Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,371 recruiting studies in this area right now.
By phase
- Not applicable978
- Phase 2168
- Phase 399
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia73
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Nasopharyngeal Carcinoma (NPC)24
- Allergic Rhinitis23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke20
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)17
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University59
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida30
- Massachusetts21
- Illinois20
- Texas18
- Arizona17
- Colorado16
- Alabama15
Recruiting studies1,371 total
- NCT07584499RecruitingPhase 1
New drug test for children with EGFR-positive solid tumors
This study tests a new cancer drug called Becotatug Vedotin in children ages 2–18 with certain types of solid tumors (cancers that form in organs or tissues) that have an EGFR protein. The drug is designed to find tumors with this protein and attack cancer cells while sparing healthy ones.
Guangzhou, GuangdongAges 2–18 - NCT07590024RecruitingPhase 3
Personalized Cancer Treatment Guidance for Nasopharyngeal Cancer
This trial tests whether a special analysis of blood markers and imaging scans can help doctors choose the best combination of chemotherapy and radiation for nasopharyngeal cancer. The goal is to improve outcomes by tailoring treatment to each patient's specific cancer characteristics.
Beijing, Beijing MunicipalityAges 18–65 - NCT07599696Recruiting
Speech Amplification Devices for Parkinson Disease
This research study tests special amplification devices designed to help people with Parkinson disease or related conditions speak more clearly. The goal is to improve how well others can understand your speech.
East Lansing, MichiganAges 50 years+ - NCT07606547Recruiting
Swallowing Strength Training for Parkinson's Disease
This study tests whether a mouth and throat muscle-strengthening device called EMST helps people with Parkinson's disease who have difficulty swallowing. Stronger throat muscles may make swallowing safer and easier.
MünsterAges 18 years+ - NCT07618078Recruiting
Personalized Cancer Risk Assessment for Nasopharyngeal Cancer
This study helps doctors predict which patients with nasopharyngeal cancer (a cancer of the upper throat) will benefit most from additional chemotherapy after radiation treatment. It uses a special blood test and imaging to create a personalized risk score for each patient.
Beijing, Beijing MunicipalityAges 18–75 - NCT07620210Recruiting
Swallowing Therapy and Pressure Ball Training After Stroke
This study tests whether a swallowing therapy program (CTAR) combined with a pressure ball exercise helps older adults who had a stroke recover their ability to swallow safely. Many stroke survivors struggle with swallowing, which can lead to serious health problems, so this research aims to find better ways to help.
Tainan, Tainan CityAges 65–90 - NCT07620353Recruiting
Study of OROSEDAL for sore throat and mouth sores
This study observes how well OROSEDAL, a topical oral medication, works for sore throats and minor mouth ulcers or sores that have lasted less than 15 days. You'll be asked to track your pain relief while using the product your doctor prescribes.
Multiple LocationsAges 8 years+ - NCT07625423RecruitingPhase 1
Gene therapy injection for advanced head and neck cancer
This trial tests a new treatment where a specially designed virus carrying an anti-cancer gene is injected directly into tumors in the head and neck area. It's for patients whose cancer has come back or spread after prior chemotherapy and who cannot have surgery or radiation.
Chengdu, ChinaAges 18–65 - NCT07625462Recruiting
How hearing affects brain development in children
This research study looks at how hearing—whether typical or affected by hearing loss—shapes how children's brains grow and develop. Researchers will compare brain development in children with normal hearing, hearing aids, cochlear implants, and other hearing devices.
ShanghaiAges Up to 18 years - NCT07626437RecruitingPhase 3
Cold and Flu Symptom Relief Medicine Trial
This study tests a combination medicine containing pain reliever, caffeine, and allergy medication to help ease nasal congestion and other cold or flu symptoms. You'd take the medicine for a short period and report how well it works.
Belo Horizonte, Minas GeraisAges 18–60 - NCT07627087Recruiting
Balance and Navigation Skills After Vestibular Implant
This study tests how a vestibular implant—a small device that helps with balance—affects your ability to navigate spaces and your thinking skills. Researchers will give you cognitive tests before and after using the implant to see if it helps you move and think more clearly.
GenevaAges 18–80 - NCT07627399Recruiting
Best Care Practices for Stroke in Regular Hospital Units
This study tests whether following best-practice guidelines for stroke care in regular hospital units (rather than specialized stroke centers) helps patients recover better. Researchers will track how well patients do when they receive standardized stroke care protocols.
Antequera, MálagaAges 18 years+ - NCT07635368Recruiting
Blood Markers in Newborns With CMV Infection
This research study examines blood samples from newborns to identify biological markers (proteins and genetic signals) that could help detect and understand congenital cytomegalovirus (CMV) infection—a virus some babies are born with. Finding these markers might help doctors identify infected infants earlier and develop better treatments.
CopenhagenAges birth–4 weeks - NCT07637981RecruitingPhase 2
Safety Study of DX243 for Hearing Loss in Noise
This study tests a new medicine (DX243) to see if it is safe and well-tolerated in people with hearing difficulties, especially trouble hearing speech in noisy environments. The goal is to understand how the body processes this medicine and whether it might help improve hearing.
Liège, LiègeAges 18–75 - NCT07646119Recruiting
Understanding Hidden Hearing Loss in Older Adults
This study investigates 'hidden hearing loss'—a condition where people have normal standard hearing test results but still struggle to hear in difficult situations. Researchers want to understand this problem better in adults over 60 to potentially improve diagnosis and treatment.
Shanghai, Shanghai MunicipalityAges 60 years+ - NCT07603167Enrolling by invitation
Photon-Counting CT Scans for Laryngeal Cancer Staging
This study tests a new type of CT scanner (photon-counting CT) to better visualize laryngeal cancer before surgery. The goal is to improve how doctors stage and plan treatment for throat cancer.
RozzanoAges 18 years+ - NCT07579364Enrolling by invitation
Voice Outcomes After Vocal Cord Surgery
This study follows people who have had surgery to improve one-sided vocal cord paralysis or atrophy—a condition where one vocal cord doesn't move properly or has shrunk. Researchers track how well your voice works and your quality of life over 2 years after surgery.
La Jolla, CaliforniaAges 18 years+ - NCT07567274Enrolling by invitationPhase 2
DMSO Therapy for Ringing in Ears After COVID
This trial tests a combination therapy using DMSO (a chemical that penetrates tissues) mixed with several medications to treat persistent ringing in the ears (tinnitus) that developed or worsened after COVID-19 infection or vaccination. If you have bothersome tinnitus linked to long COVID or vaccine injury and haven't responded to previous treatments, this study may help.
Ithaca, New YorkAges 18–70 - NCT07511998Enrolling by invitation
Comparing endotracheal tube sizes to reduce sore throat after surgery
This study compares different sizes of a specialized breathing tube (endotracheal tube) used during surgery to see which size causes less sore throat afterward. If you're having elective surgery under general anesthesia, this trial may help reduce your post-surgery discomfort.
Daegu, DaeguAges 20–70 - NCT07503613Enrolling by invitation
Long-term follow-up for AAVAnc80 gene therapy
This study follows people who already received the experimental AAVAnc80-antiVEGF gene therapy for vestibular schwannoma. It monitors long-term safety and effects of the treatment.
Dallas, TexasAges 18 years+ - NCT07500311Enrolling by invitation
Comparison of a new sound management feature for Med-El cochlear implants
This trial tests if a new automatic sound feature helps people with Med-El cochlear implants hear better in different environments. It compares performance with the feature turned on versus off.
Chapel Hill, North CarolinaAges 18 years+ - NCT07472023Enrolling by invitationEarly Phase 1
Stem cell therapy for hearing loss and tinnitus
This trial tests a regenerative stem cell treatment for people with hearing loss, tinnitus, or inner ear injury. It aims to see if the therapy can improve hearing or reduce symptoms.
New York, New YorkAges Any age - NCT07445204Enrolling by invitation
Electrical stimulation for swallowing after stroke
This trial tests whether a gentle electrical stimulation technique on neck muscles can help improve swallowing in people who recently had a stroke. It may be a good option if you are still having trouble swallowing after your stroke.
IstanbulAges 18 years+ - NCT07417267Enrolling by invitation
Clean Air Study for Lung Health in CF or PCD
This study tests whether using air cleaners in your home can improve lung health for people with cystic fibrosis (CF) or primary ciliary dyskinesia (PCD). It takes place in Cyprus and requires you to stay at home most days.
Nicosia, AglantziaAges 6 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,371 recruiting otolaryngology studies from the U.S. registry right now, out of 2,216 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.