Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT07070479RecruitingPhase 2
Combination treatment for PD-1 resistant nasopharyngeal cancer
This trial is testing a combination of drugs for people whose nasopharyngeal cancer has stopped responding to standard treatments like platinum chemotherapy and PD-1 inhibitors. It aims to find a new effective approach for advanced or recurrent disease.
Guangzhou, GuangdongAges 18–70 - NCT07068048Enrolling by invitation
Steroid wash during thyroid surgery to protect voice nerves
This trial tests if rinsing the surgical area with a steroid drug (dexamethasone) during thyroid surgery can help prevent damage to the nerve that controls your vocal cords. It may lower the risk of voice changes after surgery.
Petaling Jaya, SelangorAges 18–80 - NCT07073664Enrolling by invitation
Endoscopic sinus expansion plus Stapokibart for chronic sinusitis
This trial tests if a new drug (Stapokibart) combined with a sinus surgery improves symptoms like nasal congestion, discharge, and loss of smell in people with type 2 chronic sinusitis.
Changchun, JilinAges 18–75 - NCT07067268RecruitingPhase 2
Tislelizumab and capecitabine for nasopharyngeal cancer with remaining EBV DNA
This trial tests a combination of two drugs, tislelizumab and capecitabine, for people with nasopharyngeal cancer who still have detectable EBV DNA in their blood after finishing radiation therapy. The goal is to see if this treatment can help clear the virus and improve outcomes.
Shanghai, ChinaAges 18 years+ - NCT06749899RecruitingPhase 3
Immunotherapy with chemoradiation for advanced nasopharyngeal cancer
This trial tests a combination of a new immunotherapy (QL1706) plus standard chemoradiation for people with advanced nasopharyngeal cancer that hasn't spread to distant organs. The goal is to see if adding this drug helps control the cancer better than standard treatment alone.
Fuzhou, FujianAges 18–65 - NCT03979235Recruiting
Rehab effectiveness programs for people after stroke
This trial is testing rehabilitation programs by studying how well they work for people with movement problems after a stroke. You may be able to join if you can complete the rehab assessment and follow testing instructions.
BeijingAges 18–80 - NCT05418218Recruiting
International headache registry for people with headache diagnoses
This study collects information from people who have headaches to better understand different headache types. You may help researchers by keeping headache records and allowing follow-up over time.
Hangzhou, ZhejiangAges 4–99 - NCT07058116RecruitingPhase 1
BNCT radiation therapy for head and neck cancer
This trial tests a type of radiation therapy called BNCT (boron neutron capture therapy) for people with head and neck cancer that cannot be surgically removed. It may be an option if you have already had radiation or chemo and have no distant spread of cancer.
HelsinkiAges 18 years+ - NCT06986629Recruiting
Light or magnetic field therapy for chronic sinusitis
This trial tests two treatments—light therapy or pulsed magnetic fields—to see if they improve quality of life for adults with chronic sinusitis. It may help if your symptoms are mild to moderate and you have allergies.
CairoAges 20–40 - NCT07055373Recruiting
Nerve stimulation for chronic whiplash pain
This trial tests if a gentle nerve stimulation device on the ear can reduce neck pain and disability in people with long-term whiplash symptoms. It aims to find a safe, non-drug option for pain relief.
Calgary, AlbertaAges 18–65 - NCT07060261Recruiting
Pre-op MRI for HPV+ tonsil cancer surgery
This trial is looking at whether an MRI before surgery can help improve outcomes for people with HPV-positive tonsil cancer who are undergoing robotic surgery (TORS). The results may help doctors better plan surgery to remove all cancer.
Cleveland, OhioAges 18 years+ - NCT07059195Recruiting
Keeping Neck Bent After Windpipe Surgery
This study tests two simple, non-invasive methods to keep your neck in a comfortable bent position after windpipe surgery. The goal is to reduce tension where the windpipe is reconnected, which may help the area heal better.
SohagAges 6 months–80 years - NCT07057258Enrolling by invitation
Injection vs. surgery for laryngeal clefts in children
This trial compares two treatments for children who have a gap in their voice box (laryngeal cleft) that causes liquid to go into their lungs. One treatment is an injection to close the gap, and the other is surgery with stitches.
Portland, OregonAges 1–10 - NCT07063212RecruitingPhase 2
Sacituzumab govitecan plus cetuximab for head and neck cancer
This trial tests a combination of two drugs—sacituzumab govitecan and cetuximab—for people with advanced head and neck cancer that has gotten worse after immunotherapy. The goal is to see if this new treatment can shrink or slow the cancer.
Basking Ridge, New JerseyAges 18 years+ - NCT07056582Recruiting
Pain relief before nasal surgery: ketamine vs. dexmedetomidine
This trial tests two inhaled medicines given before surgery to see which one works better for pain after nasal surgery. One medicine is ketamine and the other is dexmedetomidine, both given as a mist through a nebulizer.
SohagAges 20–60 - NCT07064096Recruiting
Mental imagery plus balance rehab for dizziness in young adults
This study tests whether adding mental imagery (picturing movements in your mind) to standard balance exercises can help young adults with a one-sided inner ear balance problem feel less dizzy and improve their balance.
Gujar Khān, Punjab ProvinceAges 20–40 - NCT07055542Recruiting
New tool to predict thunderstorm asthma risk
This research study aims to create a simple tool to predict who is at risk for thunderstorm asthma. You will be asked to track your allergy symptoms and medications online during the spring, plus do a lung function test and give a blood sample.
Albury, New South WalesAges 18–70 - NCT07055191Recruiting
Mouth versus neck thyroid surgery comparison
This study compares a new, scarless mouth surgery for thyroid removal with the standard neck incision. It looks at how well each works and how safe they are.
BobignyAges 18–65 - NCT07059351Recruiting
Mouth health and pneumonia risk after stroke
This study looks at how oral health affects the chances of developing pneumonia after a stroke and how well people recover their ability to swallow. It may help find ways to prevent complications and improve recovery for stroke survivors with swallowing problems.
GhentAges 18 years+ - NCT07048418Recruiting
Nose job results in adults born with a cleft lip and palate
This trial asks adults who had a nose job as teens or children, after being born with a cleft lip and palate, to rate how they look and feel about their nose. Their answers will help doctors understand how these surgeries affect patients long-term.
MontpellierAges 18–30 - NCT07053176Enrolling by invitationPhase 4
Neck injection for dizziness linked to neck pain
This trial tests whether a local anesthetic injection in the neck (paravertebral lidocaine) can reduce dizziness that is related to neck pain or stiffness. It may help if your dizziness started along with neck pain, trauma, or limited movement.
Fara in Sabina, RietiAges 18–80 - NCT05946057Recruiting
Registry study for people with otoferlin hearing loss
This study builds a patient registry and tracks the natural history of hearing loss in people whose genetic test shows changes in the otoferlin (OTOF) gene. It may help researchers understand how hearing symptoms progress over time and improve future treatments.
Goettigen, Lower SaxonyAges Any age - NCT07041671Recruiting
Can a mouth spray reduce virus in breath?
This trial tests whether ColdZyme mouth spray can lower the amount of virus you breathe out when you have a cold or flu-like illness. It may help you recover faster and reduce spreading the virus to others.
LundAges 18 years+ - NCT07039435Recruiting
Perceptual adaptation after cochlear implant
This study looks at how people adapt to hearing with a cochlear implant. It's for adults who are getting one implant in one ear while the other ear has normal or near-normal hearing.
New York, New YorkAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.