Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT02317328Recruiting
Adaptive eye imaging to take very detailed retinal pictures
This study uses special “adaptive optics” equipment to capture very detailed images of the retina (the nerve layer at the back of the eye). It may help improve eye tests for people with eye disease and also includes some healthy volunteers.
Bethesda, MarylandAges 12–120 - NCT02521311RecruitingPhase 2
Clemastine to help restore nerve covering in optic neuritis
This Phase 2 trial tests whether clemastine can help regrow the protective covering around the optic nerve after acute optic neuritis (an inflammation-related vision problem). It may help improve vision recovery and signal how well “remyelination” happens.
San Francisco, CaliforniaAges 18–55 - NCT02357238Recruiting
Study of genetics in people with uveitis
This study looks at genetic (inherited) differences in people with uveitis. The goal is to better understand what may cause uveitis and potentially help with future treatments.
Cleveland, OhioAges 6 years+ - NCT02422875Enrolling by invitation
Study of immune markers in autoimmune disease and lupus
This study looks at blood and immune cell markers (autoantibodies and immune cell “signatures”) to better understand autoimmune conditions, including lupus. It may help researchers identify which markers are linked to disease and how immune cells respond after vaccination.
Atlanta, GeorgiaAges 18 years+ - NCT02435940Recruiting
Registry for inherited eye vision conditions
This study is a registry, meaning it collects information about people with inherited retinal (retina) diseases. It may help researchers learn how these conditions progress and connect you with future studies or treatments.
Columbia, MarylandAges Any age - NCT02605785Recruiting
Imaging study to track tau protein in PSP
This study uses brain imaging to look at a protein called tau in people with progressive supranuclear palsy (PSP). It aims to better understand the disease and how tau changes over time, which may help future treatments.
Rochester, MinnesotaAges 35 years+ - NCT01432847Recruiting
Collecting eye-related samples to study eye diseases
This study collects samples like blood and a small skin biopsy (and sometimes urine, hair, or saliva) to better understand causes of eye diseases. The goal is to study eye conditions and may help researchers build better tests or treatments.
Bethesda, MarylandAges 1 day–120 years - NCT01496625Recruiting
Biobank study for retinal diseases and comparison samples
This study collects and stores blood and eye-related medical information to help researchers better understand retinal diseases, including age-related macular degeneration and diabetic retinopathy. Your samples may also be used to compare people with retinal disease to people without it.
Bethesda, MarylandAges 2–120 - NCT02077894Recruiting
Genetic testing to help identify inherited eye conditions
This study uses whole exome and whole genome genetic tests to look for DNA changes linked to inherited or congenital eye problems. It may help families and doctors better understand the cause of the eye condition and guide future care.
Bethesda, MarylandAges 1 day–120 years - NCT01425892Recruiting
Study of how Sjogren’s disease starts and changes over time
This study follows people with Sjogren’s disease to understand how it develops and how symptoms naturally change over time. The goal is to improve understanding and future care rather than provide a new immediate treatment.
Bethesda, MarylandAges 16–100 - NCT01617408Recruiting
Brain stimulation and vision testing in healthy adults
This study uses brain stimulation and brain imaging (MRI) along with vision tests to understand how the brain supports seeing. You might be eligible if you are a healthy adult and can safely complete MRI and stimulation tasks.
Bethesda, MarylandAges 18–50 - NCT01778543Recruiting
Study genes behind small eyes and eye coloboma
This study looks at how genes may cause certain eye conditions called microphthalmia, anophthalmia, and uveal coloboma. You may qualify if you have one of these conditions or are a close, unaffected relative who could also carry the gene.
Bethesda, MarylandAges 1–100 - NCT01757132Enrolling by invitation
Mini telescope implant study for advanced age-related macular loss
This post-approval study tests whether an implantable mini telescope can improve vision in people with advanced age-related macular degeneration that affects the center of vision. You may qualify if your vision loss matches a specific pattern and you can complete required eye training before and after surgery.
Chandler, ArizonaAges 65 years+ - NCT01746537Recruiting
Eye imaging test in people with uveitis
This study uses a special eye scan (optical coherence tomography) to look at inflammation in the front part of the eye. It may help doctors better measure uveitis activity and guide care by improving how inflammation is seen on scans.
Cleveland, OhioAges Any age - NCT02118922Recruiting
Testing a light-scanning eye exam to diagnose corneal thinning
This study tests whether a special “Brillouin” microscope scan can spot corneal ectasia and related cornea conditions. It may help doctors diagnose problems earlier and better sort out who needs closer eye care.
Boston, MassachusettsAges 20–75 - NCT01401998Recruiting
Study collecting information from people with ARPKD
This study looks at medical records, imaging, and genetic testing for people with autosomal recessive polycystic kidney disease (ARPKD). It may help researchers better understand the condition and how it affects the liver and kidneys.
Washington D.C., District of ColumbiaAges Up to 18 years - NCT01694940Recruiting
Mitochondrial disease registry and sample collection study
This trial builds a large database and collection of lab results, and possibly tissue samples, from people with suspected or diagnosed mitochondrial conditions. It helps researchers learn more about these disorders and mitochondrial DNA changes, which may improve future diagnosis and treatments.
San Diego, CaliforniaAges Any age - NCT01866371Recruiting
High-detail eye scans for children and adults
This study tests a high-resolution imaging method that takes very detailed pictures of the retina (the light-sensing layer at the back of the eye). You might benefit by getting your eye health checked in a structured imaging study—if you’re able to comfortably complete the scan.
Philadelphia, PennsylvaniaAges 7 years+ - NCT01654159Enrolling by invitation
Study of vision and lens optics during cataract surgery
This study looks at how well your vision works and how different cataract surgery lens choices perform. It may help researchers better understand what affects sight after cataract surgery.
Birmingham, West MidlandsAges 40–85 - NCT02138669Recruiting
Prescription cornea insert for keratoconus when vision worsens
This trial tests whether prescription inserts placed in the cornea can improve day-to-day vision for people with keratoconus whose vision is getting worse and who have few options left. You may be able to avoid or delay corneal transplant depending on your cornea shape and thickness.
Dallas, TexasAges 18 years+ - NCT01957267Recruiting
Eye imaging study for glaucoma detection
This study uses advanced eye scans to compare the eyes of people with glaucoma against those with healthy eyes. It aims to find better ways to detect and monitor glaucoma, which could help preserve vision.
Portland, OregonAges 40–85 - NCT00305305Recruiting
Brain development study for rare brain conditions
This study looks at how the brain develops in people with certain rare conditions that affect brain structure. It may help researchers understand these conditions better and could lead to improved care.
San Francisco, CaliforniaAges Any age - NCT00254605Recruiting
Retinal photo imaging for inherited eye conditions
This study uses special pictures of the back of your eye (retinal imaging) in people with inherited retinal degeneration. It may help researchers learn how these conditions look and change over time, and it can be a way for you to receive detailed eye imaging.
San Francisco, CaliforniaAges 13 years+ - NCT00341744Recruiting
Access to learning for children with low vision
This trial aims to help children with low vision access the visual environment needed for school, especially for learning to read. It may help by supporting how vision is used for reading in everyday school activities.
Nashville, TennesseeAges 3–21
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.