-PD1 immunotherapy) as maintenance treatment after initial chemotherapy for advanced nasopharyngeal cancer that has spread or returned. It's for people whose disease has not progressed after standard first-line treatment.
Guangzhou, GuangdongAges 18–75 - NCT07211997Recruiting
FebriDx test for fever and cold symptoms in children
This study tests a finger-prick blood test (FebriDx) to see if it can quickly tell whether a child's fever and cold symptoms are caused by a bacterial or viral infection. If it works, it could help doctors decide whether antibiotics are needed.
Colton, CaliforniaAges 2–11 - NCT07253532Recruiting
Vibration belt study for improving balance and walking
This study tests a belt that vibrates to help with balance and walking. It may help people with balance problems due to conditions like ataxia or inner ear issues.
Baltimore, MarylandAges 18–80 - NCT06676722RecruitingPhase 2
SBRT and two targeted drugs for advanced nasopharyngeal cancer
This trial tests a combination of focused radiation (SBRT) and two targeted drugs (nimotuzumab and tislelizumab) for people with nasopharyngeal cancer that has come back or spread to a few spots (1-5) after prior immunotherapy. It aims to see if this triple therapy can help control the disease when standard treatment has stopped working.
Xiamen, FujianAges 18–75 - NCT07184684RecruitingPhase 2/Phase 3
Nasal bacteria transplant for chronic sinusitis
This trial tests if transplanting healthy nasal bacteria from a donor can help people with chronic sinusitis. It aims to restore a healthy microbiome in the nose to reduce symptoms like congestion and discharge.
HelsingborgAges 18 years+ - NCT07267988Recruiting
Brandt-Daroff exercises with GANS for BPPV dizziness
This study tests whether adding Brandt-Daroff exercises (simple head movements you can do at home) to a standard treatment called GANS maneuver helps reduce dizziness and improve daily life for people with BPPV.
IslamabadAges 18–60 - NCT07147426RecruitingPhase 2
Tislelizumab plus chemo before surgery for head and neck cancer
This trial tests whether giving the immunotherapy drug tislelizumab with chemotherapy before surgery can help people with advanced head and neck cancer. The goal is to shrink the tumor enough to remove it completely during surgery.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06556225Recruiting
Surgery for isolated maxillary sinus issues
This trial looks at patients who need surgery for problems limited only to the maxillary sinus (a space behind your cheek). It aims to learn more about these specific sinus lesions.
SohagAges Any age - NCT07118579RecruitingPhase 4
Comparing two anesthesia drugs for kids' tonsil surgery
This study compares two newer sedation drugs (remimazolam and ciprofol) to see which one better prevents breathing or airway problems during and after tonsil surgery in children.
Wuhan, HubeiAges 2–12 - NCT07279441Recruiting
Cochlear Implants and Listening Effort Study
This study looks at how much mental effort it takes for people with normal hearing or a cochlear implant to listen in different situations. Researchers want to learn how hearing and thinking work together, which could help improve cochlear implant technology.
Waltham, MassachusettsAges 18–80 - NCT07100704RecruitingPhase 2
Nivolumab for recurrent olfactory neuroblastoma
This trial tests the drug nivolumab for people with a rare nasal tumor (olfactory neuroblastoma) that has come back or spread and cannot be treated with surgery or radiation. You must have already tried chemotherapy and it stopped working. The goal is to see if nivolumab can shrink the tumor or slow its growth.
Kashiwa, ChibaAges 18 years+ - NCT07290140Recruiting
Balloon treatment for chronic sinusitis
This trial tests a balloon coated with a medicine (paclitaxel) to treat chronic sinusitis. It may help reduce inflammation and improve sinus drainage in adults with long-lasting sinus problems.
Birmingham, AlabamaAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,366 recruiting otolaryngology studies from the U.S. registry right now, out of 2,207 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.