Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT06248398Recruiting
Robot-assisted cochlear implant and hearing in noise
This trial tests whether a robot-assisted cochlear implant surgery improves how well you hear speech in noisy environments. If you have severe hearing loss in both ears and are a candidate for a cochlear implant, this study may help show if the robotic method leads to better hearing outcomes.
ParisAges 18 years+ - NCT06829147Recruiting
AI to diagnose lymph node spread in nasopharyngeal cancer
This trial tests whether a computer model can accurately detect if cancer has spread to lymph nodes in patients with nasopharyngeal carcinoma. It uses MRI and PET/CT scans taken before treatment to see if the AI can replace or supplement current methods.
Guangzhou, GuangdongAges Any age - NCT06829706Recruiting
Modified smell training for smell loss after a virus
This study tests a new way of doing smell training to help people whose sense of smell has not recovered after a viral illness. It may help you smell things better again.
BeijingAges 18–80 - NCT07393880Recruiting
Sound and training for chronic tinnitus
This trial combines sound therapy with electrical stimulation and auditory training to reduce chronic tonal tinnitus. It may help if you have had constant ringing in your ears for more than 3 months but less than 5 years.
Dublin, DublinAges 18–80 - NCT07392320RecruitingPhase 2
Immunotherapy or chemo pills after chemoradiation for high-risk nasopharyngeal cancer
This trial compares two options—a type of immunotherapy or a chemotherapy pill (capecitabine)—as maintenance treatment after standard chemoradiation for high-risk nasopharyngeal cancer. It aims to see which helps prevent the cancer from coming back.
Guangzhou, GuangdongAges 18–70 - NCT07391345Recruiting
MRI-Guided Radiation for Early Vocal Cord Cancer
This study tests a precise, MRI-guided radiation treatment for early-stage vocal cord cancer. It aims to deliver high-dose radiation more accurately to the tumor, possibly reducing side effects and improving outcomes.
KaunasAges 18 years+ - NCT07397234Recruiting
Awake breathing tube placement study
This study tests two ways to numb the neck for placing a breathing tube while you're awake. It might help if you have a difficult airway that makes regular intubation harder.
Nanjing, JiangsuAges 18–85 - NCT07389213Recruiting
Can brain stimulation and hearing aids slow memory loss in older adults with hearing loss?
This trial tests whether a non-invasive brain stimulation technique (rTMS) combined with hearing aids can help slow down thinking and memory decline in older adults who have age-related hearing loss.
Guangzhou, GuangdongAges 50–85 - NCT05997186Recruiting
Reinnervated flap for mouth and throat reconstruction
This trial tests a new way to rebuild parts of the mouth or throat after surgery, using a flap from the thigh that is reconnected to nerves to help it work better. It may help people who need a reconstructive procedure for these areas.
BaselAges 18 years+ - NCT06389201Recruiting
Hydroxychloroquine before radiation and chemo for NPC
This trial tests whether taking hydroxychloroquine (HCQ) before standard radiation and chemo can help treat advanced nasopharyngeal cancer. It is for patients who have not yet started any cancer therapy.
Nantong, JiangsuAges 20–70 - NCT06830187Recruiting
Bone density, vitamin D, and hearing loss in otosclerosis
This study looks at how bone density and vitamin D levels relate to hearing loss in people with otosclerosis, a condition where extra bone growth in the ear causes hearing problems. It may help doctors understand why some people lose more hearing than others.
AnkaraAges 18 years+ - NCT07379775Recruiting
Testing AAR for nasal obstruction surgery decisions
This trial tests whether a simple device that measures your breathing (AAR) is reliable enough to help doctors decide if surgery is needed for nasal obstruction. It looks at patients who already plan to have surgery to see if this test matches what the surgeon finds.
Draguignan, VarAges 18 years+ - NCT07380269Recruiting
Long-term study of cochlear implant outcomes
This study follows people who get a cochlear implant – a device that helps restore hearing. It tracks how well you hear over time and checks for any long-term benefits or problems.
ShanghaiAges Any age - NCT07383493Recruiting
Treatments for cold and sinus infections
This study tests treatments for the common cold, sinus pain, or sore throat caused by a virus. It compares different options to see which works best for reducing symptoms like runny nose, congestion, and cough.
Clermont-FerrandAges 18–70 - NCT07383350Enrolling by invitation
Information sheets for better communication on antibiotics
This study tests if using simple information sheets helps you and your doctor talk better about infections like sore throat, sinusitis, or bronchitis, and make wise decisions about antibiotics — so you only get them when truly needed.
AalborgAges 18 years+ - NCT07379866Recruiting
Nerve blocks for pain relief after tonsil removal in children
This trial tests if injecting numbing medicine near certain nerves in the head and neck can reduce pain after tonsil and adenoid surgery in children aged 5–13. It may help them recover more comfortably.
Cairo, GovernorateAges 5–13 - NCT06219200Recruiting
Voice analysis for swallowing screening in neurological patients
This trial is testing if automatic voice analysis can help screen for swallowing problems in people with neurological conditions like stroke, Parkinson's disease, or ALS. It may help identify who needs further swallowing evaluation.
Lissone, LombardyAges 18 years+ - NCT07371234RecruitingPhase 2
Low-dose radiation and immunotherapy before surgery for head and neck cancer
This trial tests a combination of low-dose radiation and an immunotherapy drug (similar to Keytruda) given before surgery for advanced head and neck cancer. The goal is to see if this approach can shrink tumors and improve outcomes.
GuangdongAges 18–75 - NCT07378657RecruitingPhase 3
Sirolimus for children with orbital malformation
This trial tests if sirolimus can help children with a certain type of eye socket malformation. It aims to find a better treatment for children aged 1 to 18.
Cairo, Cairo GovernorateAges 1–18 - NCT07377084Recruiting
Study of chemicals in head and neck cancer samples
This study looks at the chemical signatures (metabolomics) in blood and tumor tissue from people with head and neck cancer. It aims to find markers that may help predict treatment response or tailor future care.
NiceAges 18 years+ - NCT04016675Recruiting
Radiation before surgery for cancer of the tear sac
This trial studies giving radiation before surgery for malignant (cancerous) tumors of the tear sac. It may help shrink the tumor and improve how well treatment works when surgery is planned.
ShanghaiAges 18–80 - NCT06453343Recruiting
Comparing two surgical approaches for cochlear implants
This study compares two different surgical methods for placing a cochlear implant (a device that helps with hearing). It is for adults who have lost hearing after learning to speak and are eligible for a specific type of implant. The goal is to see which approach works best.
NijmegenAges 18 years+ - NCT06831357Recruiting
Predicting Cancer Spread in Nasopharyngeal Cancer Using AI
This trial uses a deep learning computer model to look at tissue images and MRI scans to predict whether nasopharyngeal carcinoma may spread to other parts of the body. It may help doctors decide on the best treatment for people with certain stages of this cancer.
Guangzhou, GuangdongAges Any age - NCT07368179Enrolling by invitation
Neck Access Study for Kids
This study tests how doctors get emergency access to a child's neck. It may help doctors find the best method for fragile kids.
BernAges 25–65
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.