Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,366 recruiting studies in this area right now.
By phase
- Not applicable975
- Phase 2167
- Phase 398
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia72
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Allergic Rhinitis23
- Nasopharyngeal Carcinoma (NPC)23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke19
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)16
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University58
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen10
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida29
- Massachusetts21
- Illinois20
- Arizona17
- Texas17
- Colorado16
- Alabama15
Recruiting studies1,366 total
- NCT07309978Recruiting
Comparing ultrasound and physical measurements for predicting difficult airways
This study compares two methods—ultrasound of the upper airway and standard physical measurements—to predict which patients may have a difficult airway during surgery. The goal is to find a more reliable way to prepare for safe anesthesia.
AnkaraAges 18–99 - NCT05708755RecruitingPhase 2
Monitoring immune response to CMV after lung transplant
This Phase 2 study monitors how your immune system reacts to CMV (a common virus) after a lung transplant. It may help doctors understand which patients are better protected and could guide future treatments to reduce CMV-related complications.
New York, New YorkAges 18–99 - NCT06118554Recruiting
Testing a 3D-printed tool for better sinus rinses
This study tests whether a 3D-printed tool can help people with chronic sinusitis get better results from nasal rinses. It might help if your sinus rinses don't reach deep enough into your nasal passages.
Columbus, OhioAges 18–75 - NCT06115772Recruiting
HPV and genital health in women with HPV-positive throat cancer
This study looks at HPV-related health in the genital and anal areas of women who have HPV-positive oropharyngeal cancer, or are the female partners of someone who does. The goal is to better understand how HPV affects these areas over time.
Rochester, MinnesotaAges 18 years+ - NCT06118697Recruiting
Feasibility of aerodigestive stimulation therapy in NICU infants
This trial tests a new therapy to help NICU babies who are not yet feeding fully by mouth. It uses special monitoring to guide treatment and aims to improve feeding skills.
Columbus, OhioAges 1 day–8 months - NCT07726251Recruiting
Heart changes during jaw surgery
This study looks at how your heart and blood pressure change during a type of jaw surgery called bimaxillary orthognathic surgery. It will help doctors understand a reflex that can affect your heart rate during the procedure.
Kirikkale, KırıkkaleAges 18–40 - NCT06912698RecruitingPhase 3
Lower vs. standard radiation for early nasopharyngeal cancer
This trial compares a lower dose of radiation to the standard dose for people with early-stage nasopharyngeal cancer. It aims to see if a lower dose is just as effective while reducing side effects.
Guangzhou, GuangdongAges 18–70 - NCT07185061Recruiting
Sound treatment for chronic tinnitus
This study tests whether a special sound-based treatment can help people with chronic tinnitus (ringing in the ears). If your tinnitus has lasted more than six months and you don't have other ear or brain problems, you may be able to join.
Nanjing, JiangsuAges 18 years+ - NCT06641687Recruiting
Sweet comfort for babies during nose scope
This study tests if giving a sweet solution (sucrose) to babies can make a flexible nose scope exam more comfortable. It may help reduce pain and stress during the procedure.
Toronto, OntarioAges 1 month–1 year - NCT07032675Recruiting
Nasal cartilage reshaping trial for better breathing
This trial tests a low-temperature radiofrequency device to remodel nasal cartilage during surgery, aiming to improve nasal airflow. It is for adults undergoing nose surgery for function or appearance.
Indianapolis, IndianaAges 18 years+ - NCT07035626RecruitingPhase 1/Phase 2
Spermidine to prevent dry mouth from radiation therapy
This trial tests whether spermidine (a natural compound) can help prevent dry mouth caused by radiation treatment for head and neck cancer. It is for patients who will receive a significant dose of radiation to their saliva glands.
Chengdu, SichuanAges 18–80 - NCT07663409Recruiting
Studying markers in sinusitis patients having surgery
This study looks at tissue and blood samples from people with chronic sinusitis to find markers that could predict how the disease behaves. It may help doctors choose better treatments in the future.
AlexandroupoliAges 18 years+ - NCT06884592Recruiting
Predicting difficult breathing tube placement in septoplasty surgery
This study looks at factors that may predict difficult intubation (placing a breathing tube) in people having septoplasty surgery. It aims to find out how common this is and what signs might help doctors prepare better.
Başakşehir, IstanbulAges 18–65 - NCT05916235Recruiting
Laser light treatment for jaw pain from TMJ disorder
This trial tests whether a specific type of light therapy (called photobiomodulation/laser) can reduce pain from temporomandibular disorder (TMJ) affecting the jaw muscles. If you have jaw muscle pain for at least 3 months, the study will compare your symptoms while you follow the treatment and diary requirements.
Gainesville, FloridaAges 18–99 - NCT06784999RecruitingPhase 4
Pain relief after head and neck reconstructive surgery
This study compares two medicines, sufentanil and methadone, for pain control after head and neck surgery that uses a flap to rebuild tissue. The goal is to find which option works better and has fewer side effects.
Indianapolis, IndianaAges 18–80 - NCT06917755Recruiting
Virtual reality training for thyroid surgery
This trial tests if training with virtual reality helps surgical residents learn thyroid surgery better. It compares VR training to standard methods for residents who have finished their first year of training.
ThessalonikiAges Any age - NCT06100601Recruiting
Nervous System and Voice Disorder Study
This study looks at how the autonomic nervous system (the part that controls things like heart rate and sweat) might be linked to functional dysphonia, a voice problem with no clear physical cause. If you have this voice disorder and meet the health and lifestyle criteria, your participation could help improve understanding of the condition.
Ghent, East-FlandersAges 18–60 - NCT07546682Recruiting
Propel Sinus Implant Study in Japan
This study tests a steroid-releasing implant placed during sinus surgery to help prevent inflammation and improve healing in patients with chronic sinus infections. If you're having sinus surgery in Japan, this trial may track how well the implant works for you.
AsahikawaAges 18 years+ - NCT07532642Recruiting
Head Position Changes With Special Vision Lenses
This study tests whether special prismatic lenses (lenses that bend light in a specific way) can help improve head and neck posture in people with Postural Deficiency Syndrome. Researchers will take X-rays and measurements before and after using these lenses to see if your head position improves.
Lisbon, Lisbon DistrictAges 18 years+ - NCT07589660Recruiting
Online follow-up program after thyroid surgery
This study tests whether a structured online follow-up program helps patients recover better after thyroid surgery. You'll use your smartphone to check in with your care team instead of always coming to the hospital.
Chengdu, SichuanAges 18–75 - NCT07461467Recruiting
Managing breathing tube pressure to reduce throat problems in older adults
This study tests a way of managing the air pressure in a breathing tube mask used during surgery. The goal is to reduce throat and voice box problems after surgery in older patients.
Chongqing, Chongqing MunicipalityAges 60 years+ - NCT07470736Recruiting
Comparing intubation tools for difficult airways
This trial tests two different ways to help doctors put a breathing tube in a patient with a difficult airway. It compares using a video laryngoscope with a video stylet versus using a video laryngoscope with a fiberoptic scope in a simulated setting.
Kuala Lumpur, Bandar Tun RazakAges Any age - NCT07384611Recruiting
Predicting difficult airway in children before surgery
This study looks at ways to predict if putting a breathing tube in a child's windpipe during planned surgery will be difficult. It aims to help doctors prepare better and keep children safe.
AnkaraAges 1 day–12 years - NCT07494370Recruiting
Adenoid surgery study in children
This study looks at children getting adenoid surgery (adenoidectomy) to see how different factors and surgical methods affect whether any adenoid tissue is left behind. It aims to help improve surgical outcomes.
Pavia, LombardyAges birth–18 years
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,366 recruiting otolaryngology studies from the U.S. registry right now, out of 2,207 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.