Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,022 recruiting studies in this area right now.
By phase
- Not applicable7,998
- Phase 2485
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure565
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)144
- Acute Ischemic Stroke141
- Pulmonary Hypertension102
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama198
- Massachusetts181
- Arizona176
- New York165
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,019 total
- NCT06818240Recruiting
Can brain stimulation improve walking after stroke?
This study tests whether a gentle electrical current applied to the scalp (called tDCS) can improve your ability to walk while doing a second task, like talking or carrying something. It is for people who have had a stroke and can walk on their own.
Hong Kong, ChinaAges 50–80 - NCT06818435Recruiting
Registry study of the Myval heart valve for severe aortic stenosis
This study is tracking how well the Myval valve works in people with severe aortic stenosis who get it through a minimally invasive procedure called TAVI. It helps doctors learn more about the valve's safety and performance in real-world use.
CarnaxideAges 18 years+ - NCT06818474RecruitingPhase 4
Lanadelumab to prevent acquired angioedema attacks
This trial tests if lanadelumab can prevent swelling attacks in people with acquired angioedema (AAE). Acquired angioedema is a rare condition that causes sudden swelling in the skin and other body parts. This medicine is given as a long-term shot to lower the number of attacks you have.
Cincinnati, OhioAges 18 years+ - NCT06818669Recruiting
Heart risk study for Black adults with food insecurity
This study tests if giving small rewards for buying healthy food and taking medicines can lower heart disease risk in African American adults who have trouble getting enough food. You will get help with food costs and health coaching.
Buffalo, New YorkAges 18 years+ - NCT06818760Recruiting
Remote monitoring for pregnant women with heart conditions
This study tests if a wrist wearable can safely monitor pregnant women with congenital heart disease. It aims to improve care during pregnancy, delivery, and after birth by tracking health data remotely.
Cleveland, OhioAges 18 years+ - NCT06819618Recruiting
Predicting heart failure outcomes with machine learning
This trial uses machine learning to analyze data from a smartwatch to predict how heart failure progresses. It may help doctors better understand your condition and tailor treatments.
Goettigen, Lower SaxonyAges 18 years+ - NCT06819657Recruiting
Remote ischemic conditioning after aneurysm surgery
This trial tests a safe, non-invasive treatment called remote ischemic conditioning (using a blood pressure cuff on your leg) to see if it helps brain recovery after aneurysm surgery. It might reduce secondary damage and improve outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT06820515Recruiting
Blood disorder patient registry for all ages
This study is a registry (a large database) that collects information from people who have or may have a blood disorder. It helps researchers learn more about these conditions and improve care.
Hickory, North CarolinaAges Any age - NCT06820970Recruiting
Combined therapy for heart artery blockages that weren't fully opened
This trial tests if combining a new heart procedure with a special type of therapy called mindfulness therapy can help prevent heart problems in people with coronary artery disease that could not be fully fixed with stents or surgery.
Zhengzhou, HenanAges 18 years+ - NCT06821191RecruitingPhase 4
Safer blood thinner plan after heart stent
This trial is testing whether lowering the dose of your current blood thinner or switching to a different one (clopidogrel) is safer and works just as well after you've had a stent placed. It's designed for people who are already on two blood thinners and are doing well.
Jacksonville, FloridaAges 18 years+ - NCT06821399Recruiting
Better eye care for type 2 diabetes
This study is testing a better way to diagnose and manage eye problems (diabetic retinopathy) in people with type 2 diabetes. It aims to improve how doctors find and treat these issues to help protect your vision.
LanzhouAges 20–79 - NCT06821880Recruiting
Tracking infections and quality of life in blood cancer patients
This study uses a smartphone or web app to track infections and quality of life in people with multiple myeloma or chronic lymphocytic leukemia who have a weakened immune system. The goal is to create a better screening tool for infections and understand how the disease and treatment affect daily life.
Innsbruck, TyroliaAges 18 years+ - NCT06822205Recruiting
Treating narrowed arteries in transplanted kidneys
This trial tests a treatment for a condition that can happen after a kidney transplant, where the artery to the new kidney becomes narrowed. If you have been told you have this problem, the study may help find the best way to treat it.
BolognaAges 18 years+ - NCT06822400Recruiting
Study of Tetralogy of Fallot in Newborns
This trial looks at newborns with Tetralogy of Fallot, a heart condition present at birth. It aims to study the best way to treat these babies in the first month of life.
Beijing, Beijing MunicipalityAges 1 minute–6 months - NCT06822439Recruiting
Remote fetal monitoring for high-risk pregnancies
This study tests if remote monitoring of your baby's heartbeat from home is a safe and effective option for high-risk pregnancies. It may reduce the need for frequent hospital visits.
Boston, MassachusettsAges 18 years+ - NCT06822894Recruiting
3-vessel ultrasound flow study in heart disease patients
This trial uses a special ultrasound to measure blood flow in three main heart arteries. It may help doctors better understand blockages and improve treatment planning.
BeijingAges 18 years+ - NCT06822972RecruitingPhase 2
Study of Selinexor Plus Bispecific Antibody for Resistant Myeloma
This study tests the drug selinexor in combination with a bispecific antibody for multiple myeloma that has already been treated with at least 4 prior therapies. The goal is to see if the combination is safe and effective for patients whose disease has returned or hasn’t responded to previous treatments.
Durham, North CarolinaAges 18 years+ - NCT06823466Recruiting
Stroke study for patients on blood thinners
This study looks at people who had a stroke while taking blood thinners (anticoagulants) for an irregular heartbeat. It aims to learn more about these strokes and how to better prevent them in the future.
ZagrebAges 18 years+ - NCT06823570Recruiting
Exercise and blood pressure medicine for better blood vessels
This study is testing whether a combination of blood pressure medication and a supervised exercise program can improve the health of your blood vessels. It's for people with mild to moderate high blood pressure who are not already on medication.
Düsseldorf, DüsseldorfAges 18 years+ - NCT06825104Recruiting
Long-term comparison of two ablation methods for persistent AF
This long-term study follows people who already completed a 12-month study comparing two types of heart ablation for persistent atrial fibrillation. It looks at how well the treatments worked over time.
BronAges 18 years+ - NCT06825897Recruiting
Direct to angiography suite for stroke clot removal
This trial compares two ways to treat severe stroke patients with a large vessel blockage. One way is the standard approach of first imaging you and then deciding. The other way takes you directly to the angiography suite for immediate clot removal by the doctor. The goal is to see if this faster, direct approach helps you get better results.
Iowa City, IowaAges 18 years+ - NCT06826339RecruitingPhase 4
Advanced wound treatments for diabetic foot and leg ulcers
This study compares several advanced wound treatments (called CAMPs) plus standard care to standard care alone for hard-to-heal diabetic foot ulcers and venous leg ulcers. It aims to see if the extra treatments help wounds close faster and prevent complications.
Monroeville, PennsylvaniaAges 21 years+ - NCT06826872RecruitingPhase 2
Testing SPC1001 for essential hypertension
This trial tests an oral medication called SPC1001 to see if it can safely lower blood pressure in people with essential hypertension (high blood pressure not caused by another condition). It may help if you have mild to moderate high blood pressure.
SeoulAges 19–75 - NCT06826963Recruiting
Eccentric exercise for older adults with heart failure and muscle loss
This study tests whether a special type of exercise (eccentric, or lengthening, exercises) can help older adults with heart failure who also have muscle loss. It aims to see if the exercise is safe and improves strength and function.
Verona, VeronaAges 65–85
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,022 recruiting cardiology studies from the U.S. registry right now, out of 15,398 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.