Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,252
- Phase 3131
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy53
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California143
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT07229001Enrolling by invitation
Treating Severe MGD in Children and Teens
This trial studies a treatment for severe Meibomian Gland Disease (MGD) in children and teens. MGD affects the tiny oil glands in your eyelids, which can cause dry, irritated eyes. The goal is to find a safe and effective way to help young patients with this condition.
Chicago, IllinoisAges 6–18 - NCT07217249Enrolling by invitation
Donor diabetes and cornea transplant success at 5 years
This study looks at how a donor's diabetes might affect the long-term success of a specific type of cornea transplant called DMEK. Participants from an earlier study (DEKS) will be followed for up to 5 years to see how well the transplant is doing.
Atlanta, GeorgiaAges 30–93 - NCT07212010Enrolling by invitation
Brain-related vision problems in children
This study looks at how brain injuries or abnormalities affect vision in children. It aims to better understand and diagnose cerebral visual impairment (CVI), a vision problem caused by brain issues rather than eye problems.
Cincinnati, OhioAges 6 months–6 years - NCT07198126Enrolling by invitation
How pterygium surgery changes corneal curvature in astigmatism
This trial compares how the curve of your cornea (which affects vision) changes before and after surgery to remove a pterygium—a fleshy growth on the eye—and repair the area with your own tissue. It is for adults with moderate to advanced pterygium that has already caused astigmatism.
Lahore, Punjab ProvinceAges 30–70 - NCT07171710Enrolling by invitation
Cyclosporine eye drops and tear duct plugs for dry eye in Sjögren's
This trial tests if using special eye drops (cyclosporine) along with tiny plugs placed in the tear ducts can improve dry eye symptoms in people with Sjögren's syndrome. The goal is to see if this combination works better than the drops alone.
Tianjin, Tianjin MunicipalityAges Any age - NCT07170683Enrolling by invitation
Vision test study for macular eye disorders
This study uses a special vision test called microperimetry to track how well the macula (the center of the retina) works in people with certain eye conditions like geographic atrophy or diabetic eye disease. Healthy volunteers are also needed for comparison. The goal is to understand how these conditions affect retinal function over time.
Nottingham, NottsAges 21 years+ - NCT07165626Enrolling by invitation
Retina measurements after epiretinal membrane removal surgery
This study checks how the retina changes after surgery to remove a wrinkled layer (epiretinal membrane). It's for people who already have had cataract surgery and are having the membrane removed because their vision is warped or blurry.
SzczecinAges 18–80 - NCT07133737Enrolling by invitation
5-year follow-up of SMILE for farsightedness
This study checks how your eyes are doing 5 years after a SMILE procedure to correct farsightedness (hyperopia). If you took part in the original PHOBOS study, this is a one-time follow-up visit to see how well the procedure held up.
ZlínAges Any age - NCT07119723Enrolling by invitation
Study on environment and nearsightedness in Uyghur children
This trial looks at how things in the environment might affect nearsightedness (myopia) in Uyghur children living in remote parts of China. If your child is between 6 and 15 and has no other eye problems, this study could help understand what causes myopia and how to prevent it.
TianjinAges 6–15 - NCT07109609Enrolling by invitationPhase 2
Testing Menthol on Skin to Increase Tears
This study tests whether applying menthol to the skin on your cheeks can help increase tear production. If you have dry eyes but are not under an eye doctor's care for it, this trial might be a fit.
Toronto, OntarioAges 18 years+ - NCT07096232Enrolling by invitation
AI vs doctor for eye surgery and keratoconus diagnosis
This study compares an AI system to a specialist eye doctor to see which is better at diagnosing vision problems like nearsightedness, farsightedness, astigmatism, and keratoconus. Your existing medical records will be used to see how well the AI performs.
Cairo, MaadiAges Any age - NCT07088705Enrolling by invitation
Subthreshold laser for retinitis pigmentosa
This trial tests a gentle laser treatment (SML) for people with retinitis pigmentosa (RP), an inherited eye disease that slowly causes vision loss. The goal is to see if the laser can help slow or improve vision problems like night blindness and tunnel vision.
SzczecinAges 18–70 - NCT07076277Enrolling by invitation
Comparing vision after different cataract lens implants
This study compares two types of advanced artificial lens implants used during cataract surgery. It looks at how well people see after getting one type of lens in one eye and the other type in the other eye, compared to getting the same type in both eyes.
Baltimore, MarylandAges 18 years+ - NCT07073937Enrolling by invitation
Three-year results of combined microstent and canaloplasty surgery
This trial is checking how well a combined eye surgery (Hydrus microstent plus canaloplasty plus cataract surgery) works over 3 years. It looks at long-term safety and effect on eye pressure. It's for people with open-angle glaucoma who already had that specific combination of procedures.
Salt Lake City, UtahAges 18 years+ - NCT07056738Enrolling by invitation
Ganglion Cell Loss Study in Retinitis Pigmentosa
This study looks at whether a type of retinal cell (ganglion cells) degenerates in people with retinitis pigmentosa. The goal is to learn more about the progression of the disease over time.
GöttingenAges 18 years+ - NCT07007897Enrolling by invitation
Cataract treatment observation study
This study is for people with cataracts who are planning to get treatment. It will observe your eye health and treatment process without giving you any new medicine.
Mesa, ArizonaAges 21 years+ - NCT07003685Enrolling by invitation
Glaucoma drainage device for hard-to-treat glaucoma
This study tests a posterior chamber drainage device for people with glaucoma that is not controlled by eye drops, especially those who have already had cataract surgery. It aims to help lower eye pressure safely and prevent further vision loss.
Ho Chi Minh City, Ho Chi MinhAges 18 years+ - NCT06985264Enrolling by invitation
Dry eye after upper eyelid surgery: muscle vs fat removal
This trial compares how two different upper eyelid surgery techniques—removing muscle versus removing fat—affect dry eye symptoms after surgery. It may help you understand which approach is better for your eye health.
Mersin, ÇukurovaAges 18–80 - NCT06969586Enrolling by invitation
Eye drops study for Fuchs corneal disease and glaucoma
This study tests whether special eye drops (Rho-kinase inhibitors) can improve the health of the cornea in people who have both Fuchs endothelial corneal dystrophy and glaucoma. The drops may help reduce corneal swelling and preserve your vision.
ZagrebAges 40–90 - NCT06951087Enrolling by invitationPhase 3
Steroid injection for diabetic retinopathy with cataract surgery
This trial tests if an injection of dexamethasone (a steroid) into the eye, before or during cataract surgery, can help treat mild to moderate diabetic retinopathy in people with type 2 diabetes.
Nantong, JiangsuAges Any age - NCT06938542Enrolling by invitation
Palliative care needs for kids with rare diseases
This study asks children with rare diseases and their families about what kind of palliative care (comfort and support) they need. It aims to understand how to better help families through their child's illness.
Washington D.C., District of ColumbiaAges 1–99 - NCT06931444Enrolling by invitation
Children's eye study in Beijing
This study will follow healthy primary school students for several years to understand how children's eyes develop and how to prevent vision problems. It involves a simple eye exam with drops to check for any issues.
Beijing, Beijing MunicipalityAges 6–12 - NCT06927544Enrolling by invitation
Gas bubble treatment for large macular holes
This trial tests a gas bubble procedure to repair large macular holes in people aged 50 and older. It aims to improve vision by closing the hole without traditional surgery.
OdesaAges 50–90 - NCT06925477Enrolling by invitation
New vs. standard laser for open-angle glaucoma
This study compares a new way of doing laser treatment for open-angle glaucoma versus the standard method. The goal is to see which approach works better at lowering eye pressure and protecting vision.
Charleston, South CarolinaAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,924 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.