Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,252
- Phase 3131
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy53
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California143
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT06879444Enrolling by invitation
Core strength and pelvic floor in Sjogren's
This study looks at how core stability and pelvic floor muscles work in people with primary Sjogren's syndrome. If you have this condition, the results may help doctors understand changes in muscle function.
Denizli, DenizliAges 18–65 - NCT06860659Enrolling by invitationPhase 4
Hyaluronate eye drops for moderate to severe dry eye
This trial tests whether 0.28% sodium hyaluronate eye drops can help people with moderate to severe dry eye feel better. It's for patients who have significant dry eye symptoms and signs on an eye exam.
Bangkok, BangkokAges 18 years+ - NCT06844240Enrolling by invitation
Testing the safety and effectiveness of the XEN63 gel implant for glaucoma
This study tests a new gel implant (XEN63) to lower eye pressure in adults with open-angle glaucoma. It may be an option if your eye pressure remains high despite using eye drops, or if you can't tolerate the drops.
Acquaviva delle Fonti, ItalyAges 18 years+ - NCT06827535Enrolling by invitation
Long-term study of eye changes in glaucoma and high eye pressure
This study tracks changes in blood flow, structure, and vision over time in people with glaucoma or high eye pressure. It aims to understand how these conditions progress, which could help improve future treatment.
Milan, ItalyAges 18 years+ - NCT06796673Enrolling by invitation
Retina biobank study for vitreoretinal disease
This study collects retina fluid samples from people getting treatment for a vitreoretinal disease. It aims to find better ways to understand and manage these conditions.
Bellaire, TexasAges 18 years+ - NCT06751615Enrolling by invitation
Improving scleral lens fit with advanced imaging
This study tests whether using advanced imaging can help make scleral contact lenses fit better for people with certain eye conditions. If you have keratoconus, an irregular cornea after a transplant, or severe dry eye and have struggled with other lens types, this may be for you.
MadridAges 18 years+ - NCT06744478Enrolling by invitation
Misight contact lenses for children with different vision between eyes
This trial tests whether Misight 1 Day contact lenses can help children and young adults whose eyes have different prescriptions (anisometropia). It looks at how much the vision difference changes over 24 months of wearing the lenses.
Hualien CityAges 8–23 - NCT06737354Enrolling by invitationPhase 1
Study of IVB103 injection for wet age-related macular degeneration
This trial tests a new treatment called IVB103 for people with wet age-related macular degeneration (AMD). It aims to see if the injection is safe and effective for those who have already had anti-VEGF therapy. You may qualify if you have active disease and have had at least two prior anti-VEGF treatments.
Chengdu, SichuanAges 50 years+ - NCT06731582Enrolling by invitationPhase 3
Nicotinamide supplement study for glaucoma patients
This trial tests whether a vitamin B3 supplement called nicotinamide can help slow down vision loss in people with glaucoma. It is for those with moderate disease who are already on treatment.
Singapore, Central SingaporeAges 21 years+ - NCT06693882Enrolling by invitation
Electrical stimulation for glaucoma
This study tests if mild electrical stimulation of the optic nerve can help people with moderate to advanced glaucoma. It may be an option if your glaucoma has gotten worse despite standard treatments.
San Francisco, CaliforniaAges 18 years+ - NCT06693856Enrolling by invitation
Steroid pulse therapy for active Graves' eye disease
This study tests whether high-dose steroid pulses (given through a vein) can help people with moderate to severe Graves' eye disease that is still active. It is for people who have not yet been treated with steroids and whose eye problems began within the past year.
Shanghai, Shanghai MunicipalityAges 25–70 - NCT06689397Enrolling by invitation
Study of Epstein-Barr virus-related pink eye
This trial is studying a specific type of eye infection (pink eye) caused by the Epstein-Barr virus. It aims to better understand the condition and may help guide treatment for people with these symptoms.
LondonAges 16 years+ - NCT06685328Enrolling by invitation
Minimal surgery with gel for macular hole
This study tests a new, less-invasive surgery for macular holes. The surgeon uses a tiny gel to help close the hole without removing as much gel-like fluid from your eye as usual. It may help your vision recover with less risk.
Chengdu, SichuanAges 18 years+ - NCT06682455Enrolling by invitation
Predicting AMD progression with advanced scans and AI
This study is looking at people with intermediate AMD who previously took part in the PINNACLE study. It will use advanced eye scans and machine learning to learn more about how AMD progresses and how to predict it.
ViennaAges Any age - NCT06650358Enrolling by invitation
Outcomes for patients with LAL+ lens implants
This study looks at how the LAL+ lens implant performs in people who have had cataract surgery in both eyes and have completed light adjustments for the LAL+ lens. It aims to gather information on vision results and safety.
Wilkes-Barre, PennsylvaniaAges Any age - NCT06649799Enrolling by invitation
Comparing two lasers for cataract surgery in older adults
This study tests two different femtosecond lasers (LenSx and Z8) used during cataract surgery to see how they affect the eye's natural response, including inflammation and pupil size. It is designed for adults over 50 with age-related cataracts of moderate hardness.
Hangzhou, ZhejiangAges 50–80 - NCT06643858Enrolling by invitation
Normal Chinese Lifespan Brain Chart Study
This study creates a 'normal brain map' by taking MRI scans of healthy people of all ages. It helps doctors understand what a healthy brain looks like at different stages of life.
Beijing, Beijing MunicipalityAges 6–90 - NCT06636019Enrolling by invitation
Contact lens for nearsightedness and eye thickness
This trial tests whether a special contact lens can slow down nearsightedness by measuring changes in the thickness of the back layer of your eye. It may help you understand if this lens works for your vision.
AugsburgAges 18 years+ - NCT06631807Enrolling by invitation
How blindness affects sleep, dreams, and spatial skills
This study looks at how the number of years a person has been blind affects their sleep, dreams, and spatial abilities. It may help us understand how the brain adapts when vision is lost, which could lead to better support for people with visual impairments.
GenovaAges 18–85 - NCT06597071Enrolling by invitation
Eye movement test to help diagnose Parkinson's-like conditions
This study uses a simple eye-tracking test to see if eye movement patterns can help tell the difference between Parkinson's disease and similar conditions like PSP or MSA. It aims to find a faster, easier way to diagnose these disorders.
SevilleAges 30–80 - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT06578884Enrolling by invitation
Testing a new toric lens for cataract and astigmatism
This study tests a new toric intraocular lens (a replacement lens for the eye) designed to fix both cataracts and corneal astigmatism (an uneven cornea that blurs vision). If you are planning cataract surgery or a lens exchange and have astigmatism that needs correcting, this lens may be an option for you.
GyőrAges 18 years+ - NCT06578117Enrolling by invitation
Visual training for stroke-related vision loss
This study tests whether a computer-based visual training program can help people who have lost vision after a stroke to their brain's visual center. You must have been in a prior study with the same team.
Rochester, New YorkAges 21–75 - NCT06545305Enrolling by invitation
Eye problems in homocystinuria patients, 2018–2022
This study looks at eye problems in people with homocystinuria. It will review medical records from 2018 to 2022 to find out how common eye issues are and what might increase the risk.
JeddahAges 20–30
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,924 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.