Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,366 recruiting studies in this area right now.
By phase
- Not applicable975
- Phase 2167
- Phase 398
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia72
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Allergic Rhinitis23
- Nasopharyngeal Carcinoma (NPC)23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke19
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)16
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University58
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen10
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida29
- Massachusetts21
- Illinois20
- Arizona17
- Texas17
- Colorado16
- Alabama15
Recruiting studies1,366 total
- NCT06504888Recruiting
Does penicillin allergy affect sinus lift success?
This study looks at whether people with a penicillin allergy have a higher risk of sinus lift failure. It checks how well the sinus lift and any dental implants heal.
Sant Cugat del Vallès, BarcelonaAges 18 years+ - NCT06499987Recruiting
Surgery or stenting for severe airway narrowing
This study compares two ways to treat severe narrowing of the windpipe caused by a breathing tube or tracheostomy. One option is surgery to remove the narrowed part and reconnect the healthy ends. The other is placing a long-term tube (stent) to keep the airway open.
SohagAges 12–50 - NCT06499480Recruiting
Italian registry of allergy shots and drops
This trial collects information from people of all ages who have allergic rhinitis, conjunctivitis, or asthma and are prescribed allergy immunotherapy (shots or drops). The goal is to understand how these treatments work in real life.
Rozzano, MilanoAges 1 year+ - NCT06487104Enrolling by invitation
Using TrachPhone for people with a tracheostomy
This trial tests a device called TrachPhone that helps people with a tracheostomy speak more clearly. It may be a good fit if you are stable and breathing on your own through your trach tube.
LondonAges 18 years+ - NCT07635719Recruiting
Comparing surgical tools for tonsil and adenoid removal
This study compares different surgical tools used during tonsil and adenoid removal surgery in children. The goal is to see which tool works best and is safest for this common pediatric surgery.
The Bronx, New YorkAges 1–18 - NCT06427707RecruitingPhase 2/Phase 3
Adding propofol or ketamine to magnesium and lidocaine for nasal surgery
This trial tests whether adding propofol or ketamine to a standard combination of magnesium and lidocaine improves pain control and recovery for people having nasal surgery. It aims to find a better way to manage anesthesia and reduce side effects.
Cairo, Cairo GovernorateAges 18–60 - NCT06420258RecruitingPhase 4
Deeper intubation for cervical esophageal cancer removal
This study tests if inserting the endoscope deeper helps remove early-stage cervical esophageal cancer or precancerous cells more effectively. It may offer a safer, less invasive option for you.
Fuzhou, FujianAges 18–80 - NCT06052839RecruitingPhase 2
Pulsed chemo plus pembrolizumab for head and neck cancer
This trial tests a new way to give chemotherapy (pulsed doses) together with pembrolizumab (an immunotherapy) for people with head and neck cancer that has come back or spread and cannot be cured with local treatments. The goal is to see if this combination works better than standard approaches.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06370468Recruiting
Chronic Rhinitis study in Chinese adults
This study looks at chronic rhinitis (long-term stuffy or runny nose) in Chinese adults. It aims to understand how common it is and what causes it.
Wuhan, HubeiAges 18–70 - NCT06317493Recruiting
Hearing test using eye response in children
This study uses a simple eye test (pupillometry) to measure how well children hear. It may help improve hearing care for kids who are deaf or hard of hearing.
PadovaAges 4 months–3 years - NCT06986629Recruiting
Light or magnetic field therapy for chronic sinusitis
This trial tests two treatments—light therapy or pulsed magnetic fields—to see if they improve quality of life for adults with chronic sinusitis. It may help if your symptoms are mild to moderate and you have allergies.
CairoAges 20–40 - NCT06248398Recruiting
Robot-assisted cochlear implant and hearing in noise
This trial tests whether a robot-assisted cochlear implant surgery improves how well you hear speech in noisy environments. If you have severe hearing loss in both ears and are a candidate for a cochlear implant, this study may help show if the robotic method leads to better hearing outcomes.
ParisAges 18 years+ - NCT06237842Recruiting
Wearable sleep trackers for children and teens in São Paulo
This trial tests wearable devices to monitor sleep in children and teens. It may help make sleep tracking easier than a traditional sleep test.
São Paulo, São PauloAges 3–18 - NCT07187583RecruitingPhase 4
Reducing biologic doses for chronic sinusitis with polyps
This trial tests if patients with chronic sinusitis and nasal polyps can safely reduce how often they take their biologic medication (dupilumab or mepolizumab) after their disease has been partly controlled for at least a year.
AalborgAges 18 years+ - NCT06229730Recruiting
Normal balance and hearing in Danish children
This study measures normal balance and inner ear function in healthy children aged 6 months to 10 years. It helps doctors understand what is typical for kids, which can improve care for those with balance issues.
HerningAges 6 months–10 years - NCT05665777RecruitingPhase 2
Chinese herbs for long-lasting throat pain and irritation
This trial tests if Chinese medicine can help people with ongoing throat pain, dryness, or a lump-like feeling that lasts more than 3 weeks. You may qualify if you have moderate to severe throat discomfort and fit specific Chinese medicine patterns.
Hong KongAges 18 years+ - NCT05391932Recruiting
Better decisions for dizziness and balance
This study tests whether a special training program can help people with dizziness and balance problems make better decisions about their movements. If you have inner ear balance issues, you may be able to join this short-term study.
Missoula, MontanaAges 40 years+ - NCT07288580RecruitingPhase 1/Phase 2
Gene therapy for children with inherited deafness
This trial tests an injection called EHT102 for children who have severe or profound hearing loss due to mutations in the Otoferlin gene. The goal is to see if the treatment can restore or improve hearing.
Shanghai, Shanghai MunicipalityAges 1–17 - NCT06151743RecruitingPhase 2
Testing drug combo before throat cancer surgery
This trial tests a new combination of drugs (an immunotherapy called a PD-1 inhibitor, cetuximab, and platinum chemotherapy) given before surgery for advanced throat cancer that requires removing the voice box. The goal is to see if this treatment shrinks the tumor and improves outcomes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06129864RecruitingPhase 3
Study of Volrustomig for advanced head and neck cancer after chemoradiation
This trial tests a new drug called volrustomig (MEDI5752) for people with advanced head and neck cancer that was not removed by surgery and has been treated with chemoradiation. The goal is to see if the drug can help prevent the cancer from coming back.
Birmingham, AlabamaAges 18–130 - NCT07058116RecruitingPhase 1
BNCT radiation therapy for head and neck cancer
This trial tests a type of radiation therapy called BNCT (boron neutron capture therapy) for people with head and neck cancer that cannot be surgically removed. It may be an option if you have already had radiation or chemo and have no distant spread of cancer.
HelsinkiAges 18 years+ - NCT07308015RecruitingPhase 4
Hyaluronic acid nasal rinse for dry nose
This trial tests if a sodium hyaluronate nasal spray helps people with dry nose symptoms like crusting, bleeding, and stuffiness. It may be an option if your nose feels dry and has thick mucus or scabs.
Changchun, JilinAges 18–75 - NCT06492252Recruiting
Speech learning and memory study
This study tests how well healthy adults learn and remember new speech patterns. You will say sounds or words, and we will measure how your brain controls speech.
New Haven, ConnecticutAges 18–40 - NCT07055373Recruiting
Nerve stimulation for chronic whiplash pain
This trial tests if a gentle nerve stimulation device on the ear can reduce neck pain and disability in people with long-term whiplash symptoms. It aims to find a safe, non-drug option for pain relief.
Calgary, AlbertaAges 18–65
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,366 recruiting otolaryngology studies from the U.S. registry right now, out of 2,207 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.