Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT07368361Recruiting
Comparing surgery techniques for severe sinusitis with polyps
This study compares two different surgical techniques for treating severe sinusitis with nasal polyps. It's for people who have tried other treatments but still have symptoms.
Egypt, KafrelsheikhAges 18–75 - NCT07368179Enrolling by invitation
Neck Access Study for Kids
This study tests how doctors get emergency access to a child's neck. It may help doctors find the best method for fragile kids.
BernAges 25–65 - NCT07370337RecruitingPhase 2
Chemotherapy plus immunotherapy for ear canal cancer
This trial tests combining chemotherapy with the immunotherapy drug tislelizumab for advanced squamous cell carcinoma of the ear canal. It may help shrink tumors that haven't spread to other parts of the body.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07364747RecruitingPhase 2
Does acetylcysteine protect hearing during cisplatin chemo?
This trial tests if taking N-acetylcysteine (NAC) can help prevent hearing loss caused by high-dose cisplatin chemotherapy. If you're getting cisplatin and are between 18 and 70, you may be able to join.
Bangkok, BangkoknoiAges 18–70 - NCT07362979RecruitingPhase 2
Toripalimab with chemo for advanced nasopharyngeal cancer
This trial tests adding toripalimab (an immunotherapy) to two different platinum-based chemotherapy regimens as initial treatment for locally advanced nasopharyngeal carcinoma. The goal is to see if this combination is more effective than standard treatment.
Dongguan, GuangdongAges 18–70 - NCT07366281Recruiting
Study of a new adhesive after voice box removal surgery
This trial is testing a new adhesive used after surgery to remove the voice box (total laryngectomy). It aims to see if it helps with healing or comfort.
AmsterdamAges 18 years+ - NCT06844461Recruiting
Quality of life after acoustic neuroma treatment
This study looks at how acoustic neuroma and its treatments affect your quality of life, and whether you later regret the choices you made. Researchers want to know if follow-up or surgery makes a difference.
BolognaAges 18 years+ - NCT06846047Recruiting
Electrical stimulation for balance and walking
This study tests whether mild electrical stimulation of the inner ear (vestibular system) can help improve balance and walking. It may be a good fit if you have a condition like vertigo, multiple sclerosis, Parkinson's disease, or concussion-related balance issues.
Cupertino, CaliforniaAges 18–100 - NCT07356128Recruiting
How people with cochlear implants and hearing aids understand sound
This study tests how well children and adults can use sound from both ears when they have a cochlear implant in one ear and a hearing aid in the other (or a special device that combines both). It looks at how your brain makes sense of sounds to help improve hearing and speech understanding.
Oklahoma City, OklahomaAges 5 years+ - NCT07359287Recruiting
Study on antibiotic use for respiratory infections
This study tests a program to help doctors prescribe antibiotics more carefully for common respiratory infections like colds, flu, bronchitis, and sinusitis. It may lead to better treatment for you.
CaenAges Any age - NCT07357558Recruiting
Reproductive health experiences in adults with PCD
This study is a conversation-based research project to understand how reproductive issues affect adults with Primary Ciliary Dyskinesia (PCD), a rare lung condition. By sharing your experiences, you can help doctors and researchers better support patients like you.
SouthamptonAges 18 years+ - NCT07359586Recruiting
Laryngopharyngeal injury after breathing tube under anesthesia
This study looks at throat and voice box injuries that can happen after having a breathing tube during surgery. It may help doctors understand why some people experience hoarseness, sore throat, cough, or choking after non-ear-nose-throat operations.
Hangzhou, ZhejiangAges Any age - NCT06851247RecruitingPhase 2
Chemoradiation plus toripalimab for advanced nasopharyngeal cancer
This trial tests a new treatment for advanced nasopharyngeal cancer. You will get chemotherapy and radiation, followed by maintenance therapy with an immunotherapy drug called toripalimab to help your immune system fight the cancer.
Guangzhou, GuangdongAges 18–65 - NCT03707691Recruiting
Test training for pitch perception and memory abilities
This study looks at how people perceive musical pitch and how that relates to memory, and whether training can improve performance. It may help researchers learn why some people struggle with pitch-related tasks and what kinds of training work best.
BronAges 5–90 - NCT05312983Recruiting
Testing new hearing tests to better diagnose age-related hearing loss
This study is developing a set of hearing tests to more precisely identify age-related hearing loss. It may help you (or the study team) better understand what type of hearing problem you have and how to guide next steps.
ParisAges 18 years+ - NCT06264245Recruiting
Sound processing at work and hearing health study
This trial looks at how using platforms that change sound, like online meeting tools, might affect your hearing. It compares people who use these tools a lot with those who use them less.
BrusselsAges 18 years+ - NCT06854380RecruitingEarly Phase 1
Steroid and enzyme injection for vocal cord lesions
This trial tests if injecting a steroid combined with hyaluronidase into vocal cord lesions can help people with voice problems who cannot or will not do voice therapy. It's for those with small, non-cancerous growths who aren't candidates for surgery.
Al Mansurah, Dakahlia GovernorateAges 18–60 - NCT07348302RecruitingPhase 3
Allergy tablet for dust mite rhinitis and asthma
This trial tests an under-the-tongue tablet for people with dust mite allergies causing moderate to severe nasal symptoms or mild-to-moderate asthma. The goal is to see if it improves symptoms and can replace or reduce the need for allergy medicines.
Nueve de Julio, Buenos AiresAges 12–65 - NCT06856785Recruiting
Treating Voice Problems Without Surgery in Adults
This trial tests a therapy for adults with voice changes not caused by a physical illness. It looks at whether voice therapy can help people who have trouble with their voice but whose vocal cords are essentially healthy.
SohagAges 15–60 - NCT07351227Recruiting
Comparing devices for placing a breathing tube in children
This study compares two different devices used to help place a breathing tube in children during surgery. It aims to find out which device works better for young children having planned operations.
São Paulo, São PauloAges 6 months–3 years - NCT07350681Recruiting
Jaw surgery's effect on foot pressure and posture
This study looks at how jaw surgery (orthognathic surgery) affects your foot pressure and body posture. You might join if you are already planning this surgery as part of your orthodontic treatment.
Istanbul, FatihAges 18 years+ - NCT07340411RecruitingPhase 2
Herbal nose rinse after sinus surgery
This trial is testing whether rinsing the nose with a Chinese herbal medicine after surgery helps people with chronic sinusitis recover better. It compares the herbal rinse to usual care, with the goal of reducing symptoms and the need for more treatments.
TaichungAges 18–90 - NCT07340515RecruitingPhase 3
Proton vs standard radiation for advanced nasopharyngeal cancer
This trial is testing whether a newer, more precise type of radiation (proton therapy) works better than standard radiation (IMRT) for people with advanced nasopharyngeal cancer. It also includes chemotherapy and immunotherapy to see if the combination can improve outcomes.
Jinan, ShandongAges 18–70 - NCT07335874Recruiting
Hearing screening follow-up for congenital infection in newborns
This study checks if babies who fail their newborn hearing test might have a hidden infection from birth. It looks for cytomegalovirus (CMV), a common virus that can affect hearing, using a simple test.
StrasbourgAges birth–1 month
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.