Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,371 recruiting studies in this area right now.
By phase
- Not applicable978
- Phase 2168
- Phase 399
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia73
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Nasopharyngeal Carcinoma (NPC)24
- Allergic Rhinitis23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke20
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)17
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University59
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida30
- Massachusetts21
- Illinois20
- Texas18
- Arizona17
- Colorado16
- Alabama15
Recruiting studies1,371 total
- NCT06098482Recruiting
Testing speech understanding with a mobile app for hearing device users
This study uses a smartphone app to test how well adults who use hearing aids or cochlear implants can understand speech. It aims to see if the app is a reliable way to measure hearing performance, which could make future check-ups easier and more convenient.
Lone Tree, ColoradoAges 18 years+ - NCT06112509Recruiting
Balance changes after gamma-knife for ear tumor
This study looks at how your balance might change after gamma-knife radiosurgery for a vestibular schwannoma. You will have follow-up balance tests to see if the treatment affects your balance over time.
BesançonAges 18–90 - NCT06112860Recruiting
Over-the-counter hearing aids for memory loss study
This trial tests whether over-the-counter hearing aids can help people with mild memory loss (mild cognitive impairment or mild dementia) who also have hearing loss. You and a communication partner will participate together to see if improving hearing can also help with thinking and communication.
Evanston, IllinoisAges 60–90 - NCT06114706Recruiting
Better assessment of sore throat and antibiotic use
This study tests a new way to assess sore throats in primary care and pharmacies to help decide when antibiotics are needed. It aims to improve treatment and reduce unnecessary antibiotic use.
StenungsundAges 6 years+ - NCT06117254Recruiting
Hearing aids for Veterans with trouble hearing in noise
This trial tests whether hearing aids help Veterans who have trouble hearing in noisy places but whose hearing loss is not severe. You'll visit the VA Portland Medical Center several times to see if the aids improve your daily life.
Portland, OregonAges 18–79 - NCT06123650Recruiting
Magnetic brain stimulation plus therapy for swallowing after stroke
This study tests whether adding a gentle magnetic brain stimulation (called rTMS) to standard swallowing therapy can help prevent pneumonia in people who have trouble swallowing after a stroke. It might reduce the risk of getting a lung infection.
Giza, Giza GovernorateAges 49–65 - NCT06126627Recruiting
Brain and voice study for teachers with vocal fatigue
This study looks at how vocal fatigue affects the brain and voice in teachers. It uses MRI and voice tests to understand these changes.
BonnAges 21–39 - NCT06129552Recruiting
Healthy nose cells study for sinusitis insight
This study is looking at healthy people to understand how certain cells in the nose work. It will compare them to people with sinus problems to learn what goes wrong in chronic sinusitis with nasal polyps.
LeuvenAges 18 years+ - NCT06130176Recruiting
Single-step sinus and dental surgery for tooth-related sinusitis
This trial tests a combined procedure to fix sinus infections caused by tooth problems. If you have chronic sinusitis from a dental issue that hasn't improved with other treatments, this surgery might help by addressing both the tooth and sinus in one operation.
Buraidah, Qassim ProvinceAges 18 years+ - NCT06137378RecruitingPhase 2
Pembrolizumab for advanced throat cancer to avoid laryngectomy
This trial tests whether a drug called pembrolizumab (Keytruda) can help people with advanced throat cancer avoid removal of the voice box. You may be eligible if you have a specific type of larynx or hypopharynx cancer that hasn't been treated with radiation or immunotherapy before.
Mannheim, Baden-WürtembergAges 18–70 - NCT06163807Recruiting
Asthma and nasal polyps long-term observation study
This study follows people with asthma (with or without nasal polyps) to learn more about how the disease changes over time. If you already take part in the MEGA cohort or use a biologic drug for severe asthma, this may be a way to contribute to research while continuing your normal care.
Santiago de Compostela, AcoruñaAges 18–80 - NCT06164483Recruiting
Hearing tests in people with MS or Parkinson's
This study checks how well people with multiple sclerosis (MS) or Parkinson's disease hear. It uses simple hearing tests to see if these conditions affect hearing.
Catania, SicilyAges 20–40 - NCT06170021Recruiting
Radiation ear problems in throat cancer patients
This study looks at how often radiation therapy for throat cancer causes middle ear infections or fluid buildup. It aims to understand and track these ear problems in patients getting a precise type of radiation called IMRT.
Guangzhou, GuangdongAges 18–70 - NCT06174038Recruiting
Hearing aids for memory and hearing loss study
This study tests whether hearing aids can help people with both hearing loss and early memory problems. It lasts for a period of time, and you will be asked to wear hearing aids daily.
New York, New YorkAges 55–75 - NCT06177301RecruitingPhase 3
Comparing two drug combos for recurrent nasopharyngeal cancer
This study compares two combinations of drugs (tislelizumab plus either GX or GP) to see which works better for people with nasopharyngeal cancer that has returned or spread and has not been treated with systemic therapy before.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06182657Recruiting
Nasopharyngeal cancer response to induction chemotherapy
This study looks at how well nasopharyngeal cancer (NPC) responds to the first round of chemotherapy before other treatments. It aims to see if the amount of tumor shrinkage can help predict outcomes and guide future care for people with advanced NPC.
Nanchang, JiangxiAges 18 years+ - NCT06190171Recruiting
Breathing strength training for heart transplant patients
This trial tests whether a special breathing and muscle-strengthening exercise program can help people waiting for a heart transplant. It is designed to improve your respiratory strength and overall conditioning before surgery.
Nashville, TennesseeAges 18–90 - NCT06192771Recruiting
Swallowing and speech therapy after tongue cancer surgery
This trial tests whether starting speech and swallowing therapy early after surgery helps people with tongue cancer recover their ability to eat and talk. It is for patients having part of their tongue removed and rebuilt with a tissue flap.
Toronto, OntarioAges 18 years+ - NCT06197776Recruiting
Predicting treatment success for advanced nasopharyngeal cancer
This study uses advanced testing (multi-omics) to predict if combining chemoradiation with immunotherapy works better for nasopharyngeal cancer that has returned or spread. It aims to find the right treatment for each person.
Guangzhou, GuangdongAges 18–70 - NCT06219980RecruitingPhase 2
Radiation and immunotherapy before surgery for oral cancer
This trial tests combining radiation therapy with immunotherapy and chemotherapy before surgery for advanced oral or throat cancer. The goal is to see if this approach can shrink the tumor and improve treatment outcomes.
Guangzhou, GuangdongAges 18–70 - NCT06219200Recruiting
Voice analysis for swallowing screening in neurological patients
This trial is testing if automatic voice analysis can help screen for swallowing problems in people with neurological conditions like stroke, Parkinson's disease, or ALS. It may help identify who needs further swallowing evaluation.
Lissone, LombardyAges 18 years+ - NCT06226558Recruiting
Long-Term Health of Children with Congenital CMV in NY
This study will follow children born in New York State who were tested for cytomegalovirus (CMV) as newborns. It aims to understand their long-term health and development, whether they were confirmed to have CMV, a false positive, or even a late detection if born early.
Stony Brook, New YorkAges birth–1 year - NCT06228196Recruiting
Study of brain scans in people with BPPV
This study looks at people with a common inner ear dizziness problem called BPPV, and compares them to healthy volunteers. It uses brain scans and other tests to learn more about the condition.
Xi'an, ShaanxiAges 18–60 - NCT06228079RecruitingPhase 3
Chemo-immunotherapy after surgery for early reoccurring nasopharyngeal cancer
This study looks at whether adding chemo-immunotherapy after surgery is better than surgery alone for patients whose nasopharyngeal cancer has returned but is still in early stages. It may help prevent the cancer from coming back again.
Shanghai, Shanghai MunicipalityAges 18–75
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,371 recruiting otolaryngology studies from the U.S. registry right now, out of 2,216 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.